• Title/Summary/Keyword: Sen's method

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Spherical Robot for Planetary Explorations: An Approach to Educating Concepts of Mechatronics and Robotics to High School Students

  • Kim, Sooyoung;Kim, Seonje;Kim, Byungkyu;Sen, Soumen
    • Journal of Aerospace System Engineering
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    • v.14 no.2
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    • pp.36-43
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    • 2020
  • Many countries and international organizations have carried out rover missions to explore planetary surfaces. Accordingly, the demand for mechatronics education, which is closely related to building exploratory robots, is also steadily increasing. However, due to the complexity in understanding the background information needed for mechatronics, it is hard for pre-college students to study such process. In this study, we suggest an educational platform for mechatronics using a combined robot kit with a spherical robot and a smartphone application. To provide a visual understanding, the dynamic model of the robot is constructed while analyzing the error between actual driving and a simulation, and the educational algorithm of the game and a feedback method are proposed to improve the learning efficacy by considering the user's level of knowledge of mechatronics. We use this educational spherical robot to develop a curling game platform that can impart engineering education even when students lack significant knowledge.

A Study on Clothing Life Style and Clothing Selection Behavior of the New Generation Consumer (신세대의 의생활양식과 의복선택행동에 관한 연구)

  • 김미경;이선재
    • Journal of the Korean Society of Costume
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    • v.24
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    • pp.217-233
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    • 1995
  • The ultimate purpose of this study is to suggest the most effective marketing strategy for the clothing consumer market based on the new generation consumer's clothing selection behavior analysis. In this thesis, it is appempted to make a progress in the new gen-eration consumer's clothing life style types, in clothing purchase behavior analysis among the clothing life style, and also in the marketing strategy for marketers. The subjects selected for the final analysis are 412 the new gerneration women of age 20 thru 34 in seoul and satellite town area. Data were processed the spss package program. As for the analytic method, factor analysis, clustering analysis, XCross-tubulation, F-test with ANOVA, frequency and percentage were applied in the survey. The major findings are as following : life style is classified into four types : The characteristic fashion-directory type(25.7%) ; The reason traditional type(9.0%) ; The sen-sitivity fashion-following type(11.0%) ; The community brand-conscious type(54.3%). 2 Clothing life style types characteristic of the new generation consumer proved that clothing life style types are a significant difference according to the life style, the fashion consciousness and the average monthly spend-ing on clothing. 3. There is an important discrimination according to the clothing life style types in their clothing purchase behavior such as infor-mation usage, clothing choice criterion and brand loyalty. 4. Based on the result of our analysis and the review of literature, the marketing strategy is suggested that characteristic and new design development is efficient way to consumer's purchase need. Therefore apparel industary which pursue an added value must frame marketing strategy on the basis of the target consumer's sensitivity characteristic according to the life style and fashion consciousness.

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Genome-wide Analysis of Aberrant DNA Methylation for Identification of Potential Biomarkers in Colorectal Cancer Patients

  • Fang, Wei-Jia;Zheng, Yi;Wu, Li-Ming;Ke, Qing-Hong;Shen, Hong;Yuan, Ying;Zheng, Shu-Sen
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.1917-1921
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    • 2012
  • Background: Colorectal cancer is one of the leading causes of mortality worldwide. Genome wide analysis studies have identified sequence mutations causing loss-of-function that are associated with disease occurrence and severity. Epigenetic modifications, such DNA methylation, have also been implicated in many cancers but have yet to be examined in the East Asian population of colorectal cancer patients. Methods: Biopsies of tumors and matched non-cancerous tissue types were obtained and genomic DNA was isolated and subjected to the bisulphite conversion method for comparative DNA methylation analysis on the Illumina Infinium HumanMethylation27 BeadChip. Results: Totals of 258 and 74 genes were found to be hyper- and hypo-methylated as compared to the individual's matched control tissue. Interestingly, three genes that exhibited hypermethylation in their promoter regions, CMTM2, ECRG4, and SH3GL3, were shown to be significantly associated with colorectal cancer in previous studies. Using heatmap cluster analysis, eight hypermethylated and 10 hypomethylated genes were identified as significantly differentially methylated genes in the tumour tissues. Conclusions: Genome-wide methylation profiling facilitates rapid and simultaneous analysis of cancerous cells which may help to identify methylation markers with high sensitivity and specificity for diagnosis and prognosis. Our results show the promise of the microarray technology in identification of potential methylation biomarkers for colorectal cancers.

