• 자동차안전학회지
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• 제9권1호
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• pp.19-24
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• 2017

This paper present a performance evaluation scenarios to assess the safety performance of autonomous emergency braking (AEB) system for cyclist collision. To guarantee the safety performance of AEB for cyclist, AEB system should be tested in various scenarios which can be occurred in real driving condition. For this, real-traffic car-to-cyclist collision data are analyzed to classify the real traffic collision scenarios. Using this information, typical car-to-cyclist collision scenarios are selected. Also, in order to develop the detail features of these collision scenarios, several accident cases related with these scenarios are explained. Based on these information, test scenarios which can describe the car-to-cyclist collisions occurred in Korea are proposed. For practicality and feasibility of the test scenarios, proposed scenarios should be designed to assess the safety performance of AEB system effectively. For this, some test scenarios are combined or removed based on the consideration about the effectiveness of each scenario to the assessment of the performance of AEB system. To confirm that the proposed test scenarios are realistic and physically meaningful, simulation is conducted using simple AEB system in proposed test scenarios.

• Biomolecules & Therapeutics
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• 제3권3호
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• pp.242-244
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• 1995

In vitro cell culture system has been proposed as a promising alternative model to in vivo skin irritation test. These studies were performed to screen the cytotoxicity effects of surfactants using normal human skin fibroblasts. Cell membrane integrity assessed by the leakage of lactate dehydrogenase (LDH) and mitochondrial integrity by MTT [3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromides reduction test were affected in a dose dependent manner. The irritation potential of surfactants to human skin patch test, and the changes of capillary permeability by rabbit intradermal safety test were assessed as in vivo methods. Our results suggest that LDH leakage assay and MTT reduction test using cultured human fibroblasts could be predictive for the irritancy of various surfactants in human, and LDH assay is superior correlated with in vivo test (r=0.886) to MTT test with in vivotest (r=0.757).

• 융합정보논문지
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• 제10권9호
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• pp.147-153
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• 2020

드론 산업이 최근 4차 산업 혁명을 주도하는 분야로 발표되면서 드론 시장을 창출하기 위해 많은 투자와 연구가 이루어지고 있다. 그러나 드론 시험비행에 대한 수요가 급격히 증가함에 따라 고흥 항공센터만으로는 시험비행 요구를 충족시키기가 어려우며, 드론과 같이 신규 개발하였거나 기존 형상을 개조한 비행체가 비행시험장이 아닌 곳에서 시험비행을 수행할 시 예측할 수 없는 비행성능이나 조종 미숙으로 인한 잠재적 사고 위험성을 가지고 있다. 따라서 유인 및 무인 항공기의 안전 검증을 위해 충분한 시험비행 공간의 확보가 필수적이다. 따라서 본 연구는 국내 비행시험장의 상태와 ICAO DOC 9184-AN / 902 Part 1을 분석 하여, 종합적인 비행 테스트 인프라를 구축하기 위한 비행 테스트 사이트 예비 평가 방법과 인프라 사이트 평가 방법을 제시하였다.

• 한국수소및신에너지학회논문집
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• 제23권6호
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• pp.612-618
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• 2012

In this paper, in order to prevent electric shock of high voltage system of HFCV after crash test, insulation performance measurement methods were studied. Under conditions of in-use, insulation performance tests can be divided into measurement method using the vehicle's own RESS as DC voltage source and measurement method using DC voltage from off-vehicle sources. However, these tests can not be applied after a post-crash because parts of high voltage system cover should be removed, and insulation performance can be influenced during these tests. Therefore, we proposed post-crash insulation performance test methods for preventing electric shock through problem analysis of previous post-crash insulation performance tests. Also, test equipment which can measure voltage absence and total energy was developed. We verified performance of the equipment through experiments with vehicle test.

• Toxicological Research
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• 제3권1호
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• pp.15-26
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• 1987

The mutagenicity of pranoprofen, a new antiinflammatory agent primarily used in Japan, was evaluated by employing several different methods such as the Ames test, micronucleus test, and the sister chromatid exchange test. For the Ames test, various doses of pranoprofen (5 and 1 mg, 100, 10, and 1 ${\mu}$g per plate) were applied, with or without the mammalian liver S-9 fraction, to the S. typhimurium LT2. For the micronucleus test, 24 hours after administering the various doses of pranoprofen (200, 100, and 50 mg/kg) to male mice by aral intubation, the femura of each group were isolated and the bone marrow samples were prepared. The micronucleated red cells and the ratio of the polychromatic versus the normochroomatic cells were counted. For the sister chromatid exchange test, the maximal non-cytotoxic concentrations (10 to 0.1 mM pranoprofen) were applied to the culture media of the Chinese Hamster Ovary (CHO) cells for 24 hrs. The numbers of revertant colonies did not increase with the increasing doses of pranoprofen when teseted with various strains of S. typhimurium. In the micronucleus test employing mice, the pranoprofen was identkfied to be a non-clastogen and a non-spindle poison. In the sister chromatid exchange test employing the cultured CHO cells, the pranoprofen did not increase the incidences of chromosomal abnormality. Based on these results, pranoprofen was found to have no mutagenic activity.

