• Journal of Sasang Constitutional Medicine
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• v.21 no.3
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• pp.122-130
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• 2009

1. Objectives: The objective of this study is to investigate the relationship between adiponectin and metabolic syndrome according to Sasang Constitution. 2. Methods: Six hundred sixty six participants were included in this cohort study. Sex, age, BMI(Body Mass Index), smoking, drinking, adiponectin level and Metabolic syndrome components were considerd. Sasang constitutional diagnosis was carried out by a sasang constitutional specialist using photos, questionnaires and PSSC(Phonetic System for Sasang Classification). 3. Results: In binary logistic analysis after adjustment of age, sex, BMI, smoking, drinking, adiponectin level and sasang constitution were related with Metabolic syndrome. 4. Conclusions: We suggest that adiponectin and sasang constitution are the important biomarker in Metabolic syndorme.

• Journal of Sasang Constitutional Medicine
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• v.14 no.1
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• pp.90-99
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• 2002

Exact constitutional classification is especially important in Sasang Constitutional Medicine. Therefore, most studies on the Sasang Constitutional medicine have been focused on how accurately to classify Sasang Constitution. Recently, there have been reported on the studies about relationship between genetic polymorphism and Sansang Constitution. The purpose of this study is to investigate whether there is any correlation between Sasang Constitution and HLA type. Polymorphism of HLA genes have been known to be important role in transplantation, autoimmune disease, immune response against infection. This study was concentrated on a relationship of HLA-A, -C, -DR, and -DQ types with Sasang Constitution. Results are as following. 1. In the case of HLA-A, there was no significant difference. Only $HLA-A^*31$ has a tendency which Soyangin is less frequent than Soeumin and Taeumin. 2. In the case of HLA-C, there was significant difference between Sasang Constitution and HLA type. In persons having $HLA-C^*04$ allele, Taeumin is more frequent than Soyangin and Soeumin. On the other hand, Soyangin is more frequent than Taeumin and Soeumin in $HLA-C^*07$ allele. $HLA-C^*14$ has a tendency which Soeumin is more frequent than Soyangin and Taeumin. 3. In. the case of HLA-DR type and HLA-DQ type, there was no significant difference among Sansang Constitution. On the study of correlation between Sasang Constitution and HLA type, there was little statistical significance and tendency. This study was the first try about presentation of frequency on the HLA alleles corresponding with Sasang Constitution. I think that more study on the relationship between HLA gene and Sasang Constitution is necessary by method of large case research and various statistical analysis.

• Journal of Sasang Constitutional Medicine
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• v.34 no.2
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• pp.1-14
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• 2022

Objectives The aim of this study was to investigate the change in Sasang constitution prediction value in 2 years and find the factors associated with it. Methods Cohort data from Korean medicine data center was used. Using Korean Sasang Constitutional Diagnostic Questionnaire (KS-15) which consist of questions related to body shape, temperament, and symptoms, participants were categorized into Tae-Yang (TY), Tae-Eum (TE), So-Yang (SY), and So-Eum (SE). Sasang constitution was assessed on the baseline and after two years. Result Total 5,784 participants were analyzed. (TE 3, 341; SE 911; SY 1,532). Among them, 1,402 participants (24.2%) showed different prediction value in KS-15 after two years. The proportion of participants showing different prediction value in two years was the highest in SY, and the lowest in TE group. The factors associated with the change in Sasang constitution prediction value were different by constitution type. The change in feeling after sweating was significantly associated with the change in prediction value in TE and SY groups, not in SE group. Although temperament was not significantly associated with the change in prediction value from TE to SE, it was significantly associated with that in the change from TE to SY. The change in BMI and appetite were associated with the change in constitution prediction value in all three constitution types. Conclusion Although the factors associated with the change in prediction value of Sasang constitution were different by each constitution type, BMI and appetite were significant in all three types. These factors could be useful for developing Sasang constitution questionnaire and deciding re-prediction needs of Sasang constitution. Further research about the factors related to Sasang constitution diagnosis need to be conducted.

