• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.10a
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• pp.981-984
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• 2014

Volumetric measurement of hippocampus using IBASPM, the 20's normal adults 10 people's brain images were acquired in order to assess the changes according to the type of the Atlas. Images was obtained using MPRAGE of a 3-D gradient echo pulse sequence on Head matrix coil of 1.5T MRI system. The results of Paired t-test using obtained volume of hippocampus depending on the type of the Atlas, Atlas69-Altas84, Atlas69-Atlas116(p=0.729, 0.729) in the left hippocampus and Atlas69-Atlas84, Atlas69-Atlas116(p=0.219, 0.219) in right hippocampal formation were no significant differences but in the area except this, there was significant difference(p=0.000). The volume of the hippocampus using Atlas84 and Atlas116, represented the same value and there was no significant difference. In the image analysis using the overlay of atlas image and original image, Atlas71 could be found that the area of hippocampus did mismatch. In the case of atlas used in this study, because it has been developed by the westerners, there are differences between brain of asian. It would be needed to development of new Atlas for high accuracy measurement of the volume of hippocampus.

• Resources Recycling
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• v.28 no.4
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• pp.15-22
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• 2019

Coal combustion products are generated during coal combustion and can be grouped into fly ash and bottom ash depending on collection methods. Fly ash and bottom ash can be recycled for various purposes based on their characteristics. Australia is the fourth largest coal production country in the world and reuses coal ash as cement, concrete, mine filler, and agricultural soil amendment. When fly ash is used as a supplement for cement and concrete, strength of the cement and the durability of the concrete can be improved. Use of coal combustion product for mine backfill stabilizes underground mine voids and stores a large amount of coal ash in the voids. Because of alkalinity of coal combustion products, it can neutralize acid mine drainage when used for mine backfill. In addition, it can be used as an agricultural soil amendment to improve acidity and physical properties of the soil and to supply plant nutrients. Recycling of fly ash in Australia will be further expanded because of its low trace element contents that can be toxic to plants and low radioactive element contents existing within soil background concentrations. The characteristics of coal combustion products are related to the characteristics of the coal used for combustion, and since Korea imports coal from Australia, Korean coal combustion products also can be recycled for various purposes.

• Journal of the Korean Geotechnical Society
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• v.35 no.9
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• pp.5-13
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• 2019

The soil-water characteristic curve (SWCC) plays an important role in determining the soil suction parameters required to predict the seepage or shear behaviors of unsaturated soils. In addition, path dependency of the SWCC affects the mechanical and hydrologic behaviors. In general, there is a disadvantage that it takes a long time to measure both the drying and wetting paths of the SWCC by a stepwise pressurization method. Thus, the continuous pressurization method as an improved testing method for the SWCC was suggested, and the testing time for two paths of the SWCC was significantly shorter than the conventional methods. For the applicability evaluation of this method, the results of the SWCC obtained by the stepwise pressurization method and the evaporation method in this study were compared to the result obtained from this method. As a result, it was found that the difference among three methods was negligible, and the testing time of the continuous pressurization method was greatly decreased. Therefore, it can be said that it is possible to quickly and accurately measure the SWCC under various conditions by the continuous pressurization method.

• Journal of Radiation Protection and Research
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• v.44 no.3
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• pp.103-109
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• 2019

Background: Four-dimensional computed tomographic (4DCT) images are increasingly used in clinic with the growing need to account for the respiratory motion of the patient during radiation treatment. One of the reason s that makes the dose evaluation using 4DCT inaccurate is a change of the patient respiration during the treatment session, i.e., intrafractional uncertainty. Especially, when the amplitude of the patient respiration is greater than the respiration range during the 4DCT acquisition, such an organ motion from the larger respiration is difficult to be represented with the 4DCT. In this paper, the method to generate images expecting the organ motion from a respiration with extended amplitude was proposed and examined. Materials and Methods: We propose a method to generate extra-phase images from a given set of the 4DCT images using deformable image registration (DIR) and linear extrapolation. Deformation vector fields (DVF) are calculated from the given set of images, then extrapolated according to respiratory surrogate. The extra-phase images are generated by applying the extrapolated DVFs to the existing 4DCT images. The proposed method was tested with the 4DCT of a physical 4D phantom. Results and Discussion: The tumor position in the generated extra-phase image was in a good agreement with that in the gold-standard image which is separately acquired, using the same 4DCT machine, with a larger range of respiration. It was also found that we can generate the best quality extra-phase image by using the maximum inhalation phase (T0) and maximum exhalation phase (T50) images for extrapolation. Conclusion: In the present study, a method to construct extra-phase images that represent expanded respiratory motion of the patient has been proposed and tested. The movement of organs from a larger respiration amplitude can be predicted by the proposed method. We believe the method may be utilized for realistic simulation of radiation therapy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.9
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• pp.93-102
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• 2019

This study examined the nurse's emotional exhaustion and influencing factors, and the relationship between emotional burnout and hospital nursing workload using multilevel logistic regression analysis. The study subjects were 3,083 nurses of 65 hospitals, who participated in the training conducted by the Healthcare Industry Trade Union in 2010 and responded to the questionnaire. First, 71.6% of nurses experienced emotional exhaustion, and the average score of emotional exhaustion was 33.53. Second, the 'non - nursing work experience' showed a significant effect on emotional exhaustion. Third, the 'sufficient nursing staff' variable increased the emotional exhaustion. Fourth, the nursing grades were correlated significantly with emotional exhaustion compared to those with more than four beds per nurse. Fifth, in the case of working in the internal ward, the shorter the clinical career, the higher the emotional exhaustion. In other words, higher emotional exhaustion was associated with more nursing work experience, more perceived insufficient nursing staff, more nurses per bed, the department of internal medicine, and a shorter clinical career.

