• 대한한방내과학회지
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• 제37권5호
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• pp.885-892
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• 2016

Few studies have reported the effects of traditional Korean medical (TKM) therapy in patients with traumatic brain hemorrhage. The patient was a 93-year-old female who was unconscious after a traumatic intracerebral hemorrhage (ICH) and was not a candidate for any surgical treatment because of her age. We treated her with acupuncture and herbal medicine. After 28 days of treatment, we observed an improvement in consciousness on the Glasgow Coma Scale (GCS) and in other symptoms (aphasia, weakness in both legs, and headache).

• 대한한의학원전학회지
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• 제22권3호
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• pp.1-6
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• 2009

"Byeonjeungbang-yakjeongjeon(辨證方藥正傳)" was written in the year of 1946 by Lee Sanghwa(李常和) by adding on the original "Bang-yakhappyeon(方藥合編)". 850 formulas based on experience from the times of old and present were added to the original 588 of "Bang-yakhappyeon" and Kimsamul(金四物)'s Samultang(四物湯) modification[加減], Yun Chochang(尹草窓)'s Ijintang(二陳湯) and Pyeong-wisan(平胃散) modification, Idongwon(李東垣)'s Bojung-ikgitang(補中益氣湯) modification, and Pung(馮)'s Yukmijihwangtang(六味地黃湯) modification were added. The 60 medical texts that he consulted greatly influenced the formulas that were added, and of those books the ones of interest include "Seoksilbirok(石室秘錄)", "Byeonjeungrok(辨證錄)", "Byeonjeunggimun(辨證奇聞)" and "Bucheongjunamnyeogwa(傅靑主男女科)". If we analyze the 850 formulas of "Byeonjeungbang-yakjeongjeon", 290 of them, 34%, are related to Jinsatak(陣士鐸)'s medical texts, and of those 290, 15 are from "Seoksilbirok"(5%), 49 are from "Bucheongjunyeogwa"(17%), and 226 are from "Byeonjeungrok"(78%). So, the added formulas of Leesanghwa's "Byeonjeungbang-yakjeongjeon" have been greatly influenced by Jinsatak(陳士鐸), and by looking through Jin(陳)'s medical ideas one can find the origin of prescriptions and become more flexible.

• 대한한의학원전학회지
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• 제31권4호
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• pp.69-78
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• 2018

Objectives : The aim of this study was to diversify the interpretation of formulas used for insomnia treatment by searching and analyzing herbal combinations in formulas used for insomnia treatment in Korean medicine. Methods : Frequency analysis was conducted on herbal combinations of 255 formulas related with insomnia, along with network analysis using Netminer 4.2.1. Results : This study has found herbal combinations used frequently in Korean medicine formulas used for insomnia treatment, and a result of network analysis composed of four communities. Each community consisted of herbs in affiliation of Yookmijihwangtang(六味地黃湯) and Samultang(四物湯), Bohyulchunghwatang(補血淸火湯) and Ondamtang(溫膽湯), Jungjihwan(定志丸) and Sanjointang(酸棗仁湯). Conclusions : This study could help in assisting researchers to diversify formula analysis in future studies. Moreover, the herbal combination in insomnia formulas could be used to search for insomnia formulas in other databases or creating a new prescription.

• 대한한방내과학회지
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• 제12권1호
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• pp.31-44
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• 1991

Review of literature on languor and fatigue. According to comparative studies of Oriental and Western medical literature on languor and fatigue of treatment, following results were obtained. 1. Treatment of languor and fatigue in Western medicine were firstly treatment of an organic disease, secondly inhalation of massage, bathing, sleeping, balance 02 of a motion, dosage, supply of a nutrition and the others. 2. On the treatment of languor and fatigue in oriental medicine, the methods of treatment were an warming and supplement the vital energy, tranquilization and nourishment, and the prescriptions were Samultang, Sagunja tang, palmultang, Yoogkunjatang, Gongjindan, SSanghwatang, Dogsamtang, yoogmijihwangwon, sungyangikgitang, Samchulgeonbitang and the others.

