• 제목/요약/키워드: Scan technique

검색결과 594건 처리시간 0.028초

Equilibrium Binding of Wild-type and Mutant Drosophila Heat Shock Factor DNA Binding Domain with HSE DNA Studied by Analytical Ultracentrifugation

  • Park, Jin-Ku;Kim, Soon-Jong
    • Bulletin of the Korean Chemical Society
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    • 제33권6호
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    • pp.1839-1844
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    • 2012
  • We have investigated binding between wild-type and mutant Heat Shock Factor (HSF) DNA binding domains (DBDs) with 17-bp HSE containing a central 5'-NGAAN-3' element by equilibrium analytical ultracentrifugation using multi-wavelength technique. Our results indicate that R102 plays critical role in HSE recognition and the interactions are characterized by substantial negative changes of enthalpy (${\Delta}H^0_{\theta}=-9.90{\pm}1.13kcal\;mol^{-1}$) and entropy (${\Delta}S^0_{\theta}=-12.46{\pm}3.77cal\;mol^{-1}K^{-1}$) with free energy change, ${\Delta}G^0_{\theta}$ of $-6.15{\pm}0.03kcal\;mol^{-1}$. N105 plays minor role in the HSE interactions with ${\Delta}H^0_{\theta}$ of $-2.54{\pm}1.65kcal\;mol^{-1}$, ${\Delta}S^0_{\theta}$ of $19.28{\pm}5.50cal\;mol^{-1}K^{-1}$ and ${\Delta}G^0_{\theta}$ of $-8.35{\pm}0.05kcal\;mol^{-1}$, which are similar to those observed for wild-type DBD:HSE interactions (${\Delta}H^0_{\theta}=-3.31{\pm}1.86kcal\;mol^{-1}$, ${\Delta}S^0_{\theta}=17.38{\pm}6.20cal\;mol^{-1}K^{-1}$ and ${\Delta}G^0_{\theta}=-8.55{\pm}0.06kcal\;mol^{-1}$) indicating higher entropy contribution for both wild-type and N105A DBD bindings to the HSE.

발치 후 지르코니아 보철물 제작에서 최적의 연조직 적합 형성을 위한 디지털 치료 증례 (Digital approach for fabrication of zirconia restoration with optimal gingival adaptation after tooth extraction: A case report)

  • 마이항나;이두형
    • 대한치과보철학회지
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    • 제58권3호
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    • pp.217-220
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    • 2020
  • 발치 후 고정성 지르코니아 보철물을 제작하는 경우 통상적으로 임시레진 보철물을 수작업으로 제작하고 보철단계에서 인상채득하여 최종 보철물을 제작한다. 이러한 전통적인 방식은 임시보철물과 최종 보철물 사이의 연계가 부족하고 결과의 심미적 기능적 예측성이 낮을 수 있다. 현재 CAD/CAM 방식의 보철물 제작과 관련 디지털 기술이 발전하여 진료에서 다양하게 활용되고 있다. 본 증례에서 발치 후 고정성 단일구조 지르코니아 보철물을 계획하는 경우 CAD/CAM 방식 임시보철물, 발치와 치유 후의 구내스캔, 컴퓨터 영상중첩술을 이용하여 최적의 가공치 적합도를 가지며 치료의 결과 예측도가 향상된 디지털 방식을 소개하고자 한다.

비침습성 플라시보 침 맹검의 시각적 요소 평가 (A Visual Factor of Blinding of the Non-Penetrating Placebo Needle)