A New Strategy to Improve the Efficiency and Sustainability of Candida parapsilosis Catalyzing Deracemization of (R,S)-1-Phenyl-1,2-Ethanediol Under Non-Growing Conditions: Increase of NADPH Availability

  • Nie, Yao;Xu, Yan;Hu, Qing Sen;Xiao, Rong
    • Journal of Microbiology and Biotechnology
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    • v.19 no.1
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    • pp.65-71
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    • 2009
  • Microbial oxidoreductive systems have been widely used in asymmetric syntheses of optically active alcohols. However, when reused in multi-batch reaction, the catalytic efficiency and sustainability of non-growing cells usually decreased because of continuous consumption of required cofactors during the reaction process. A novel method for NADPH regeneration in cells was proposed by using pentose metabolism in microorganisms. Addition of D-xylose, L-arabinose, or D-ribose to the reaction significantly improved the conversion efficiency of deracemization of racemic 1-phenyl-1,2-ethanediol to (S)-isomer by Candida parapsilosis cells already used once, which afforded the product with high optical purity over 97%e.e. in high yield over 85% under an increased substrate concentration of 15 g/l. Compared with reactions without xylose, xylose added to multi-batch reactions had no influence on the activity of the enzyme catalyzing the key step in deracemization, but performed a promoting effect on the recovery of the metabolic activity of the non-growing cells with its consumption in each batch. The detection of activities of xylose reductase and xylitol dehydrogenase from cell-free extract of C. parapsilosis made xylose metabolism feasible in cells, and the depression of the pentose phosphate pathway inhibitor to this reaction further indicated that xylose facilitated the NADPH-required deracemization through the pentose phosphate pathway in C. parapsilosis. moreover, by investigating the cofactor pool, the xylose addition in reaction batches giving more NADPH, compared with those without xylose, suggested that the higher catalytic efficiency and sustainability of C. parapsilosis non-growing cells had resulted from xylose metabolism recycling NADPH for the deracemization.

A Study on Hybrid Characteristics in the Work of Chinese Rising Fashion Designers (중국 신진 패션 디자이너의 작품에 나타난하이브리드 특성 연구)

  • Bin, Sen;Yum, Haejung
    • Journal of Fashion Business
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    • v.24 no.1
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    • pp.1-14
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    • 2020
  • Based on the trend of pluralization and globalization the collapse of national borders now is a manifestation of mixed and compromised cultures and societies. It is also emerging as a hybrid fashion in fashion. Hybrid fashion means creating a new image by mixing various cultures beyond the time and space. This study aims to analyze the current state of Chinese fashion design and present its direction by grasping the characteristics of hybrids in the works of rising Chinese fashion designers in the era of pluralization. The research method was literature review and empirical research. According to the selection criteria of new fashion designers, 6 new fashion designers of 5 fashion brands were selected and their total 458 points works were analyzed. The analysis results are as follows. First, most of the time trade-offs were 'past and present' trade-offs that express Chinese traditional culture and the image of the past with modern design. The trade-offs between 'present and future' is expressed by mixing print patterns, colors and light with fractal art. Second, spatial trade-offs was expressed in the way of expressing Chinese themes in the composition of western clothing, expressing the Western themes in oriental colors, and inspired by Japanese culture expressed by deconstructionism, Third, the gender mix mainly used dark embroidery on women's clothing, while the men's wear showed a delicate feminine charm with a surreal pattern on thin and transparent gauze fabric.

A Study on the Application of an IPA Method for the Analysis of Visitor Satisfaction - Focusing on Chinese Visitors in Gyeongju Yangdong Village - (관광객 만족도 분석을 위한 IPA 기법 적용 연구 -경주 양동마을 방문 중국인을 대상으로-)

  • Cao, Lin-Sen;Xia, Tian-Tian;Kang, Tai-Ho
    • Journal of the Korean Institute of Landscape Architecture
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    • v.45 no.3
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    • pp.107-115
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    • 2017
  • As a simple and practicable method, an Importance-Performance Analysis(IPA) is often used as a tool to study the satisfaction of tourists in Tourism. The IPA has two dimensions to attribute importance and performance(or satisfaction as in satisfaction research), and generally uses an interviewee self-reported approach to acquire performance and importance data. Many scholars have pointed out that the traditional IPA cannot meet the premise of its establishment. Therefore, several revised IPA have been proposed. Among them, Deng's IPA is the most representative. There are not many contrastive analyses between the traditional IPA and revised IPA in academia. The lack of comparative study will make it difficult to judge the difference and effectiveness of different IPA techniques. Taking Gyeongju Yangdong Village as an example, this study investigated and researched the degree of satisfaction of Chinese tourists using the traditional IPA method and Deng's modified IPA method respectively, and then analysed the differences between the two methods and their causes. Based on the analysis results, the study put forward suggestions for the improvement of tourism management in Gyeongju Yangdong Village.

