• Korean Journal of Health Education and Promotion
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• v.21 no.3
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• pp.195-211
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• 2004

Stress is a primary health promotion issue in worksite research because psychological distress is closely related not only to workers' health status but also to their job performance. This study identified the significant health behaviors affecting workers' job-related stress in Korean manufacturing industry with the national survey data conducted by the Korean Occupational Safety and Health Agency in 2003. A total of 7,818 factory workers in 1,562 manufacturing companies participated in the Korean nation-wide occupational health survey and 3,390 workers answered that they had any stressors in their workplace among the 7,818 workers finally participated in the analysis. Participants were selected by the stratified proportional sampling process by manufacturing industry classification, company size, and company locations (8 metropolitan and 8 non-metropolitan regions) in Korea. Trained interviewers visited the target companies and interviewed the factory workers randomly selected in each company. Smoking, drinking, weight control, exercise, sleeping, break time at work, and perceived fatigue were included in the health behavior construct. Stress symptoms was consisted of physical and psychological stress with 8 items. All survey responses were anonymously coded into the SPSS statistical program and testified using stepwise multiple regression analysis. Male workers were 73.5% and the 30s were 40.0% among the age groups. The married and the high school graduate were majority with 52.1% and 61.8% each. Current smokers were 44.7% and More than 50% of the participants drank alcohol sometimes. No exercise group was 59.3% and the participants who dissatisfied with their daily sleeping hours were 43.5%. In t-test and analysis of variance, the significant general characteristics associated with physical and psychological job stress were young age (p<0.001), single marital status (p<0.001), and short working period at the present company (p<0.001). The health behaviors related to physical job stress were current smoking, weight change during the past one year (p<0.001), weight control effort (p<0.001), exercise (p<0.001), daily sleeping dissatisfaction (p<0.001), break time, and perceived fatigue (p<0.001). All 10 health behavior factors were significantly associated with psychological job stress (p<0.05). Weight change, weight control effort, exercise, daily sleeping dissatisfaction, little break at work, and high perceived fatigue were significant factors affecting job stress. Daily sleeping dissatisfaction, little break at work, little exercise, weight change for the past one year and young age were selected as the significant health behavior and general factors affecting physical job stress symptoms in stepwise multiple regression analysis. The five factors explained 18.9% of the physical stress score variance. Six factors were selected as the significant health behaviors affecting psychological job stress: daily sleeping dissatisfaction, little exercise, frequent drinking alcohol, high perceived fatigue, little break at work, and little weight control effort. The six factors explained 10.6% of the psychological stress score variance.

• The Journal of Advanced Prosthodontics
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• v.3 no.3
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• pp.161-165
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• 2011

PURPOSE. This randomized clinical trial was conducted to assess the safety and effectiveness of the ErhBMP-2 in alveolar bone regeneration as well as preservation of the ${\beta}$-TCP bone graft material that contains ErhBMP-2. MATERIALS AND METHODS. This study involved 72 patients at the 3 study centers. The patients, who were divided into 2 groups: the experiment group who had ErhBMP-2 coated TCP/HA and the control group who had TCP/HA graft material alone transplanted immediately after tooth extraction. CT was taken before and 3 months after the transplantation and healing status was compared between the two groups. The efficacy endpoints that were used to measure the degree of bone induction included alveolar bone height and 3 measurements of bone width. The paired t test was used to determine the significance of the changes (P<.05). RESULTS. Changes in alveolar bone height were $-1.087{\pm}1.413$ mm in the control group and $-.059{\pm}0.960$ mm in the experimental group (P<.01). At 25% extraction socket length [ESL], the changes were $0.006{\pm}1.149$ mm in the control group and $1.279{\pm}1.387$ mm in the experimental group. At 50% ESL, the changes were $0.542{\pm}1.157$ mm and $1.239{\pm}1.249$ mm, respectively (P<.01 for 25% ESL, and P<.05 for 50% ESL). During the experiment, no adverse reactions to the graft material were observed. CONCLUSION. ErhBMP-2 coated ${\beta}$-TCP/HA were found to be more effective in preserving alveolar bone than conventional ${\beta}$-TCP/HA alloplastic bone graft materials.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.2
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• pp.285-294
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• 2011

