• Title/Summary/Keyword: Sample Accumulation Method

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Electrochemical Investigation of Bovine Hemoglobin at an Acetylene Black Paste Electrode in the Presence of Sodium Dodecyl Sulfate

  • Zhan, Guoqing;Li, Chunya;Luo, Dengbai
    • Bulletin of the Korean Chemical Society
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    • v.28 no.10
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    • pp.1720-1724
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    • 2007
  • Electrochemical behaviors of bovine hemoglobin (Hb) at an acetylene black paste electrode based on the enhancement effect of sodium dodecyl sulfate (SDS) were investigated. In the optimal conditions, a very weak reduction peak was observed at an acetylene black paste electrode for hemoglobin in the absence of SDS. However, the reduction peak current increased remarkably after the addition of 4.0 × 10?4 mol L?1 SDS, suggesting that SDS exhibits obvious enhancement effect to the determination of hemoglobin. All the experimental parameters, such as pH value, concentration of SDS, accumulation time and accumulation potential were optimized for hemoglobin analysis. The proposed method possesses high sensitivity (detection limit is 3.0 × 10?9 mol L?1), wide linearity (6.0 × 10?9 to 6.0 × 10?7 mol L?1), rapid response and low cost. Finally, the method was successfully employed to determine hemoglobin in a spiked sample.

A Simulation Sample Accumulation Method for Efficient Simulation-based Policy Improvement in Markov Decision Process (마르코프 결정 과정에서 시뮬레이션 기반 정책 개선의 효율성 향상을 위한 시뮬레이션 샘플 누적 방법 연구)

  • Huang, Xi-Lang;Choi, Seon Han
    • Journal of Korea Multimedia Society
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    • v.23 no.7
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    • pp.830-839
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    • 2020
  • As a popular mathematical framework for modeling decision making, Markov decision process (MDP) has been widely used to solve problem in many engineering fields. MDP consists of a set of discrete states, a finite set of actions, and rewards received after reaching a new state by taking action from the previous state. The objective of MDP is to find an optimal policy, that is, to find the best action to be taken in each state to maximize the expected discounted reward of policy (EDR). In practice, MDP is typically unknown, so simulation-based policy improvement (SBPI), which improves a given base policy sequentially by selecting the best action in each state depending on rewards observed via simulation, can be a practical way to find the optimal policy. However, the efficiency of SBPI is still a concern since many simulation samples are required to precisely estimate EDR for each action in each state. In this paper, we propose a method to select the best action accurately in each state using a small number of simulation samples, thereby improving the efficiency of SBPI. The proposed method accumulates the simulation samples observed in the previous states, so it is possible to precisely estimate EDR even with a small number of samples in the current state. The results of comparative experiments on the existing method demonstrate that the proposed method can improve the efficiency of SBPI.

A study on the computer diagnosis that apply Neural-Fuzzy algorithm accumulation detection of Partial Discharge signal (부분방전 신호의 누적검출과 뉴럴-퍼지 알고리즘을 이용한 컴퓨터 진단에 관한 연구)

  • Hwang, Kyoung-Jun;Yeoum, Keoung-Tae;Kim, Yong-Kab;Kim, Jin-Su
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.1445-1446
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    • 2007
  • In this paper, we have studied for analysis of the partial discharge(PD) signal in power transmission line. The PD signal has estimated as detected signal accumulation of a PRPDA method by using Labview, and analyzed with neural-fuzzy algorithm. With practical PD logic implementation of theoretical detected system and hardware implementation, the device for Hipotronics Company's 22.9kV or 154kV setup have generated and then have applied with 18kV,20kV with 1:1 time probe. It's also used the LDPE 0.27mmt (scratch error 0.05mmt) to sample for making PD. Our new class of PD detected algorithm have also compared with previous PRPDA or Neural Fuzzy algorithm, which has diagnose more conveniently by adding numerical values.

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Comparative Investigation of Interfacial Characteristics between HfO2/Al2O3 and Al2O3/HfO2 Dielectrics on AlN/p-Ge Structure

  • Kim, Hogyoung;Yun, Hee Ju;Choi, Seok;Choi, Byung Joon
    • Korean Journal of Materials Research
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    • v.29 no.8
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    • pp.463-468
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    • 2019
  • The electrical and interfacial properties of $HfO_2/Al_2O_3$ and $Al_2O_3/HfO_2$ dielectrics on AlN/p-Ge interface prepared by thermal atomic layer deposition are investigated by capacitance-voltage(C-V) and current-voltage(I-V) measurements. In the C-V measurements, humps related to mid-gap states are observed when the ac frequency is below 100 kHz, revealing lower mid-gap states for the $HfO_2/Al_2O_3$ sample. Higher frequency dispersion in the inversion region is observed for the $Al_2O_3/HfO_2$ sample, indicating the presence of slow interface states A higher interface trap density calculated from the high-low frequency method is observed for the $Al_2O_3/HfO_2$ sample. The parallel conductance method, applied to the accumulation region, shows border traps at 0.3~0.32 eV for the $Al_2O_3/HfO_2$ sample, which are not observed for the $Al_2O_3/HfO_2$ sample. I-V measurements show a reduction of leakage current of about three orders of magnitude for the $HfO_2/Al_2O_3$ sample. Using the Fowler-Nordheim emission, the barrier height is calculated and found to be about 1.08 eV for the $HfO_2/Al_2O_3$ sample. Based on these results, it is suggested that $HfO_2/Al_2O_3$ is a better dielectric stack than $Al_2O_3/HfO_2$ on AlN/p-Ge interface.