• 한방안이비인후피부과학회지
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• 제34권4호
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• pp.228-236
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• 2021

Objective : The purpose of this study is to report the clinical effectiveness of herbal decoction(Samul-tang hap Soyo-san.) on whole body nummular eczema. Method : A patient suffering from nummular eczema received herbal decoction(Samul-tang hap Soyo-san), acupuncture, and electronic-moxibustion treatment. The effectiveness of treatment was evaluated by EASI, DLQI, photography and subjective evaluation of the patient's improvement of symptoms. Results : After treatment, eczema lesions were remarkably improved. Compared to its peak, EASI improved by 69% and DLQI by 53%. According to photo and symptom changes, purulent exudates were stopped and pruritus was decreased. Conclusion : This study suggests that Samul-tang hap Soyo-san could show effectiveness on nummular eczema.

• 대순사상논총
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• 제39집
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• pp.249-274
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• 2021

本文乃以韓國大巡真理會《典經》為主, 探討姜甑山的宗教醫療。姜甑山的醫療原理建立在「身心一體」的整體觀, 意即醫治疾病, 必先醫心, 也就是他所說的「大病之藥, 安心安身」。按摩是姜甑山經常運用的物理治療, 他運用按摩消除病患因氣鬱不順所導致腿部與腹部的諸多疾病 ; 而四物湯, 小柴胡湯, 木瓜, 生地黃是他常用的藥劑與藥材。道法醫療是姜氏宗教醫療的特色, 根據《典經》的記錄, 有正氣祛病, 驅除精怪, 代病與轉病, 更衣除病, 用藥於地等, 結合符咒, 藉以醫治百姓, 尤其用藥於地是他獨創的道法醫療方式。

• 대한예방한의학회지
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• 제19권3호
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• pp.103-113
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• 2015

Objective : Five most generally adopting basic oriental prescriptions (yookmijihwangtang, ojeoksan, sipjeondaebotang, samultang, bojoongikgitang) samples were collected from 10 oriental hospitals nationwide and the transferring ratio to aqueous phase (TRAP) were calculated. Method : The samples are grounded evenly and the decocted at $120^{\circ}C$ for 12 min on hot plate and then filtered. The concentrations of As, Cd, Co, Cr and Pb in before and after decoction were measure by ICP/MS and the TRAPs were calculated. Results : The concentrations of As, Cr and Pb in the ground samples before decoction were all below criteria level, and TRAP values were also very low (<10%). For Cd, although some ground samples before decoction showed relatively high concentration level compare to the criteria level, because of their low TRAP (~3%), the actual concentrations in the decoction were quite low compare the criteria level. The Co's concentrations in the ground samples before decoction were all relatively low level. However, the TRAP of Co was astonishingly high value of around 40% average. Conclusion : The toxic heavy metal concentrations in the decoction were very low compare to the criteria level. The TRAPs are less than <10% except Co. The toxic heavy metals in the prescriptions are mainly remained in the residue and the only very small fraction may transferred to the decoctions. Therefore the toxicity of the oriental herbal medicine about the toxic heavy metal may be overstressed. The Co's TRAP turned out to be quite high value (40% average). Since the criteria level wes not established yet, the safety of decoctions according to Co was not fully confirmed.

• 대한한방소아과학회지
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• 제18권1호
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• pp.105-129
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• 2004

Methods: It was studied on the 47 kinds of oriental medical literature for fecal blood. Results: Fecal blood means bleeding with faces from anus and indicates all the three cases such as blooding before and after evacuation, evacuation of feces mixed with blood, and simple melena. The main causes are fire(火) and deficiency of spleen qi (脾氣虛). According to the color of fecal blood and the region of the bleeding, first, if the blood color is dark-red and blood discharges after emptying the bowels, it is called deposited poison into Jang(臟毒) or distant bleeding(遠血), and if the color of blood is clear and bowel emptying occurs after bleeding, it is bloody stool due to intestinal wind(腸風) or nearby bleeding(近血). For treating methods(治法). removing heat from the blood and stopping bleeding(淸熱凉血止血), removing dampness and stopping bleeding(淸熱除濕止血), invigorating Ki for promoting Hul-controJ(益氣攝血), warming the spleen and stomach to dispel cold and stopping bleeding(溫中散寒止血) etc are applied. As for the treating prescriptionl(治法), a Hwangtotang(黃土湯). Jeoksodudanggwitang(赤小豆當歸散). Gwihwasan(槐花散). Wipungtang(胃風湯). Hwangnyeonhwan modifying(黃連丸加減). Samultang modifying(四物湯加減). Paedoksan modifying(敗毒散加減) etc are used. As for acupuncture and moxibustion(鍼灸療法). if etiology(病因) is damp-heat(濕熱), acupuncture(刺鍼) at Janggang(長强); Charyo(BL 32); Sangeoheo(ST 37)(上巨虛); Seungsan(BL 57)(承山穴), and in case of deficiency of spleen Gi(脾氣虛), acupunture(刺鍼) with tonification(補法) at I Baek(EX-UE 2)(二白); Gwanwon(CC 4)(關元); Joksamni(ST 36)(足三里) Taebaek(SP 3)(太白); Hoeeum(CC 1)(會陰穴), or mxibuston(灸) at Baekoe(GC 2O)(百會); Myeongmun9GC (命門) or the point of opposite to umbilicus among spinal vertebrae(脊中對臍穴) are used. The external treatment(外治療法) was consisted of plastering umbilicus therapy(敷臍法) and enema therapy(灌腸法).

