• 가정과삶의질연구
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• 제29권6호
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• pp.9-25
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• 2011

This study was performed to explore the factors that affect debt-use intention of young defaulters. In addition, this study compares three models that predict the intention to use debt by young defaulters: the theory of reasoned action and two variations of it. Specifically, this study proposes an extended theory of reasoned action by introducing Ao in place of the cognitive structure in the theory of reasoned action. In addition, this study proposes Ao as an independent variable that acts on BI rather than a dependent variable. Self-administered questionnaires were completed by 196 young defaulters attending a credit management education session held by the Credit Counseling & Recovery Service in Kwang-ju, Korea. Based on the study, the conclusions are as follows: the extended theory of reasoned action as proposed in this article most suitably explained the intention to use debt by young defaulters. It was also found that young defaulters were affected by attitudes toward debt, attitudes toward using debt, and subjective norms. It is therefore suggested that an attitudinal message would change the behavior effectively for young defaulters. The findings appeared to support the usefulness of the extended theory of reasoned action and the role of Ao as an independent variable as proposed in this article to explain the intention to use debt by young defaulters. These findings have an important theoretical meaning in that they modify two existing attitude theories in the context of consumer behavior.

• 대한한방부인과학회지
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• 제25권2호
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• pp.207-214
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• 2012

Objectives: The most common symptom of adenomyosis is dysmenorrhea and menorrhagia. Therefore, final treatment of this disease is hysterectomy. If dysmenorrhea and menorrhagia can be controlled, It doesn't need the surgical treatment. so, this case study was designed to evaluate the effect of Gamiseokhong-jeon on dysmenorrhea, menorrhagia due to adenomyosis. Methods: A 45-year-old female patient who was diagnosed with adenomyosis has been troubled by dysmenorrhea and menorrhagia. She was taken Korean herbal medicine(Gamiseokhong-jeon gamibang) about 3 months. Results: During this treatment period, dysmenorrhea and menorrhagia were relieved. Also after all treatment, the effect has been continuing. Conclusions: Gamiseokhong-jeon gamibang relieve dysmenorrhea and menorrhagia due to adenomyosis.

• 농업과학연구
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• 제46권3호
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• pp.591-599
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• 2019

The study was conducted to investigate the growth performance of two strains of Korean domestic chickens (KDC, i.e., 1A, and 2A). A total of 600, one-day-old female chicks were allocated in a completely randomized design to give 15 replicates for each strain (10 birds per pen). The chickens were fed (week 0 to 6: ad libitum; week 6 to 12: restricted feeding) commercial diets (week 0 to 5: crude protein 20.3% and metabolizable energy 3,059 kcal/kg; week 5 to 8: crude protein 18.6% and metabolizable energy 3,123 kcal/kg, and week 8 to 12: crude protein 16.7% and metabolizable energy 3,187 kcal/kg) together with fresh water. Body weight (BW) and feed intake were measured bi-weekly to calculate the average daily feed intake (ADFI), average daily gain (ADG), and subsequently the feed conversion ratio (FCR). The results indicate that the 1A crossbreed had a higher (p < 0.05) BW compared to the 2A crossbreed from week 6 to 10. A higher ADG (p < 0.05) was seen in the 1A crossbreed on week 6 and in the 2A crossbreed on week 8. Moreover, no difference (p > 0.05) was observed in the FCR between crossbreed 1A and 2A during the 12 weeks with the exception of week 8. Crossbreed 1A had (p < 0.05) an improved FCR compared to the 2A crossbreed on week 8. In conclusion, the 1A crossbreed had a higher growth performance compared to the 2A crossbreed for 12 weeks after hatching. This data can contribute by helping the KDC market.

