• Title/Summary/Keyword: Selection and Evaluation

Search Result 2,287, Processing Time 0.033 seconds

Signatures of positive selection underlying beef production traits in Korean cattle breeds

  • Edea, Zewdu;Jung, Kyoung Sub;Shin, Sung-Sub;Yoo, Song-Won;Choi, Jae Won;Kim, Kwan-Suk
    • Journal of Animal Science and Technology
    • /
    • v.62 no.3
    • /
    • pp.293-305
    • /
    • 2020
  • The difference in the breeding programs and population history may have diversely shaped the genomes of Korean native cattle breeds. In the absence of phenotypic data, comparisons of breeds that have been subjected to different selective pressures can aid to identify genomic regions and genes controlling qualitative and complex traits. In this study to decipher genetic variation and identify evidence of divergent selection, 3 Korean cattle breeds were genotyped using the recently developed high-density GeneSeek Genomic Profiler F250 (GGP-F250) array. The three Korean cattle breeds clustered according to their coat color phenotypes and breeding programs. The Heugu breed reliably showed smaller effective population size at all generations considered. Across the autosomal chromosomes, 113 and 83 annotated genes were identified from Hanwoo-Chikso and Hanwoo-Heugu comparisons, respectively of which 16 genes were shared between the two pairwise comparisons. The most important signals of selection were detected on bovine chromosomes 14 (24.39-25.13 Mb) and 18 (13.34-15.07 Mb), containing genes related to body size, and coat color (XKR4, LYN, PLAG1, SDR16C5, TMEM68, CDH15, MC1R, and GALNS). Some of the candidate genes are also associated with meat quality traits (ACSF3, EIF2B1, BANP, APCDD1, and GALM) and harbor quantitative trait locus (QTL) for beef production traits. Further functional analysis revealed that the candidate genes (DBI, ACSF3, HINT2, GBA2, AGPAT5, SCAP, ELP6, APOB, and RBL1) were involved in gene ontology (GO) terms relevant to meat quality including fatty acid oxidation, biosynthesis, and lipid storage. Candidate genes previously known to affect beef production and quality traits could be used in the beef cattle selection strategies.

A strategic R&D resource allocation and project selection based on R&D policy and objectives (정책목표와 연계한 전략적 R&D 투자재원배분 및 연구과제 선정방안연구)

  • 서창교;박정우
    • Journal of the Korean Operations Research and Management Science Society
    • /
    • v.16 no.2
    • /
    • pp.61-61
    • /
    • 1991
  • We propose a strategic R&D resource allocation and project selection model based on national R&D policy and objectives. First, contributions to R&D policy and objectives for each R&D area are evaluated by using analytical hierarchy process (AHP). Second, fuzzy Delphi are proposed to estimate R&D budget for each R&D area. Then, a project selection grid is also introduced to implement two-phased evaluation for R&D project selection. We also discuss how to improve the consistency in AHP and how to reduce the pairwise comparison in AHP. The proposed model enables the decision makers to allocate R&D budget, and to evaluate and select the R&D proposals based on both the contribution to national R&D policy and objectives, and the size of each R&D area concurrently

A strategic R&D resource allocation and project selection based on R&D policy and objectives. (정책목표와 연계한 전략적 R&D 투자재원배분 및 연구과제 선정방안연구)

  • 서창교;박정우
    • Korean Management Science Review
    • /
    • v.16 no.2
    • /
    • pp.61-77
    • /
    • 1999
  • We propose a strategic R&D resource allocation and project selection model based on national R&D policy and objectives. First, contributions to R&D policy and objectives for each R&D area are evaluated by using analytical hierarchy process (AHP). Second, fuzzy Delphi are proposed to estimate R&D budget for each R&D area. Then, a project selection grid is also introduced to implement two-phased evaluation for R&D project selection. We also discuss how to improve the consistency in AHP and how to reduce the pairwise comparison in AHP. The proposed model enables the decision makers to allocate R&D budget, and to evaluate and select the R&D proposals based on both the contribution to national R&D policy and objectives, and the size of each R&D area concurrently.

