• 제목/요약/키워드: Sensitive

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Cephalosporin C 내성과 7-Aminocephalosporanic Acid 감수성을 지닌 균주의 선발 및 특성 (Isolation and Characterization of a Cephalosporin C Resistant and 7-Aminocephalosporanic Acid Sensitive Strain)

  • 김욱현;박용춘;임재윤;김영창
    • 한국미생물·생명공학회지
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    • 제23권5호
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    • pp.556-558
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    • 1995
  • A strain which showed cephalosporin C resistance and 7-aminocephalosporanic acid sensitivity was isolated from nature. Among the isolates, SS5 was sensitive to cephalosporin C, penicillin G, ampicillin, 7-aminocephalosporanic acid, 6-aminopenicillanic acid, and 7-aminodeacetoxy cephatosporanic acid at concentrations of 1,000 $\mu $g/ml, 2,000 $\mu $g/ml, 3,000 $\mu $g/ml, 30 $\mu $g/ml 100 $\mu $g/ml and 100 $\mu $g/ml, respectively. But SS5 was sensitive at very low concentration of chloramphenicol, kanamycin, neomycin, streptomycin and tetracycline. Since SS5 was sensitive to 7-ACA (30 $\mu $g/ml) and didn't have $\beta $-lactamase activity on the cephalosporin C, SS5 could be useful as an indicator strain for the production of 7-ACA, which is an important precursor for the synthesis of many semisynthetic cephalosporins.

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변위 감응형 충격흡수기에 관한 연구 (A Study on the Stroke Sensitive Shock Absorber)

  • 박재우;주동우;김영호
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 1997년도 춘계학술대회 논문집
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    • pp.85-90
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    • 1997
  • In the stroke sensitive shock absorber, the oil path is formed along the internal cylinder surface to make the eli flow during piston's upper-lower reciprocation movement. With constraint to the conventional shock absorbers which show one dynamic characteristic curve, stroke sensitive shock absorber shows two kins of dynamic characteristic according to the stroke, In the study, analysis on the damping force generation process and dynamic behaviour characteristics of stroke sensitive shock absorber is performed, the valve characteristics being considered more precise information about design and damping performance analysis.

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Mycobacterium smegmatis를 이용한 Viomycin의 내성 및 작용 기전에 관한 연구 (Studies on the Mechanism of Resistance to and Mode of Action of Viomycin in Mycobacterium smegmatis)

  • 최응칠
    • 약학회지
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    • 제24권1호
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    • pp.1-10
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    • 1980
  • Viomycin inhibited polypeptide biosynthesis, initiation complex formation and translocation of peptidyl-tRNA on ribosomes derived from a sensitive strain of Mycobacterium smegmatis (R-15), but not significantly on ribosomes from viomycin-resistant mutants(R-31 and R-43). The inhibition of translocation was stronger than that of initiation complex formation in the sensitive strain. The binding of [$^{14}C$] tuberactinomycin O, a viomycin analog, to ribosomal particles was studied by Millipore filter method. The sensitive ribosome exhibited higher affinity for the antibiotic than the resistant ribosomes. The resistance was localized on the large ribosomal subunit in a mutant(R-31), and on the small subunit in another mutant(R-43). The binding of the drug to the sensitive ribosomal subunit was markedly reduced by combination with the resistant pair subunit, and the entire ribosome became resistant to the antibiotic.

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The Examination of Subgroup-Sensitive Risks and Needs among Delinquent Adolescents in the US

  • Lim, Ji-Young
    • International Journal of Human Ecology
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    • 제8권2호
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    • pp.47-60
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    • 2007
  • While there is growing evidence regarding the subgroup-sensitive nature of risk factors among delinquent adolescents, researchers have paid little attention to the tracking of risks and needs by subgroups (e.g., gender, ethnicity, and the timing of onset for delinquency) among youth who are currently involved in the juvenile court system. Therefore, greater empirical attention directed toward subgroup-sensitive risk factors experienced by delinquent adolescents is thought to be both timely and necessary. A final convenience sample of 2167 court-involved adolescents in the US was used to specify subgroup-sensitive risks and needs. The results demonstrated that there were various levels of risks according to subgroups associated with gender, ethnicity, and onset for delinquency group. The findings of this study add to the extant literature on delinquency by demonstrating the importance of considering subgroups associated with gender, ethnicity, and the timing of onset for delinquency when practicing treatment or intervention programs with delinquent adolescents.

휠 로더용 폐회로형 부하 감응 유압 제어 시스템의 특성 해석 (The Characteristic Analysis of the Load-sensitive Hydraulic Control System for Closed Center Type of a Wheel Loader)

  • 이승현;송창섭;정춘국
    • 대한기계학회논문집A
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    • 제31권9호
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    • pp.934-942
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    • 2007
  • In this study, the characteristics of the load-sensitive hydraulic control system for closed center type of a wheel loader were analyzed using developed analysis program based on Amesim tool. From the parametric analysis, the effects of each factor were revealed. Through the simulation with varying parameters, the system parameter effects on the controllable region and the pump pressure and load pressure variations were studied. The results were compared with the experimental ones. The results and discussions of the present paper could aid in the design of a load-sensitive hydraulic control system for closed center type.

