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Comparison of Fragility Using Natural Frequency and Damping Parameter in System (고유주파수와 감쇠비에 대한 시스템 손상도 비교)

  • Lee, Seok-Min;Jung, Beom-Seok
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.22 no.1
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    • pp.48-55
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    • 2018
  • The purpose of the present study is to compare the reduction rate of natural frequency and the increase rate of damping parameter with structural damage in system. For this purpose, experiment and numerical simulation analysis are performed for the 2-span H-Beam with lower natural frequency and higher damping parameter from free vibration in structure. The response signal by impact load before and after damage is analyzed at 14 locations. The response signals for all locations are performed fast fourier transform to estimate the natural frequency reduction rate and wavelet transform to estimate the damping parameter increase rate. The time domain function corresponding to each scale(frequency) is separated from the response signal by wavelet parameter. The estimation of damping parameter increase rate using wavelet transform is more sensitive than the estimation of natural frequency reduction rate in structure.

Suspension Culture-Mediated Tetraploid Formation in Mouse Embryonic Stem Cells

  • Lee, Jae-Hee;Gong, Seung-Pyo;Lim, Jeong-Mook;Lee, Seung-Tae
    • Reproductive and Developmental Biology
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    • v.36 no.1
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    • pp.21-26
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    • 2012
  • Suspension culture is a useful tool for culturing embryonic stem (ES) cells in large-scale, but the stability of pluripotency and karyotype has to be maintained $in$ $vitro$ for clinical application. Therefore, we investigated whether the chromosomal abnormality of ES cells was induced in suspension culture or not. The ES cells were cultured in suspension as a form of aggregate with or without mouse embryonic fibroblasts (MEFs), and 0 or 1,000 U/ml leukemia inhibitory factor (LIF) was treated to suspended ES cells. After culturing ES cells in suspension, their karyotype, DNA content, and properties of pluripotency and differentiation were evaluated. As a result, the formation of tetraploid ES cell population was significantly increased in suspension culture in which ES cells were co-cultured with both MEFs and LIF. Tetraploid ES cell population was also generated when ES cells were cultured alone in suspension regardless of the existence of LIF. On the other hand, the formation of tetraploid ES cell population was not detected in LIF-free condition, in which MEFs were included. The origin of tetraploid ES cell population was turned out to be E14 ES cells and not MEFs by microsatellite analysis and the basic properties of them were still maintained despite ploidy-conversion to tetraploidy. Furthermore, we identified the ploidy shift from tetraploidy to near-triploidy as tetraploid ES cells were differentiated spontaneously. From these results, we demonstrated that suspension culture system could induce ploidy-conversion generating tetraploid ES cell population. Moreover, optimization of suspension culture system may make possible mass-production of ES cells.

Prevalence of rotator cuff diseases in adults older than 40 years in or near Chuncheon city, Korea

  • Kim, Do-Young;Hwang, Jung-Taek;Lee, Sang-Soo;Lee, Jun-Hyuck;Cho, Min-Soo
    • Clinics in Shoulder and Elbow
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    • v.23 no.3
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    • pp.125-130
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    • 2020
  • Background: To determine the prevalence of rotator cuff diseases in a population older than 40 years in or nearby Chuncheon city, Republic of Korea. Methods: Sixty shoulders of 30 people older than 40 years who participated in a health lecture were examined for free by an orthopedic surgeon. Visual analog scale of pain and American Shoulder and Elbow Surgeons scores were assigned, and routine physical examination was performed. Ultrasonography was performed on the shoulder. Results: On ultrasonographic examination, there were one shoulder with full thickness rotator cuff tear, 20 of 60 (33%) with partial thickness rotator cuff tear, five of 60 (8%) with calcific tendinitis, one of 60 (2%) with tear of the long head of the biceps, and five of 60 (8%) with tendinitis of the long head of the biceps. Participants older than 60 years showed significantly high proportions of lesion of the long head of the biceps and rotator cuff diseases (P=0.019 and P=0.015, respectively). Participants who performed physical labor had high proportions of rotator cuff tear and rotator cuff disease (P=0.001 and P<0.001, respectively). Conclusions: Rotator cuff diseases showed a high prevalence in aged persons and resulted in a decrease in shoulder function.