  • PDF

A study on the Economic Evaluation of Trunk using Teletraffic (통화량을 이용한 중계선의 경제성 평가에 관한 연구)

  • Yoo, Tae-Yol;Kim, Jae-Yeol;Lee, Sang-Il
    • Proceedings of the KIEE Conference
    • /
    • 1987.07b
    • /
    • pp.889-893
    • /
    • 1987
  • This paper suggests a model for the economic evaluation and the selection of alternatives using teletraffic. Economic evaluation is analyzed by the comparison of revenue loss which happens without trunk extension and additional revenue which results from trunk extension. Simulation technique is used as a methodology to apply economic evaluation to telephone system. The study results will provide a support in a optimal decision about investment strategies.

  • PDF

A Study on the Deterministic Evaluation Method of R&D Project in Food Industry (식품산업 연구개발의 결정론적 평가방법에 관한 연구)

  • 이종만;이근희
    • Journal of Korean Society of Industrial and Systems Engineering
    • /
    • v.14 no.23
    • /
    • pp.57-64
    • /
    • 1991
  • The preliminary, advanced and final evaluation of R&D project is essential in order to reduce loss of resource and opportunity and to minimize uncertainty resulting from optimal selection and efficient progress of R&D project. This thesis examined characteristics of deterministic evaluation, economical evaluation, and OR-approach evaluation as theoretical methodology of evaluation of R&D project applicable to food industry in Korea by using scoring method, one of deterministic evaluations. In addition, this thesis divided the evaluation factors for preliminary evaluation of R&D project into 5 groups and 30 factors on basis of the environment of domestic companies and set up the standard of each evaluation factors and contains marking-selecting way. But, generally, the evaluation model by this thesis, as the conditions of the business company environment are different to each other, contents to be set up evaluation factors, evaluation standard and decision method conforming to each the environment of the business companies with referring to as one standard of evaluation project for selecting R&D project.

  • PDF

Evaluation and Selection of Potential Parents Based on Selection Indices and Isozyme Variability in Silkworm, Bombyx mori, L.

  • Moorthy S.M.;Das S.K.;Rao, P.R.T.;Urs S. Rao,;Sarkar A.
    • International Journal of Industrial Entomology and Biomaterials
    • /
    • v.14 no.1
    • /
    • pp.1-7
    • /
    • 2007
  • In order to find out the appropriate parents for the breeding programme, twelve bivoltine and three multivoltine silkworm breeds were evaluated on the basis of multivariate selection index and isozyme analysis. Of which, four [CSR2, D6 (P), SK3, SK4] bivoltine and two multivoltine (Nistari, Cambodge) breeds were selected and breeding initiated to develop higher survival bivoltine silkworm breed suitable for tropical conditions. Among two isozyme (Esterase and acid phosphatase) analyzed, only esterase exhibited polymorphism among the bivoltine breeds. No polymorphism was observed among multivoltine in respect of esterase as well as acid phosphatase.

Simple and Rapid Evaluation System for Endosulfan Toxicity and Selection of Endosulfan Detoxifying Microorganism Based on Lumbricus rubellus (Lumbricus rubellus를 이용한 endosulfan의 간편, 신속 독성 평가 및 endosulfan 분해 미생물의 선별)

  • Sohn Ho-Yong;Kim Hong-Ju;Kum Eun-Joo;Lee Jung-Bok;Kwon Gi-Seok
    • Journal of Life Science
    • /
    • v.16 no.1
    • /
    • pp.108-113
    • /
    • 2006
  • To compensate the problems of chemical assay in detoxification of recalcitrant and a practical approach in selection of bioremediation bacteria, a simple and rapid toxicity evaluation system was constructed based on Lumbricus rubellus. Long term-culture and specific equipment are not necessary, and semi-quantitative analysis of toxicity at sub-lethal concentration is possible by measuring of dose-dependent increased yellowish secreted compounds. When the toxicity of endosulfan, its metabolites and structurally related chemicals were measured for 24 h, the results were coincided with previous reports. Toxicity was found in endosulfan, endosulfan sulfate, aldrin, and dieldrin, respectively. Rapid and economic selection of endosulfan-detoxifying bacteria was possible using our system. Klebsiella pneumoniae KE-1, K. oxytoca KE-8 and Pseudomonas sp. KS-2P, reported endosulfan degrading bacteria, ameliorated the endosulfan toxicity, whereas E. coli, B. subtilis and other bacteria failed to protect the toxicity of endosulfan in L. rubellus. Our results suggest that the constructed system is useful to selection of microorganism as well as toxicity evaluation against toxic recalcitrants.

