• Journal of Microbiology and Biotechnology
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• v.9 no.3
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• pp.346-351
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• 1999

Tumor cells may alter the expression of proteins involved in antigen processing and presentation, allowing them to avoid recognition and elimination by cytotoxic T cells. In order to investigate whether the major histocompatibility complex (MHC) class I-mediated antigen processing machinery is preserved in human lung cancer cell lines, we examined the expression of multiple components of the MHC class I antigen processing pathway, including transporter associated with antigen processing (TAP), $\beta_2$-microglobulin, MHC class I molecules, and chaperones which have not been previously examined in this context. Row cytometry analysis showed that the cell surface expression of MHC class I molecules was downregulated in all of the cell lines. While some cell lines showed no detectable expression of MHC class I molecules, pulse-chase experiments showed that MHC class I molecules were synthesized in the other cell lines but not transported from the endoplasmic reticulum to the cell surface. Low or nondetectable levels of TAP1 and/or TAP2 expression were demonstrated by Western blot analysis in all of the cell lines, representing a variety of lung tissue types. In some cases, this was accompanied by loss of tapasin expression. Our findings suggest that downregulation of antigen processing may be one of the strategies used by tumors to escape immune surveillance. This study provides further information for designing the potential therapeutic applications such as immunotherapy and gene therapy against cancers.

• Journal of Fisheries and Marine Sciences Education
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• v.24 no.6
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• pp.977-988
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• 2012

The purpose of this study was to help teachers increase the level of student's school life satisfaction by comparing between the practical data of a group which have an accordant perception for class teacher's discipline style perceived by between teacher him/herself and student with another group which have a discordant perception for class teacher's discipline style perceived by between teacher him/herself and student. For this study, 1460 second grade special high school students in Pusan were selected. And 1273 students and 56 teachers' questionnaires were used for analysis, while 5 questionnaires went uncompleted. T-test and Multiple Regression Analysis were used for compiling statistics of collected data. The results of this study are as follows: First, perceptions about the teacher's discipline style perceived by between teacher him/herself and student were different. Second, the levels of student's school life satisfactions were different by two group. A group which has an accordant perception for class teacher's discipline style perceived by teacher him/herself and student shows the high level of school life satisfaction than B group which has an discordant perception. Last, class teacher's discipline style which affects the level of student's school life satisfaction was different by the two group. These results suggest that to increase the level of student's school life satisfaction, class teachers have to a mutual understanding first, and then approach their students with different discipline style by the level of their interactive relationship with their students.

• Journal of the Korean School Mathematics Society
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• v.17 no.3
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• pp.385-408
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• 2014

The purpose of this study is to find out the actual status of the math after-school program in the elementary school and the content of the program. We survey the 115 math external math lecturers of the 100 elementary schools in Busan and analyze the results. Research questions are set as follows. 1. What is the status of the elementary math after-school? 2. How is the content of the program of the elementary math after-school? The results of the survey are analyzed as follows. First, any of the external math after-school lecturer did not major in math education and 87% of them majored in another discipline. Second, 47% of the external math after-school lecturers are employed by privately-held companies. Third, 64.4% of the content of the after-school programs is the supplement and deepening of the regular math class. Fourth, 76.5% of the time of the first class of the math after-school program is 50 minutes and 46% of the math after-school opens 5 classes per a week. Fifth, most programs consist of the problem-solving style class. Sixth, it is difficult to run the math after-school according to students' level and grade. Based on the above discussion, I suggest the following. First, math after-school class should be the action-oriented class to motivate the positive and interested participation of the students. Second, lecturer training and various math class programs is required to improve the quality of the math after-school class.

• The korean journal of orthodontics
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• v.45 no.3
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• pp.113-120
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• 2015

Objective: This study compared occlusal contact areas of ideally planned set-up and accomplished final models against the initial in class I and II molar relationships at finishing. Methods: Evaluations were performed for 41 post-orthodontic treatment cases, of which 22 were clinically diagnosed as class I and the remainder were diagnosed as full cusp class II. Class I cases had four first premolars extracted, while class II cases had maxillary first premolars extracted. Occlusal contact areas were measured using a three-dimensional scanner and RapidForm 2004. Independent t-tests were used to validate comparison values between class I and II finishings. Repeated measures analysis of variance was used to compare initial, set up, and final models. Results: Molars from cases in the class I finishing for the set-up model showed significantly greater contact areas than those from class II finishing (p < 0.05). The final model class I finishing showed significantly larger contact areas for the second molars (p < 0.05). The first molars of the class I finishing for the final model showed a tendency to have larger contact areas than those of class II finishing, although the difference was not statistically significant (p = 0.078). Conclusions: In set-up models, posterior occlusal contact was better in class I than in class II finishing. In final models, class I finishing tended to have larger occlusal contact areas than class II finishing.

• Perspectives in Nursing Science
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• v.11 no.2
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• pp.132-143
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• 2014

Purpose: This study was designed to explore adolescents' experience with yoga class in South Korea. Methods: Qualitative data were collected by focus group interviews from February to March 2014. Eleven adolescents who experienced yoga class were recruited from two different schools. The interview questions investigated adolescents' experience with yoga regarding expectations before yoga class, positive changes after yoga, and advice for future yoga classes. Results: Three primary themes from the qualitative content analysis include 1) motivation to join a yoga class, 2) perceived benefits after class and 3) suggestions for school-based yoga. We found that high school students had intrinsic and extrinsic motivations to join yoga classes, and the perceived benefits included physical, psychological, cognitive and social aspects. The students also indicated the need for support by person, yoga with fun and information, yoga tailored by individual goal, simple and easy class. Conclusion: These results suggest that yoga could be an appropriate intervention for holistic health care, and school-based yoga should be applied by focusing on the various situational needs of adolescents'. Furthermore, when yoga leads to healthy habits compared to just simple exercise, a balanced development of adolescents can be achieved.

