• Title/Summary/Keyword: Serum Biochemical Parameters

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INVESTIGATION OF EQUINE HEMATOLOGICAL CONSTITUENTS IN CENTRAL TAIWAN. I. DISTRIBUTION OF THE BLOOD CELL PARAMETERS AND THE BIOCHEMICAL COMPOSITIONS OF SERUM

  • Ju, J.C.;Cheng, S.P.;Fan, Y.K.;Hsu, J.C.;Chiang, S.K.;Chen, E.V.;Chang, S.H.;Chiou, S.C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.6 no.1
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    • pp.147-153
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    • 1993
  • A total of 109 heads of horses and ponies from eight horseback riding clubs nearby Central Taiwan were investigated to evaluate the blood parameters and the biochemical compositions of serum for the documentation of clinical pathological diagnosis and exercise physiology. Blood samples were collected from the jugular vein of resting horses. The sex difference in the blood traits were compared both in horses and in ponies. Results shows that total plasma proteins (PP) and hematocrit (PCV) were found higher in male horses than in females (p < 0.05). The sexual effect also exertes a significant influence on the leucocyte (WBC) count, but not on the erythrocyte (RBC) concentration. According to the differential counts of leucocytes, the number of monocytes and lymphocytes was higher in the male pony than that of in male horse. A close relationship Between the erythrocyte sedimention rate (ESR) and the other blood parameters were found especially in PCV, RBC concentration, and plasma protein level. The average ESR observed at 60 minutes were $21.80{\pm}21.87mm$, $39.50{\pm}18.90mm$ and $43.73{\pm}17.89mm$ in stallions, geldings, and mares, respectively. Most of the biochemical components of horse serum detected were distributed in normal ranges, although some of the items show a great variation in such a large sample size.

Effect of fermented biogas residue on growth performance, serum biochemical parameters, and meat quality in pigs

  • Xu, Xiang;Li, Lv-mu;Li, Bin;Guo, Wen-jie;Ding, Xiao-ling;Xu, Fa-zhi
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.10
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    • pp.1464-1470
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    • 2017
  • Objective: This study investigated the effect of fermented biogas residue (FBR) of wheat on the performance, serum biochemical parameters, and meat quality in pigs. Methods: We selected 128 pigs (the mean initial body weight was $40.24{\pm}3.08kg$) and randomly allocated them to 4 groups (1 control group and 3 treatment groups) with 4 replicates per group and 8 pigs per pen in a randomized complete block design based on initial body weight and sex. The control group received a corn-soybean meal-based diet, the treatment group fed diets containing 5%, 10%, and 15% FBR, respectively (abbreviated as FBR5, FBR10, and FBR15, respectively). Every group received equivalent-energy and nitrogen diets. The test lasted 60 days and was divided into early and late stages. Blood and carcass samples were obtained on 60 d. Meat quality was collected from two pigs per pen. Results: During the late stage, the average daily feed intake and average daily gain of the treatment groups was greater than that of the control group (p<0.05). During the entire experiment, the average daily gain of the treatment groups was higher than that of the control group (p<0.05). Fermented biomass residue did not significantly affect serum biochemical parameters or meat quality, but did affect amino acid profiles in pork. The contents of Asp, Arg, Tyr, Phe, Leu, Thr, Ser, Lys, Pro, Ala, essential amino acids, non-essential amino acids, and total amino acids in pork of FBR5 and FBR10 were greater than those of the control group (p<0.05). Conclusion: These combined results suggest that feeding FBR could increase the average daily gain and average daily feed intake in pigs and the content of several flavor-promoting amino acids.

Cordycepin from Medicinal Fungi Cordyceps militaris Mitigates Inflammaging-Associated Testicular Damage via Regulating NF-κB/MAPKs Signaling in Naturally Aged Rats