Computation of Bessel Coordinates of the Cadastral Control Points by Trilateration Adjustment of GPS Baseline Measurements (GPS 관측기선의 삼변망 조정계산에 의한 우리나라 지적측량기준점의 베셀성과 산출)

  • Yang, Chul-Soo;Kang, Sang-Gu;Jung, Rea-Jung;Kim, Yong-Ho;Lee, Min-Seok
    • Journal of Korean Society for Geospatial Information Science
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    • v.15 no.3
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    • pp.41-49
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    • 2007
  • In this study, the software to compute Bessel coordinates by trilateration adjustment was developed, and the software was used to determine coordinates of the cadastral control points over the southern Korean peninsula. The baseline measured by GPS was reduced to the distance on geoid surface by applying PNU95 geoid model, and the distance on geoid surface was reduced to the plane grid distance by applying scale factor of map projection of Bessel coordinates. Using the plane grid distance, Bessel coordinates of 32 CORS (Continuously Operating Reference Station) were computed by free adjustment at first, and then the coordinates of the cadastral control points were computed by joining the control points to adjacent CORS. The result shows a possibility of construction of highly accurate and consistent cadastral survey network with coordinate error less than 1ppm of distance, when newly computing the coordinates of the control points by using distances measured by GPS.

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The Analysis of Communication Invigorating Element in the Play Spaces of Apartments - Focused on the Cases in Suncheon City - (아파트 놀이공간의 커뮤니케이션 활성화 요소 분석 - 전라남도 순천시 사례를 중심으로 -)

  • Yun, Yeo-Ran;Moon, Jeong-Min
    • Journal of the Korean housing association
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    • v.26 no.3
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    • pp.25-32
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    • 2015
  • Apartment complex has become the major residental type of the urban structure. apartment complex has started to equip various subsidiary welfare facilities recently. environmental planning for play space has especially been important due to the growing attention over children's emotional development. In this study, arrangement types for play spaces in apartments to invigorate communication had been analyzed focusing on physical environment. based on previous studies, the arrangement of subsidiary welfare facilities can be categorized into dispersal type, concentrative type, affiliated type, and affiliated concentration type, and the elements to invigorate communication consist of circulative elements which contain location of play space and affiliated facility, visual elements which contain visual openness, and social elements which draw arrangement types of benches. the result of the analysis devide the arrangement type into concentrative type, affiliated type, and affiliated concentration type. referring to the location of play space, the first, if it is situated outside of apartment complex, theme-centered play space can be equipped to invigorate communication, the second, if it is situated in the center of the complex or outside of the apartment complex, low fence can be applied for free sight, and the last, straight type of bench arrangement should be used in big scale play space, aspectant type and gazebo type of the arrangement can be situated only outside of complex. This research could serve as a baseline of physical environment analysis to invigorate communication for play space in apartment complex.

Influence of Climate Change on the Lifecycle of Construction Projects at Gaza Strip

  • El-Sawalhi, Nabil;Mahdi, Mahdi
    • Journal of Construction Engineering and Project Management
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    • v.5 no.2
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    • pp.1-10
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    • 2015
  • There is a high confidence based on scientific evidence that climate is changing over time. Now climate change is considered as one of the challenges facing the construction industry. As no project is risk free and climate change has a strong impact on the different phases of the construction project lifecycle. This research aimed at providing a platform of knowledge for the construction management practitioners about the impacts of climate change on the construction projects lifecycle, identify the most dangerous climate change factors on the construction project lifecycle, and identify the most affected phase by climate change factors through the construction projects lifecycle. The study depended on the opinions of civil engineers who have worked in the construction projects field among the reality of Gaza Strip. Questionnaire tool was adopted as the main research methodology in order to achieve the desired objectives. The questionnaire included 127 factors in order to obtain responses from 88 construction practitioners out of 98 representing 89.79% response rate about the influence of climate change on the generic lifecycle of construction projects. The results deduced that the most significant influence on the construction project lifecycle was related to the extreme weather events, rainfall change, and temperature change respectively. There was a general agreement between the respondents that the most affected phase by temperature, rainfall, and extreme weather events is the execution phase. The results also asserted with a high responses scale on the need to alternative procedures and clear strategies in order to face the climate change within construction industry.

