Browse > Article
http://dx.doi.org/10.5478/MSL.2018.9.4.110

Multi-class Analysis of Exposure Chemicals in Deciduous Teeth by Liquid Chromatography-Mass Spectrometry: Preliminary Studies on Sample Preparation Methods  

Lee, Yujin (Department of Chemistry, Hankuk University of Foreign Studies)
Seo, Eunji (Department of Chemistry, Hankuk University of Foreign Studies)
Park, Jun Young (Department of Chemistry, Hankuk University of Foreign Studies)
Bae, Kwang-Hak (Oral Health Science Research Center, Apple tree Dental Hospital)
Lee, Jaeick (Analytical Science and Technology Laboratory, Doping Control Center, Korea Institute of Science and Technology)
Cha, Sangwon (Department of Chemistry, Hankuk University of Foreign Studies)
Publication Information
Mass Spectrometry Letters / v.9, no.4, 2018 , pp. 110-114 More about this Journal
Abstract
Since accumulation of chemicals in deciduous teeth can occur from the second trimester of fetal development to shedding, a deciduous tooth has been considered as an attractive biomatrix for estimating individual chemical exposures recently. Therefore, detection of organic chemicals from teeth has received an increasing attention in exposomics research. Most previous studies on organic chemical analysis of teeth not only focused on a few targeted chemicals but also ignored potential contaminants from an enamel surface or a dental pulp. Recently, our group started developing a multi-class organic analysis method for deciduous teeth and tried to find a proper incubation condition of tooth materials. Our results showed that incubation with methanolic HCl provided the best performance among tested.
Keywords
exposomics; deciduous teeth; sample preparation; dentin; enamel;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Vrijheid, M. Thorax 2014, 69, 876.   DOI
2 Andra, S. S.; Austin, C.; Arora, M. Curr. Opin. Pediatr. 2016, 28, 221.   DOI
3 Hare, D.; Austin, C.; Doble, P.; Arora, M. J. Dent. 2011, 39, 397.   DOI
4 Lochner, F.; Appleton, J.; Keenan, F.; Cooke, M. Anal. Chim. Acta 1999, 401, 299.   DOI
5 Andra, S. S.; Austin, C.; Arora, M. Environ. Res. 2015, 142, 387.   DOI
6 Jan, J.; Vrbic, V. Caries Res. 2000, 34, 469.   DOI
7 Jan, J.; Vrecl, M.; Pogacnik, A.; Gaspersic, D. Arch. Oral Biol. 2001, 46, 1111.   DOI
8 Jan, J.; Vrecl, M.; Pogacnik, A.; Gaspersic, D.; Matjaz, Z. Environ. Toxicol. Pharmacol. 2006, 21, 103.   DOI
9 Jan, J.; Ursic, M.; Vrecl, M. Environ. Toxicol. Pharmacol. 2013, 36, 1040.   DOI
10 Kanjanawattana, S.; Mangkornkarn, C.; Wilairat, P.; Vongsavan, N. J. Endod. 2001, 27, 31.   DOI
11 Cattaneo, C.; Gigli, F.; Lodi, F.; Grandi, M. J. Forensic Odontostomatol. 2003, 21, 1.
12 Pellegrini, M.; Casa, A.; Marchei, E.; Pacifici, R.; Mayne, R.; Barbero, V.; Garcia-Algar, O.; Pichini, S. J. Pharm. Biomed. Anal. 2006, 40, 662.   DOI
13 Garcia-Algar, O.; Vall, O.; Segura, J.; Pascual, J. A.; Diaz, D.; Mutnoz, L.; Zuccaro, P.; Pacifici, R.; Pichini, S. J. AMA 2003, 290, 196.
14 Pascual, J. A.; Diaz, D.; Segura, J.; Garcia-Algar, O.; Vall, O.; Zuccaro, P.; Pacifici, R.; Pichini, S. Rapid Commun. Mass Spectrom. 2003, 17, 2853.   DOI
15 Marchei, E.; Joya, X.; Garcia-Algar, O.; Vall, O.; Pacifici, R.; Pichini, S. Rapid Commun. Mass Spectrom. 2008, 22, 2609.   DOI
16 Fos, P.; Forner, L.; Llena, C.; Anadon, A. Int. Dentistry SA 2011, 13, 50.
17 Andra, S. S.; Austin, C.; Wright, R. O.; Arora, M. Environ. Int. 2015, 83, 137.   DOI
18 Schussl, Y.; Pelz, K.; Kempf, J.; Otten, J. E. Clin. Oral Investig. 2014, 18, 35.   DOI
19 Camann, D. E.; Schultz, S. T.; Yau, A. Y.; Heilbrun, L. P.; Zuniga, M. M.; Palmer, R. F.; Miller, C. S. J. Expo. Environ. Epidemiol. 2013, 23, 190.   DOI
20 Palmer, R. F.; Heilbrun, L.; Camman, D.; Yau, A.; Schultz, S.; Elisco, V.; Tapia, B.; Garza, N.; Miller, C. J. Environ. Public Health 2015, 2015, 862414.
21 Frerderiksen, H.; Jorgensen, N.; Andersson, A. M. J. Anal. Toxicol. 2010, 34, 400.   DOI
22 Jeong, E. S.; Kim, S. H.; Cha, E. J.; Lee, K. M.; Kim, H. J.; Lee, S. W.; Kwon, O. S.; Lee, J. Rapid Commun. Mass Spectrom. 2015, 29, 367.   DOI
23 Rochester, J. R.; Bolden, A. L. Environ. Health Perspect. 2015, 123, 643.   DOI
24 Han, Y.; Jia, X.; Liu, X.; Duan, T.; Chen, H. Chromatographia, 2010, 72, 351.   DOI