• Title/Summary/Keyword: Shape Space

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Bio-Inspired Surface Modification of 3-Dimensional Polycaprolactone Scaffold for Enhanced Cellular Behaviors

  • Jo, Seon-Ae;Gang, Seong-Min;Park, Su-A;Lee, Hae-Shin
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.08a
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    • pp.202-202
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    • 2011
  • The research of 3-dimensional (3-D) scaffold for tissue engineering has been widely investigated as the importance of the 3-D scaffold increased. 3-D scaffold is needed to support for cells to proliferate and maintain their biological functions. Furthermore, its architecture defines the shape of the new bone and cartilage growth. Polycaprolactone (PCL) has been one of the most promising materials for fabricating 3-D scaffold owing to its excellent mechanical property and biocompatibility. However, there are practical problems for using it, in vitro and in vivo; extracellular matrix components and nutrients cannot penetrate into the inner space of scaffold, due to its hydrophobic property, and thus cell seeding and attachment onto the inner surface remain as a challenge. Thus, the surface modification strategy of 3-D PCL scaffold is prerequisite for successful tissue engineering. Herein, we utilized a mussel-inspired approach for surface modification of 3-D PCL scaffold. Modification of 3-D PCL scaffolds was carried out by simple immersion of scaffolds into the dopamine solution and stimulated body fluid, and as a result, hydroxyapatite-immobilized 3-D PCL scaffolds were obtained. After surface modification, the wettability of 3-D PCL scaffold was considerably changed, and infiltration of the pre-osteoblastic cells into the 3-D scaffold followed by the attachment onto the surface was successfully achieved.

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Characteristics of Particle Separation in Suspension using an Ultrasonic Standing Wave

  • Shin, Beom-Soo;Danao, Mary-Grace C.
    • Journal of Biosystems Engineering
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    • v.37 no.2
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    • pp.113-121
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    • 2012
  • Purpose: Particle separation in solution is one of important process in a unit operation as well as in an extract preparation for biosensors. Contrary to centrifuge-type of mesh-type filter, using an ultrasonic standing wave make the filtering process continuous and free from maintenance. It is needed to investigate the characteristics of particle movement in the ultrasonic standing wave field. Methods: Through the computer simulation the effects of major design and driving parameters on the alignment characteristics of particles were investigated, and a cylindrical chamber with up-stream flow type was devised using two circular-shape PZTs on both sides of the chamber, one for transmitting ultrasonic wave and the other for just reflecting it. Then, the system performance was experimentally investigated as well. Results: The speed of a particle to reach pressure-node plane increased as the acoustic pressure and size of particle increased. The maximum allowable up-stream flow rate could be calculated as well. As expected, exact numbers of pressure-node planes were well formed at specific locations according to the wavelength of ultrasonic wave. As the driving frequency of PZT got close to its resonance frequency, the bands of particles were observed clearer, which meant the particles were trapped into narrower space. Higher excitation voltages to the PZT produced a greater acoustic force with which to trap particles in the pressure-node planes, so that the particles gathered could move upwards without disturbing their alignments even at a higher inlet flow rate. Conclusions: This research showed the feasibility of particle separation in solution in the continuous way by an ultrasonic standing wave. Further study is needed to develop a device to collect or harvest those separated particles.

Continuous Axillary Branchial Plexus Block -I. Modification of catheter insertion method- (지속적 액와부 상완신경총 차단술 -I. 카테테르 삽입방법의 변형-)

  • Lee, Hoo-Jeon;Tae, Il-San
    • The Korean Journal of Pain
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    • v.10 no.2
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    • pp.225-230
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    • 1997
  • Background: Authors modified the traditional continuous axillary brachial plexus block technique of Selander for purpose of increasing success rate and decreasing complications by use of commercial epidural anesthesia set. Method: Thirty-nine patients scheduled for upper extremity operations were injected with 40 ml of anesthetic solution by axillary perivascular technique, using 23~25G immobile needle at 2 cm from the pectoralis major. Tuohy needle was immediately introduced at 4 cm from the pectoralis major and pierced the expanded neurovascular sheath at an angle of 30 degree to the skin. The "pop" was well noted well. Needle was advanced 0.5 to 3.0 cm and epidural catheter introduced through the needle. After removal of needle, occlusive dressing was done. Tip of catheter and spread of solution were demonstrated by fluoroscopy with contrast dye after completion of procedure. Result: Catheter insertion was successful at first attempt for all case. Total length of insertion was from 6 to 13($10.0{\pm}1.7$) cm. Tip of catheter was placed in infraclavicular space(66.7%), about the humeral head(17.9%) and in upper arm in 3 cases as U-shape(7.9%). Catheters were maintained for $6.7{\pm}2.6$(3-12) days. There were no complications such as: perforation of major vessels, needle trauma to nerve, infection, bleeding or hematoma. Conclusion: This study demonstrated continuous axillary brachial plexus block with epidural anesthesia set is safe, easy and convenient modification of technique of Selander.