  • Kopalli, Spandana Rajendra;Cha, Kyu-Min;Cho, Jae Youl;Kim, Si-Kwan;Koppula, Sushruta
    • Mycobiology
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    • v.50 no.1
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    • pp.86-95
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    • 2022
  • Inflammaging in male reproductive organs covers a wide variety of problems, including sexual dysfunction and infertility. In this study, the beneficial effects of cordycepin (COR), isolated from potential medicinal fungi Cordyceps militaris, in aging-associated testicular inflammation and serum biochemical changes in naturally aged rats were investigated. Male Sprague Dawley rats were divided into young control (YC), aged control (AC), and COR (5, 10, and 20 mg/kg) treated aged rat groups. Aging-associated serum biochemical changes and inflammatory parameters were analyzed by biochemical assay kits, Western blotting, and real-time RT-PCR. Results showed a significant (p < 0.05) alteration in the total blood cell count, lipid metabolism, and liver functional parameters in AC group when compared with YC group. However, COR-treated aged rats ameliorated the altered biochemical parameters significantly (p < 0.05 and p < 0.01 at 5, 10, and 20 mg/kg, respectively). Furthermore, the increase in the expression of inflammatory mediators (COX-2, interleukin (IL)-6, IL-1β, and tissue necrosis factor-alpha) in aged rat testis was significant (p < 0.05) when compared with YC group. Treatment with COR at 20 mg/kg to aged rats attenuated the increased expression of inflammatory mediators significantly (p < 0.05). Mechanistic studies revealed that the potential attenuating effects exhibited by COR in aged rats was mediated by regulation of NF-κB activation and MAPKs (c-Jun N-terminal kinase, extracellular signal-regulated kinase 1/2, and p38) signaling. In conclusion, COR restored the altered serum biochemical parameters in aged rats and ameliorated the aging-associated testicular inflammation proving the therapeutic benefits of COR targeting inflammaging-associated male sexual dysfunctions.

Protective Effects of Angelica koreana on Experimentally Induced Liver Injury (실험적 간장해에 대한 강활의 보호효과)

  • Yoon Soo Hong;Ha Hun
    • Environmental Analysis Health and Toxicology
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    • v.20 no.2 s.49
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    • pp.161-165
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    • 2005
  • The present study was carried out to find the possible protective effects of Angelica koreana water extract on biochemical parameters in benzo(a)pyrene (B(a)P)-induced liver injury in rats. B(a)P treatment (0.1 mg/kg, 1.p.) caused a liver damages, which led to biochemical alterations in serum and liver enzyme activities and serum lipid levels. The activities of liver marker enzymes, especially, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH) were markedly changed in B(a)P treatment. Oral administration of Angelica koreana (50 mg/kg) recovered these biochemical Parameters to near normal levels. Therefore, the present results have revealed that Angelica koreana water extract might have the antihepatotoxic effect and consequently ameliorate liver damage associated with B(a)P in rats.

Risk assessment of Nitrogen Dioxide exposure on Welders

  • Jeong Seong-Wook;Song Seung-Hyg;Park Heung-Jai
    • Journal of Environmental Science International
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    • v.14 no.1
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    • pp.9-14
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    • 2005
  • This study evaluated the hazard caused by $NO_{2}$, an oxidant generated in the process of welding. We com­pared hematological and biochemical parameters in workers who chronically inhale $NO_{2}$ and office workers not exposed to $NO_{2}$. $NO_{2}$ exposure affected the hematological and biochemical parameters. Increasing $NO_{2}$ concen­trationincreased the number of leukocytes, while decreasing the number of erythrocytes. Blood urea nitrogen, cre­atinine, uric acid, and lactate dehydrogenase were increased, while total protein and triglycerides were decreased. The mean concentration of $NO_{x}(NO_{2}^{-}/NO_{3}^{-})$ in the serum of welders and the control group was $35.97{\pm}2.85\;and\;55.40{\pm}5.81\;{\mu}mol/L,$ respectively. The difference was significant (p < 0.05), although $NO_{2}^{-}$ was not detected in the serum.

Effects of Dietary Electrolyte Balance on Growth Performance, Nitrogen Metabolism and Some Blood Biochemical Parameters of Growing Rabbits

