• Title/Summary/Keyword: Screening effect

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Agglomeration of Toner Particles with Fatty Alcohol and Their Removal by Screening (고급알코올을 이용한 토너의 응집 및 스크리닝을 통한 제거 효과)

  • 허용성;이학래
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.36 no.2
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    • pp.24-32
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    • 2004
  • Toner used in xerographic printing process is hydrophobic powder with low surface energy. The toner ink film fused on paper surface can be efficiently detached from a fiber surface during pulping, but it does not fragment again into fine toner particles. Ink agglomerates that result have too large particle size to be deinked by flotation. The purpose of this study is to enhance toner agglomeration using 1-octadecanol for improving the toner removal by screening. The effect of pH, pulping temperature, and 1-octadecanol on toner agglomeration and removal by screening was investigated using image analysis methods. Results showed that the size of toner agglomerates increased substantially when pulping was carried out at high temperature under acidic condition. When toner agglomerates showed spherical shape, the particle removal efficiency of screening was improved.

General Pharmacological Properties of the New +/K+ ATPase Inhibitor DBM-819

  • Park, Woo-Kyu;Kong, Jae-Yang;Kim, Hyun-Jung;Lee, Dong-Ha;Lim, Hong;Cheon, Hyae-Gyeong
    • Biomolecules & Therapeutics
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    • v.10 no.1
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    • pp.19-24
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    • 2002
  • The effects of a newly synthesized $H^+/K^+$ ATPase inhibitor,1-(2-methyl-4-methoxypheny)-4-[(3-hy-droxypropyl)amino] -6-methyl-2,3-dihydropyrrolo (3,2-c) quinoline (DBM-819) , on the central nervous system, isolated smooth muscle, cardiovascular and digestive systems and renal function were investigated in various experimental animals. Oral administration of DBM-819 had no effect on the central nervous system except body temperature of mice slightly decreased at doses of 15 and 50 mg/kg. DBM-819 produced a moderate analgesic effect in acetic acid-induced writhing test in mice at 50 mg/kg (p.o.). In conscious rats, DBM-819 (15 and 50 mg/kg, p.o.) showed a slight increase in blood pressure and a small decrease in heart rate. DBM-819 had an significant effect on agonist-induced contraction of guinea pig ileum at $1.5{\times}10^{-5}g/ml.$ No significant effect of DBM-819 (5 and 15 mg/kg, i.p) on urinary volume or urinary excretion of $Na^+,\;K^+$ and Cl- was observed in rats. DBM-819 had no significant effect on intestinal transport of a semisolid meal in mice at 15 and 50 mg/kg (p.o.). These findings suggest that DBM-819 exerts no significant pharmacological effects on the central nervous system and renal function at 15 mg/kg (p.o.), but produces some effects on the smooth muscle and circulatory system.

Analysis on the Application of Railway Screening Effect in the Multi-conductor Line Solution of Induced Voltage to Telecommunication Lines by Electrified Traction System (전기철도에 의한 통신선 유도전압 다도체계산법상의 궤도효과 적용기술 분석)

  • Lee, Sang-Mu;Choi, Mun-Hwan;Cho, Pyoung-Dong
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.7B
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    • pp.601-607
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    • 2008
  • The induced voltages by AT power feeding system of electrified traction line to telecommunication line are calculated with the method of multi-conductor line solution in the CCITT Directives. There is a screening effect by railway line itself among various shielding factors against induction. It is the argue point whether the multi-conductor line solution contains the railway line effect since the calculation method does not show any expression about shielding factors. So this paper illuminates the mysterious question by reviewing the shielding factor principle on traction system, scrutinizing the Japanese bible about induction, analyzing the multi-conductor line solution itself, and comparing the result calculation considering the effect of railway screen. This paper concludes that multi-conductor line solution contains the screening effect of railway lines.

Effect of Gastric Cancer Screening on Patients with Gastric Cancer: A Nationwide Population-based Study (위암 환자에서 국가암검진의 효과)

  • Cho, Young Suk;Lee, Sang Hoon;So, Hyun Ju;Kim, Dong Wook;Choi, Yoon Jung;Jeon, Han Ho
    • Journal of Digestive Cancer Reports
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    • v.8 no.2
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    • pp.102-108
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    • 2020
  • Background: This study was performed to evaluate the effect of gastric cancer screening through analysis of screening-related data. Methods: We investigated claims data of gastric cancer from 2009 to 2015. We evaluated whether the screening was performed to prior to registration as patients with gastric cancer. The effect of gastric cancer screening was also analyzed by gender. Results: We collected total 196,293 patients with gastric cancer. 74% of them had previous experience of gastric cancer screening. In patients with screening, early gastric cancer was 33.4% and advanced gastric cancer was 17.3%. 22,548 (15.5%) patients were diagnosed with gastric cancer within 2 years after screening. In the case of patients without screening, early gastric cancer was 15.1% and advanced gastric cancer was 25.3%. In case of men, 76% of them confirmed gastric cancer through screening, and 70.2% of women confirmed the gastric cancer. In both men and women, the rate of early gastric cancer was higher among those with screening than those without screening. Conclusion: In this study, we were able to indirectly confirm the stage shift of gastric cancer screening. However, within 2 years after screening, not a few patients with gastric cancer were diagnosed. Therefore, more studies are warranted to in the future.