The abatement of methane emission from ruminants is an important global issue due to its contribution to greenhouse gas with carbon dioxide. Methane is generated in the rumen by methanogens (archaea) that utilize metabolic hydrogen ($H_2$) to reduce carbon dioxide, and is a significant electron sink in the rumen ecosystem. Therefore, the competition for hydrogen used for methanogenesis with alternative reductions of rumen microbes should be an effective option to reduce rumen methanogenesis. Some methanogens parasitically survive on the surface of ciliate protozoa, so that defaunation or decrease in protozoa number might contribute to abate methanogenesis. The most important issue for mitigation of rumen methanogenesis with manipulators is to secure safety for animals and their products and the environment. In this respect, prophylactic effects of probiotics, prebiotics and miscellaneous compounds to mitigate rumen methanogenesis have been developed instead of antibiotics, ionophores such as monensin, and lasalocid in Japan. Nitrate suppresses rumen methanogenesis by its reducing reaction in the rumen. However, excess intake of nitrate causes intoxication due to nitrite accumulation, which induces methemoglobinemia. The nitrite accumulation is attributed to a relatively higher rate of nitrate reduction to nitrite than nitrite to ammonia via nitroxyl and hydroxylamine. The in vitro and in vivo trials have been conducted to clarify the prophylactic effects of L-cysteine, some strains of lactic acid bacteria and yeast and/or ${\beta}$1-4 galactooligosaccharide on nitrate-nitrite intoxication and methanogenesis. The administration of nitrate with ${\beta}$1-4 galacto-oligosaccharide, Candida kefyr, and Lactococcus lactis subsp. lactis were suggested to possibly control rumen methanogenesis and prevent nitrite formation in the rumen. For prebiotics, nisin which is a bacteriocin produced by Lactococcus lactis subsp. lactis has been demonstrated to abate rumen methanogenesis in the same manner as monensin. A protein resistant anti-microbe (PRA) has been isolated from Lactobacillus plantarum as a manipulator to mitigate rumen methanogenesis. Recently, hydrogen peroxide was identified as a part of the manipulating effect of PRA on rumen methanogenesis. The suppressing effects of secondary metabolites from plants such as saponin and tannin on rumen methanogenesis have been examined. Especially, yucca schidigera extract, sarsaponin (steroidal glycosides), can suppress rumen methanogenesis thereby improving protein utilization efficiency. The cashew nutshell liquid (CNSL), or cashew shell oil, which is a natural resin found in the honeycomb structure of the cashew nutshell has been found to mitigate rumen methanogenesis. In an attempt to seek manipulators in the section on methane belching from ruminants, the arrangement of an inventory of mitigation technologies available for the Clean Development Mechanism (CDM) and Joint Implementation (JI) in the Kyoto mechanism has been advancing to target ruminant livestock in Asian and Pacific regions.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.6089-6092
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• 2015

