• Preventive Nutrition and Food Science
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• 제1권2호
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• pp.269-277
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• 1996

Bacteriocins are proteins produced by a heterogeneous group of bacteria that have a bactericidal effect on closely related organisms. Recently, bacteriocins from lactic acid bacteria and other food-related organisms have been the subject of much research because of their potential as food biopreservatives. Various modifications of agar plate diffusion assays are the most widely used methods even though the limitations of such assays are generally recognized. The ability to obtain a concentrated crude preparation on bacteriocin by optimizing production parameters greatly simplifies recovery of bacteriocin on subsequent purification steps. Some studies performed to optimize bacteriocins have been purified to homogeneity, and the amino acid sequences of many of these purified bacteriocins have been determined. Obtaining characterization data on purified bacteriocin will minimize the risk of overlapping of research and confusion on identification of these compounds. Several me-chanisms leading to cell death have been hypothesized. These include depletion of the proton motive force(PMF) across the cell membrane: RNase and/or DNase activity within the sensitive cell; and pore formation and lysis of sensitive cells at the cell membrane.

• Archives of Pharmacal Research
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• 제9권3호
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• pp.131-138
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• 1986

A specific and sensitive gas chromatographic (GC) procedure with the flame photometric detector (FPD) was developed for determination of barbiturates such as barbital, allobarbital, secobarbital, phenobarbital and thiopental in plasma. In order to evaluate the performance of the FPD, the results were campared with those of the flame ionization detector (FID). After extraction of barbiturates from plasma, the barbiturates were quantitatively N, N-dimethylthiometyl (MTM)-derivatized with methylthiomethyl chloride in 1, 8-diazabicyclo [5, 4, 0] undec-7-ene catalyst. The data indicate that the FPD is about 4 times more sensitive than the FID for barbiturates, although it is less reproducible. The FPD also produced chromatogram with less back ground for extracted plasma sample. The FPD also produced chromatogram with less background for extracted plasma sample. The minimum detectable amount of MTM-thiopental on 3% OV-225 column was 4, 4fmol and that of other MTM-barbiturate was about 10.0fmol.

• 설비공학논문집
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• 제18권1호
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• pp.31-37
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• 2006

The present study has been experimentally investigated the effect of geometric and operating parameters on the two-phase flow distribution of refrigerants in a horizontal T-junction. The operating parameters were the kind of refrigerants (R-22, R- l34a, and R-410A), saturated temperature, and the inlet mass flux and quality. The geometric parameters were the tube diameter and the tube diameter ratio. The measured data of refrigerants were compared with the values predicted using the models developed by several researchers for air/water or steani/water two-phase flow. Among the operating parameters, the inlet Quality was the most sensitive to the mass flow rate ratio. Between the geometric parameters, the tube diameter ratio was more sensitive than tube diameter.

• 제어로봇시스템학회논문지
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• 제2권4호
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• pp.330-336
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• 1996

An real-time active beacon localization system for mobile robots is developed and implemented. This system permits the estimation of robot positions when detecting light sources by PSD(Position Sensitive Detector) sensor which are placed sparsely over the robots work space as beacons(or landmarks). An LSE(Least Square Estimation) method is introduced to calibrate the internal parameters of a model for the beacon and robot position. The proposed system has two operational modes of position estimation. One is the initial position calculation by the detection of two or more light sources positions of which are known. The other is the continuous position compensation that calculates the position and heading of the robot using the IEKF(Iterated Extended Kalman Filter) applied to the beacon and dead-reckoning data. Practical experiments show that the estimated position obtained by this system is precise enough to be useful for the navigation of robots.

• 한국안전학회지
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• 제14권3호
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• pp.69-77
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• 1999

As the use of automatic handling equipment for sensitive semiconductor devices is rapidly increased, manufacturers of electronic components and equipment need to be more alert to the problem of electrostatic discharges(ESD). Semiconductor devices such as IC, LSI, VLSI become a high density pattern of being more fragile by ESD phenomena. One of the most common causes of electrostatic damage is the direct transfer of electrostatic charge from the human body or a charged material to the electrostatic discharge sensitive devices. Accordingly, characteristics of electrostatic attenuation in domestic semiconductor devices is investigated to evaluate the ESD phenomina in the semiconductors in this paper. The required data are obtained by Static Honestmeter. Also The results in this paper can be used for the prevention of semiconductor failure by ESD.