Multi-class Analysis of Exposure Chemicals in Deciduous Teeth by Liquid Chromatography-Mass Spectrometry: Preliminary Studies on Sample Preparation Methods

  • Lee, Yujin;Seo, Eunji;Park, Jun Young;Bae, Kwang-Hak;Lee, Jaeick;Cha, Sangwon
    • Mass Spectrometry Letters
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    • v.9 no.4
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    • pp.110-114
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    • 2018
  • Since accumulation of chemicals in deciduous teeth can occur from the second trimester of fetal development to shedding, a deciduous tooth has been considered as an attractive biomatrix for estimating individual chemical exposures recently. Therefore, detection of organic chemicals from teeth has received an increasing attention in exposomics research. Most previous studies on organic chemical analysis of teeth not only focused on a few targeted chemicals but also ignored potential contaminants from an enamel surface or a dental pulp. Recently, our group started developing a multi-class organic analysis method for deciduous teeth and tried to find a proper incubation condition of tooth materials. Our results showed that incubation with methanolic HCl provided the best performance among tested.

Evaluating the contribution of calculation components to the uncertainty of standardized precipitation index using a linear mixed model (선형혼합모형을 활용한 표준강수지수 계산 인자들의 불확실성에 대한 기여도 평가)

  • Shin, Ji Yae;Lee, Baesung;Yoon, Hyeon-Cheol;Kwon, Hyun-Han;Kim, Tae-Woong
    • Journal of Korea Water Resources Association
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    • v.56 no.8
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    • pp.509-520
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    • 2023
  • Various drought indices are widely used for assessing drought conditions which are affected by many factors such as precipitation, soil moisture, and runoff. The values of drought indices varies depending on hydro-meteorological data and calculation formulas, and the judgment of the drought condition may also vary. This study selected four calculation components such as precipitation data length, accumulation period, probability distribution function, and parameter estimation method as the sources of uncertainty in the calculation of standardized precipitation index (SPI), and evaluated their contributions to the uncertainty using root mean square error (RMSE) and linear mixed model (LMM). The RMSE estimated the overall errors in the SPI calculation, and the LMM was used to quantify the uncertainty contribution of each factor. The results showed that as the accumulation period increased and the data period extended, the RMSEs decreased. The comparison of relative uncertainty using LMM indicated that the sample size had the greatest impact on the SPI calculation. In addition, as sample size increased, the relative uncertainty related to the sample size used for SPI calculation decreased and the relative uncertainty associated with accumulation period and parameter estimation increased. In conclusion, to reduce the uncertainty in the SPI calculation, it is essential to collect long-term data first, followed by the appropriate selection of probability distribution models and parameter estimation methods that represent well the data characteristics.

A Study on Spatial Aggregation Method for Path Travel Time Estimation using Hi-Pass DSRC System (하이패스 DSRC 기반의 경로통행시간 산정을 위한 공간적 집계방안 산정에 관한 연구)

  • Lee, Hwanpil;Shim, Sangwoo;Choi, Yuntaek;Kim, Dongin
    • International Journal of Highway Engineering
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    • v.16 no.3
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    • pp.119-129
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    • 2014
  • PURPOSES : This investigational survey is to observe a proper spatial aggregation method for path travel time estimation using the hi-pass DSRC system. METHODS : The links which connect the nodes of section detectors location are used for path travel time estimation traditionally. It makes some problem such as increasing accumulation errors and processing times. In this background, the new links composition methods for spatial aggregation are considered by using some types of nodes as IC, JC, RSE combination. Path travel times estimated by new aggregation methods are compared with PBM travel times by MAE, MAPE and statistical hypothesis tests. RESULTS : The results of minimum sample size and missing rate for 5 minutes aggregation interval are satisfied except for JC link path travel time in Seoul TG~Kuemho JC. Thus, it was additionally observed for minimum sample size satisfaction. In 15, 30 minutes and 1 hour aggregation intervals, all conditions are satisfied by the minimum sample size criteria. For accuracy test and statistical hypothesis test, it has been proved that RSE, Conzone, IC, JC links have equivalent errors and statistical characteristics. CONCLUSIONS : There are some errors between the PBM and the LBM methods that come from dropping vehicles by rest areas. Consequently, this survey result means each of links compositions are available for the estimation of path travel time when PBM vehicles are missed.