Background: The prevalence of metronidazole-resistant H. pylori is almost 50% in Thailand which severely limits the use of this drug for eradication therapy. The aims of this study were to evaluate the efficacy and safety profiles of 7-day bismuth-based quadruple therapy including metronidazole as an initial treatment for H. pylori infection in a high metronidazole resistance area. Materials and Methods: This study was performed at Thammasat University Hospital and King Chulalongkorn Memorial Hospital during January 2009 to October 2010. Patients with non-ulcer dyspepsia (NUD) with active H. pylori infection were assigned to receive seven days of quadruple therapy (pantoprazole 40 mg bid, bismuth subsalicylate 1,048 mg bid, amoxicillin 1 gm bid and metronidazole 400 mg tid). H. pylori infection was defined as positive H. pylori culture or two positive tests (rapid urease test and histology). Antibiotic susceptibility test for metronidazole by Epsilometer test (E-test) was performed in all positive cultures. At least four weeks after treatment, $^{13}C$ urea breath test ($^{13}C-UBT$) was performed to confirm H. pylori eradication. Results: A total of 114 patients were enrolled in this study, 50 males and 64 females with a mean age of 49.8 years. All 114 patients had a diagnosis of NUD. Overall eradication as confirmed by negative $^{13}C-UBT$ was achieved in 94 out of 114 patients (82.5%). 44 patients had positive cultures and success for E-test. In vitro metronidazole resistance was observed in 22/44 (50%) patients. Eradication rate in patients with metronidazole resistant strains was 16/22 (72.7%) and 20/22 (90.1%) with metronidazole sensitive strains (72.7% vs 90.1%, p-value=0.12; OR=3.75 [95%CI=0.6-31.5]). Minor adverse reactions included nausea, bitter taste, diarrhea and black stools but none of the patients dropped out from the study. Conclusions: Initial treatment with 7-day bismuth-based quadruple therapy including metronidazole, amoxycillin and pantoprazole is highly effective and well tolerated for metronidazole-sensitive H. pylori infections. However, the efficacy markedly decline with metronidazole resistance. Longer duration of this regimen might be required to improve the eradication rate and larger multi-center studies are needed to confirm this hypothesis.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3435-3442
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• 2015

Objective : To provide background information for strengthening cervical cancer prevention in the Pacific by mapping current human papillomavirus (HPV) vaccination and cervical cancer screening practices, as well as intent and barriers to the introduction and maintenance of national HPV vaccination programmes in the region. Materials and Methods: A cross-sectional questionnaire-based survey among ministry of health officials from 21 Pacific Island countries and territories (n=21). Results: Cervical cancer prevention was rated as highly important, but implementation of prevention programs were insufficient, with only two of 21 countries and territories having achieved coverage of cervical cancer screening above 40%. Ten of 21 countries and territories had included HPV vaccination in their immunization schedule, but only two countries reported coverage of HPV vaccination above 60% among the targeted population. Key barriers to the introduction and continuation of HPV vaccination were reported to be: (i) Lack of sustainable financing for HPV vaccine programs; (ii) Lack of visible government endorsement; (iii) Critical public perception of the value and safety of the HPV vaccine; and (iv) Lack of clear guidelines and policies for HPV vaccination. Conclusion: Current practices to prevent cervical cancer in the Pacific Region do not match the high burden of disease from cervical cancer. A regional approach, including reducing vaccine prices by bulk purchase of vaccine, technical support for implementation of prevention programs, operational research and advocacy could strengthen political momentum for cervical cancer prevention and avoid risking the lives of many women in the Pacific.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2369-2378
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• 2012

Objectives: To assess knowledge of HPV and attitudes towards HPV vaccination among the general female population, government officials, and healthcare providers in China to assist the development of an effective national HPV vaccination program. Methods: A cross-sectional epidemiologic survey was conducted across 21 urban and rural sites in China using a short questionnaire. 763 government officials, 760 healthcare providers, and 11,681 women aged 15-59 years were included in the final analysis. Data were analyzed using standard descriptive statistics and logistic regression. Results: Knowledge of HPV among the general female population was low; only 24% had heard of HPV. Less than 20% of healthcare providers recognized sexually na$\ddot{i}$ve women as the most appropriate population for HPV vaccination. There was high acceptance of the HPV vaccine for all categories of respondents. Only 6% of women were willing to pay more than US $300 for the vaccine. Conclusions: Aggressive education is necessary to increase knowledge of HPV and its vaccine. Further proof of vaccine safety and efficacy and government subsidies combined with increased awareness could facilitate development and implementation of HPV vaccination in China.