• Molecules and Cells
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• 제44권7호
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• pp.458-467
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• 2021

GPR43 (also known as FFAR2 or FFA2) is a G-protein-coupled receptor primarily expressed in immune cells, enteroendocrine cells and adipocytes that recognizes short-chain fatty acids, such as acetate, propionate, and butyrate, likely to be implicated in innate immunity and host energy homeostasis. Activated GPR43 suppresses the cAMP level and induces Ca²⁺ flux via coupling to Gα_i and Gα_q families, respectively. Additionally, GPR43 is reported to facilitate phosphorylation of ERK through G-protein-dependent pathways and interacts with β-arrestin 2 to inhibit NF-κB signaling. However, other G-protein-dependent and independent signaling pathways involving GPR43 remain to be established. Here, we have demonstrated that GPR43 augments Rho GTPase signaling. Acetate and a synthetic agonist effectively activated RhoA and stabilized YAP/TAZ transcriptional coactivators through interactions of GPR43 with Gα_q/11 and Gα_12/13. Acetate-induced nuclear accumulation of YAP was blocked by a GPR43-specific inverse agonist. The target genes induced by YAP/TAZ were further regulated by GPR43. Moreover, in THP-1-derived M1-like macrophage cells, the Rho-YAP/TAZ pathway was activated by acetate and a synthetic agonist. Our collective findings suggest that GPR43 acts as a mediator of the Rho-YAP/TAZ pathway.

• PNF and Movement
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• 제21권2호
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• pp.151-158
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• 2023

Purpose: This study aimed to examine the immediate effects of different breathing training techniques on diaphragm excursion and vital capacity in healthy adults. Specifically, the study focused on comparing respiratory exercise without PNF, bilateral pattern respiratory exercise, and bilateral pattern with spiral pattern respiratory exercise. Methods: Twenty-seven healthy adults in their 20s participated in the study. Diaphragm excursion and vital capacity were evaluated under three different conditions. A one-way repeated ANOVA was used to analyze the differences in diaphragm excursion and vital capacity among the interventions. Results: Statistically significant differences were observed in diaphragm excursion among the interventions, comparing respiratory exercise without PNF, bilateral pattern respiratory exercise, and bilateral pattern with spiral pattern respiratory exercise. Similarly, statistically significant differences were found in vital capacity among the interventions without PNF respiratory exercise, bilateral pattern respiratory exercise, and bilateral pattern with spiral pattern respiratory exercise. Conclusion: The study demonstrated that incorporating the spiral technique in respiratory exercise led to increased diaphragm excursion and lung capacity compared to other interventions. These findings suggest that PNF respiratory exercise combined with the spiral pattern may have clinical implications for the treatment of respiratory diseases. Further research is warranted to explore the long-term effects and clinical application of these approaches.

• 우울조울병
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• 제9권2호
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• pp.57-63
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• 2011

Objectives : This study aimed to investigate the prevalence and risk factors of depression within two weeks after stroke. Methods : A total of 362 stroke patients were recruited. Depression (major and minor depressive disorders) was diagnosed by applying DSM-IV criteria. Data on socio-demographic characteristics (age, gender, education, marital state, living state, religion, occupation, income, life event, and social support), stroke severity (NIHSS), disability (BI), stroke hemisphere and location, vascular risk and disease, and previous history of stroke and depression were obtained. Results : Depression was present in 90 (24.9%) patients: major depression 29 (8%) and minor depression 61 (16.9%) patients. In the univariate analyses, depression was associated with older age, higher number of stressful life event, poorer social support, severe disability, anterior stroke location, previous history of stroke and depression. In the multivariate analyses, depression was independently associated with higher number of stressful life events and poorer social support. Conclusion : Depression was common and was determined by premorbid levels of stress and social support in stroke patients at acute stage. More intensive psychiatric care and intervention is needed for the high risk group.

