• Proceedings of the Computational Structural Engineering Institute Conference
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• 2001.10a
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• pp.159-166
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• 2001

Structural optimization often requires the evaluation of design sensitivities. The Semi Aanalytic method(SAM) for computing sensitivity is popular in shape optimization because this method has several advantages. But when relatively large rigid body motions are identified for individual elements, the SA method shows severe inaccuracy. In this paper, the improvement of design sensitivities corresponding to the rigid body mode is evaluated by exact differentiation of the rigid body modes. Moreover, the error of the SA method caused by numerical difference scheme is alleviated by using a series approximation for the sensitivity derivatives and considering the higher order terms. Finally, this paper shows that the refined SA method including the iterative method improves the results of sensitivity analysis in dynamic problems.

• Journal of Welding and Joining
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• v.16 no.3
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• pp.141-147
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• 1998

Design sensitivity analysis of a vehicle system is an essential tool for design optimization and trade-off studies. Most optimization algorithms require the derivatives of cost and constraint function with respect to design in order to calculate the next improved design. This paper presents an efficient algorithm application for the design sensitivity analysis, using the direct differentiation method. A mounting area of suspension that welded on chassis frame is analyzed to show the validity and the efficiency of the proposed method. A mounting area of suspension that welded on chassis frame is analyzed to show the validity and the efficiency of the proposed method.

• Journal of the Society of Naval Architects of Korea
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• v.35 no.3
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• pp.54-61
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• 1998

This paper presents a prediction method of natural frequencies of vertical hull girder vibration based on design sensitivity analysis in case of design modification and the variation of loading condition. The resented method premises the vibration analysis by the transfer matrix method. Governing sensitivity equation is derived from the direct differentiation of state vector and transfer matrix to parameters and its transfer over all the hull girder elements. Derivatives of natural frequencies and mode shapes are determined by two trial calculation of the governing equation. Using the derivatives, the changes of natural frequencies and mode shapes can be predicted when mass and stiffness parameter's are changed. As results, it is possible to optimize ship structure as well as to avoid troublesome calculation in hull girder vibration analysis rationally and efficiently. To verify the accuracy and efficiency of the resented method numerical results obtained by both the sensitivity analysis and the ordinary reanalysis far a real ore/bulk carrier in case of the change of mass and stiffness parameters are compared.

• Transactions of the Korean Society of Mechanical Engineers
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• v.15 no.6
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• pp.1852-1860
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• 1991

A shape design sensitivity of the elastic deformation due to a change of traction boundary condition is presented. The solution of governing equations for a linear elasticity problem is obtained by finite element method and the traction boundary is defined by design variables. The performance functional to be considered involves both the domain and boundary integral. Variations of geometry can be defined as design velocity. Using material derivative concept and adjoint equations, the design sensitivity is derived by Lagrange multiplier method. For a given geometry of a structure, the change of traction boundary is described by the tangential component of the design velocity only. The final result for the shape design sensitivity is formulated as the boundary integral form, the integrand is defined by tangential component of design velocity and first order derivatives of parameters. Numerical implementation of design sensitivity is discussed and is compared with the difference of the actual values.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.25 no.1
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• pp.153-160
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• 2001

A general procedure for the design sensitivity analysis of structural dynamic problems has been presented in frame of the FRF-based substructuring formulation. For a system response function, the proposed method gives a parametric design sensitivity formula in terms of the partial derivatives of the connection element properties and the transfer matrix of the subsystems. The derived design sensitivity formula is applied to an engine mount system. An interior noise problem in the passenger car is analyzed using the FRF-based substructuring method and the proposed formulation is adopted to study the response variations with respect to the dynamic characteristics of the engine mounts and the bushes. To obtain the FRFs, a finite element model is built for the engine mount structures, and test data is used for the trimmed body including cabin cavity. The comparison of sensitivities derived by the proposed method and the finite difference method shows that the proposed method is efficient and accurate. The proposed sensitivity analysis method indicates effectively the most sensitive location to the interior noise among the engine mounts and the bushes.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.05a
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• pp.796-801
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• 2002

The goal of this research is the shape design of the valve using a computer simulation. For an analysis a basic mathematical model describing compression cycle is considered as consisting of five sets of coupled equations. These are the volume equation (kinematics), valve dynamic equation (dynamics), ideal gas equation (thermodynamics), Bernoulli equation (fluid dynamics), and dynamic equation of fluid particle based on Helmholtz equation (acoustics). Valve motion is made by the superposition of free vibration modes obtained by the finite element method. That is, the eigenvalues and eigenvectors are the sufficient modeling factors fur the valve in the simulation program. Thus, to design a shape of the valve, shape design sensitivity through chain-ruled derivatives is considered from two sensitivity coefficients, one is the design sensitivity of the capability of compressor with respect to the eigenvalues of the valve, and the other is the design sensitivity of the eigenvalue with respect to the shape change of the valve. In this research, the continuum design sensitivity analysis concepts are used for the latter.