Comparative study of prediction methods of power increase and propulsive performances in regular head short waves of KVLCC2 using CFD

  • Lee, Cheol-Min;Seo, Jin-Hyeok;Yu, Jin-Won;Choi, Jung-Eun;Lee, Inwon
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.11 no.2
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    • pp.883-898
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    • 2019
  • This paper employs computational tools to predict power increase (or speed loss) and propulsion performances in waves of KVLCC2. Two-phase unsteady Reynolds averaged Navier-Stokes equations have been solved using finite volume method; and a realizable k-ε model has been applied for the turbulent closure. The free-surface is obtained by solving a VOF equation. Sliding mesh method is applied to simulate the flow around an operating propeller. Towing and self-propulsion computations in calm water are carried out to obtain the towing force, propeller rotating speed, thrust and torque at the self-propulsion point. Towing computations in waves are performed to obtain the added resistance. The regular short head waves of λ/LPP = 0.6 with 4 wave steepness of H/λ = 0.007, 0.017, 0.023 and 0.033 are taken into account. Four methods to predict speed-power relationship in waves are discussed; Taylor expansion, direct powering, load variation, resistance and thrust identity methods. In the load variation method, the revised ITTC-78 method based on the 'thrust identity' is utilized to predict propulsive performances in full scale. The propulsion performances in waves including propeller rotating speed, thrust, torque, thrust deduction and wake fraction, propeller advance coefficient, hull, propeller open water, relative rotative and propulsive efficiencies, and delivered power are investigated.

A Usability Testing of the Word-Prediction Function of the AAC Keyboard for the People with Cerebral Palsy (보완대체의사소통(AAC) 글자판의 단어예측기능에 대한 뇌병변장애인 대상의 사용성 평가)

  • Lee, H.Y.;Hong, K-H.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.9 no.3
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    • pp.209-214
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    • 2015
  • The purpose of this study was to examine (1) the influence of the word-prediction function on the sentence generation speed and (2) the necessity, convenience, and satisfaction of the word-prediction function of the AAC keyboard. A total of 10 adults with cerebral palsy participated and the word-prediction function of the Korean high-tech AAC device called "MyTalkie Smart" keyboard was used for this study. Participants were required to generate sentence as voice outputs using a word-prediction function and letters direct-input function respectively, then they were required to evaluate the necessity, convenience, and satisfaction using a five-point Likert scale. Other user requirements were examined using a free feedback. The results of this study presented that the sentence generation speeds were faster when participants used a word-prediction function than using a letters direct-input function. However, there was no statistically significant difference between these two input methods, and it might be due to the lack of time to practice the new device. Participants showed positive responses for the necessity, convenience, and satisfaction of the word-prediction function.

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Therapeutic efficacy of the photoactivated sickle cells as novel drug delivery vehicle (약물전달 시스템 개발을 위한 여기된 광감응제의 응용)

  • Choe, Se-woon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.10a
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    • pp.958-960
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    • 2015
  • Sickle cells possess a unique combination of traits that may enable their use as models for novel synthetic tumor targeting controlled release drug carriers with the ability to treat disseminated tumors in advanced metastatic disease. In this study, we assess the ability of light-activated release sickle cells to enhance tumor delivery of the fluorescent dye calcein by delayed photolysis controlled release compared to free systemic administration of calcein. Sickle cells from mouse models of the disease were shown to preferentially accumulate in tumors compared to adjacent tissue, in 4T1 tumors in mice on a time scale about 12 hours. Sickle cells photosensitized with protoporphyrin IX achieved delayed release of 50% of contents 8-16 hours after photoactivation, which was deemed useful for in vivo delivery of cargo to tumors given the tumor accumulation time of the sickle cells. Sickle cells may be useful as a model for new synthetic drug carrier particles with delayed photolysis controlled release properties.

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Effects of Hull Form Variations on Resistance and Seakeeping Performance of Planing Hulls with and without Incoming Regular Waves (고속 활주선의 선형에 따른 저항 성능 및 규칙파 중 운동 성능 고찰)

  • Kim, Dong Jin;Kim, Sun Young;Kim, Seong Hwan;Seo, Jeong Hwa;Rhee, Shin Hyung
    • Journal of the Society of Naval Architects of Korea
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    • v.51 no.5
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    • pp.369-379
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    • 2014
  • Planing hull forms have significant influences on those hydrodynamic performances in calm water and in waves. Therefore, the hydrodynamic performance of a planing vessel should be predicted by model tests or theoretical calculations, and be confirmed whether it shows the performance requirements at the design stage. In this study, four planing hull forms are designed with the goal of the improvement of resistance and seakeeping performance, and 1/6.5 scale model tests are carried out in Seoul National University towing tank. The effects of design parameters such as length-to-beam ratio, deadrise angle and forebody shape on the hydrodynamic performance are investigated, based on model test results. Running attitude and resistance of model ships in calm water are also estimated by empirical formulae proposed by Savitsky (1964; 2007; 2012), and compared with the model test results. It is shown that calm water performance of non-prismatic planing hulls can be predicted well by Savitsky (2012)'s formula which improves the original Savitsky(1964/2007)'s formula by taking into account the variations of deadrise angles, and the actual angles between the hull bottom and the free surface.