• Journal of Sasang Constitutional Medicine
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• v.12 no.2
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• pp.78-93
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• 2000

The problem lies in 'Sasang Constitution Medicine' is a subjectiveness of diagnosis that the result of diagnosis varies according to the doctors. In order to supplement to this demerit, multiple approach has done to diagnose objectively. This study has focused on evaluating the effectiveness and accuracy of the questionnaire which considered as a basic data to identify constitution By analysing the tendency of the respondents who has defined constitution by clinical diagnosis and comparing of their answers, the result of their constitution analysis by our questionnaire were re-examined. The answer of each question to each constitution were tested how it is relevant to a scale of a constitution. As a result, we have found that there is limitation to find out constitution by the questionnaire we used, one we hope that suitable questionnaire will be developed for the research in the future

• Journal of Sasang Constitutional Medicine
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• v.18 no.1
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• pp.118-131
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• 2006

1. Objective Pulse diagnosis is generally applied to Traditional Oriental Medicine but not to Sasang Constitution diagnosis. Recently new pulse analyzer using array piezoresistive sensor and multi-channel robot arm developed. It reflects Oriental Medical Doctors' diagnostic processes, and its reproducibility test was done at Korea Institute of Oriental Medicine. We performed this study to set parameters diagnosing Sasang Constitution. 2. Methods One hundred thirty three subjects participated in this study. They are healty and approved this study. Before being tested with pulse analyzer, they had interview with Sasang Constitution Specialist to diagnose their Sasang Constitution. We established some useful parameters from parameters of pulse analyzer according to the Original Texts of Oriental Medicine and clinical experiences to analyze with clinical data of this study. 3. Results (I) There is a significant difference in pre-dicrotic notch time among all parameters of pulse analyzer in Sasang Constitution groups(P=0.047). (2) There is a significant difference in maximum pulse pressure in 33 to 48 year Sasang Constitution groups(P=0.010). (3) There is a significant difference in frequency width in 17 to 32 year Sasang Constitution groups(P=0.002). (4) There is a significant difference in CFS value in groups which OMD diagnoses; Floating & Sinking pulse(P=0.020). (5) There is a significant difference in pulse rate in groups which OMD diagnoses; Rapid & Slow pulse(P=0.000). (6) There is a significant difference in maximum pulse pressure in groups which OMD diagnoses; Deficient & Solid pulse(P=0.000). 4. Conclusions Analyzing parameters in each Sasang Constitution group, we found it shows significant difference in maximum pulse pressure and corresponding tendency in coefficient of floating & sinking pulse with theories of Sasang Consti-tutional Medicine. As we accumulate more clinical data, we will establish algorithm to diagnose Sasang Constitution using a pulse analyzer.

• Journal of Sasang Constitutional Medicine
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• v.16 no.1
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• pp.112-119
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• 2004

Objectives This paper was designed for studying the features of digestion according to Sasang Constitution and to be helpful to make a diagnosis Sasang Constitution. Using the result of this study, it will be helpful to diagnose a Sasang constitution. Methods There were 588 patients(248 men, 340 women) who answered questionnaire and were diagnosed by the Sasang Constitution Specialist at Constitutional Clinic of Dongguk Bundang Oriental Hospital. Using the response of questionnaire and several statistical techniques such as homogeneity test and multiple comparison, we tried to find the characteristics of each constitution depending on its dining behavior. Results As a result of the analysis of questionnaire, Taeumin and Soyangin answered to 'Because digestion is well, I overeat frequently' many more than Soeumin(p<0.01). Soeumin answered to 'When I eat cold food or greasy food, it hardly digests' many more than Taeumin(p<0.05). Soeumin and Taeyangin answered to 'Because I have indigestion, I have suffered from infancy' many more than Taeumin(p<0.01). Soeumin answered to 'I have easily a digestive upset' many more than Taeumin(p<0.01). Soeumin answered to 'indigestion in case of paying attention' many more than Taeumin and Soyangin(p<0.01).