• Journal of Digital Convergence
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• v.17 no.8
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• pp.453-463
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• 2019

The purpose of this study was to investigate one-person household its health-related quality of life(HRQOL) using data from the seventh Korea national health and nutrition examination survey(KNHANES Ⅶ-2) 2017. The subjects were 301. The data were analyzed by frequency, descriptive analysis and linear regression analysis using SPSS complex samples Win 25 program. The HRQOL score was 0.92, and 2.5% of the subjects in the pain and discomfort area had severe problems. HRQOL related to the subject was 0.034, 0.039, and 0.031, respectively, when the household income level was lower, the education level was lower than elementary school graduates, and if they did not drink at present. HRQOL was 0.072, 0.065, 0.103, and 0.040 in perceived health status good or moderate, the absence of activity limitation and arthritis, was explained 43.1%. There is a need to develop interdisciplinary approaches with great interest in improving the one-person households HRQOL.

• Therapeutic Science for Rehabilitation
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• v.8 no.3
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• pp.83-95
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• 2019

Objective: The purpose of this study was to investigate the effects of the Power Card strategy on the receptive vocabulary and expressive vocabulary in children with autism spectrum disorders. Method: Three children with autism spectrum disorder were selected for this study and the power card strategy language intervention was applied, using a multiple baseline design across individuals. The target vocabulary was selected by examining the individual preferred characters. Power cards were constructed, and intervention was applied to improve the receptive vocabulary and expressive vocabulary through the baseline stage, intervention, and maintenance. Result: The application of the power card strategy showed that the acquisition rate of receptive vocabulary in children with autism spectrum disorder was increased, and expressive vocabulary acquisition rate was also improved. Conclusion: During the intervention period using the power card strategy, the children's target receptive vocabulary and expressive vocabulary acquisition rates improved, and the acquisition rate was maintained, even after the intervention. This suggests that the power card strategy is effective in improving the vocabulary of autistic children with disabilities, of school age.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.18 no.5
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• pp.100-111
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• 2019

The existing selected station analysis (SSA) method analyzes the link transfer mode data between origin and destination of individuals passing through stations from a microscopic standpoint. As such, existing SSA is insufficient as it uses integrated analysis using macroscopic data such as subway lines. This research builds a line chain OD based on path search of individual passenger's movement through the subway, and explores means to utilize the findings. First, a method is proposed that searches the traversed subway path from the linked passage modes that the passenger uses and applies the results to SSA line analysis. Compared to the existing SSA, this method provides for analysis of commonly conflicting features such as the line on which the station is passed, and the stations included on the line thanks to the presence of complete information of the individual passenger's traversed path. It also allows for integrated observation of the line chain OD that approaches a certain station. For enhanced understanding, Seoul Metro Line 9 is used as a case study to demonstrate the integrated formulation concept of line chain OD centered around a certain station as well as the macroscopic features of the traversed path that approaches stations included on the line.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.18 no.5
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• pp.91-99
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• 2019

Existing node-to-node based optimal path searching is built on the assumption that all destination nodes can be arrived at from an origin node. However, the recent appearance of the adaptive path search algorithm has meant that the optimal path solution cannot be derived in node-to-node path search. In order to reflect transportation data at the links in real-time, the necessity of the node-to-link (or link-to-node; NL) problem is being recognized. This research assumes existence of a network with link-label and non-additive path costs as a solution to the node-to-link optimal path problem. At the intersections in which the link-label has a turn penalty, the network retains its shape. Non-additive path cost requires that M-similar paths be enumerated so that the ideal path can be ascertained. In this, the research proposes direction deletion and turn restriction so that regulation of the loop in the link-label entry-link-based network transformation method will ensure that an optimal solution is derived up until the final link. Using this method on a case study shows that the proposed method derives the optimal solution through learning. The research concludes by bringing to light the necessity of verification in large-scale networks.

• Biomolecules & Therapeutics
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• v.27 no.4
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• pp.414-422
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• 2019

There is accumulating evidence that microRNAs are emerging as pivotal regulators in the development and progression of neuropathic pain. MicroRNA-15a/16 (miR-15a/16) have been reported to play an important role in various diseases and inflammation response processes. However, whether miR-15a/16 participates in the regulation of neuroinflammation and neuropathic pain development remains unknown. In this study, we established a mouse model of neuropathic pain by chronic constriction injury (CCI) of the sciatic nerves. Our results showed that both miR-15a and miR-16 expression was significantly upregulated in the spinal cord of CCI rats. Downregulation of the expression of miR-15a and miR-16 by intrathecal injection of a specific inhibitor significantly attenuated the mechanical allodynia and thermal hyperalgesia of CCI rats. Furthermore, inhibition of miR-15a and miR-16 downregulated the expression of interleukin-$1{\beta}$ and tumor-necrosis factor-${\alpha}$ in the spinal cord of CCI rats. Bioinformatic analysis predicted that G protein-coupled receptor kinase 2 (GRK2), an important regulator in neuropathic pain and inflammation, was a potential target gene of miR-15a and miR-16. Inhibition of miR-15a and miR-16 markedly increased the expression of GRK2 while downregulating the activation of p38 mitogen-activated protein kinase and $NF-{\kappa}B$ in CCI rats. Notably, the silencing of GRK2 significantly reversed the inhibitory effects of miR-15a/16 inhibition in neuropathic pain. In conclusion, our results suggest that inhibition of miR-15a/16 expression alleviates neuropathic pain development by targeting GRK2. These findings provide novel insights into the molecular pathogenesis of neuropathic pain and suggest potential therapeutic targets for preventing neuropathic pain development.