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Numerical Study for Prediction of Rock Falls Around Jointed Limestone Underground Opening due to Blast Vibration (발파진동에 의한 절리암반 지하공동의 낙석발생 예측에 관한 수치해석적 연구)

  • Kim, Hyon-Soo;Kim, Seung-Kon;Cho, Sang-Ho
    • Explosives and Blasting
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    • v.34 no.3
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    • pp.10-16
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    • 2016
  • Recently, transition from open pit to underground mining in limestone mines is an increasing trend in Korea due to environmental issues such as noise, dust and vibrations caused by crushers and equipment. The severe damages in the surrounding rock mass of underground opening caused by explosive blasting may lead to rock fall hazards or casualties. It is well known that variables which mainly affect blast-induced rock falls in underground mining are: blast vibration level, joint orientation and distribution and shape of the cross sections of underground structures. In this study, UDEC program, which is a DEM code, is used to simulate blast vibration-induced rock fall in underground openings. Variation of joint space, joint angle and joint normal stiffness was considered to investigate the effect of joint characteristics on the blast vibration-induced rock fall in underground opening. Finally, jointed rock mass models considering blast-induced damage zone were examined to simulate the critical blast vibration value which may cause rock falls in underground opening.

Building Boundary Reconstruction from Airborne Lidar Data by Adaptive Convex Hull Algorithm (적응적 컨벡스헐 알고리즘을 이용한 항공라이다 데이터의 건물 경계 재구성)

  • Lee, Jeong-Ho;Kim, Yong-Il
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.30 no.3
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    • pp.305-312
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    • 2012
  • This paper aims at improving the accuracy and computational efficiency in reconstructing building boundaries from airborne Lidar points. We proposed an adaptive convex hull algorithm, which is a modified version of local convex hull algorithm in three ways. The candidate points for boundary are first selected to improve efficiency depending on their local density. Second, a searching-space is adjusted adaptively, based on raw data structure, to extract boundary points more robustly. Third, distance between two points and their IDs are utilized in detecting the seed points of inner boundary to distinguish between inner yards and inner holes due to errors or occlusions. The practicability of the approach were evaluated on two urban areas where various buildings exist. The proposed method showed less shape-dissimilarity(8.5%) and proved to be two times more efficient than the other method.

Magnetic resonance imaging-based temporomandibular joint space evaluation in tempormandibular disorders (측두하악관절증에서 자기공명영상을 이용한 측두하악관절의 관절강 평가)

  • Nah, Kyung-Soo
    • Imaging Science in Dentistry
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    • v.37 no.1
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    • pp.15-18
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    • 2007
  • Purpose : Disc and condylar position were observed on MRIs of temporomandibular joint disorder patients and condylar position agreement between MRI and tranascranal radiography was evaluated. Materials and Methods MRI and transcranial radiographs of both TM joints from 67 patients with temporemandibular disorder were used. On MRI, the position and shape of disc and condylar position as anterior, middle, posterior was evaluated at medial, center, and lateral views. On transcranial radiographs, condylar position was evaluated using the shortest distance from condyle to fossa in anterior, superior, and posterior directions. Results. 1. On MRI, 96 joints (71.6%) of 134 had anterior disc dispalcement with reduction and 38 joints (28.4%) without reduction. 2. Fourteen (14.6%) of 96 reducible joints showed anterior condylar position, 19 (19.8%) showed central position, 63 joints (65.6%) showed posterior position. Two joints (5.3%) of 38 non-reducible joints showed anterior condylar position, while 9 (23.7%) showed central position, and 27 (71.1%)-posterior position. 3. In 85 joints (63.4%) of 134, the transcranial condylar position agreed with that of the central MRI view, 10 joints (7.5%) with that of medial, 16 joints (11.9%) with that of lateral, and 23 joints (17.2%) disagreed with that of MRI. Conclusion : On MRT, most oi the reducible and non-reducible joints showed posterior condylar position. Transcranial radiographs taken with machine designed for TMJ had better agreement of condylar position with that of MRI. Extremely narrow joint spaces or very posterior condylar positions observed on transcranial radiographs had a little more than fifty percent agreement with those of MRIs.

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Seismic Response of Large Space Structure with Various Substructure (하부구조의 강성변화에 따른 대공간구조물의 지진거동)

  • Kim, Gee-Cheol;Kang, Joo-Won;Ko, Hyun
    • Journal of Korean Association for Spatial Structures
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    • v.10 no.3
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    • pp.81-90
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    • 2010
  • Large spatial structures have the different dynamic characteristics from general rahmen structures and many studies on dynamic behavior of it is conducted. But most studies was conducted about the particular shape of large spatial structures and, directly, the usable results of studies are very limited for seismic design of large spatial structures with the lower structure. So, this study is conducted about the truss arch structure that the basic dynamic characteristics of large spatial structure is inherent in, and the change of its seismic response is analyzed when columns have different length on both ends of it. According to the difference of column's length on both ends, the vertical acceleration response of truss arch structure is affected more than the horizontal acceleration response of it. Therefore, when the stiffness of lower structures that support the upper structure is different, the consideration of the vertical response is significantly required for the seismic design of large spatial structures.

