• 제목/요약/키워드: Set2

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Saccharomyces cerevisiae의 Swd2와 Set1의 결합이 Swd2의 이중적인 기능에 미치는 영향 (The effect of Swd2's binding to Set1 on the dual functions of Swd2 in Saccharomyces cerevisiae)

  • 박신애;이정신
    • 미생물학회지
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    • 제53권4호
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    • pp.286-291
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    • 2017
  • 진핵 세포에서 히스톤의 변형은 크로마틴 구조를 조절하는 데에 있어서 중요한 메커니즘이다. Set1 복합체에 의한 히스톤 H3의 네 번째 라이신 잔기(H3K4)에 발생하는 메틸화는 다양하게 잘 알려져 있는 히스톤 변형 중 하나이다. Set1 complex는 H2B의 유비퀴틴화에 의존적으로 발생하는 H3K4 메틸화에 중요하다고 알려진 Swd2를 포함하여 7개의 소단위 단백질을 가지고 있다. Swd2는 Set1의 RNA recognition motif (RRM) 도메인 근처에 결합하여 Set1의 활성을 조절하고, 또 RNA의 3' 말단 형성에 관여하는 CPF (Cleavage and Polyadenylation Factors) 복합체의 구성성분이라고 보고되었다. 최근 보고들에 따르면, 이런 Swd2의 이중적인 기능이 서로 독립적으로 작용하며, Swd2 결실돌연변이 균주가 살지 못하는 이유가 CPF 복합체의 구성성분으로써의 기능 때문이라고 알려져 있다. 본 연구에서 우리는 Swd2가 Set1의 RRM 도메인에 결합하여 Set1의 활성을 조절할 수 있을 뿐만 아니라, Set1의 안정성에도 영향을 줄 수 있음을 발견하였다. 또 우리는 Swd2가 결합할 수 없는 truncated-Set1을 가지고 있는 ${\Delta}swd2$ 돌연변이가 사멸하지 않고 정상적으로 자라는 것을 관찰하였다. 이런 결과들은 Saccharomyces cerevisiae에서 H3K4 메틸화와 RNA 3' 말단 형성과정에서의 Swd2의 이중적인 기능이 서로 독립적인 것이 아님을 제안하다.

MP2 Basis Set Limit Binding Energy Estimates of Hydrogen-bonded Complexes from Extrapolation-oriented Basis Sets

  • Park, Young-Choon;Lee, Jae-Shin
    • Bulletin of the Korean Chemical Society
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    • 제28권3호
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    • pp.386-390
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    • 2007
  • By use of a simple two-point extrapolation scheme estimating the correlation energies of the molecules along with the basis sets specifically targeted for extrapolation, we have shown that the MP2 basis set limit binding energies of large hydrogen-bonded complexes can be accurately predicted with relatively small amount of computational cost. The basis sets employed for computation and extrapolation consist of the smallest correlation consistent basis set cc-pVDZ and another basis set made of the cc-pVDZ set plus highest angular momentum polarization functions from the cc-pVTZ set, both of which were then augmented by diffuse functions centered on the heavy atoms except hydrogen in the complex. The correlation energy extrapolation formula takes the (X+1)-3 form with X corresponding to 2.0 for the cc-pVDZ set and 2.3 for the other basis set. The estimated MP2 basis set limit binding energies for water hexamer, hydrogen fluoride pentamer, alaninewater, phenol-water, and guanine-cytosine base pair complexes of nucleic acid by this method are 45.2(45.9), 36.1(37.5), 10.9(10.7), 7.1(6.9), and 27.6(27.7) kcal/mol, respectively, with the values in parentheses representing the reference basis set limit values. A comparison with the DFT results by B3LYP method clearly manifests the effectiveness and accuracy of this method in the study of large hydrogen-bonded complexes.

ON SET-VALUED MAPS AND HYPERSPACES

  • Kim, Rae-Seon;Lee, Eui-Chul
    • Journal of applied mathematics & informatics
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    • 제8권2호
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    • pp.635-640
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    • 2001
  • Let X be a T-admissible space and A(x) be the set of all admissible fibers at x∈X. In this paper, we introduce some basic concepts, properties, and known results about set-valued maps, hyperspaces and especially T-admissible spaces. And then, we construct a certain set-valued map(Theorem 2.3) and an arc from {x} to X∈A(x) in use of the set-valued maps(Theorem 2.3 through Theorem 2.7).

삼각벨트 클러치의 성능 향상에 관한 연구 (Performance Improvement of Triangular-type V-belt Clutch)

  • 신범수;김상헌;박희찬
    • Journal of Biosystems Engineering
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    • 제24권2호
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    • pp.99-106
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    • 1999
  • This study was conducted to provide a direction for improving the performance of triangular-type belt clutch. The power transmission characteristics and the wear of belt were investigated for two types of pulley set theoretically and experimentally. The results of research were summarized as follows: 1) Based on the theoretical analysis for the life time of belt, the wear of belt could be reduced by increasing the sizes of driving V-pulley and tension pulley, and by decreasing the tension on V-belt. 2) The pulley set # 2 could transmit more power than the pulley set # 1 could at the same slop rate. While the slip rate was 2.36% on the pulley set # 2 at the maximum power transmission, the slip rate on the pulley set # 1 was increased up to 12.2% at the same condition. 3) From the 16 hours' fatigue test, the wear of belt used n the pulley set # 1 was observed severer than that in the pulley set#2. Also, it was found that the tensile strength of belt used in the pulley set # 2 was greater than that of belt used in the pulley set # 1.

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Development of a Core Set of Korean Soybean Landraces [Glycine max(L.) Merr.]