AHP-Based Evaluation Model for Optimal Selection Process of Patching Materials for Concrete Repair: Focused on Quantitative Requirements

  • Do, Jeong-Yun;Kim, Doo-Kie
    • International Journal of Concrete Structures and Materials
    • /
    • v.6 no.2
    • /
    • pp.87-100
    • /
    • 2012
  • The process of selecting a repair material is a typical one of multi-criteria decision-making (MCDM) problems. In this study Analytical Hierarch Process was applied to solve this MCDM problem. Many factors affecting a process to select an optimal repair material can be classified into quantitative and qualitative requirements and this study handled only quantitative items. Quantitative requirements in the optimal selection model for repair material were divided into two parts, namely, the required chemical performance and the required physical performance. The former is composed of alkali-resistance, chloride permeability and electrical resistivity. The latter is composed of compressive strength, tensile strength, adhesive strength, drying shrinkage, elasticity and thermal expansion. The result of the study shows that this method is the useful and rational engineering approach in the problem concerning the selection of one out of many candidate repair materials even if this study was limited to repair material only for chloride-deteriorated concrete.

Applying a GIS to Solid and Hazardous Waste Disposal Site Selection (쓰레기매립장 부지선정을 위한 GIS 활용연구)

  • 김윤종;김원영;유일현;백종학;이현우;류중희
    • Korean Journal of Remote Sensing
    • /
    • v.6 no.2
    • /
    • pp.135-151
    • /
    • 1990
  • Solid and hazardous waste disposal site selection by using GIS(Geographic Information System) is the purpose of this study. The criteria of site selection are usually defined in accordance with geological, cultural and social characteristics. Unadequate adaptation of these criteria in a site selection may cause serious problem of water and soil pollution. The environmental information for extraction of these criteria consist of a lot of data : geology, geomorphology, hydrogeology, engineering geology, cultural and social information.... GIS could be easily applied to construct of this environmental information data base, and carry out cartography simulation using overlay mapping technique(polygon overlay). ARC/INFO(GIS system) was used for these studies, and AML(ARC/INFO Macro Language) in this system provided more variable and effective methods for cartography simulation. TM(Thematic Mapper) images were used for the evaluation of land cover/use in the studied area, by using ERDAS image processing system.

The Evaluation on the Execution Results of Middle School Educational Officials' Promotion Policy in Busan Metropolitan City (부산광역시 중등학교 교육공무원 승진정책의 집행결과 평가)

  • Kwon, Hyug-Dong
    • Journal of Fisheries and Marine Sciences Education
    • /
    • v.18 no.2
    • /
    • pp.98-107
    • /
    • 2006
  • This study has been made to see how much the execution results of the promotion policy for middle school teaching staffs succeeded for education development. The objects of the study are 70 physical education teachers in middle school in Busan, 2005, and the method is through questionnaires. The aim of the study is to grasp the propriety, the suitability, the effectiveness, the efficiency and the correspondence on the execution results of the promotion policy of middle schools' educational officials, and to refer to them at the policy. The conclusions are as follows:1. As to the propriety of promotion policy, it shows to have 65.8% support, so the aim selection proves not to be much unreasonable. 2. As to the suitability, it shows to have 52.5% support, so the selection of the policy ways for practicing the policy aim proves to be a little unsuitable. 3. As to the effectiveness, it shows to have 70.7% support, and the rate of support is the highest of the change factors of evaluation, so it proves to be very successful in the achievement of policy aim. 4. As to the efficiency, it shows to have 63.8% support, so the policy drive activity proves to be inefficient. 5. As to the correspondence, it shows to have 46.2% support, and it is the lowest mark of the change factors of evaluation. Therefore it proves that the favor-receiver, the physical education teachers have very low degree of good feeling.