• 자원환경지질
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• 제19권3호
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• pp.199-218
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• 1986

울산(蔚山)의 철 중석 스카른광상에서 산출되는 유비철석(硫砒鐵石)은 그의 산출상태(産出狀態) 광물공생관계(鑛物共生關係) 화학조성(化學組成)을 근거로 세 가지 유형으로 구분된다. 유비철석(硫砒鐵石) I 은 다금속광화작용(多金屬鑛化作用) 초기에 정출된 것으로 주로 스카른대 내에서 산점상으로 분포하며, Ni-Fe-Co계 유화물과 밀접한 공생관계를 보여준다. 유비철석(硫砒鐵石) I 의 화학조성은 Ni, Co의 함량이 현저하게 높고 As/S(원자비(原子比))>1으로 과잉(過剩)의 비소를 함유한다. 유비철석(硫砒鐵石) II는 Cu 또는 As 광석중에서 산출되며, 비독사석 휘창연석 비스무스 황동석 섬아연석과 밀접한 공생관계를 보여준다. 유비철석(硫砒鐵石) II의 화학조성은 Ni, Co의 함량이 극히 미량이며, As/S>1으로 과잉(過剩)의 비소를 함유한다. 유비철석(硫砒鐵石) III은 최후기 열수광맥 형성시기에 정출되었으며, 황철석 방연석 섬아연석 자류철석과 밀접한 공생관계(共生關係)를 보여준다. 유비철석(硫砒鐵石) III의 화학조성(化學組成)은 $$As/S1{\leq_-}1$$로 과잉(過剩)의 S를 함유한다. 유비철석(硫砒鐵石) I 은 Ni, Co의 함유량이 1%이상이므로 지질온도계(地質溫度計)로 사용할 수 없지만, 유비철석(硫砒鐵石) II 는 비스무스-휘창연석의 공생관계(共生關係)를 보여 주고 있으므로, 이를 Kretschmar and Scott (1976)에 의한 $1/T-f(S_2)$도에 적용시켜보면 유비철석(硫砒鐵石) II의 정출환경은 $T=460{\sim}470^{\circ}C$, log $f(S_2)=-7.4{\sim}7.0$이고, 유비철석(硫砒鐵石) III의 정출환경은 $T=320{\sim}440^{\circ}C$, log $f(S_2)=-9.0{\sim}7.0$으로 추정된다.

• 대한영상의학회지
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• 제83권5호
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• pp.1090-1103
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• 2022

목적 본 연구는 미세석회화가 의심되는 유방에서 정위적 조직검사에 앞서서 시행하는 디지털 유방단층영상합성법(digital breast tomosynthesis with the two-dimensional synthesized mammogram; 이하 DBT with 2DSM)과 전면디지털유방촬영술(full-field digital mammography; 이하 FFDM)의 진단능을 비교 평가하고 영상의 진단적 명확도를 평가하기 위해서 시행하였다 대상과 방법 2015년 1월에서 2020년 1월까지 후향적 연구로서 189명의 환자 중 정위적 조직검사를 통한 조직병리검사상 미세석회화 병변이 확인된 환자를 중 DBT with 2DSM나 FFDM을 시행한 환자군에서 시행되었다. 두 명의 영상의학과 의사가 눈가림 상태로, Breast Imaging Reporting and Data System (BI-RADS) 분류에 따른 미세석회화의 평가 및 본 연구에서 별도로 1-5점 척도를 통해 정의한 진단적 명확도에 대한 평가를 시행하였다. 결과 전반적인 검사자간 일치도는 우수한 것으로 확인되었다. 맥네머 검정에서 악성가능성이 높은 미세석회화(4B, 4C, or 5)의 검출에 있어서는 두 진단방법 간에 통계적 유의성은 보이지 않았으나, 양성가능성이 높은 미세석회화(4A)의 진단에 있어서는 통계적 유의성을 보였다. DBT with 2DSM는 FFDM보다 더 높은 가시성을 보임이 확인되었고, 치밀유방에서도 FFDM보다 진단에 있어서 더 우수하였다. 결론 DBT with 2DSM는 FFDM과 비교하여 미세석회화 병변에 대해서 더 높은 전반적 진단적 정확도와 진단적 명확성을 제공하였다. DBT with 2DSM는 FFDM보다 양성 미세석회화 병변에서와 치밀유방에서 우수성을 보였다. 본 연구에서는 치밀 유방에서 미세석회화 병변에 대해서 정위적 생검을 시행할 때 유용한 진단 기구로서의 DBT with 2DSM의 역할을 확인할 수 있었다.