  • Cho, Gyu-Taek;Yoon, Mun-Sup;Lee, Jeong-Ran;Baek, Hyung-Jin;Kang, Jung-Hoon;Kim, Tae-San;Paek, Nam-Chon
    • Journal of Crop Science and Biotechnology
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    • 제11권3호
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    • pp.157-162
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    • 2008
  • A total of 2,765 accessions were used as the initial set having both seed coat color and 100-seed weight data. As a result of molecular profiling using six SSR markers followed by stratification based on their usages, 335 accessions(12.1%) were selected by clustering based on UPGMA. Since 75 out of 335 accessions were mixed in phenotypic traits as a result of characterization, 260 accessions were finally set as a core set. This core set revealed nearly the same diversity compared with the other results on morphological traits of Korean soybean landraces. In total, 115 alleles(19.2 alleles per locus) were detected in the initial set and 79 alleles(13.2 alleles per locus) were detected in the core set. All 30 major alleles were present in the initial set and in the core set as well. In allele coverage, the core set was 71.4% of the initial set. These comparisons of number of alleles, gene diversity and coverage indicated that the core set represented the entire set well.

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SCORE SETS IN k-PARTITE TOURNAMENTS

  • Pirzada S.;Naikoo T.A.
    • Journal of applied mathematics & informatics
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    • 제22권1_2호
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    • pp.237-245
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    • 2006
  • The set S of distinct scores (outdegrees) of the vertices of a k-partite tournament T($X_l,\;X_2, ..., X_k$) is called its score set. In this paper, we prove that every set of n non-negative integers, except {0} and {0, 1}, is a score set of some 3-partite tournament. We also prove that every set of n non-negative integers is a score set of some k-partite tournament for every $n{\ge}k{\ge}2$.

AN EFFICIENT CONSTRUCTION OF PERIOD-2 BULBS IN THE CUBIC MANDELBROT SET WITH PARAMETRIC BOUNDARIES

  • Geum, Young-Hee;Kim, Young-Ik;Lee, Kang-Sup
    • Journal of applied mathematics & informatics
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    • 제25권1_2호
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    • pp.109-118
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    • 2007
  • A parametric boundary equation is established for the principal period-2 bulb in the cubic Mandelbrot set. Using its geometry, an efficient escape-time algorithm which reduces the construction time for the period-2 bulbs in the cubic Mandelbrot set is introduced and the implementation graphic results display the fascinating fractal beauty.

ROUGH STATISTICAL CONVERGENCE IN 2-NORMED SPACES

  • Arslan, Mukaddes;Dundar, Erdinc
    • 호남수학학술지
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    • 제43권3호
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    • pp.417-431
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    • 2021
  • In this study, we introduced the notions of rough statistical convergence and defined the set of rough statistical limit points of a sequence and obtained statistical convergence criteria associated with this set in 2-normed space. Then, we proved that this set is closed and convex in 2-normed space. Also, we examined the relations between the set of statistical cluster points and the set of rough statistical limit points of a sequence in 2-normed space.

Comparison of Number of Repetitions and Repetition Rate in 5 Sets of 65%1RM Bench Press and Biceps Curl Exercise

  • Kim, Ki Hong
    • International Journal of Internet, Broadcasting and Communication
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    • 제14권4호
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    • pp.163-172
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    • 2022
  • The purpose of this study is to investigate the changes in the number of repetitions and the repetition rate according to the exercise mode when performing 65%1RM resistance exercise at the 1-minute rest interval and the 3-minute rest interval. Sixteen healthy male subjects were treated with Bench press and Biceps curl of 65%1RM intensity at 1 and 3 minute rest intervals. The number of repetitions for each set of 1 minute rest interval showed a significant decrease from 1set to 5set in bench press. biceps curl showed a significant decrease from 1set to 4set. The repetition rate according to the exercise mode with a 1-minute rest interval showed a significant difference from 2sets to 4sets. In the repetition rate for each set, bench press showed a significant decrease from 1set to 5set. biceps curl showed a significant decrease from set 1 to set 4. The number of repetitions according to the exercise mode with a 3-minute rest interval showed a significant difference from 2sets to 5sets. In the number of repetitions for each set, bench press showed a significant decrease from 1set to 5set. biceps curl showed a significant decrease from 1set to 4set. The repetition rate according to the exercise mode with a 3-minute rest interval showed a significant difference from 2sets to 5sets. In the repetition rate for each set, bench press showed a significant decrease from 1 set to 5 sets. biceps curl showed a significant decrease from 1set to 4set. In summary, the decrease in the number of repetitions according to the set progression in the resistance exercise of the endurance depends on the exercise mode, and the increase of the rest interval or the decrease of the weight-intensity should be considered when aiming for more exercise.

Study on Safe Set and Maneuverability Envelope Protection during Arresting Landing

  • Liu, Zidong;Zhan, Hao;Wang, Shuang
    • International Journal of Aerospace System Engineering
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    • 제2권2호
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    • pp.73-78
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    • 2015
  • According to the characteristic of carrier-based aircraft, the method of solving safe set during arresting landing is discussed in this paper based on optimal control and invariant set theory. The safe sets of carrier aircraft are evaluated in different states on the characteristic of longitudinal augmented system by using the level set method. Then, the influence on the boundary of safe set under various factors is analyzed. At last, the maneuverability envelope protection is established based on the corresponding theory, and the validity of the system is verified through simulation. The results demonstrate preliminarily that: compared with mass and thrust, the elevator is the greatest influence factor for the boundary of safe set; the dynamic trajectory of carrier-based aircraft can be located at the interior of safe set effectively with the maneuverability envelope protection.