• 약학회지
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• 제57권3호
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• pp.205-212
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• 2013

Dissolution test has been performed to control drug quality and to predict in vivo drug release profile of solid dosage forms, so there's a drift towards setting dissolution test instead of disintegration test. However, some solid dosage forms in Korea Pharmaceutical Codex (KPC) are not established the dissolution test yet, so these monographs are necessary to set the specification of dissolution test. In this study, we developed the specification and test method of dissolution test for itopride hydrochloride tablets and tiropramide hydrochloride tablets which are not established the dissolution test yet. According to the "Manual for Guideline Application for Validation of Analytical Procedures" and "Guidelines on Specification of Dissolution test for Oral dosage form" of Korean Pharmacopoeia (KP), we validated and established each development method. Based on the preliminary dissolution profile, we set the dissolution condition(paddle apparatus, pH 1.2 media, 50 rpm). For this condition, we performed the main dissolution test to determine the specification (45 min, 85%). Finally, we validated each analytical method by specificity, linearity, accuracy and precision. These developed methods will be included the next supplement of KPC and also contributed to the quality control of medicines.

• 항공우주기술
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• 제12권1호
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• pp.182-188
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• 2013

본 논문에서는 비행안전통제실, 비행정보전시시스템 및 비행안전통제원의 임무 및 훈련을 순차적으로 기술하고 KSLV-I 3차 비행중 실시간으로 처리된 데이터 및 분석 결과를 제시하였다. 3차 비행시험의 비행안전통제실 운용에서, KSLV-I 비행 상황 감시가 정상적으로 이루어졌으며 순간낙하점 계산을 포함한 비행안전 알고리듬 계산도 정상적으로 수행되었다.

• 지역사회간호학회지
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• 제11권2호
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• pp.566-576
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• 2000

This study was carried out to examine the effects of school safety education on the safety behavior among elementary school students. Sixty-two 4th grade students were sampled from an elementary school in Pohang city and divided into one experimental group and one control group. The safety education has been provided to the experimental group for 4 weeks The data were collected before, just after, and 8 weeks after the education. In the pre-test, the general characteristics and safety behavior between two groups were measured. The experimental group was given school safety education twice a week for 4weeks. They also filled out the self behavior check list. In the post-test and follow up-test safety behavior was collected. The data analysis was done using $X^2$-test. t-test. Repeated measures ANOVA, analysis of simple main effect and time contrast methods, they were processed with an SPSS Win 9.0/pc. The results of this study are summarized as follows: 1) There were no differences between experimental group and control group on the general characteristics and safety behavior in the pre-test. 2) The hypothesis: 'The experimental group which was given school safety education will show higher scores on safety behavior than the control group which was not given this was supported(F=6.43 p=0.01). 3) The subhypothesis 1 : 'The scores on the indoor safety behavior of the experimental group which was given school safety education will show higher than those of the control group which were given this was supported(F=3.59 p=0.03). 4) The subhypothesis 2 : 'The scores on the outdoor safety behavior of the experimental group which was given, school safety education will show higher than those of the control group which was not given this was supported(F=5.70 p =0.00). In consequence, the experimental group which was given school safety education scored higher on safety behavior than the control group. Therefore, school safety education should continue to encourage safety behavior among elementary school students.

• 한국안전학회지
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• 제17권3호
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• pp.102-106
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• 2002

The Act on Safety Management of Social Assets was established on 1995 and revised on 1999 to relieve maintenance cost of managing offices. The provision for load bearing test before opening was deleted and the number of load bearing test after opening was reduced in the Revised Act on 1999. The effect of revision is the main concern in this study. 176 technical reports on load bearing test of long span bridges are analyzed. The results show that various structural defects are inherent in recent bridges constructed since 1995. So the preservation of provisions deleted in original act is needed up to now.

• KIEAE Journal
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• 제7권4호
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• pp.119-126
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• 2007

In this study, we processed two procedures of application test of filler for fire-resistance utility that are new application methods of aerated concrete and properties test of aerated concrete according to mixing ratio because we investigated the better use of aerated concrete as filler for fireproof safety and we proposed basic data about standardization of mixing of aerated concrete. We measured flow and volume change of aerated concrete. And if its volume doesn't change, we added measuring unit weight and compressive strength. To test application of aerated concrete as filler for fireproof safety, we filled up aerated concrete to fireproof safety according to suitable mixing ratio. Then we measured maximum temperature of inner part of fireproof safety in accordance with the standard test of fireproof. According to the results, aerated concrete as filler for fireproof safety could be possibly used. So when we make aerated concrete, we should consider using an adding agent as well as a foaming agent.