• Journal of Sasang Constitutional Medicine
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• v.13 no.3
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• pp.40-51
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• 2001

1. Purpose : The research is study to classify the clinical symptoms of the diabetes mellitus according of the Sasang constitution. that is used to treat and manage the diabetics. 2. Method : We collected 69 patients with diabetes who were diagnosed Sasang constitution at department of Sasang constitutional Medicine in Dongeui Oriental Hospital during 1 year from August. 2000 to July. 2001. and then we investigated and analyzed the clinical symptoms of the diabetics according of the Sasang constitution 3. Result and conclusion We investigated the clinical symptoms of the diabetes according of the Sasang constitution to find relationship between the symptoms and the Sasang constitutions. The result of it, we found that it is different between the symptoms according of the Sasang constitution in first symptoms of the diabetes mellitus, weight, appetite, urine and drinking water. Therefore we have found that it is possibility to classify the clinical symptoms of the diabetes mellitus patients according of the Sasang constitution.

• Journal of Society of Preventive Korean Medicine
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• v.12 no.2
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• pp.115-130
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• 2008

It is very important problem that exactly distinguish constitution, in Sasang constitutional Medicine. But, it is careless that discuss the propriety of 'Sasang constitution unchangeability theory(四象體質 不變論)'. The foundation of Sasang constitution unchangeability theory is the sentence in DongUi SuSae BoWon Sa-dan theory(東醫壽世保元 四端論) : "The Organ system of Taeyang(太陽), Taeum(太陰), Soyang (少陽) and Soeum(少陰) is the variation of YinYang(陰陽), is firm nature and is unnecessary agreement. (太少陰陽之臟局 陰陽之變化也 天稟之已定 固無可論)". But, the foundation of Sasang constitution unchangeability theory contradict the theory that Organ system(臟腑) is made by deviation of emotions(joy, anger, sorrow and pleasure :喜怒哀樂) or temperament(性情). Because these emotions is revealed after birth(後天), the deviation of Organs system made by deviation of emotions is not innate, is acquired after birth. Therefore, it is necessary to discuss the opinion that Sasang constitution is variable after birth. The conclusion of our study is that Sasang constitution can be variable after birth.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.3
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• pp.729-735
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• 2005

This study was to analyze the difference between blood type and blood constitution according to Sasang constitution. The subjects were 302 men who visited blood donation house. Data collection was performed by using questionnaire that included three types of Sasang constitution. The data were analyzed as frequency, percentage, ${\chi}$2-test and ANOVA using SPSS 10.0 WIN Program. There was significant difference statistically in frequency of blood type as per Sasang constitution(${\chi}$2 =53.254, p=.000). Soyangin got most number in B type(34.7%), O type(26.7%), A type(21.8%), AB type(16.8%) in order. Taewumin got most number in O type (45.8%), A type(31.3%), B type(22.1%) and AB type(0.8%) in order, and in case of Sowumin, most in A type(54.3%), B type(24.3%), O type (11.4%) and AB type(10.0%) in order. In weight, height, fatness, hemoglobin, Hematocrit, platelet, ALT, AST and cholesterol, it appears that there is significant difference according to Sasang constitution. If proper regimen according to Sasang constitution by grasping the special features as per Sasang constitution through analyzing the difference as per Sasang constitution based on the results of above study is applied.

• Journal of Sasang Constitutional Medicine
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• v.19 no.3
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• pp.144-155
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• 2007

1. Objectives The purpose of this study was to find the difference of ordinary and pathological symptoms according to Sasang Constitution. 2. Methods We recruited 418 subjects in the five oriental hospitals and researched normal symptoms and illness ones through a paper, who were diagnosed by the Sasang Constitution specialist in oriental hospital, who had remarkable improvement in their chief complain after Sasang Constitution medication. 3. Results 1) In ordinary symptoms, amount, speed and appetite items of Digestion are significantly different according to Sasang Constitution statistically(p<0.05). Feeling after evacuation of Feces, feeling after urination and yellow color of Urine, amount, feeling after sweat, location in hand/feet of Sweat, and in the others, Tireness in head, Drinking water, sensitivity, coldness in hand/feet, warmness in belly of Coldness/Warmness are also significantly different(p<0.05). 2) In pathological symptoms, palpitation, swelling and lack of appetite items are significantly different according to Sasang Constitution statistically(p<0.05). 3) In diseases, Hypertension and DM items are significantly different according to Sasang Constitution statistically(p<0.05). 4. Conclusions There were significantly difference items in ordinary, pathological symptoms and diseases according to Sasang Constitution.