• Journal of Pharmaceutical Investigation
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• 제39권3호
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• pp.217-219
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• 2009

There are several approaches to calculate a sample size for bioequivalence test. Among these approaches, sample sizes determination based on Schuirmann's two one-sided tests procedures has been used most popularly in case of 2${\times}$2 bioequivalence study. Here we proposed simple sample size table for conventional 2${\times}$2 bioequivalence test based on Schuirmann's two one-sided tests in accordance with Korean Guidelines for Bioequivalence Test. This table will allow researchers with a little statistical background to calculate the sample size for bioequivalence with easy process.

• 한국전기전자재료학회논문지
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• 제28권7호
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• pp.456-461
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• 2015

In this study, the frequency properties of electrostatic capacity and dielectric loss for the samples with different types of filler has been measured in through the applied frequency range of 7 kHz ~3,000 kHz at temperature of $80^{\circ}C$, $110^{\circ}C$, $140^{\circ}C$, $170^{\circ}C$. The results of this study are as follows. When the sample is degradated at the temperature of $80^{\circ}C$, $110^{\circ}C$, $140^{\circ}C$, $170^{\circ}C$ and the frequency range of 7 kHz ~3,000 kHz is applied, It found that the electrostatic capacity of the sample with Polyimide film is larger than the sample with Grass fiber. It found that the dielectric loss for the sample with Polyimide film is larger than the sample with Grass fiber with increasing frequency and temperature in the $80^{\circ}C$, $110^{\circ}C$, $140^{\circ}C$, $170^{\circ}C$ range. Also, the dielectric loss decreased with increasing frequency. In case of the sample with Polyimide film, It found that the electrostatic capacity decreased with increasing temperature, and the dielectric loss gradually decreased with increasing frequency.

• 한국수학교육학회지시리즈A:수학교육
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• 제45권2호
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• pp.145-154
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• 2006

The main purpose of this study is to investigate the effect of departures from normality and equal variance on the two-sample test when the variances are unknown. We have found that type I error brought about a little bit change which is ignorable in relation to kurtosis. But the change of type I error was mainly based on the skewness of the parent population. In introductory statistics classes where data analysis includes techniques for detecting skewness of two populations, we recommend the two-sample t-test when maximal skewness of two populations is smalter than the value 4 when the variances seem equal. Furthermore, our simulations reveal that the two-sample t-test appears somewhat more robust than that of z-test if the assumption of equal variance is satisfied. In the case of unequal variance, the two-sample t-test appears somewhat more robust provided the t-statistic using Satterthwaite's approximate degrees of freedom.

• Journal of the Korean Data and Information Science Society
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• 제11권1호
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• pp.83-90
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• 2000

이원분할표의 두 범주형 변수에 대한 독립성을 검정할 때 흔히 카이제곱 검정통계량이 사용된다. 표본추출 모형이 다항이나 곱다항인 경우 이 검정통계량이 독립성 가정하에서 근사적으로 카이제곱 분포를 따르게 되는 것은 잘 알려진 사실이다. 두 주변값이 모두 주어진 경우 독립성 가정하에서 표본추출 모형은 다중 초기하분포가 되며 앞의 모형과 마찬가지로 카이제곱 통계량에 근거한 검정을 사용할 수 있다. 이 연구에서는 주변값이 주어진 경우에 카이제곱 통계량의 소표본 분포를 대표본 분포인 카이제곱 분포와 비교하고자 한다. 표본크기가 작은 몇 개의 경우에 대해 카이제곱 통계량의 소표본 분포를 직접 계산해보았다. 표본크기가 큰 몇 개의 경우는 간단한 몬테칼로 알고리듬을 통해 소표본 분포를 생성하고 카이제곱 확률도와 콜모고로브-스미노브 단일표본 검정을 이용하여 대표본 분포와의 일치성을 알아보았다.

• 한국식품조리과학회지
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• 제13권3호
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• pp.356-363
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• 1997

Soybean Da-sik was prepared with various soybean powder processing methods (roasting, steaming, and steaming followed by roasting) and sugar types (honey, oligo-sugar), and their sensory and physical characteristics were evaluated to determine the optimum preparation method. The results were as follows: 1. For Sample 1 (roasting soybeans for 30 min at 150$^{\circ}C$ and grinding), the best appearance of Da-sik was obtained when the content of honey was adjusted to 35 g, and the color with 30 g of oligo-sugar by sensory evaluation. The optimum texture was obtained with 40 g of honey, and the optimum chewiness with 30 g of honey Overall, the optimum quality was obtained with 35 g of honey, and oligo-sugar seemed to have less influence on the quality. In case of Sample 2 (four rounds of steaming and drying for 35 min), 40 g of oligo-sugar was found to exhibit the best quality, and honey was less effective. For Sample 3 (three rounds of drying followed by 15 min roasting at 150$^{\circ}C$), the best appearance and color were obtained with 35 g and 40 g of honey, respectively. The texture was most favorable with 40 g of honey, while the chewiness was best with 30 g of honey, suggesting 35 g of honey was the optimum level for Sample 3 soybean powder than oligo-sugar. 2. The springiness, gumminess, hardness and chewiness measured by a texture analyser were highest with Sample 1 containing 30 g of honey, and the cohesiveness with 40 g of honey. 3. For color, the best brightness and yellowness were obtained with Sample 1 with 30 g of honey. The redness was highest with Sample 3 with 40 g of honey. Overall, the desirable recipe for soybean Da-sik was 35 g of honey for Sample 1 and Sample 3, and 40 g of oligo-sugar for Sample 2.

