• Molecules and Cells
• /
• v.45 no.1
• /
• pp.6-15
• /
• 2022

Phase separation is a thermodynamic process leading to the formation of compositionally distinct phases. For the past few years, numerous works have shown that biomolecular phase separation serves as biogenesis mechanisms of diverse intracellular condensates, and aberrant phase transitions are associated with disease states such as neurodegenerative diseases and cancers. Condensates exhibit rich phase behaviors including multiphase internal structuring, noise buffering, and compositional tunability. Recent studies have begun to uncover how a network of intermolecular interactions can give rise to various biophysical features of condensates. Here, we review phase behaviors of biomolecules, particularly with regard to regular solution models of binary and ternary mixtures. We discuss how these theoretical frameworks explain many aspects of the assembly, composition, and miscibility of diverse biomolecular phases, and highlight how a model-based approach can help elucidate the detailed thermodynamic principle for multicomponent intracellular phase separation.

• Journal of the Korean Society of Propulsion Engineers
• /
• v.20 no.2
• /
• pp.67-74
• /
• 2016

Explosive bolt is one of separation device that uses high explosive charge, and is separated by pressure formed by an explosion and the resulting shock waves. Explosive bolt having such a mechanism would have to be designed to minimize shock and debris formation generated during separation. In this study, separation tests were carried out with distance as variable for restraining the explosive bolt (Air Gap). Bolt release and its separating shape with variation of air gap is observed, and we used accelerometer to measure the shock wave transmitted through a bound object. In addition, separation behavior of explosive bolt is analyzed using ANSYS AUOTODYN program. By comparing the results of previously performed experiments and analysis, we could confirm the effects of air gap to the release behavior of explosive bolt, and decide optimum constraining environment for specific separation bolts.

• Corrosion Science and Technology
• /
• v.8 no.3
• /
• pp.103-109
• /
• 2009

An epoxy coating was designed to give a hydrophobic property on its surface by modifying it with three types of Amino Terminated Polydimethylsiloxane (ATP), and then effects of the modification on the structure, surface hydrophobic tendency, water transport behavior and hence corrosion protectiveness of the modified epoxy coating were examined using FT-IR spectroscopy, hydrothermal cyclic test, and impedance test. The surface of epoxy coating was changed from hydrophilic to hydrophobic property due primarily to a phase separation tendency between epoxy and modifier by the modification. The phase separation tendency is more appreciable when modified by ATP with higher molecular weight ATP at higher content. Water transport behavior of the modified epoxy coating decreased more in that with higher hydrophobic surface property. The resistance to localized corrosion of the modified epoxy coated carbon steel was well agreed with its water transport behavior and hydrophobic tendency.

• Proceedings of the Korea Concrete Institute Conference
• /
• 2004.11a
• /
• pp.105-108
• /
• 2004

In general, the nonlinear behavior of composite structures composing of steel and concrete is analyzed on the basis of the assumption of the perfect bond actions in steel-concrete interface in which the interface slip or separation is not allowed. The assumption is based on the fact that the full interface bond behavior is provided with the mechanical connectors of studs. However, since the number and spacing of the studs are determined by the stress resultants calculated in the interface area, the interface analysis is required to evaluate the stress resultants. This paper describes the nonlinear steel-concrete interface behavior considering the two interface failure mechanisms of slip and separation. Elastoplastic constitutive relation is developed. thru the formulation framework using the two energy dissipation mechanisms. As the result, the steel plate push-out tests sandwitched between concrete blocks are analyzed and compared with the test results with which the good agreements are observed.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.40 no.5
• /
• pp.879-893
• /
• 2016

This study explores the determinants of clothing disposition and examines their effect on the dimensions of clothing disposition behavior. The data of 316 women were collected nationwide using an online self-administered questionnaire. This study initially identified five types of disposition behavior as revising, permanent separation, giving away, selling, and donating to charity. Exploratory and confirmative factor analysis identified the underlying determinants of clothing disposition as self-concept, reusability, economic factor, social environment, affective association, storage, fashionableness, and a sense of belongingness. Structural equation modeling was conducted to examine the relationships between variables. The results demonstrated that six out of eight determinants significantly affected clothing disposition behavior. The effects of social environment and a sense of belongingness were relatively strong determinants that influenced the four types of disposition behaviors. However, self-concept and affective association did not influence the disposition behaviors. A series of one-way MANOVA was conducted to determine the effect of the eight demographic variables on the four modes of clothing disposition. Giving away, permanent separation, and donating to charity differed significantly in the groups of three demographic variables such as age, monthly income, and marital status. This study empirically elucidates what criteria consumers use when confronted with unused clothing and how the determinants of clothing disposition influence the modes of clothing disposition behavior. This study provides a framework for clothing disposition behavior and its determinants as well as suggests a new approach to clothing disposition behavior and improvements in marketing decisions.