  • Li, J.W.;Wang, X.P.;Wang, C.Y.;Zhu, Y.L.;Li, F.C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.12
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    • pp.1726-1731
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    • 2013
  • The effects of different dietary electrolyte balance (DEB) on growth performance, nitrogen (N) metabolism and some blood biochemical parameters were investigated in 2 to 3 months old growing rabbits. A total of 150 growing rabbits of 2 months age were randomly divided into five groups according to average body weight, with 30 rabbits in each group. The DEB levels of the five experimental diets were -154, -3.16, +201, +347, and +500 meq/kg of dry matter (DM), respectively. There was a 7-d adaptation period and a 23-d experimental period. The results showed that the DEB levels had a quadratic affect on the average daily feed intake (ADFI) (p<0.001). The greatest ADFI was achieved when the DEB level was +201 meq/kg DM. Fecal N (FN) content linearly decreased (0.047), while digestible N (DN), retained N (RN), efficiency of intake N converted into digestible N (DN/IN) and the efficiency of intake N converted into retained N (RN/IN) linearly increased with the DEB increase (0.020, 0.004, 0.021, and 0.049, respectively). Serum phosphorus (P) ion content linearly increased with the DEB increase (p = 0.036). The DEB had a quadratic relationship with serum anion gap (AG) (p = 0.002) and serum parathyroid hormone (PTH) content (p = 0.016). The DEB levels quadratically affected base excess (BE) in the plasma (p<0.001). In conclusion, the DEB unaffected growth performance but affected feed intake, N metabolism and some blood biochemical parameters of growing rabbits.

Effects of induced heat stress on temperature response and biochemistry: alteration of biochemical constituents in Holstein calves by heat stress

  • Lim, Hyun-Joo;Ki, Kwang-Seok
    • Korean Journal of Agricultural Science
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    • v.46 no.3
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    • pp.637-643
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    • 2019
  • The aim of the present study was to evaluate the effect of the induced heat stress on physiological response and serum biochemical parameters involving glucose, cholesterol, blood urea nitrogen (BUN), non-esterified fatty acids (NEFA), and cortisol in Holstein calves. Ten calves were kept in a climate controlled room (air temperature $37^{\circ}C$ and 90% humidity from 09:00 to 19:00) for three days. Those animals were given a one-day adaptation period. During the treatment period, we measured the skin temperature six times. Following the treatment periods, blood samples were collected before the experiment began (09:00) and at the end of the stress period (19:00). To aid analysis of the biochemical parameters, also we monitored the rectal temperature. The results, exhibited that both rectal and skin temperature showed increase in the heat stress-induced animals as compared with unstressed animals. Moreover, we noticed that the levels of BUN and NEFA increased in the blood serum of heat stress induced animals when compared with un-stressed ones. From these results, we concluded that the physiological and biochemical changes in the calves were induced by heat stress. Hence, the present study findings could be employed as base line data for development of stress reduction techniques in the dairy industry.

Effect of Partial Substitution of Dietary Spray-dried Porcine Plasma or Fishmeal with Soybean and Shrimp Protein Hydrolysate on Growth Performance, Nutrient Digestibility and Serum Biochemical Parameters of Weanling Piglets

  • Sun, Zhantian;Ma, Qiugang;Li, Zhongrong;Ji, Cheng
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.7
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    • pp.1032-1037
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    • 2009
  • The present experiment was conducted to study the effects of partial replacement of spray-dried porcine protein (SDPP) or fish meal with soybean and shrimp protein hydrolysate (SSPH) on growth performance, nutrient digestibility and serum biochemical parameters in weaned pigs. Two hundred and forty 21${\pm}$2 d old pigs ((Pietrain${\times}$Duroc)${\times}$(Landrace${\times}$Large Yorkshire)) with initial weight of 6.9${\pm}$0.5 kg were randomly allocated to five dietary treatments with six replicates per treatment and eight piglets per replicate. The control diet (T1) contained 2% SDPP and 6% fishmeal, and SDPP for experimental diets T2 and T3 was replaced with 1% and 2% SSPH, respectively, on an iso-nitrogenous basis. The fishmeal for experimental diets T4 and T5 was replaced with 1% and 2% SSPH, respectively, also on an iso-nitrogenous basis. The experimental period was 21 days. The results showed that weaned piglets fed the diets containing 1% and 2% SSPH as a replacement for SDPP had similar average daily gain (ADG), average daily feed intake (ADFI), feed/gain (F/G), diarrhea rate and serum biochemical indices e.g. blood urea nitrogen (BUN), total serum protein (TP), albumin to globulin ratio (A/G), globulin (GLO), serum glucose (GLU), and immunoglobulin G (IgG) to those fed the control diet during 0-10 d and 0-21 d of the experiment. The substitution of 1% SSPH on an iso-nitrogenous basis for fish meal appeared to be beneficial for ADG (p = 0.59) and ADFI (p = 0.23) of piglets during the overall period. The digestibility of calcium was higher (p<0.01) in pigs fed diets containing SSPH than on the control diet. Addition of 1% SSPH on an iso-nitrogenous basis for fish meal could increase the digestibilities of dry matter and energy of the diet. Dietary replacement of fish meal with 1% and 2% SSPH had no effect on the concentrations of BUN, TP, A/G, GLO, GLU, and IgG. In conclusion, dietary SDPP or fish meal could partially replace SSPH without any adverse effect on growth performance, nutrient digestibility and serum biochemical parameters in weaned piglets.