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PHOTOMETRIC PROPERTIES OF FOUR NEW VARIABLE STARS IN THE VICINITY OF BR CAM

  • KIM S.-L.;LEE C.-D.;LEE J. W.;LEE J. A.;KANG Y.B.;KOO J.-R.;VAUCLAIR G.
    • Journal of The Korean Astronomical Society
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    • v.37 no.4
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    • pp.143-149
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    • 2004
  • We present photometric results for four new variable stars discovered in the vicinity of the ZZ Ceti-type pulsating white dwarf BR Cam. Observations were performed on 5 nights in November 2003 using the 1.8m telescope at Bohyunsan Optical Astronomy Observatory with no filter, on 3 nights in December 2003 using the 0.61m telescope at Sobaeksan Optical Astronomy Observatory with V, I filters, and on 3 nights in October 2004 using the 1.0m telescope at Mt. Lemmon Optical Astronomy Observatory with V, I filters. We estimated their periods from the phase-match technique for one eclipsing binary and the multiple frequency analysis for three pulsating stars. By considering the light curve shape, period and amplitude difference between two passbands, we classified the objects by their variability types as follows: V1 (USNO-A2.0 1425-05691757) is a W UMa-type eclipsing binary with an orbital period of $0^d.4641$; V2 (USNO-A2.0 1425-05703335) is a multi-periodic $\delta$ Set-type pulsating star with a dominant period of $0^d.0649$; V3 (USNO-A2.0 1425-05699659) is also a $\delta$ Set-type pulsating star with a period of $0^d.1408$; and V 4 (USNO-A2.0 1425-05707705) is a RR Lyr-type pulsating star with a period of $0^d.2643$.

Two-stage Content-based Image Retrieval Using the Dimensionality Condensation of Feature Vector (특징벡터의 차원축약 기법을 이용한 2단계 내용기반 이미지검색 시스템)

  • 조정원;최병욱
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.7C
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    • pp.719-725
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    • 2003
  • The content-based image retrieval system extracts features of color, shape and texture from raw images, and builds the database with those features in the indexing process. The search in the whole retrieval system is defined as a process which finds images that have large similarity to query image using the feature database. This paper proposes a new two-stage search method in the content-based image retrieval system. The method is that the features are condensed and stored by the property of Cauchy-Schwartz inequality in order to reduce the similarity computation time which takes a mostly response time from entering a query to getting retrieval results. By the extensive computer simulations, we have observed that the proposed two-stage search method successfully reduces the similarity computation time while maintaining the same retrieval relevance as the conventional exhaustive search method. We also have observed that the method is more effective as the number of images and dimensions of the feature space increase.

Evidence of Spin Reorientation by Mössbauer Analysis

  • Myoung, Bo Ra;Kim, Sam Jin;Kim, Chul Sung
    • Journal of Magnetics
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    • v.19 no.2
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    • pp.126-129
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    • 2014
  • We report the crystallographic and magnetic properties of $Ni_{0.3}Fe_{0.7}Ga_2S_4$ by means of X-ray diffractometer (XRD), a superconducting quantum interference device (SQUID) magnetometer, and a M$\ddot{o}$ssbauer spectroscopy. In particular, $Ni_{0.3}Fe_{0.7}Ga_2S_4$ was studied by M$\ddot{o}$ssbauer analysis for evidence of spin reorientation. The chalcogenide material $Ni_{0.3}Fe_{0.7}Ga_2S_4$ was fabricated by a direct reaction method. XRD analysis confirmed that $Ni_{0.3}Fe_{0.7}Ga_2S_4$ has a 2-dimension (2-D) triangular lattice structure, with space group P-3m1. The M$\ddot{o}$ssbauer spectra of $Ni_{0.3}Fe_{0.7}Ga_2S_4$ at spectra at various temperatures from 4.2 to 300 K showed that the spectrum at 4.2 K has a severely distorted 8-line shape, as spin liquid. Electric quadrupole splitting, $E_Q$ has anomalous two-points of temperature dependence of $E_Q$ curve as freezing temperature, $T_f=11K$, and N$\acute{e}$el temperature, $T_N=26K$. This suggests that there appears to be a slowly-fluctuating "spin gel" state between $T_f$ and $T_N$, caused by non-paramagnetic spin state below $T_N$. This comes from charge re-distribution due to spin-orientation above $T_f$, and $T_N$, due to the changing $E_Q$ at various temperatures. Isomer shift value ($0.7mm/s{\leq}{\delta}{\leq}0.9mm/s$) shows that the charge states are ferrous ($Fe^{2+}$), for all temperature range. The Debye temperature for the octahedral site was found to be ${\Theta}_D=260K$.