• The Journal of the Korea Contents Association
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• v.16 no.7
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• pp.651-658
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• 2016

As three sides of Korea are surrounded by the sea and it is geographically located at an intersect point for continental and maritime climate, the climate crisis and global warming factors that lead to large-scale natural disasters such as typhoons, floods, and tsunami as well as disasters and damage to humans are increasing due to rapid urbanization and industrialization. Therefore, this study measured the ability of people to cope with disaster in students studying emergency rescue who will play a central role in safety and casualty control in disaster areas in order to figure out the factors that will influence their overall ability. As a result, the following things were discovered: Those who had the experience of listening to information on how to cope in a disaster scored significantly higher in disaster coping scores than those who did not. In comparison with subjects who responded that they were not satisfied with their emergency rescue training at school, those who responded that they were satisfied with their education scored significantly higher in their disaster coping scores. In comparison with subjects who responded negatively to the questions on experience in emergency rescue training as an extracurricular program, those who responded affirmatively to the questions were evaluated as significantly higher in their disaster coping scores. This study suggests that specific strategies can be taken and are needed to improve the ability to cope with disasters in students who are studying emergency rescue.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.639-645
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• 2018

This paper is intended to develop a decision model that can be applied to autonomous vehicles and autonomous mobile vehicles. The developed module has an independent configuration for application in various driving environments and is based on a platform for organically operating them. Each module is studied for decision making on lane changes and for securing safety through reinforcement learning using a deep learning technique. The autonomous mobile moving body operating to change the driving state has a characteristic where the next operation of the mobile body can be determined only if the definition of the speed determination model (according to its functions) and the lane change decision are correctly preceded. Also, if all the moving bodies traveling on a general road are equipped with an autonomous driving function, it is difficult to consider the factors that may occur between each mobile unit from unexpected environmental changes. Considering these factors, we applied the decision model to the platform and studied the lane change decision system for implementation of the platform. We studied the decision model using a modular learning method to reduce system complexity, to reduce the learning time, and to consider model replacement.

• Journal of Navigation and Port Research
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• v.39 no.1
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• pp.29-35
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• 2015

As the numbers of users of domestic passenger ships increased up to 14.5 millions at 2012, the numbers of ships accidents also increased as 2 times than ever. It will be very important to develop technologies related with safety design for onboard passengers and disclose the potential problems. This study performed consciousness survey on ordinary peoples' way finding who have not got any regular anti-disaster training, to develop evacuation models for evacuation feasibility studies. Followings are the results answered by 83 participants for 33 way finding questions. Respondents selected right ways more than 6~18% for 2 ways like T type, U type, Y type passages. But when there are some walkers and/or runners, respondents preferred to select the way where walkers or runners are. And more over the ratio of the ways that runners are on is comparatively higher than walkers. On 'ㅏ'type, 'ㅓ'type and 3 way type passages, even though the walkers and/or runners are affected to answerers, straight way were most preferred. And it is clear that peoples like bright passages. On the other hands, peoples responded as they like right, downward and near stairs more than left, upward and far stairs, respectively. and very few selected escalator and elevator for as evacuation stairs.

• Progress in Medical Physics
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• v.27 no.3
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• pp.139-145
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• 2016

With the development in field of industry and medicine, new machines and techniques are being launched. Moreover, the complexity of the techniques is associated to an increasing risk of incident. Especially, a small error in radiotherapy can lead to a serious patient-related incident, risk management is necessary in radiotherapy in order to reduce the risk of incident. However, in field of radiotherapy, there are no legally binding clauses for risk management and there is an absence of risk management systems at an institutional level. Therefore, we analyzed institutional status of risk management, reporting & classification systems, and risk assessment & analysis in 31 countries. For risk management and reporting systems, 65% of countries investigated had legislation or regulations; however, only 35% of countries used classification systems. It was found that 43% more countries had legislation for risk management in healthcare than those for radiotherapy; 19% more countries had reporting systems for healthcare than those for radiotherapy. For classification systems, 60% more countries had legislation, recommendation, and guidelines in the field of radiotherapy than those for healthcare. Recently, international institutes have published several reports for risk management and patient safety in radiotherapy, owing to which, countries adopting risk management for radiotherapy will gradually increase. Before adopting risk management in Korea, we should precisely understand the procedures and functions of risk management, in order to increase efficiency of risk management because classification & reporting system and risk assessment & analysis are connected organically, and institutional management is needed for high quality of risk management in Korea.