• Journal of the Korean Wood Science and Technology
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• 제17권2호
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• pp.26-33
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• 1989

The acoustic absorption coefficient and acoustic impedance of 5 species of softwood(sonamoo, sam namoo, gusang namoo, hwaback, sitka spruce) and 5 species of hardwood (Mulgusul namoo, Italian popular, white meranti, red meranti, kalantas) were measured by the standing wave method. which is simple in the setup and gives more accurate result than does any other measuring method. The dependence of the absorption coefficient and complex acoustic impedance on the wood sections. thickness of the sample itself and the back air gap was investigated experimentally in the frequency range from 200Hz to 1800Hz, and the result are as follows: 1. The acoustic absorption coefficient of wood sections was higher on the cross section than radial and tangential sections. 2) The acoustic absorption coefficient were higher in the frequency range from 400Hz to 600Hz, but decreased in the frequency above 600Hz. 3. The genenal tendency of the variation of the normal acoustic impedance was increased according to the frequency. 4. The acoustic absortion coefficient was increased in the to 7mm-thick sample and decreased in 9mm-thick sample. 5. The higher acoustic absorption coefficient was shown in the case with the backing an gap than in the case without the gap.

• Environmental Analysis Health and Toxicology
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• 제29권
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• pp.19.1-19.10
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• 2014

Objectives Lysosome is the cell-organelle which is commonly used as biomonitoring tool in environmental pollution. In this study, the lysosomal proteomic of the yeast Saccharomyces cerevisiae was analyzed for utilization in the detection of toxic substances in mine water samples. Methods This work informs the expression of lysosomal proteomic in yeast in response with toxic chemicals, such as sodium meta-arsenite and tetracycline, for screening specific biomarkers. After that, a recombinant yeast contained this biomarker were constructed for toxic detection in pure toxic chemicals and mine water samples. Results Each chemical had an optimal dose at which the fluorescent protein intensity reached the peak. In the case of water samples, the yeast showed the response with sample 1, 3, 4, and 5; whereas there is no response with sample 2, 6, and 7. Conclusions The recombinant yeast showed a high ability of toxic detection in response with several chemicals such as heavy metals and pharmaceuticals. In the case of mine water samples, the response varied depending on the sample content.

• 한국자동차공학회논문집
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• 제20권4호
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• pp.133-141
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• 2012

This study investigates structural and fatigue analyses of bike brake. Maximum equivalent stress of the model of mountain bike is 4 times as much as the model of general bike at static analysis. In cases of mountain and general bikes, maximum damage frequency at load of 'SAE bracket history' with the severest change of load becomes as much as 16 times than the most stable load of 'Sample history' among the nonuniform fatigue loads. In case of mountain bike, the possibility of maximum damage becomes 3% at the load of 'Sample history' with the average stress of 0 to $-3{\times}10^4$MPa and the amplitude stress of 0 to $10^4$MPa. In case of general bike, the possibility of maximum damage becomes 3% at the load of 'Sample history' with the average stress of 0 to $-0.8{\times}10^4$MPa and the amplitude stress of 0 to $0.2{\times}10^4$MPa. This stress state can be shown as 5 to 6 times more than the damage possibility of 'SAE bracket history' or 'SAE transmission'. The analysis result of this study can be effectively utilized for the safe design of bike brake.

• 약학회지
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• 제10권4호
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• pp.1-6
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• 1966

Various thiocyanatoammine chromium complex salts are prepared by the known methods and the Rf. value of these complex salts are determined by four developers. These four developers were used in the paper chromatographical work of cobalt complex salts by Yamamoto in 1954. It was also found that the developer A (Ch$_{3}$OH, acetone, NH$_{4}$OH) gave best results of these four developers and the decending development gave better results than ascending development in this experiment. In the case of decending development using developer A, it is found that the Rf. value is increased with the number of thiocyanate radical. The reason of this curious results can be explained that the thiocyanate radical in the complex ion is more active for the organic solvent than ammine radical. Shifting of electrons to the central metal and the charge of the complex ion can also effect ot the Rf. value but much questions are remained for the explanation of the above curious phenomenon. Separation of mixed sample is also studied for various mixture of the above complex salts. In the case of the mixture of hexammine and diammine complex salt, the clear separation is possible but in almost all other mixed sample, the results are not clear. Therefore it can be said that the results of this work can be used in the qualitative analysis of the individual complex salts, except the mixed sample of hexammine and diammine complex salts.

• Communications for Statistical Applications and Methods
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• 제18권4호
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• pp.477-483
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• 2011

This article is concerned with a class of threshold-asymmetric GARCH models both for stationary case and for non-stationary case. We investigate large sample properties of estimators from QML(quasi-maximum likelihood) and QL(quasilikelihood) methods. Asymptotic distributions are derived and it is interesting to note for non-stationary case that both QML and QL give asymptotic normal distributions.