• 대한두경부종양학회지
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• 제16권2호
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• pp.206-211
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• 2000

Objectives: Any uptake of I-131 after total thyroidectomy means the remant thyroid tissue or distant metastasis of the thyroid cancer. However diffuse hepatic uptake of I-131 without abnormal uptake was showen in many cases on I-131 whole body scan. The aim of this study was to classify the liver uptake after I-131 scan and to evaluate the analysis of this finding. Materials and Methods: Between 1982 and 1998, 104 patients(l4 males, 90 females) with normal liver function underwent I-131 scan after total thyroidectomy. Prospectively we reviewed the films of the whole body scan and analysed the correlations between results of radioiodine uptake, pathologic diagnosis, prognostic factors, lymphatic metastasis, and thyroid function test. Result: Diffuse hepatic uptake was found in 44 of 104(42%) patients. 10 of 39(26%) patients on I-131 100mCi, and 34 of 63(54%) on I-131 150mCi showed hepatic uptake. 52 of 104(50%) patients was locally invasive thyroid cancer. The rate of the hepatic uptake was no significant differences with the thyroid hormone levels(T3, Free T4) and thyroglobulin between uptake group and non-uptake group. Conclusion: The rate of I-131 uptake was high in high-dose radioiodine treatment group. However, we can not find any correlation among the thyroid functions, the extent of metastasis or the extent of local invasion. We need further study to find out the causes of the hepatic uptake of I-131 after total thyroidectomy, besides liver metabolism of I-131 attached thyroid hormones.

• Journal of Mechanical Science and Technology
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• 제17권3호
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• pp.343-349
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• 2003

The fuselage-wing intersection suffers from the cyclic bending moment of variable amplitude. Therefore, the influence of cyclic bending moment on the delamination and the fatigue crack propagation behavior in AFRP/Al laminate of fuselage-wing was investigated in this study. The cyclic bending moment fatigue test in AFRP/Al laminate was performed with five levels of bending moment. The shape and size of the delamination Lone formed along the fatigue crack between aluminum sheet and aramid fiber-adhesive layer were measured by an ultrasonic C-scan. The relationships between da/dN and ΔK, between the cyclic bending moment and the delamination zone size, and between the fiber bridging behavior and the delamination zone were studied. As results, fiber failures were not observed in the delamination zone in this study, the fiber bridging modification factor increases and the fatigue crack growth rate decrease and the shape of delamination zone is semi-elliptic with the contour decreasing non-linearly toward the crack tip.

• 전자공학회논문지B
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• 제32B권10호
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• pp.1280-1285
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• 1995

In this paper the optimized overlap driving scheme for improving the reduction problem of the operating voltage range occured by the overlap driving scheme proposed precedently and increasing the contrast ratio of screen image in the simple matrix LCDs is proposed. The characteristic estimation of the proposed method was performed in a condition that the number of scan electrodes was 120 and the threshold voltage of LC pixel was 2V and the overlap rate of scan signal was varied from 0% to 40% . As a result of estimation compared with the overlap driving scheme proposed precedently, this new method was certified as a method which it could increase the operating voltage range of the LC pixel by 16% in 20% overlap condition and it's operating voltage range was also increased very much with the increase of the overlap rate. Consequently this newly proposed method was certified as a method which it could maintain the improvement effect of the operating characteristics obtained by the overlap driving scheme proposed precedently with the big improvement in the contrast ratio of screen image.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1966년도 제5회 학술대회
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• pp.93.3-94
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• 1966

The fact that colloidal particulates of rdaiogold are mainly and effectively eliminated from the blood stream by phagocytic activity of Kupffer's cells of the liver has been successfully adopted to the diagnosis if certain liver diseases and the same principle has opened a new avenue to the study of the organ by obtaining scan. Indeed, the latter procedure has been widely used for the detection of space-occupying lesions of cirrhosis of the liver. Nevertheless problem of differential diagnosis of monochromatic "cold" areas or "mottling" of the internal structure on the scan limited the value of this diagnostic modality. The present investigation is aimed at improving intepretation of photoscan findings with the aid of blood clearance rate of the intravenously injected colloidal $^{198}Au$.

• Progress in Superconductivity
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• 제3권1호
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• pp.125-129
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• 2001

NiO buffer layers were deposited on texture Ni tapes fur YBCO coated conductors by MOCVD(metal organic chemical vapor deposition) method, using a single solution source. Variables were deposition temperature and flow rate of $0_2$carrier gas. At higher temperatures, The NiO(111) texture was well developed, but the NiO(200) texture was developed at low temperatures. The best result was obtained at the deposition temperature of$ 470^{\circ}C$ and the gas flow rate of 200 sccm. FWHM value of $\omega$-scan fur NiO(200) of the film and $\Phi$-scan for NiO(111) of the film was $4.2^{\circ}$ and $7^{\circ}$, respectively.

• 한국전기전자재료학회논문지
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• 제15권12호
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• pp.1065-1069
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• 2002

The addressing time should be reduced by modifying cell structure and/or driving method in order to replace the dual scan system by single scan and increase the luminance in large ac plasma display panel(PDP). In this paper, the effects of the addressing time was decreased with decreasing thickness of dielectric layer on the front glass and thickness of white dielectric layer on the rear glass. the decreasing rate were 160ns/10$\mu\textrm{m}$ and 270ns/10$\mu\textrm{m}$, respectively Also in case of decreasing the height of barrier rib, addressing time was decreased at the rate of Sons/10$\mu\textrm{m}$.