Effect of Screening on Variation in Cervical Cancer Survival by Socioeconomic Determinants - a Study from Rural South India

  • Thulaseedharan, Jissa Vinoda;Malila, Nea;Swaminathan, Rajaraman;Esmy, Pulikottil Okuru;Cherian, Mary;Hakama, Matti;Muwonge, Richard;Sankaranarayanan, Rengaswamy
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5237-5242
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    • 2015
  • Background: Socioeconomic factors are associated with screening in terms of reducing the risk of cervical cancer. This study aimed to clearly establish the effect of screening on variation in socio-economic factor-specific survival estimates. Materials and Methods: Survival estimates were calculated using the life table method for 165 women from the routine care control arm and 67 from the visual inspection with acetic acid screening arm diagnosed with cervical cancer during 2000-2006 in rural south India. Kaplan-Meier survival curves were plotted to compare the variation in survival by socioeconomic factors. Results: Whereas there was a significant variation in survival estimates of the different categories of age at diagnosis among the screen-detected cancers with women aged<50 years having an improved survival, no significant variation was noted among women diagnosed with cervical cancer from the control arm. Compared to the variation among the cancer cases detected in the unscreened control group, screening widened the variation in survival estimates by age and type of house, and reduced the variation by education. The direction of the magnitude of the survival estimates was reversed within the different categories of occupation, marital status and household income in the screen-detected cancer cases compared to control group cancer cases. Also, women diagnosed with stage 1 disease had a very good survival. Conclusions: Screening changed the pattern of survival by socio-economic factors. We found improved survival rates in screened women aged <50 years, with no formal education, manual workers and married women.

Screening Test of Selaginella tarmariscina for Liver Protective Effects in Primary Cultured Hepatocytes (일차 배양한 간세포에서의 권백의 간보호효과의 Screening Test)

  • Yoon, Soo-Hong;Lee, Ju-Young;Ha, Hun
    • Environmental Analysis Health and Toxicology
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    • v.11 no.3_4
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    • pp.65-68
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    • 1996
  • Selaginellae Herba has been used as folk medicine for antineoplastics, coagulants, antidotes and invigorants. To find an in vitro screening method for liver protective effect of Selaginellae Herba in benzo(a)pyrene intoxicated injury were examined in primary cultured rat hepatocytes. Using MTT assay, herba concentration showed dose dependently viability. The lowest concentration of benzo(a)pyrene giving cytotoxicity revealed around 50gM. The hepatoprotective effect of Selaginellae Herba in both water and chloroform extracts was also increased dose dependently.

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Effects of Agglomeration of Toner Particles with Fatty Alcohol on Flotation Deinking Efficiency (고급알코올에 의한 토너의 응집처리가 부유부상 탈묵효과에 미치는 영향)

  • 허용성;이학래
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.36 no.2
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    • pp.33-38
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    • 2004
  • Toner particles used in laser and xerographic printing process is fused on paper surface so strongly that they tend not to detach easily from the recylced paper surface during pulping. Furthermore, the removal efficiency of detached toner particles by conventional screening and flotation process has limitation due to the platy shape and large size of detached toner particles. It has been shown that the removal efficiency of toners in the screening process can be increased by agglomerating the toner particles with fatty alcohol. It is not possible, however, to remove small and platy toner particles by screening process. These small and platy toner particles should be removed by flotation process. In this study the effect of fatty alcohol that used for toner agglomeration on flotation efficiency has been examined. It was shown that flotation efficiency decreased when fatty alcohol was used most probably due to its effect of reducing hydrophobicity of toner particles.

Induction of Colonial Growth of the Cellulolytic Fungus, Genus Trichoderma (섬유소분해균인 Trichoderma의 群體生長의 유도에 관하여)

  • Park, Hee-Moon;Hong, Soon-Woo;Hah, Yung-Chil
    • Korean Journal of Microbiology
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    • v.22 no.3
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    • pp.143-150
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    • 1984
  • The effect of growth inhibitors on colonial growth of cellulolytic fungus, genus Trichoderma, was investigated to develop a method for the effective screening of various auxotrophs and hypercellulolytic strains. As the results, it was revealed that non-ionic detergents such as Sodium deoxycholate and Triton X-100 were the better ones as a growth inhibitor than Oxgall which has been used to restrict the colony size in genus Trichoderma. Each individual colony remained distinct on minimal plate supplemented with 0.05% Triton X-100 for as long as two or more weeks. The screening of 150 to 200 colonies simultaneous on a single plate was possible in the presence of Triton X-100. The effect of Triton X-100 on simultaneous screening was higher than that of Oxgall by a factor of two.

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Characterization of the KG1a Cell Line for Use in a Cell Migration Based Screening Assay

  • Bernhard O. Palsson;Karl francis;Lee, Gyun-Min
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.7 no.3
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    • pp.178-184
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    • 2002
  • High-throughput screening has become a popular method used to identify new “leads”for potentially therapeutic compounds. Further screening of these lead compounds is typically done with secondary assays which may utilize living, functioning cells as screening tools. A problem (or benefit) with these cell-based assays is that living cells are very sensitive to their environment. We have been interested in the process of stem cell migration and how it relates to the cellular therapy of bone marrow transplantation. In this study we describe a secondary, cell-based assay for screening the effects of various in-vitro conditions on Immature Hematopoietic Cell (IHC) migration. Our results have revealed many subtle factors, such as the cell's adhesive characteristics, or the effect of a culture's growth phase, that need to be accounted for in a screening protocol. Finally, we show that exponentially glowing KG1a cells (a human IHC cell line) were 10 times more motile than those in the lag or stationary phases. These data strongly suggest that KG1a cells secrete a chemokinetic factor during the exponential growth phase of a culture.