• Safety and Health at Work
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• 제4권4호
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• pp.177-186
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• 2013

The use of nanoparticles (NPs) in industry is increasing, bringing with it a number of adverse health effects on workers. Like other chemical carcinogens, NPs can cause cancer via oxidative DNA damage. Of all the molecules vulnerable to oxidative modification by NPs, DNA has received the greatest attention, and biomarkers of exposure and effect are nearing validation. This review concentrates on studies published between 2000 and 2012 that attempted to detect oxidative DNA damage in humans, laboratory animals, and cell lines. It is important to review these studies to improve the current understanding of the oxidative DNA damage caused by NP exposure in the workplace. In addition to examining studies on oxidative damage, this review briefly describes NPs, giving some examples of their adverse effects, and reviews occupational exposure assessments and approaches to minimizing exposure (e.g., personal protective equipment and engineering controls such as fume hoods). Current recommendations to minimize exposure are largely based on common sense, analogy to ultrafine material toxicity, and general health and safety recommendations.

• Safety and Health at Work
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• 제8권2호
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• pp.156-161
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• 2017

Background: Occupational Health and Safety Management Systems are becoming more widespread in organizations. Consequently, their effectiveness has become a core topic for researchers. This paper evaluates the performance of the Occupational Health and Safety Assessment Series 18001 specification in certified companies in Iran. Methods: The evaluation is based on a comparison of specific criteria and indictors related to occupational health and safety management practices in three certified and three noncertified companies. Results: Findings indicate that the performance of certified companies with respect to occupational health and safety management practices is significantly better than that of noncertified companies. Conclusion: Occupational Health and Safety Assessment Series 18001-certified companies have a better level of occupational health and safety; this supports the argument that Occupational Health and Safety Management Systems play an important strategic role in health and safety in the workplace.

• 한국산업보건학회지
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• 제27권1호
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• pp.1-12
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• 2017

Objectives: The major objectives of this study are to review the requirements for the advancement of occupational safety and health administrative organization and to propose measures to establish an Occupational Safety and Health Executive. Methods: The problems of occupational safety and health administrative organization in korea were examined empirically and cases of occupational safety and health administrative organizations in developed countries were investigated (United Kingdom, United States, Germany, and Japan). A plan for establishing an Occupational Safety and Health Executive was proposed over the short and medium term. Results: An occupational safety and health administration is characterized by a professional and technical nature, and even more so in modern society. Therefore the greatest value required by an occupational safety and health administrative organization is expertise. In addition, administrative values it requires include efficiency, specificity, independence, and activity. The Korean occupational safety and health administrative organization has a number of problems in terms of these values. The most appropriate way to realize these values is to establish an Occupational Safety and Health Executive. It is desirable to establish such an Occupational Safety and Health Executive in a phased manner taking into consideration its relationship with Korea Occupational Safety and Health Agency(KOSHA), including KOSHA's functional adjustment Conclusions: In order to solve the deep-seated problems in occupational safety and health administrative organization and to advance occupational safety and health administration in Korea, it is necessary to establish an Occupational Safety and Health Executive as a foundation for achieving an advanced industrial safety and health administration.

• 한국컴퓨터정보학회논문지
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• 제24권8호
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• pp.151-158
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• 2019

In this paper, we conducted a study to understand the impacts of safety behavior, safety and health delivery and communication, which should be managed for the establishments' safety and health control on occupational safety and health policy satisfaction to utilize that as a material for preparing policy support and preventive measures. For this purpose, we conducted a statistic analysis with 2,970 establishments, utilizing the material, "2015 Occupational Safety and Health Company Survey". As a result, in the manufacturing industry, it turned out in the establishments with more than 300 workers, safety behavior, safety and health delivery and communication of the cooperative firm of the prime contractor were high. In addition, it turned out that safety behaviors had the biggest impact on occupational safety and health policy satisfaction in the manufacturing industry and safety and health delivery and communication had the biggest impact on occupational safety and health policy satisfaction in the construction industry and other industries. As for the relationship between companies, it turned out that safety behaviors had the biggest impact on that between the parent company and a cooperative firm of a prime contractor while safety and health delivery and communication on that between the prime contractor and the subcontractor. Through the results of this study, it is necessary to build up safety and health behavior and safety and health delivery and communication systems for the characteristics of the company, and it is expected that the effect of the safety and health control will increase when policy support is made accordingly.

