• 제목/요약/키워드: Safety standard

검색결과 4,276건 처리시간 0.031초

A Collaborative Study to Establish the Second Korean National Reference Standard for Snake Venom

  • Han, Kiwon;Jung, Kikyung;Oh, Hokyung;Song, Hojin;Park, Sangmi;Kim, Ji-Hye;Min, Garam;Lee, Byung-Hwa;Nam, Hyun-sik;Kim, Yang Jin;Ato, Manabu;Jeong, Jayoung;Ahn, Chiyoung
    • Toxicological Research
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    • 제34권3호
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    • pp.191-197
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    • 2018
  • In 2015, a candidate for the second national reference standard (NRS) of Gloydius snake venom was produced to replace the first NRS of Gloydius snake venom. In the present study, the potencies of the candidate were determined by a collaborative study, and the qualification of the candidate was estimated. The potencies of the candidate were determined by measuring the murine lethal titers and lapine hemorrhagic titers of venom against the regional working reference standard (RWRS) for antivenom using the methods described in the previous report for the first NRS of Gloydius snake venom. Three Korean facilities contributed data from a total of 30 independent assays. Subsequently, two foreign national control research laboratories contributed to this collaborative study. The results were calculated using the Reed-Muench method for lethality and determined using a mixed-effects model for hemorrhage. The general common potencies of the lethal and hemorrhagic titers were obtained from the results of the 30 tests performed at three Korean facilities. The results are expressed in micrograms for 1 test dose (TD) with a 95% confidence interval as follows: a lethal titer of $90.13{\mu}g/TD$ (95% confidence interval = $87.39{\sim}92.86{\mu}g$) and a hemorrhagic titer of $10.80{\mu}g/TD$ (95% confidence interval = $10.46{\sim}11.14{\mu}g$). In addition, the candidate preparation showed good quality evaluation according to the results of the quality estimation of the candidate and is judged to be suitable to serve as the Korean NRS for snake venom. In conclusion, the second NRS of Gloydius snake venom was established in this study and will be used for national quality control, including a national lot release test of Korean antivenom products.

국제표준에 따른 기업의 대응전략 (Strategy of Korean Company for International Standardization)

  • 최성운;백봉기
    • 대한안전경영과학회지
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    • 제6권1호
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    • pp.247-256
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    • 2004
  • Recently, International Standardization is an important issue in competitive world market because of integration of standard, liberalization of international trade and globalization. Consequently, Korean companies need a strategy about corresponding to market circumstance and global standard. In this study, we examine Intellectual Property, Patent and Antitrust Law which are related to standardization. This study suggests company strategy and system integration model to dispose the global standard.

물류용어의 일관성 제고를 위한 원칙과 표준화에 관한 연구 - KS 표준을 중심으로 (A Study on Principles and Standardization of Logistics Terminologies in Korean Standard to Improve Consistency)

  • 김국;유영관
    • 대한안전경영과학회지
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    • 제11권4호
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    • pp.177-191
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    • 2009
  • In this study, we suggest a standardization of the logistics terminologies in Korean Standard to improve its consistency. To support this work, some principles for terminology selection and corrections are studied based on the guideline in international standard. The revised terminologies are summarized in Appendix for 20 logistics-related Korean Standards.

표준형 및 속동형 스프링클러헤드의 반응시간지수와 소화성능 (Response Time Index and Suppression Capability of Standard and Quick Response Sprinkler Head)

  • 정길순;이병곤
    • 한국안전학회지
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    • 제13권4호
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    • pp.59-70
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    • 1998
  • In this study, response time index(RTI) of standard and quick response type sprinkler head are measured and compared through ramp and plunge test in heated wind tunnel. Also discharge rate and water distribution, actual delivered density(ADD), fire test with wood cribs are performed to compare the fire suppression capability and the operation time and temperature between standard and quick response type sprinkler head.

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우연, 이상원인의 유형에 따른 $C_{PK}$, $P_{PK}$의 이해와 적용방안 (Understanding and Use of $C_{PK}$ and $P_{PK}$ According to the Pattern of Common and Assignable Causes)

  • 최성운
    • 대한안전경영과학회:학술대회논문집
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    • 대한안전경영과학회 2009년도 추계학술대회
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    • pp.549-555
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    • 2009
  • The research proposes two calculation methods for estimating the overall, within and between standard deviation of population. These standard deviations can be used to evaluate the process capability and performance indexes. The guidelines for using $C_{PK}$ and $P_{PK}$ according to the pattern of common and assignable causes are presented.