• Proceedings of the Korean Fiber Society Conference
• /
• 1990.06a
• /
• pp.25-26
• /
• 1990

• Korean Chemical Engineering Research
• /
• v.54 no.1
• /
• pp.57-63
• /
• 2016

Thermally induced phase separation (TIPS) and nonsolvent induced phase separation (NIPS) were simultaneously induced for the preparation of flat PVDF membranes. N-methyl-2-pyrrolidone (NMP) was used as a solvent and dibutyl-phthlate (DBP) was used as a diluent for PVDF. When PVDF was melt blended with NMP and DBP, crystallization temperature was lowered for TIPS and unstable region was expanded for NIPS. Ratio of solvent to diluent changed the phase separation mechanism to obtain the various membrane structures. Contact mode of dope solution with nonsolvent determined the dominant phase separation behavior. Since heat transfer rate was greater than mass transfer rate, surface structure was formed by NIPS and inner structure was by TIPS. Quenching temperature of dope solution also affected the phase separation mechanism and phase separation rate to result in the variation of structure.

• Korean Chemical Engineering Research
• /
• v.54 no.1
• /
• pp.89-93
• /
• 2016

In this study, we investigated the separation behavior of the anticancer agent paclitaxel and its semi-synthetic precursor 10-deacetylpaclitaxel (10-DAP) from plant cell cultures. As a result of sequential separation/purification performed by biomass extraction with solvent, liquid-liquid extraction, adsorbent treatment, hexane precipitation, and fractional precipitation, the adsorbent treatment was found to be the most effective in separating and recovering 10-DAP from paclitaxel. The optimal adsorbent type, crude extract/adsorbent ratio, and adsorbent treatment temperature were sylopute, 1:1.5 (w/w), and $20^{\circ}C$, respectively. The separation/recovery of 10-DAP from paclitaxel was 74.1% in adsorbent treatment process under optimal conditions.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.46 no.12
• /
• pp.1004-1011
• /
• 2018

Recently, pyrotechnic separation nut has attracted a considerable attention because of its shock reduction effect among various pyrotechnic mechanical devices. However, its bolt loosening behavior under transverse vibration has not been studied sufficiently, since segmented nuts are utilized instead of conventional nut in pyrotechnic separation nut. With the background, bolt loosening analyses are carried out referring to Junker vibration test. The analysis procedure consists of two steps. The first step is the bolt fastening step, screwing the bolt by fastening torque. The second step is the bolt loosening step under transverse vibration. Through the procedure, bolt loosening behaviors are obtained, and the effect of clearance on loosening behavior is closely investigated for reliable design of pyrotechnic separation nut.

• Korean Journal of Materials Research
• /
• v.29 no.11
• /
• pp.703-708
• /
• 2019

In this study, we investigate the relationship between the peeling behavior of the backsheet of a photovoltaic(PV) module and its surface temperature in order facilitate removal of the backsheet from the PV module. At low temperatures, the backsheet does not peel off whereas, at high temperatures, part of the backsheet remains on the surface of the PV module after the peeling process. The backsheet material remaining on the surface of the PV module is confirmed by X-ray diffraction(XRD) analysis to be poly-ethylene(PE). Differential scanning calorimetry(DSC) is also performed to investigate the interfacial characteristics of the layers of the PV module. In particular, DSC provides the melting temperature($T_m$) of laminated ethylene vinyl acetate(EVA) and of the backsheet on the PV module. It is found that the backsheet does not peel off below the $T_m$ of ethylene of EVA, while the PE layer of the backsheet remains on the surface of the PV module above the $T_m$ of the PE. Thus, the backsheet is best removed at a temperature between the $T_m$ of ethylene and that of PE layer.