• Environmental Analysis Health and Toxicology
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• 제22권1호
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• pp.91-101
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• 2007

The new chemicals are developed and circulated without the verified toxicity data. So, the accidents and occupational diseases, such as explosion, fire, suffocation about deadly poisons etc. are frequently to workers. Classifications of chemicals suited with guideline and an offer of correct chemical information data are the molt important thing for the establishment of suitable chemical management system. The GHS (Globally Harmonized System of classification and labeling of chemicals) is based with the chemical classifications and unification plan. The warning symbol and phrases are established for improvements of chemical information data system. According to these unified and improved systematic form of data, and the chemical information data, the workplaces will be presented many chemical safety and risk data correctly. In this paper, we will present constructions and accomplishment contents-based chemical management of workplace through development of chemical information data and the nice using for new chemical investigation and risk assessment of chemicals in workplaces.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 추계학술대회
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• pp.125-125
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• 2003

Respiratory effects in full time welders include bronchitis, airway irritation, lung function changes, and lung fibrosis. Welder's pneumoconiosis has been generally determined to be benign and not associated with respiratory symptoms based on the absence of pulmonary function abnormalities in welders with marked radiographic abnormalities.(omitted)

• Safety and Health at Work
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• 제2권1호
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• pp.17-25
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• 2011

Objectives: In this study, the in vitro mammalian chromosomal aberration (CA) assay was conducted to gain additional information concerning the hazards associated with the use of cyclopentane and ammonium nitrate. While these two chemicals had already been tested by many methods, they had not been studied in the CA test. Methods: The assay was performed using the ovarian infantile cell (CHO-K1 cell), by the direct method (-S9) and by the metabolic activated method (+S9 mix). Results: Using the direct method, the 7 dosages in a 48 hour treatment group did not show that the frequency of CA is proportion to the dosage addition. The frequency of CA is not proportion to the dosage addition for a 6 hour treatment using the metabolic activated method. Conclusion: From these findings, it was decided that the 2 chemicals do not induce chromosomal aberrations under the tested conditions.

• Safety and Health at Work
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• 제3권3호
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• pp.224-234
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• 2012

Objectives: This study was conducted in order to obtain information concerning the health hazards that may result from a 13 week inhalation exposure of n-pentane in Sprague-Dawley rats. Methods: This study was conducted in accordance with the Organization for Economic Co-operation and Development (OECD) guidelines for the testing of chemicals No. 413 'Subchronic inhalation toxicity: 90-day study (as revised in 2009)'. The rats were divided into 4 groups (10 male and 10 female rats in each group), and were exposed to 0, 340, 1,530, and 6,885 ppm n-pentane in each exposure chamber for 6 hour/day, 5 days/week, for 13 weeks. All of the rats were sacrificed at the end of the treatment period. During the test period, clinical signs, mortality, body weights, food consumption, ophthalmoscopy, locomotion activity, urinalysis, hematology, serum biochemistry, gross findings, organ weights, and histopathology were assessed. Results: During the period of testing, there were no treatment related effects on the clinical findings, body weight, food consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, gross findings, relative organ weight, and histopathological findings. Conclusion: The no-observable-adverse-effect level (NOAEL) of n-pentane is evaluated as being more than 6,885 ppm (20.3 mg/L) in both male and female rats. n-pentane was not a classified specific target organ toxicity in the globally harmonized classification system (GHS).

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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• pp.151-151
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• 2001

According to the epidemiological studies in chromium workers, hexavalent chromium is associated with the risk of lung cancer. Reactive oxygen species produced by hexavalent chromium exposure may play an important role in the carcinogenesis process. We measured one kind of oxidative DNA damages, 8-hydroxydeoxyguanosine (8-OHdG) and its repair activities as an indicators of cellular oxidative stress in rat lungs by the repeated inhalation exposure to sodium chromate.(omitted)

• 대한안전경영과학회지
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• 제15권2호
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• pp.21-30
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• 2013

OSHMS(Occupational Safety and Health Management System) is able to define as a typical convergence of all kinds of activities and elements that support maintaining safety at workplace and protecting employee's health. In particular, fundamental function of OSHMS is preventing diverse hazards at workplace through high level of regulation compliance. Furthermore, insuring safety in workplace, protecting employee's health and increasing effectiveness in manufacture are OSHMS's additional functions. Based on the division of manufacture in 2009 Survey on Current Status of Occupational Health & Safety data, the study analyses certain relation between OSHMS and level of regulation compliance. The main finding is that most activities and elements which formed by OSHMS are being affected by regulation clauses.