• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제20권2호
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• pp.130-133
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• 2017

Noroviruses have been recognized as the leading cause of epidemic and sporadic gastroenteritis since the advent of molecular diagnostic technique. They have been documented in 5-31% of pediatric patients hospitalized with gastroenteritis. Although norovirus gastroenteritis is typically mild and self-limited, it causes severe, but sometimes fatal, conditions in the vulnerable population such as immunocompromised patients, young children, and the elderly. Bowel perforation due to norovirus infection is rare. We report a case of small bowel perforation with norovirus gastroenteritis in the infant with Down syndrome during the hospitalization with pneumonia. Severe dehydration may cause bowel ischemia and could have triggered bowel perforation in this case. Physicians should be alert to the potential surgical complications followed by severe acute diarrhea, especially in high risk groups.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2004년도 춘계학술대회논문집
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• pp.601-606
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• 2004

This paper deals with friction-induced vibration of disc brake system under constant friction coefficient. A linear, lumped and distributed parameter model to represent the floating caliper disc brake system is proposed. The complex eigenvalues are used to investigate the dynamic stability and in order to verify simulations which are based on the theoretical model, the experimental modal test and the dynamometer test are performed. The comparison of experimental and theoretical results shows a good agreement and the analysis indicates that mode coupling due to friction force is responsible for disc brake squeal. And squeal type instability is investigated by using the parametric analysis. This indicates parameters which have influence on the propensity of brake squeal. This helped to validate the analysis model and establish confidence in the analysis results. Also they may be useful during system development or diagnostic analysis.

• KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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• 제5B권4호
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• pp.392-398
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• 2005

This paper presents technologies that have strategic importance in future motor drives. The underlying strategic issue for motor drives is maintaining cost while increasing certain dimensions of functionality. The dimensions of functionality which should increase include reliability and added value features such as providing continuous energy optimization, providing sensing of the driven system suitable for application specific diagnostic purposes, and providing continuously optimal thermal utilization of the capability of the drive. This paper will address each of these issues and discuss the technology status for each case, with a focus on research needed to fully deliver the needed functionality.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1992년도 추계학술대회
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• pp.89-92
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• 1992

The sensory nerve study is the important index to diagnosis peripheral neuromyotic disease. This paper discusses about the design of parameter - latency, amplitude, conduction velocity - measurement system in the sensory nerve. This system consists of three parts which are Main Control Unit(MCU), Stimulator, and external output unit. Also new measurement algorithms which is adaptive threshold method is presented in this paper. The designed system is controlled by MCU includes automatic detection algorithms and self-diagnostic functions.

• 한국소음진동공학회논문집
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• 제14권8호
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• pp.702-708
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• 2004

This paper deals with friction-induced vibration of disc brake system under constant friction coefficient. A linear, lumped and distributed parameter model to represent the floating caliper disc brake system is proposed. The complex eigenvalues are used to investigate the dynamic stability and in order to verify simulations which are based on the theoretical model, the experimental modal test and the dynamometer test are performed. The comparison of experimental and theoretical results shows a good agreement and the analysis indicates that mode coupling due to friction force is responsible for disc brake squeal. And squeal type Instability is Investigated by using the parametric analysis. This indicates parameters which have influence on the propensity of brake squeal. This helped to validate the analysis model and establish confidence in the analysis results. Also they may be useful during system development or diagnostic analysis.

• 천문학회지
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• 제34권4호
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• pp.297-299
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• 2001

We have constructed the foundations to a series of theoretical diagnostic methods to probe the jet phenomenon in young stars as observed at various optical forbidden lines. We calculate and model in a self-consistent manner the physical and radiative processes which arise within an inner disk-wind driven magneto centrifugally from the circumstellar accretion disk of a young sun-like star. Comparing with real data taken at high angular resolution, our approach will provide the basis of systematic diagnostics for jets and their related young stellar objects, to attest the emission mechanisms of such phenomena. This work can help bring first-principle theoretical predictions to confront actual multi-wavelength observations, and will bridge the link between many very sophiscated numerical simulations and observational data. Analysis methods discussed here are immediately applicable to new high-resolution data obtained with HST and Adaptic Optics.

• Smart Structures and Systems
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• 제5권2호
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• pp.139-152
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• 2009

Globally, civil infrastructures are deteriorating at an alarming rate caused by overuse, overloading, aging, damage or failure due to natural or man-made hazards. With such a vast network of deteriorating infrastructure, there is a growing interest in continuous monitoring technologies. In order to provide a true distributed sensor and control system for civil structures, we are developing a Structural Nervous System that mimics key attributes of a human nervous system. This nervous system is made up of building blocks that are designed based on mechanoreceptors as a fundamentally new approach for the development of a structural health monitoring and diagnostic system that utilizes the recently developed piezo-fibers capable of sensing and actuation. In particular, our research has been focused on producing a sensory nervous system for civil structures by using piezo-fibers as sensory receptors, nerve fibers, neuronal pools, and spinocervical tract to the nodal and central processing units. This paper presents up to date results of our research, including the design and analysis of the structural nervous system.

• Journal of the Optical Society of Korea
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• 제9권4호
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• pp.157-161
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• 2005

Medical infrared imaging is obtained by measuring the self-emitted infrared radiance from the human body. Infrared emission is related to surface temperature and temperature is one of the most important physiological parameters related to health. Though recent applications such as security identification and oriental medicine have provided new fields of biomedical applications, infrared thermography has had ups and downs in its usages in cancer detection. Some of the main difficulties include finding proper applications and efficient diagnostic algorithms. In this study, infrared thermal imaging was used to detect regional metastasis of breast cancer. Our measurements were done for 110 women. From 63 individuals of a Healthy Group and a Benign Breast Disease Group, we developed algorithms for differentiating malignant regional metastasis based on temperature difference and asymmetry of temperature distribution. Testing with 47 cancer patients, we achieved a positive predictive value of $87.5\%$ and a negative predictive value of $95.6\%$. The results were better than for mammogram examination. A proper analysis of infrared imaging proved to be a highly informative and sensitive method for differentiating regional cancer metastasis from normal regions.

• 대한방사성의약품학회지
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• 제1권2호
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• pp.98-103
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• 2015

Good manufacturing Practice (GMP) regulation for diagnostic and therapeutic radiopharmaceuticals was prepared at 2014. The mandatory GMP regulation becomes effective on $1^{st}$, July 2015,with two years of grace periods. Korean radiopharmaceuticals GMP regulation was consisted of quality management, personnel, premise and facility, documentation, production, quality control and self-audit and they have a very similar structure to European Union and PIC/S GMP regulation. Here, we describe detailed description of GMP regulation each part and application to radiopharmaceuticals production. And we also compare Korea, Japan and USA radiopharmaceuticals GMP regulation. GMP is a method to maintain quality of radiopharmaceuticals in daily production and it must be embedded on the manufacturing operation and management.

• Investigative Magnetic Resonance Imaging
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• 제23권1호
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• pp.17-25
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• 2019

We discuss recent advances in Gd-based $T_1$-weighted MR contrast agents for the mapping of cellular pH. The pH plays a critical role in various biological processes. During the past two decades, several MR contrast agents of strategic importance for pH-mapping have been developed. Some of these agents shed light on the pH fluctuation in the tumor microenvironment. A pH-responsive self-assembled contrast agent facilitates the visualization of tumor size as small as $3mm^3$. Optimization of various parameters is crucial for the development of pH-responsive contrast agents. In due course, the new contrast agents may provide significant insight into pH fluctuations in the human body.