• 한국식품위생안전성학회지
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• 제20권1호
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• pp.53-57
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• 2005

지하 943 m(3호공)로부터 취수한 경산 광천수의 유$\cdot$무기성분을 분석한 결과 총 17종류의 성분 중 무기물은 11 종류가 검출되었으며 무기성분 중에서는 나트륨과 칼슘 성분이 많이 함유되어 있는 것이 특징이었다. 그리고 구리와 납과 같은 중금속과 탄산가스 및 유화수소는 검출되지 않았다. 그리고 항산화 활성, 항돌연변이원성 및 인간암세포 성장억제 실험 결과 항산화 활성에서는 비교적 약한 활성을 나타내었다. MNNG, 4NQO, Trp-P-1및 $B({\alpha})P$와 같은 돌연변이원을 이용한 미생물 수준에서의 항돌연변이원성 실험 결과 S. typhimurium TA98에 대해서 간접변이원인 Trp-P-1은 시료 농도 $200{\mu}g/plate$ 첨가 시 $54\%$의 억제 활성을 나타내었다. 또한 S. typhimurium TA100 균주에서 4NQO 및 MNNG는 각각 $65.8\%$ 와 $58.6\%$의 억제활성을 보였으며 $B({\alpha})P$ 및 Trp-P-1에 대해서도 각각 67%와 63%의 높은 억제활성을 나타내었다. 그리고 광천수의 항암활성을 규명하기 위한 암세포 성장억제 효과에서는 시료농도 $50{\mu}g/well$ 첨가 시 A549, Hela, AGS 및 MCF-7에 대해서 각각 $66\%,\;45.6\%,\;37.7\%$ 및 $47.6\%$의 억제효과를 나타내었다. 또한 인간 정상 신세포 293에 대한 온천수 농도에 따른 세포독성 효과는 $20\%$ 이하의 낮은 생육 억제율을 보였으며 이것은 광천수가 정상세포에 대해서는 비교적 낮은 독성효과를 나타냄을 알 수 있었다.

• 한국임상보건과학회지
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• 제6권1호
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• pp.1065-1073
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• 2018

Purpose. In this study, we aim to clarify the correlation between happiness, appearance, and happiness index among many happiness factors based on the influence of quality of life on the quality of life and the affect of appearance on the happiness index. Methods. We conducted a self - filling questionnaire survey for college students in Busan from March 30 to May 10, 2017, and analyzed 392 copies of the 412 questionnaires, excluding 20 inappropriate copies. In the questionnaire, categorical data were analyzed by frequency and percentage (%) using the SPSS program (ver. 23.0, Chicago, Illinois, USA) by examining 11 items of general characteristics, successive data are presented as mean standard deviation. Results. The higher the grades, the better the dating. Women(3.32) are more likely than men(2.74) at the appearance interest(p>0.001) and the higher the grades, the better. If it's dating someone else, higher than not to do at the appearance interest and all of the questions showed higher interest in appearance. Also there was a high percentage of thought'My life is ideal in all aspects'If it's dating someone else, higher than not to do (p=0.007) Conclusion. At present, There is a high interest in the appearance of dating. In addition, the happiness index according to the current resentment status was higher in both the single item happiness index and the 5 item happiness index, and was significant in the item "My life is ideal in all aspects". Therefore, it is related to the happiness index as well as the appearance interest. Finally, whether or not dating and appearance interest play a role in raising the happiness of the individual.