• Applied Chemistry for Engineering
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• v.10 no.8
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• pp.1169-1174
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• 1999

2-Diazo-1-naphthoquinone-5-sulfonyl chloride(NQD-Cl) was synthesized from sodium 2-diazo-naphthoquinone-5-sulfonate by chlorination. NQD-Cl was esterified with hydroxybenzophenones to give several 1,2-naphthoquinone-(2)-diazide-5-sulfonic acid ester derivatives(NQD-esters). We have compared benzophenone derivatives with methoxy group to benzophenone derivatives with hydroxy group. Solubility of each NQD-ester was studied. Each of NQD-esters was formulated with novolac base resin and PS plates were manufactured. Photosensitivity, bleachability, compatible exposed time and relative sensitivity were determined by UV spectrophotometry, imaged by UV lithographic techniques, and the gray scale method. According to the number of substituted NQD group, it showed that relative sensitivity was different from gray scale method. NQD-esters with methoxy group showed a good solubility and higher sensitivity than commercial PS ones.

• International Journal of Aeronautical and Space Sciences
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• v.17 no.2
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• pp.268-283
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• 2016

Aircraft manufacturing companies have to consider multiple derivatives to satisfy various market requirements. They modify or extend an existing aircraft to meet new market demands while keeping the development time and cost to a minimum. Many researchers have studied the derivative design process, but these research efforts consider baseline and derivative designs together, while using the whole set of design variables. Therefore, an efficient process that can reduce cost and time for aircraft derivative design is needed. In this research, a more efficient design process is proposed which obtains global changes from local changes in aircraft design in order to develop aircraft derivatives efficiently. Sensitivity analysis was introduced to remove unnecessary design variables that have a low impact on the objective function. This prevented wasting computational effort and time on low priority variables for design requirements and objectives. Additionally, uncertainty from the fidelity of analysis tools was considered in design optimization to increase the probability of optimization results. The Reliability Based Design Optimization (RBDO) and Possibility Based Design Optimization (PBDO) methods were proposed to handle the uncertainty in aircraft conceptual design optimization. In this paper, Collaborative Optimization (CO) based framework with RBDO and PBDO was implemented to consider uncertainty. The proposed method was applied for civil jet aircraft derivative design that increases cruise range and the number of passengers. The proposed process provided deterministic design optimization, RBDO, and PBDO results for given requirements.

• BMB Reports
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• v.28 no.6
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• pp.471-476
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• 1995

Acetolactate synthase (ALS) catalyzes the first common step in the biosynthesis of valine, leucine, and isoleucine. ALS is the target enzyme for several classes of structually diverse herbicides. We have synthesized 4,6-dimethoxypyrimidine derivatives as ALS inhibitors, and their inhibitory activities on barley ALS were determined. $IC_{50}$ values for the derivatives are 0.2~200 ${\mu}m$. K11570, the most potent ALS inhibitor with $IC_{50}$ of 0.2 ${\mu}m$, showed mixed-type inhibition with respect to substrate pyruvate, and the progress curves for ALS inhibition by K11570 indicated that the amount of inhibition increased with time. Inhibition-competition experiments were carried out and indicated that three different classes of inhibitors, K11570, a sulfonylurea Ally, and leucine, bind to ALS in a mutually exclusive manner. Chemical modification of tryptophanyl and tyrosyl residues of ALS decreased the sensitivity of ALS to K11570, while cysteine modification did not affect the sensitivity. These results suggest that tryptophanyl and tyrosynyl residues are probably located at or near the inhibitor binding site.

• Proceedings of the KIEE Conference
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• 1996.07a
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• pp.154-156
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• 1996

A new method for electric resistivity tomography(ERT) is developed for geophysical inverse problems by adapting the sensitivity analysis. The outputs of the potential electrodes are computed using two dimensional finite element method in the wave number space by Fourier transforming the governing equations. The resistance distribution in the region of interests, which makes the computed potential distribution coincide with the measured potential, is found by minimizing the objective function using an optimization method. In this process the sensitivity analysis is introduced in order to compute the derivatives of the objective function. And an adjoint variable method is used to save the computational efforts for sensitivity coefficients.