• E2M - 전기 전자와 첨단 소재
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• 제10권7호
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• pp.668-673
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• 1997

A Single-crystalline Mn-Zn Ferrite (110 orientation) was masklessly etched by focused Ar laser irradiation in an H$_3$PO$_4$ solution. The depth of the etched grooves increases with increasing a laser power, decreasing a scan speed, and increasing the H$_3$PO$_4$concentration. The width of the etched grooves increases with a increasing laser power, but was relatively insensitive to the scan speed and H$_3$PO$_4$concentration. High etching rate of up to 714 ${\mu}{\textrm}{m}$/s and an aspect ratio of 6 for vertical slab structure have been obtained by the light-guiding effect of the laser bean in the H$_3$PO$_4$ solution.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1707-1710
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• 2014

Background: The objective of this study was to evaluate baseline use and positive rates of staging images (bone scan, CT) in newly diagnosed patients with prostate cancer (PCa) and to improve staging image overuse. Materials and Methods: This retrospective study covered a consecutive series of patients with PCa who underwent stage imaging at our institution between 2006 and 2011. Various clinical and pathological variables (age, PSA, biopsy Gleason score, clinical T stage, positive biopsy core rate) were evaluated by multivariate logistic regression analysis for their ability to predict a positive staging image. All patients were stratified according to the NCCN risk stratification and positive rates were compared in each risk group. Results: 410 patients (100%) underwent a bone scan and 315 patients (76.8%) underwent a CT scan. Some 51 patients (12.4%) had a positive bone scan, clinical T3 and T4 being significant independent predictors. Positive bone scan rates for low-, intermediate-, high-, and very high-risk groups were 0%, 0%, 8.25%, and 56.6%. Some 59 (18.7%) patients had a positive CT scan, with elevated PSA and clinical T3, T4 as significant independent predictors. Low-, intermediate-, high- and very high-risk group rates were 0%, 0%, 13.8% and 80.0%. Conclusions: The incidences of positive staging image in low- and intermediate- risk group were reasonably low. Following feedback on these results, staging in low- and intermediate- risk groups could be omitted.

• Genomics & Informatics
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• 제17권3호
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• pp.26.1-26.12
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• 2019

Identification of fusion gene is of prominent importance in cancer research field because of their potential as carcinogenic drivers. RNA sequencing (RNA-Seq) data have been the most useful source for identification of fusion transcripts. Although a number of algorithms have been developed thus far, most programs produce too many false-positives, thus making experimental confirmation almost impossible. We still lack a reliable program that achieves high precision with reasonable recall rate. Here, we present FusionScan, a highly optimized tool for predicting fusion transcripts from RNA-Seq data. We specifically search for split reads composed of intact exons at the fusion boundaries. Using 269 known fusion cases as the reference, we have implemented various mapping and filtering strategies to remove false-positives without discarding genuine fusions. In the performance test using three cell line datasets with validated fusion cases (NCI-H660, K562, and MCF-7), FusionScan outperformed other existing programs by a considerable margin, achieving the precision and recall rates of 60% and 79%, respectively. Simulation test also demonstrated that FusionScan recovered most of true positives without producing an overwhelming number of false-positives regardless of sequencing depth and read length. The computation time was comparable to other leading tools. We also provide several curative means to help users investigate the details of fusion candidates easily. We believe that FusionScan would be a reliable, efficient and convenient program for detecting fusion transcripts that meet the requirements in the clinical and experimental community. FusionScan is freely available at http://fusionscan.ewha.ac.kr/.

• 핵의학기술
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• 제15권2호
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• pp.99-103
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• 2011

Brain Perfusion SPECT (Diamox)는 아세타졸아미드를 사용하여 혈관예비능을 평가하는데 아주 유용한 검사이다. 1day-protocol method는 영상의 질이 뛰어나고 한 번에 두 가지 영상을 얻을 수 있는 이점이 있어, 검사실과 내원 환자에 모두 유리하다. 하지만 긴 검사시간으로 인해 다른 검사보다 재검사율이 높은 문제점을 가지고 있다. 이에 시행한 환자의 성별, 나이, 상병, 머리고정기구 사용 여부에 따른 재검사율을 파악하여 검사의 최적화를 도모하고자 하였다. 2010년 3월부터 2011년 2월까지 시행한 환자 676명(남:359명, 여:317명)을 대상으로 하였으며, 머리의 움직임을 유발하는 요인을 성별, 연령, 상병의 종류, 머리고정기구 적용여부로 나누어 검사결과에 기여하는 여부와 정도를, 카이제곱 검정기법과 이분형 로지스틱 회귀분석기법을 사용하여 검증하였다. 남성이 3.4%, 여성이 1.5%로 남성이 여성보다 실패율이 높았으며, 70대가 1.0%로 가장 높은 실패율을 보였다. 카이제곱 검정결과 p-value는 0.001미만으로 통계적으로 유의한 차이가 있는 것으로 나타났다. 이분형 로지스틱 회귀분석결과에서는 성별, 상병(CI), 머리고정기구 사용이 통계적으로 유의한 수준에서 영향을 끼치는 요인으로 평가 되었다. 각각의 Wald value는 3.3, 3.7, 9.3으로 머리고정기구의 사용이 가장 큰 영향을 주는 것으로 나타났다. 연구결과를 통해 연령을 제외한 성별과 상병 그리고 머리고정기구 사용이 검사수행결과에 통계적으로 유의한 수준의 영향력을 가지는 요인들임을 알게 되었으며. 그 중 머리고정기구 사용은 검사수행결과에 끼치는 영향이 가장 큰 요인임을 알 수 있었다. 검사의 시행에 있어서 머리고정기구를 필수적으로 사용한다면 Brain Perfusion SPECT(Diamox)검사의 재검사율을 크게 낮출 수 있을 것으로 기대된다.