• 대한한방내과학회지
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• 제21권4호
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• pp.535-542
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• 2000

The water extracts of Samul-tang(SMT) has been used for treatment of ischemic brain damage in Oriental traditional medicine. However, little is known about the mechanism by which the water extracts of SMT rescues brain cells from ischemic damages. To elucidate the protective mechanism on ischemic induced cytotoxicity, I investigate the regulation of LPS and PMA induced iNOS expression in C6 glial cells. LPS and PMA treatment for 72 h in C6 glial cells markedly induce nitric oxide(NO), but treatment of the cells with the water extracts of SMT decrease. dose dependently nitrite formation. In addition, LPS and PMA treatment for 72 h induce severe cell death and LDH release in C6 glial cells. However treatment of the cells with the water extracts of SMT dose not induce significant changes compare to control cells. Furthermore, the protective effects of the water extracts of SMT is mimicked by treatment of $N^{G}MMA$, a specific inhibitor of NOS. LPS and PMA induced iNOS activation in C6 glial cells cause chromosomal condensation and fragmentation of nuclei by caspase activation. The treatment of the cells with the water extracts of SMT may suppress apoptosis via caspase inhibition by regulation of iNOS expression. Taken together, I suggest that the protective effects of the water extracts of SMT against ischemic brain damages may be mediated by regulation of iNOS during ischemic condition.

• 대한한의학방제학회지
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• 제11권1호
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• pp.129-149
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• 2003

Liver is an important target of the toxicity of drugs, xenobiotics and oxidative stress. Acetaminophen pverdose causes acute liver injury in both humans and animals. This study was performed to observe the effect of sachunwhan and its component groups on recovery of hepatoxicity in acetaminophen treated rats. The experimental group was divided into 4 groups: sachungwhan(SC), samultang group(SC-1: 當歸, 川芎), chungyul group(SC-2: 龍膽草, 大黃, 梔子), and haepyo group(SC-3:羌活, 防風). Under the same condition Normal group was fed basal diet and water; Control group was injected acetaminophen and fed basal diet for 2 weeks; Experimental groups were injected acetaminophen and fed each extracts for 2 weeks respectively. The results were obtained as follows: 1. In the study on antioxidative defense system in vivo, SC reduced the amount of lipid peroxide in both serum and liver and showed activity on antioxidative enzymes such as catalase, glutathion. Other groups had effect only on glutathion. 2. In the study on hepatotoxicity(GOT, GPT, ${\gamma}$-GTP, ALP, LDH, Bilirubin), SC had a significant effect on recovery of hepatoxicity in acetaminophen treated rats. Other groups had no effect except SC-1 having effect on ${\gamma}$-GTP. As results shown, only Sachungwhan(SC) has significant effects on recovery of hepatoxicity and antioxidative defense system in vivo. These results suggest that Sachungwhan(SC) made antioxidative defense system active and it seemed to be very important to its effect on recovery of hepatoxicity. In the other hand, Component groups had no effect on recoverv of hepatoxicity and antioxidative defense system in vivo. This was thought that component drugs' cooperative synergy effect would be important to Sachungwhan(SC)'s effects mentioned in this paper.