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CFD 툴을 활용한 패키지형 수소충전시스템의 안전성 향상 연구 (A Study on the Safety Improvement by CFD Analysis for Packaged Type Hydrogen Refueling System)

  • 황순일;강승규;허윤실
    • 한국수소및신에너지학회논문집
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    • 제30권3호
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    • pp.243-250
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    • 2019
  • In this study, to ensure the safety of the packaged hydrogen refueling system, the improvement plan was derived by using 3-dimensional CFD program (FLACS). We also confirmed the effectiveness of risk reduction and the suitability of safety standard. By ventilation performance evaluation according to the position of the vent, it demonstrated that the vent should be installed at the ceiling to safely ventilate without stagnation of the leaked gas. In case of ventilation system according to KGS standard, risk situation could be resolved after about 5 minutes in the worst leaked condition. The result showed that jet fire and explosion inside the packaged system could affect the surrounding facilities. This proves that the standard for installing flame detectors, emergency shut down system and protection wall is appropriate.

자동차 부품업체의 업무 효율성 향상을 위한 표준관리시스템 구축에 관한 연구 (A Study on the Development Of Standard Management System for the Work Efficiency Improvement of the Auto Part Supplier)

  • 이희남;박제원
    • 대한안전경영과학회지
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    • 제12권4호
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    • pp.223-228
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    • 2010
  • Recently, the various information according to the company management is originated in the change of the rapid company environment. And the necessity of the administration,that is systematic and efficient toward the various document of a form, is gradually increased. At the same time, the efficient management ability of the various standard document obtained the specialized quality authentication system including the ISO/TS16949, ISO14001, quality 5 star, and etc., it maintains occupies the very important part as to the company management. This research suggests the standard business process of the auto part supplier for the efficient management of the standard document. In addition, by building and managing the standard management system will be able to expect the more efficient document management and the product reliability insurance.

세척공정의 트리클로로에틸렌 TWA 및 STEL 평가 사례 (TCE Exposure Assessment of Cleaning Workers)

  • 김현수
    • 한국산업보건학회지
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    • 제33권1호
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    • pp.3-5
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    • 2023
  • Objective: This study introduces exposure concentrations of time-weighted average standard (TWA) evaluation and short-time exposure standard (STEL) evaluation for trichloroethylene in the cleaning process. Methods: Trichloroethylene measurement was conducted according to the KOSHA Guide (A-24-2019) method. It was carried out twice. Results: As a result of the first measurement, TWA concentration exceeded 4 times the exposure standard and STEL concentration exceeded 16 times, but the inaccuracy and breakthrough of the collection time could not be considered, so the second measurement was conducted. The second measurement result was lower than the first measurement result, but exceeded the exposure standards (TWA, STEL). Conclusions: We were able to confirm that the exposure level of workers in the cleaning process using trichloroethylene exceeded the exposure standard. And it is also considered necessary to grasp the approximate concentration using a detector tube in the preliminary survey.

국제 규격 접지시스템의 국내 적용을 위한 시뮬레이션 기반의 안전도 평가 방안 (Method for Safety-Decision to Apply International Standard Grounding Systems to Domestic Power System by Computer Simulation)

  • 이순;김정훈;박정욱
    • 전기학회논문지
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    • 제57권3호
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    • pp.344-353
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    • 2008
  • To apply the appropriate new grounding system to domestic power system, safety has to be guaranteed under the given circumstances. It is not possible to decide the safety of grounding systems by the experimental test because safety experiments directly relate to the human life and the installed electric machines. Therefore, the computer simulation program to decide the safety of grounding systems based on the IEC standard systems, has to be developed. This paper proposes the computer simulation based method to decide the safety of grounding system with the concepts of touch voltage, step voltage, human resistivity, and applied electric current according to the several conditions of human body located in the corresponding grounding systems. The proposed method is implemented by Matlab/Simulink and Visual C++ programming tools for its visualization.