Significance of varying concentrations of T-2 toxin on growth performance, serum biochemical and hematological parameters in broiler chickens

  • Singh, Ram;Park, Sungkwon;Koo, Jin Su;Kim, In Ho;Balasubramanian, Balamuralikrishnan
    • Journal of Animal Science and Technology
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    • v.62 no.4
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    • pp.468-474
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    • 2020
  • The study was to determine the effects of diverse concentrations of T-2 toxin in broiler diet. Three hundred 1-day-old chicks with initial body weight of 46 ± 0.52 g were chosen and randomly assigned into five dietary treatments with 5 replicate cages and 12 broilers per cage for 42 d feeding trial. Dietary treatments were prepared with basal diets containing 0 (T1), 50 (T2), 100 (T3), 150 (T4), 200 (T5) ppb T2-toxin. Significant results were observed in the decreased intake of feed, feed conversion ratio (FCR), body weight gain (BWG), level of serum protein, cholesterol and hemoglobulin of broilers in increased concentration of the T-2 toxin in diet (150 and 200 ppb) groups than control. Also, observed that the uric acid, serum glutamic pyruvic transferase (SGPT), serum glutamic oxaloacetic transferase (SGOT) and Heterophil/Lymphocyte (H/L) ratio value were significantly higher (p < 0.05) in groups T4 and T5 than control. However, the BWG, feed intake and FCR, as well blood biochemical profiles of serum protein, cholesterol, hemoglobulin, uric acid, SGPT, SGOT and H/L ratio in groups T2 and T3 were statistically similar to control diet of broilers. It was concluded that the results showed that no adverse effects on growth performance and blood biochemical parameters in broilers feed with T-2 toxin (50 and 100 ppb) during the entire trial.

A Study on Nutritional Status, Biochemical Parameters, Lipid and Electrolytes Concentrations According to the Duration of Enteral Nutrition Tube-feeding (경장영양 기간에 따른 영양상태, 생화학적 지표, 지질 및 전해질 농도에 관한 연구)

  • 이정화;조금호;이봉암;이선화;조여원
    • Journal of Nutrition and Health
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    • v.35 no.5
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    • pp.512-523
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    • 2002
  • The objective of this study was to investigate the nutritional status, biochemical parameters, lipid and electrolytes concentrations of the enteral nutrition patients according to the duration of enteral nutrition. Eighteen neurosurgery patients in the intensive care unit (ICU) at K University Hospital were subjected in this study. The duration of enteral nutrition was classified into under or over six month of period. Anthropometric, biochemical, clinical, and dietary assessments were performed. Patients' intakes of energy and protein were insufficient, from 82% to 95% of their requirements. Mid-arm muscle circumference (MAMC) and mid-am muscle area (MAMA) were significantly lower in patients over six months of enteral nutrition than those in patients under six months. The subjects were malnourished as indicated by nutrition-related parameters such as hemoglobin, albumin, total lymphocyte count (TLC), tricep skinfold thickness (TSF), mid-arm circumference (MAC), MAMC, and MAMA. Serum chloride level of the patients eve, six months of enteral nutrition was lower (94.7 $\pm$ 3.4 mmo1/1) significantly as compared to that of patients (99.3 $\pm$ 3.5 mmol/ 1) under six months. Urinary sodium and chloride levels were lower in the longer time of enteral nutrition patients than those of shorter period of enteral nutrition patients (p < .05). While serum phospholipid level was higher in the patients over six months of enteral nutrition, other blood biochemical parameters and electrolyte concentrations did not show any differences with the duration of enteral nutrition. Neurosurgery patients in the ICU undergoing long-term enteral nutrition tube-feeding were malnourished and had a variety of metabolic complications. The duration of enteral nutrition could affect the patients' nutritional status, biochemical parameters, and electrolytes balance. The patients who require nutritional support over an extended time need the continuous follow-up care and monitoring by the nutrition support team for laboratory, clinical, and nutritional assessments.