Suggestion of a Groundwater Quality Management Framework Using Threshold Values and Trend Analysis (문턱값과 추세분석을 이용한 지하수 수질관리체계 구축을 위한 연구)

  • An, Hyeonsil;Jee, Sung-Wook;Lee, Soo Jae;Hyun, Yunjung;Yoon, Heesung;Kim, Rak-Hyeon
    • Journal of Soil and Groundwater Environment
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    • v.20 no.7
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    • pp.112-120
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    • 2015
  • Statistical trend analysis using the data from the National Groundwater Quality Monitoring Network (NGQMN) of Korea was conducted to establish a new groundwater quality management framework. Sen’s test, a non-parametric statistical method for trend analysis, was used to determine the linear trend of the groundwater quality data. The analysis was conducted at different confidence levels (i.e., at 70, 80, 90, 95, and 99% confidence levels) for three of groundwater quality parameters, i.e., nitrate-nitrogen, chloride, and pH, which have sufficient time series of the NGQMN data between 2007 and 2013. The results showed that different trends can be determined for different depths even for the same monitoring site and the numbers of wells having significant trends vary with different confidence levels. The wells with increasing or decreasing trends were far less than the wells with no trend. Chloride had more wells with increasing trend than other parameters. On the other hand, nitrate-nitrogen had the most wells with increasing trend and concentration exceeding 75% of the threshold values (TVs). Based on the methodology used for this study, we suggest including groundwater TVs and trend analysis to evaluate groundwater quality and to establish an advanced groundwater quality management framework.

Development of an Open Sandwich Fluoroimmunoassay Based on FRET (FRET에 기반한 Open Sandwich Fluoroimmunoassay)

  • Wei, Quande;Lee, Moon-Kwon;Seong, Gi-Hun;Choo, Jae-Bum;Lee, Eun-Kyu
    • KSBB Journal
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    • v.22 no.6
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    • pp.426-432
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    • 2007
  • We have developed a sensitive, one-step, homogeneous open sandwich fluoroimmunoassay (OsFIA) based on fluorescence resonance energy transfer (FRET) and luminescent semiconductor quantum dots (QDs). In this FRET assay, estrogen receptor-$\beta$ (ER-$\beta$) antigen was incubated with QD-labeled anti-ER-$\beta$ monoclonal antibody and AF (Alexa Fluoro)-labeled anti-ER polyclonal antibody for 30 minutes, followed by FRET measurement. The dye separation distance was estimated to be between $80\sim90\;{\AA}$. The present method is rapid, simple and highly sensitive, and did not require the bound/free reagent separation steps and solid-phase carriers. A concentration as low as 0.05 nM (2.65 ng/ml) receptor was detected with linearity ($R^2$ > 0.990). In addition, the assay was performed with commercial antibodies. This assay provides a convenient alternative to conventional, laborious sandwich immunoassays.

Sentence ion : Sentence Revision with Concept ion (문장추상화 : 개념추상화를 도입한 문장교열)

  • Kim, Gon;Yang, Jaegun;Bae, Jaehak;Lee, Jonghyuk
    • The KIPS Transactions:PartB
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    • v.11B no.5
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    • pp.563-572
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    • 2004
  • Sentence ion is a simplification of a sentence preserving its communicative function. It accomplishes sentence revision and concept ion simultaneously. Sentence revision is a method that resolves the discrepancy between human's thoughts and its expressed semantic in sentences. Concept ion is an expression of general ideas acquired from the common elements of concepts. Sentence ion selects the main constituents of given sentences and describes the upper concepts of them with detecting their semantic information. This enables sen fence revision and concept ion simultaneously. In this paper, a syntactic parser LGPI+ and an ontology OfN are utilized for sentence ion. Sentence abstracter SABOT makes use of LGPI+ and OfN. SABOT processes the result of parsing and selects the candidate words for sentence ion. This paper computes the sentence recall of the main sentences and the topic hit ratio of the selected sentences with the text understanding system using sentence ion. The sources are 58 paragraphs in 23 stories. As a result of it, the sentence recall is about .54 ~ 72% and the topic hit ratio is about 76 ~ 86%. This paper verified that sentence ion enables sentence revision that can select the topic sentences of a given text efficiently and concept ion that can improve the depth of text understanding.