• The Korean Journal of Physiology and Pharmacology
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• 제6권3호
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• pp.139-142
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• 2002

To examine intracellular signaling of human $S1P_3\;(hS1P_3),$ a sphingosine 1-phosphate (S1P) receptor in plasma membrane, $hS1P_3$ DNA was transfected into RH7777 rat hepatoma cell line, and the inhibition of forskolin-induced cAMP accumulation and activation of MAP kinases by S1P were tested. In $hS1P_3$ transformants, S1P inhibited forskolin-induced activation of adenylyl cyclase activity by about 80% and activated MAP kinases in dose-dependent and pertussis-toxin (PTX) sensitive manners. In oocytes expressing $hS1P_3$ receptor, S1P evoked $Cl^-$ conductance. These data suggested that PTX-sensitive G proteins are involved in $hS1P_3-mediated$ signaling, especially the positive action of S1P in cell proliferation. The potential advantages of rat hepatoma cells for the research of sphingosine 1-phosphate receptor are discussed.

• Journal of Electrical Engineering and Technology
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• 제12권4호
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• pp.1376-1385
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• 2017

This paper proposes a method for estimating the expected frequency of voltage swells caused by asymmetrical faults in a power system. Although voltage swell is less common than voltage sag, repeated swells can have severe destructive impact on sensitive equipment. It is essential to understand system performance related to voltage swells for finding optimal countermeasures. An expected swell frequency at a sensitive load terminal can be estimated based on the concept of an area of vulnerability (AOV) and long-term system fault data. This paper describes an effective method for calculating an AOV to voltage swells. Interval estimation for an expected swell frequency is also presented for effective understanding of system performance. The proposed method provides long-term performance evaluation of the frequency and degree of voltage swell occurrences.

• 대한전기학회논문지
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• 제35권5호
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• pp.193-198
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• 1986

In this paper, 1-168 hours ahead load prediction algorithm is developed for power system economic weekly operation. Total load is composed of three components, which are base load, week load and weather-sensitive load. Base load and week load are predicted by moving average and exponential smoothing method, respectively. The days of moving average and smoothing constant are optimally determined. Weather-sensitive load is modeled by linear form. The paramiters of weather load model are estimated by exponentially weighted recursive least square method. The load prediction of special day is very tedious, difficult and remains many problems which should be improved. Test results are given for the day of different types using the actual load data of KEPCO.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 제37회 하계학술대회 논문집 D
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• pp.1840-1841
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• 2006

Plants with long time-delays can not be often controlled effectively using a simple PID controller. The main reason for this is that the additional phase lag contributed by the time-delay tends to destabilize the closed-loop system. The stability problem can be solved by smith predictor. However, in this case responses are very sensitive to the estimated model errors. To reduce sensitive problem, this paper is presented based on virtual reference feedback tuning of the time delay plant using the closed-loop test to find parameters for a PID controller using the closed-loop test data.

• Water Engineering Research
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• 제5권3호
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• pp.133-146
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• 2004

Soil and water assessment tool (SWAT) was simulated based on the default parameters and a priori soil parameter estimation method in Bocheong watershed of Korea. The performance of the model was tested against the measured daily runoff data for 5 years between 1993 and 1997. The sensitivity analysis of SWAT model parameters was conducted to identify the most sensitive model parameters affecting the model output. The results of SWAT simulation indicate that the overall performance of SWAT in calculating daily runoff is reasonably acceptable. However, there is a problem in estimating the low flow components of streamflow since the low flow components simulated by SWAT are significantly different from the measured low flow. The sensitivity analysis with SWAT points out that soil related parameters are the most sensitive parameters affecting surface and ground water balance components and groundwater flow related parameters exhibit negligible sensitivity.