  • 박재현;채윤병;박히준;이혜정
    • Korean Journal of Acupuncture
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    • 제25권4호
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    • pp.175-185
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    • 2008
  • Objective : Acupuncture (from the Latin acus, "needle," and pungere, "to prick") is a technique of inserting and manipulating fine needles at specific points on the body. As a placebo acupuncture needle device was developed based on the visual impact of needling, it has been raised that it is useful only when acupuncture points and needling are visible to subjects. To examine the visual factor of the placebo acupuncture, the present study was aimed to compare the blinding index of the verum and placebo acupuncture between masked and unmasked situation. Methods : Thirty-six patients were randomly alloted to be stimulated with a verum or placebo acupuncture in a cross-over design. They were asked to guess a right answer whether they were stimulated with the verum or placebo acupuncture at LI4 in an unmasked or masked situation. The penetrating, pain, and deqi sensations were also measured after the stimulation using modified visual analogue scale. Results : The correct answer rate of the placebo acupuncture was 22.2% and 16.7% in an unmasked and masked situation, respectively (P>0.767). The blinding index of the placebo acupuncture was -0.56 (95%CI -0.84 to -0.27) and -0.67 (95%CI -0.91 to -0.42) in an unmasked and masked situation, respectively. The penetrating and deqi sensation of the verum acupuncture were significantly higher than those of the placebo acupuncture in both unmasked and masked situation. The pain sensation of the verum acupuncture was significantly higher than that of the placebo acupuncture in masked situation, but not in unmasked situation. Conclusion : Blinding of the placebo acupuncture was successful both in the unmasked and masked situation. These finding indicate that visual factor might not play a critical role in blinding of the placebo needle. We suggest that placebo needle would be also useful in a functional magnetic resonance imaging scan even when the subject could not see the placebo needle.

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On-orbit test simulation for field angle dependent response measurement of the Amon-Ra energy channel instrument

  • 성세현;김석환;류동옥;홍진석
    • 천문학회보
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    • 제37권2호
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    • pp.211.1-211.1
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    • 2012
  • The on-orbit test simulation for predicting the instrument directional responsivity was conducted by the Monte Carlo based integrated ray tracing (IRT) computation technique and analytic flux-to-signal conversion algorithms. For the on-orbit test simulation, the Sun model consists of the Lambertian scattering sphere and emitting spheroid rays, the Amon-Ra instrument is a two-channel including a broadband scanning radiometer (energy channel) and an imager with ${\pm}2^{\circ}$ FOV (visible channel). The solar radiation produced by the Sun model is directed to the instrument viewing port and traced through the dual channel optical train. The instrument model is rotated on its rotation axis and this gives a slow scan of the Sun model over the full field of view. The direction of the incident lights are fed with scanned images obtained from the visible channel instrument. The instrument responsivity was computed by the ratio of the incident radiation input to the instrument output. In the radiometric simulation, especially, measured BRDF of the 3D CPC was used for scattering effects on radiometry. With diamond turned 3D CPC inner surface, the anisotropic surface scattering model from the measured data was applied to ray tracing computation. The technical details of the on-orbit test simulation are presented together with field-of-view calibration plan.

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EMD를 이용한 초음파 비파괴 평가용 3차원 영상처리 소프트웨어 개발 (Development of 3D Image Processing Software using EMD for Ultrasonic NDE)

  • 남명우;이영석;양옥렬
    • 한국산학기술학회논문지
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    • 제9권6호
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    • pp.1569-1573
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    • 2008
  • 본 논문은 핵발전소 증기발생기의 초음파 비파괴 검사용 프로그램 개발에 관한 것이다. 개발된 프로그램은 A, B, C, D-스캔과 같은 고전적인 해석방법뿐만 아니라 3차원 영상처리 기법을 이용하여 증기발생기 내부에 발생한 결함을 해석하고 검출할 수 있다. 결함의 3차원 영상은 핵발전소의 파이프라인으로부터 얻어진 1차원 초음파 데이터를 EMD(Empirical Mode Decomposition)로 분석해 결함의 위치를 구하고 voxel을 이용하여 구현하였다. 얻어진 3차원 영상은 2차원 해석방법을 사용하지 않더라도 결함의 위치, 형태, 크기 등과 같은 유용한 정보를 얻는데 용이하다. 개발된 프로그램은 이미 결함의 위치 및 모양, 크기 등을 알고 있는 시편의 측정에 사용하여 프로그램의 정확성을 검증하였고, 3차원 영상으로 결함의 입체적 모양을 구현하였다.