• Journal of the Korean Society of Earth Science Education
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• v.3 no.1
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• pp.36-46
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• 2010

The purpose of this study is to find out the influence of MBL Exhibition Class on the Elementary School students' academic achievement, scientific research abilities and affective characters. For the purpose, three classes were sampled in the 5th grade of an elementary school. Among the three classes, two were designated as the comparative classes consisted of 68 students and the other was the experimental class, 33 students. The comparative classes were given lessens according to the content presented in the textbook of 7th Education Curriculum and the experimental class was given re-built lessons with using MBL machines. Before and after giving lessons, students of both classes took a test for science academic achievement. And also the scientific research abilities and affective characters were examined. The conclusions from this study is as follows. First, according to the result of science academic achievement test after giving lessons, the mean of the experimental class was higher than that of the comparative classes meaningfully. Second, scientific research abilities of the experimental class was shown higher than that of the comparative classes meaningfully. Specially, basic research abilities were improved very meaningfully and only hypothesis-building ability was improved among integrated research abilities. Third, it doesn't seem that MBL exhibition class is effective on affective characters(interest, attitudes).

• Journal of the Korean Society of Earth Science Education
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• v.12 no.3
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• pp.174-183
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• 2019

The purpose of this study was to investigate the effects of situation-based class using digital storytelling on elementary school students' science class motivation and scientific attitude for 50 fifth graders in B elementary school in P metropolitan city. In order to conduct this study, 25 students in 5th grade were selected as research group and 25 students in another class as comparative group, and the research group conducted situation-based classes using 8-hour digital storytelling. The comparative group received 8 classes of general science classes by curriculum. The results of this study are as follows. First, the situation-based class using digital-storytelling has a statistically significant effect on elementary school students' science learning motivation. Second, situation-based class using digital-storytelling has a statistically significant effect on the scientific attitudes of elementary school students. It is thought that the situation-based class through digital-storytelling has a positive effect on the exploration of science principles through students' daily experiences.

• Journal of Korean Elementary Science Education
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• v.38 no.3
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• pp.331-344
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• 2019

This study aims to analyse science-gifted elementary students' perception of speech in general school class, school science class, and science-gifted class and the relationship between their voluntary speech and scientific creativity. For this, 39 fifth-graders in the Science-Gifted Education Center at Seoul Metropolitan Office of Education in Korea were asked about their frequency of voluntary speech on each class situation, the reasons for such behavior, and their general opinions about speech. Also, researchers collected the teachers' observation on students' speech in class. To get the scores for students' scientific creativity, four different subjects of tasks were presented. The students' scientific creativity scores were used for correlation analysis with their frequency of speech. The main findings from this study are as follows: First, science-gifted elementary students tended to be passive in science-gifted class compared to general school and school science class. Second, the main reason for the low frequency of students' speech in school classes is that they do not have many opportunities to make presentations. Third, a survey of students' general thoughts on speech showed that more students wanted to make a speech voluntarily in class than the opposite. Fourth, the four different scientific creativity tasks had little correlation. Fifth, the correlations between the frequency of voluntary speech and the scores of scientific creativity were mostly low, with significant results only for plant task. Sixth, the correlations between the frequency of voluntary speech and the two components that make up scientific creativity, originality and usefulness, were also mostly low, but significant results for both were found in plant task, with originality having a higher correlation than usefulness. Based on this results, this study discussed the meanings and implications of students' voluntary speech on elementary science education and creativity education.

• Journal of the Korean School Mathematics Society
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• v.4 no.2
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• pp.103-113
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• 2001

The teaching-learning method utilizing Web makes it possible for the students take the initiative in any field and offers the teaching strategy, methodology and teaching-learning materials suitable for students' ability and standard. The purpose of this study is to investigate the characteristics of WBI in mathematics class for the effective teaching and learning focusing on the unit 'Function' in the 1st grade of middle school and verify its effectiveness by developing the WBI programs which can progress learning achievement and applying them to math class. Two hypotheses were established for this study. Hypothesis 1 : There will be meaningful difference between the group that studies under WBI and the one that doesn't, Hypothesis 2 : There will be meaningful difference in the attitude and interest toward learning between the group that studies under WBI and the one that doesn't. In order to find out the result, I have made a comparative analysis through t-verification on the object of two classes of the 1st grade in P middle school that I have been working for. The result shows that the class utilizing WBI is more effective than the traditional lecture-oriented class since there is a meaningful difference between the control group and experimental one and also that the class based on WEB has a great influence on students' interest and positive attitude toward math class.

• Journal of the Korean Society of Earth Science Education
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• v.4 no.3
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• pp.218-230
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• 2011

The aim of this current study is to survey and analyze the degree of concern and difficult of elementary school teachers in elementary school science classes, and providing the results to teachers as a basic reference to improve their scientific specialties. As a result, firstly, the degree of concern of elementary school teacher in science class is more than normal level. Secondly, the degree of concern in science class differs dependent on environmental factors. Next, the degree of difficulty about science class was under normal level. Among area surveyed, physical and psychological environment were lower compared with other areas, and the difficulty in evaluation of class result was comparably higher than others. At fourth, teacher's degree of difficulty in science class was dependent on environment factors, but not on gender. Finally, there was reverse correlation between degree of concern and the degree of difficulty of elementary school teachers in science class. Further, the degree of concern in student knowledge showed more significant reverse correlation with all of area tested.