Determination of 226Ra in TENORM Sample Considering Radon Leakage Correction

  • Lim, Sooyeon;Syam, Nur Syamsi;Maeng, Seongjin;Lee, Sang Hoon
    • Journal of Radiation Protection and Research
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    • v.46 no.3
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    • pp.127-133
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    • 2021
  • Background: Phosphogypsum is material produced as a byproduct in fertilizer industry and is generally used for building materials. This material may contain enhanced radium-226 (226Ra) activity concentration compared to its natural concentration that may lead to indoor radon accumulation. Therefore, an accurate measurement method is proposed in this study to determine 226Ra activity concentration in phosphogypsum sample, considering the potential radon leakage from the sample container. Materials and Methods: The International Atomic Energy Agency (IAEA) phosphogypsum reference material was used as a sample in this study. High-purity germanium (HPGe) gamma spectrometry was used to measure the activity concentration of the 226Ra decay products, i.e., 214Bi and 214Pb. Marinelli beakers sealed with three different sealing methods were used as sample containers. Due to the potential leakage of radon from the Marinelli beaker (MB), correction to the activity concentration resulted in gamma spectrometry is needed. Therefore, the leaked fraction of radon escaped from the sample container was calculated and added to the gamma spectrometry measured values. Results and Discussion: Total activity concentration of 226Ra was determined by summing up the activity concentration from gamma spectrometry measurement and calculated concentration from radon leakage correction method. The results obtained from 214Bi peak were 723.4 ± 4.0 Bq·kg-1 in MB1 and 719.2 ± 3.5 Bq·kg-1 in MB2 that showed about 5% discrepancy compared to the certified activity. Besides, results obtained from 214Pb peak were 741.9 ± 3.6 Bq·kg-1 in MB1 and 740.1 ± 3.4 Bq·kg-1 in MB2 that showed about 2% difference compared to the certified activity measurement of 226Ra concentration activity. Conclusion: The results show that radon leakage correction was calculated with insignificant discrepancy to the certified values and provided improvement to the gamma spectrometry. Therefore, measuring 226Ra activity concentration in TENORM (technologically enhanced naturally occurring radioactive material) sample using radon leakage correction can be concluded as a convenient and accurate method that can be easily conducted with simple calculation.

Development of Variable Rolling Pressure Device for Bead-Shape Accuracy and Mechanical Property Enhancement in WAAM (Wire Arc Additive Manufacturing(WAAM)에서 적층 비드(Bead) 형상 정확도 및 기계적 특성 향상을 위한 가변 가압장치 개발)

  • Hwang, Ye-Han;Lee, Choon-Man;Kim, Dong-Hyeon
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.21 no.8
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    • pp.66-71
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    • 2022
  • Metal additive manufacturing (AM) has revolutionized several manufacturing industries. AM can generate large-scale metal components and produce complex geometries close to net-shapes. WAAM is an AM technology that has garnered considerable interest among industries owing to its economics and relatively high deposition rates. However, the heat accumulation in the weld bead during deposition triggers distortion and residual stress. To address these problems, various methods of interpass pressure rolling systems have been suggested in recent research. In addition, combining the rolling and WAAM processes can mitigate residual stresses. The constant-pressure rolling of the interlayer also affect the microstructure. The coarse microstructure of the as-deposited sample was altered to finer equiaxed grains via these methods. However, the bead-shape accuracy of the interlayer constant-pressure method does not consider the heat accumulation in each layer. Therefore, this study develops an interpass variable pressure rolling system that considers the heat accumulation of each layer. The interpass variable pressure rolling system comprises deposition, detection, pressure, and transport units. Finally, verification tests are performed on the interpass variable-pressure rolling system (at 500 kg) with the WAAM process, and the obtained results are discussed.

High School Students' Views about Some Topics of the Epistemology of Science (과학인식론의 일부 주제에 대한 고등학생들의 견해)

  • Woo, Jong-Ok;Soh, Won-Joo
    • Journal of The Korean Association For Science Education
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    • v.15 no.3
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    • pp.349-362
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    • 1995
  • As science programs emphasize an understanding of the nature of science, it is needed to assess students' views on a wide range of science-technology-society topics. The purpose of this study is to investigate the views of high school students about some selected topics of the epistemology of science. The selected topics include the meaning of science, scientific assumptions, values in science, conceptual inventions in science, scientific method, consensus making in science, and characteristics of the knowledge produced in science. Identified preconceptions in the study are as follows: Science was seen as improving the world(20%), and technology was defined as the application of science(35%). Almost half of the sample(49%) subscribed to a view consistent with a creationist posture and large group of students(46%) expressed a purely ontological view. Only minority of the students(5%) discounted the role played by private science values, but one half of the sample denied the fact that gender-related values can influence the knowledge that scientist construct(53%). Only a small potion of the sample(5%) held a view contrasting to contemporary epistemology of science, but the majority(67%) expressed a simplistic hierarchical relationship in which hypotheses become theories and theories become laws. One third of the students(33%) held a preconception that the scientific method composed of questioning, hypothesizing, collecting data, and concluding. Students did not appreciate the role of consensus making in science(33%). An out-dated epistemic perspective describes the progress of science as simply an accumulation of knowledge(4%). In general, it was concluded that most high school students did not hold efficient understanding on the nature of science. It can be said that no adequate and consistent instruction took place to provide students with an authentic view of the nature of science.

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