• Asian-Australasian Journal of Animal Sciences
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• v.30 no.7
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• pp.912-919
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• 2017

Objective: Identification of the candidate genes that play key roles in phenotypic variations can provide new information about evolution and positive selection. Interleukin (IL)-32 is involved in many biological processes, however, its role for the immune response against various diseases in mammals is poorly understood. Therefore, the current investigation was performed for the better understanding of the molecular evolution and the positive selection of single nucleotide polymorphisms in IL-32 gene. Methods: By using fixation index ($F_{ST}$) based method, IL-32 (9375) gene was found to be outlier and under significant positive selection with the provisional combined allocation of mean heterozygosity and $F_{ST}$. Using nucleotide sequences of 11 mammalian species from National Center for Biotechnology Information database, the evolutionary selection of IL-32 gene was determined using Maximum likelihood model method, through four models (M1a, M2a, M7, and M8) in Codeml program of phylogenetic analysis by maximum liklihood. Results: IL-32 is detected under positive selection using the $F_{ST}$ simulations method. The phylogenetic tree revealed that goat IL-32 was in close resemblance with sheep IL-32. The coding nucleotide sequences were compared among 11 species and it was found that the goat IL-32 gene shared identity with sheep (96.54%), bison (91.97%), camel (58.39%), cat (56.59%), buffalo (56.50%), human (56.13%), dog (50.97%), horse (54.04%), and rabbit (53.41%) respectively. Conclusion: This study provides evidence for IL-32 gene as under significant positive selection in goat.

• Korean Journal of Poultry Science
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• v.40 no.3
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• pp.223-234
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• 2013

Poultry industry is abounding day by day as it engrosses less cost of investment per bird as compared to large animals. Poultry have the most copious genomic tool box amongst domestic animals for the detection of quantitative trait loci (QTL) and marker assisted selection (MAS). Use of multiple markers and least square techniques for mapping of QTL affecting quality and production traits in poultry is in vogue. Examples of genetic tests that are available to or used in industry programs are documented and classified into causative mutations (direct markers), linked markers in population-wide linkage disequilibrium (LD) with the QTL (LD markers), and linked markers in population wide equilibrium with the QTL (LE markers). Development of genome-wide SNP assays, role of 42 K, 60 K (Illumina) and 600 K (Affymetrix$^{(R)}$ Axim$^{(R)}$) SNP chip with next generation sequencing for identification of single nucleotide polymorphism (SNP) has been documented. Hybridization based, PCR based, DNA chip and sequencing based are the major segments of DNA markers which help in conducting of MAS in poultry. Economic index-marker assisted selection (EI-MAS) provides platform for simultaneous selection for production traits while giving due weightage to their marginal economic values by calculating predicted breeding value, using information on DNA markers which are normally associated with relevant QTL. Understanding of linkage equilibrium, linkage dis-equilibrium, relation between the markers and gene of interest are quite important for success of MAS. This kind of selection is the most useful tool in enhancing disease resistance by identifying candidate genes to improve the immune response. The application of marker assisted selection in selection procedures would help in improvement of economic traits in poultry.

• Journal of the Korean Statistical Society
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• v.30 no.3
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• pp.435-451
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• 2001

We describe a hierarchical bayesian model to analyze multinomial nonignorable nonresponse data. Using a Dirichlet and beta prior to model the cell probabilities, We develop a complete hierarchical bayesian analysis for multinomial proportions without making any algebraic approximation. Inference is sampling based and Markove chain Monte Carlo methods are used to perform the computations. We apply our method to the dta on body mass index(BMI) and show the model works reasonably well.

• Publications of The Korean Astronomical Society
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• v.12 no.1
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• pp.197-212
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• 1997

The general photometric, spectroscopic, and kinematic properties of the late type halo stars are investigated from a sample of known true halo stars. Halo stars are distributed in a lower left region of infrared (J-H) vs (H-K) color-color diagram, which is recomfirmed to be useful for selection of halo stars. They move with average velocity components of 9 km/sec, -14 km/sec, and 5 km/sec in U, V, and W directions respectively. They are distributed seperately from disk stars in a diagram of metallicity index, CaH1/TiO5 vs (R-I).

• Journal of the Chungcheong Mathematical Society
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• v.26 no.2
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• pp.343-349
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• 2013

The optimal portfolio selection problem under inflation risk is considered in this paper. There are three assets the economic agent can invest, which are a risk free bond, an index bond and a risky asset. By applying the martingale method, the optimal consumption rate and the optimal portfolios for each asset are obtained explicitly.

• Proceedings of the Korean Society for Quality Management Conference
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• 2006.11a
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• pp.275-282
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• 2006

급변하는 무한경쟁의 기업 상황에서 앞으로 기업의 생존을 결정할 새로운 시장과 신제품의 방향은 매우 중요한 전략결정이다. 블루오션 전략에서는 기업의 생존을 위해서 기존의 경쟁 시장에서 벗어나 개척되지 않은 새로운 시장으로의 진입을 강조하였다. 이러한 새로운 시장의 진입을 결정하는 방법으로 전략캠퍼스를 제시하였다. 그러나 전략캠퍼스는 기업에서 블루오션을 찾는 방법에서 한계를 갖고 있었다. 본 연구에서는 블루오션 전략의 전략캠퍼스를 대신하여 새로운 시장 또는 제품의 선정방법으로 Timko의 고객만족계수를 사용하였고 레드오션의 유지 전략을 잠재적 고객만족 개선 지수(PCSI Index)를 적용함으로써 고객의 소리를 통하여 블루오션의 접근하는 방법을 제시하였다.

• Atmosphere
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• v.16 no.4
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• pp.387-393
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• 2006

In this study, journal selection processes of the Science Citation Index (SCI) and the SCOPUS are investigated aiming at making the Journal of the Korean Meteorological Society (JKMS) an SCI journal. In addition, some characteristic features of the SCI journals in the field of atmospheric sciences published in Asian countries are examined. Some domestic journals in the related disciplines that are recently listed in the SCI and SCOPUS are also analyzed in terms of strategic approaches. Results of this study may provide fundamental strategic information in pursuing the JKMS to be listed in the SCI in the near future.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.17 no.31
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• pp.73-80
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• 1994

Sequentiality in decision making is an inherent characteristic of the R&D Process, Conceptual changes are noted during the Course of the Project which represent a continuous improvement in the quality of the data available during the various project stages. In this paper, Eight characteristic types of project evaluation models have been developed economic index models, portfolio models, decision theory models, risk analysis models, frontier models, scoring models, profile models and checklists. Each of these will be critically reviewed and appraised.

• Journal of the Korean Society for Library and Information Science
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• v.25
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• pp.51-82
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• 1993

Effective indexing systems are required to enhance the performance of full-text retrieval systems. The result of the analysis of index terms selected by human indexers without a newspaper thesaurus indicates that controlled indexing language is necessary for effective and consistent indexing of newspaper articles. In this paper, basic principles are established for keyword selection from Korean newspapers and significant problems identified in the process of developing a newspaper thesaurus are discussed in depth.

• Proceedings of the ESK Conference
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• 1997.10a
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• pp.346-350
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• 1997

Index of performance is dervied from consideration of movement times in routine selection tasks. The discrete movement task employed in this study consisted of moving a cursor from the home position to targets located 6.8, 15.9, 25.0, and 34.0 cm. The target widths were 2.3, 4.5, and 6.8cm. Eight subjects with nomovement disabilities took part in the experiment. Fitts' law is found to be applicable in this experiment.