표면압력 분포 가시화를 위한 압력감응 페인트의 제작 (Fabrication of Pressure Sensitive Paint for Visualizing Surface Pressure Distribution)

  • 안최란;기효진;진병규;김정균;김석범;조용화;노영철;최용덕;곽재수;최용규
    • 항공우주시스템공학회지
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    • 제2권3호
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    • pp.19-23
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    • 2008
  • We have fabricated pressure sensitive paint films consisting of PtTFPP activators dispersed in fluorinated polymer matrix. This matrix material is unique in its composition and structure. We evaluated the oxygen quenching effects, and thus the pressure sensitivity, of the fabricated films in terms of various processing parameters. Based on the experimental results, we anticipate that a good but new pressure sensitive paint would be presented through further elaboration of the polymer compositions and optimization of the processing conditions.

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Enhanced Locality Sensitive Clustering in High Dimensional Space

  • Chen, Gang;Gao, Hao-Lin;Li, Bi-Cheng;Hu, Guo-En
    • Transactions on Electrical and Electronic Materials
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    • 제15권3호
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    • pp.125-129
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    • 2014
  • A dataset can be clustered by merging the bucket indices that come from the random projection of locality sensitive hashing functions. It should be noted that for this to work the merging interval must be calculated first. To improve the feasibility of large scale data clustering in high dimensional space we propose an enhanced Locality Sensitive Hashing Clustering Method. Firstly, multiple hashing functions are generated. Secondly, data points are projected to bucket indices. Thirdly, bucket indices are clustered to get class labels. Experimental results showed that on synthetic datasets this method achieves high accuracy at much improved cluster speeds. These attributes make it well suited to clustering data in high dimensional space.

감도해석기법을 이용한 구조물의 진동특성 최적화 수법의 실제 기계에의 응용 (The Application of Structural Dynamic Optimization for the Actual Machine U sing Sensitive Analysis Techniques)

  • 박석주
    • Journal of Advanced Marine Engineering and Technology
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    • 제16권3호
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    • pp.51-57
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    • 1992
  • Authors had analyzed the Press machine's vibrational characteristics by Substructure Synthesis Method. This paper discribes the structural Dynamic Optimization for the machine using Sensitive Analysis Method. The substructure synthesis method and sensitive analysis methods are used for the vibration analysis and structural modification. The results obtained are as follows ; 1. The tooling precision of the press machine is ruled by the bending vibration of the slide. 2. The structural Modification Method for minimizing impact responses is proposed, and modal analysis and sensitive analysis method are introduced to solve it. 3. The impact responses of running machine were reduced to 40% of the unmodified machine by using the proposed method.

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Bacterial Hormone-Sensitive Lipases (bHSLs): Emerging Enzymes for Biotechnological Applications

  • Kim, T. Doohun
    • Journal of Microbiology and Biotechnology
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    • 제27권11호
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    • pp.1907-1915
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    • 2017
  • Lipases are important enzymes with biotechnological applications in dairy, detergent, food, fine chemicals, and pharmaceutical industries. Specifically, hormone-sensitive lipase (HSL) is an intracellular lipase that can be stimulated by several hormones, such as catecholamine, glucagon, and adrenocorticotropic hormone. Bacterial hormone-sensitive lipases (bHSLs), which are homologous to the C-terminal domain of HSL, have ${\alpha}/{\beta}-hydrolase$ fold with a catalytic triad composed of His, Asp, and Ser. These bHSLs could be used for a wide variety of industrial applications because of their high activity, broad substrate specificity, and remarkable stability. In this review, the relationships among HSLs, the microbiological origins, the crystal structures, and the biotechnological properties of bHSLs are summarized.

도공액의 보수성에 관한 연구(제5보)-알칼리 반응형 보수.유동성 개량제의 적용- (A study on the Water Retention of Coating Colors(V)-Application of Alkali Sensitive Water Retention and Rheology Modifiers-)

  • 이용규;엄기용
    • 펄프종이기술
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    • 제29권4호
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    • pp.28-35
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    • 1997
  • Sole-binder formulation has been recently introduced to solve the problems of coating process and printability caused by use of natural polymer However, the decrease of natural polymer application causes another problem in paper coating. Therefore, synthetic thickener is used to get similar effect to natural polymer usage. In this study. low shear viscosity, dewatering of coating colors were measured to evaluate the performance of the alkali sensitive water retention and rheology modifiers. The effects of alkali sensitive thickener on the physical properties of coated paper and printability were also investigated. The gloss and printability of coated paper containing the synthetic flow modifier were similar or superior to those of CMC containing coated paper. This modifier was also effective to improve the problems caused by the use of starch. The results indicated that the flow modifier synthesized with alkali sensitive thickener can reduce the problems of natural polymer and could be a good substitute f3r a natural polymer.

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