순서회로를 위한 경계면 스캔 구조에서의 지연시험 연구 (A Study of Delay Test for Sequential circuit based on Boundary Scan Architecure)

  • 이창희;김정환;윤태진;남인길;안광선
    • 한국정보처리학회논문지
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    • 제5권3호
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    • pp.862-872
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    • 1998
  • 본 논문에서는 경계면 스캔 구조에서의 클럭 입력을 갖는 순서회로를 위한 지연시험 구조와 지연시험 절차를 개발하였다. 지연시험 대상회로가 클럭 입력을 갖는 순서회로일 경우, 기존의 경계면 스캔 구조에서의 지연시험은 중복패턴의 입력, 클럭 입력과 데이터 입력과의 시간 간격과, 패턴 입력과 응답값 캡쳐까지의 시간 문제에 의해 적절치 않음을 보였다. 본 논문에서 제안하는 ARCH-S는 클럭 카운팅 기술을 이용하여 정해진 수의 클럭을 대상회로의 클럭 입력선에 적용시킴으로써 대상회로에 입력되는 입력 패턴의 중복을 피할 수 있다. 또한 대상회로를 정상 속도에서 동작할 수 있도록 시스템 클럭을 TCK로 사용한다. 연속적인 클럭 발생에 TCK를 사용함으로써 대상회로를 정상 속도에서 검증할 수 있다. 제안된 ARCH-S 구조는 시뮬레이션을 통해 동작의 정확성과, 기존의 구조와 비교하여 향상된 성능을 가짐을 확인하였다.

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모핑 기법을 활용한 40대 남성 하반신 가상모델 생성에 관한 연구 (A Study of 3D Virtual Fitting Model of Men's Lower Bodies in Forties by Morphing Technique.)

  • 박선미;남윤자;최경미
    • 한국의류학회지
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    • 제31권3호
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    • pp.463-474
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    • 2007
  • With rapid expansion in e-retailing of apparel business, personalized fitting model service shows the possibility as the differentiated marketing strategy in cyber shopping. According as necessity of personalized fitting model construction rises, it is tried personalized fitting model creation in several fields such as computer engineering, mechanical engineering, information engineering. But, because existent study was concentrated only on human body modeling, it does not reflect average morphological characteristics of human body properly. In this study, we wish to examine if morphing is fit for expressing characteristic of average human body shape and suggest desirable morphing. We used 3-D scan data of 254 Korean middle aged men collected by Size Korea 2004. The result of this study are as follows: Lower body types were categorized by height hip girth and lower drop(hip girth-navel girth) which were main factors of lower body shape. Then each factor was divided into 3 groups respectively, 30% in the middle, over 30%, under 30%. In 27 groups, the group which belonged to 30% in the middle of height, 30% in the middle of hip girth, 30% in the middle of lower drop was selected as a representative group. We tested geometrical figure by differ volume, tilt, position of point. And we created a representative type of men's lower bodies by morphing the representative group and analyzed it's horizontal, vertical sections. A representative type which was created by morphing reflected a real body and changed realistically at the part of hip, crotch, calf muscle and so on. A cross sections of a representative type were similar to average cross sections of the representative group in size and shape. So it was proved that morphing was successful.

CNT를 이용한 Supercapacitor의 충.방전 특성 (The Effect of CNT Electrode on the Charging and Discharging Characteristics of Supercapacitor)

  • 허근;명성재;이용현;전명표;조정호;김병익;심광보
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2007년도 추계학술대회 논문집
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    • pp.275-275
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    • 2007
  • Two sorts of electrode composed of Sulpur/CNT/PVDF and Silver/CNT/PVDF were prepared by in situ chemical method and their electrochemical performance were evaluated by using cyclic voltammetry, impedance measurement and constant-current charge/discharge cycling technique. Also, composite electrodes were characterized by FE-SEM and BET. Raw materials such as CNT/Silver and CNT/Sulfur were mixed in ethanol, dried. These mixed materials were heated at 900 and $320^{\circ}C$ for 2hr, respectively in order to enhance contact among CNT electrodes. Electric double layer capacitor cells were fabricated using these mixed powder with polymer of PVDF. For the charging and discharging characteristics measured at scan rate of 1 mA/s, Supercapacitor of Sulphur-CNT-PVDF electrode showed a better performance than that of Ag-CNT-PVDF, which seems to be related with lower contact resistance of Sulphur-CNT-PVDF electrode.

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Accuracy of intraoral scans of edentulous jaws with different generations of intraoral scanners compared to laboratory scans

  • Kontis, Panagiotis;Guth, Jan-Frederik;Schubert, Oliver;Keul, Christine
    • The Journal of Advanced Prosthodontics
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    • 제13권5호
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    • pp.316-326
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    • 2021
  • PURPOSE. Purpose of this in vitro study was to determine the accuracy of different intraoral scans versus laboratory scans of impressions and casts for the digitization of an edentulous maxilla. MATERIALS AND METHODS. A PEEK model of an edentulous maxilla, featuring four hemispheres on the alveolar ridges in region 13, 17, 23 and 27, was industrially digitized to obtain a reference dataset (REF). Intraoral scans using Cerec Primescan AC (PRI) and Cerec AC Omnicam (OMN), as well as conventional impressions (scannable polyvinyl siloxane) were carried out (n = 25). Conventional impressions (E5I) and referring plaster casts were scanned with the inEOS X5 (E5M). All datasets were exported in STL and analyzed (Geomagic Qualify). Linear and angular differences were evaluated by virtually constructed measurement points in the centers of the hemispheres (P13, P17, P23, P27) and lines between the points (P17-P13, P17-P23, P17-P27). Kolmogorov-Smirnov test and Shapiro-Wilk test were performed to test for normal distribution, Kruskal-Wallis-H test, and Mann-Whitney-U test to detect significant differences in trueness, followed by 2-sample Kolmogorov-Smirnov test to detect significant differences in precision (P < .008). RESULTS. Group PRI showed the highest trueness in linear and angular parameters (P < .001), while group E5I showed the highest precision (P < .001). CONCLUSION. Intraoral scan data obtained using Primescan showed the highest trueness while the indirect digitization of impressions showed the highest precision. To enhance the workflow, indirect digitization of the impression itself appears to be a reasonable technique, as it combines fast access to the digital workflow with the possibility of functional impression of mucosal areas.

터널 라이닝 공동에 대한 GPR 신호 특성 분석을 위한 수치해석 연구 (A Study on Numerical Analysis for GPR Signal Characterization of Tunnel Lining Cavities)

  • 고규현;이성진
    • 한국지반공학회논문집
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    • 제37권10호
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    • pp.65-76
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    • 2021
  • 노후화된 터널 구조물의 라이닝 내부 및 배면에 존재하는 공동은 다양한 원인에 의해 발생되며 대부분의 경우 육안검사가 불가능한 곳에 존재하기 때문에 이에 대한 점검이 쉽지 않다. 최근에는 지반탐사레이더와 같은 비파괴시험 등을 이용하여 터널 라이닝과 배면에 대한 상태를 평가하는 시도가 이루어지고 있으며, 이와 관련된 다양한 모형시험 및 해석연구가 수행되고 있다. 본 연구에서는 gprMax 소프트웨어를 이용하여 터널 라이닝 모형 시험체 조건에 대한 GPR 신호특성을 시각화하여 분석하였고, 이를 모형체 시험 결과와 비교하였다. 모형체 시험에 적용된 GPR 해석모델은 터널 라이닝 및 내부 공동 등 매질 변화에 대한 전자기파 신호변화를 합리적으로 모사하였다. 검증된 수치해석모델을 이용하여 터널 라이닝의 두께, 내부의 공동 존재와 규모, 방수막의 영향, 주파수대역의 영향 등을 평가하기 위한 GPR 분석 기법 개발에 필요한 데이터를 확보하였다.