• Title/Summary/Keyword: Safe Behavior

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The Prophylactic and Therapeutic Effects of Saffron Extract and Crocin on Ethanol Withdrawal Syndrome in Mice

  • Shoja, Maryam;Mehri, Soghra;Amin, Bahareh;Askari, Vahid Reza;Hosseinzadeh, Hossein
    • Journal of Pharmacopuncture
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    • v.21 no.4
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    • pp.277-283
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    • 2018
  • Objectives: Ethanol withdrawal following its chronic use is a serious outcome and challenging to treatment. The chronic use of ethanol induces a progressive neuroplasticity in different reigns of brain. In this study we evaluated the effects of aqueous extract of Crocus sativus L. (saffron) and its active compound, crocin, on the withdrawal behavior induced after repeated administration of ethanol, in two regimens of prophylactic (administration of drugs concomitant with the induction of dependence) and treatment (administration of drugs during the period of ethanol withdrawal) in mice which received ethanol. Methods: Ethanol dependence was induced by oral administration of 10% v/v ethanol (2 g/kg) for 7 days. The aqueous extracts of saffron (40, 80 and 160) and crocin (10, 20 and 40 mg/kg) were administered to mice in two regimens of prophylactic (along with ethanol) and treatment (during withdrawal period). Diazepam (1 mg/kg) was used as a positive control. Six hours after discontinuation of the ethanol, seizure was evaluated by the sub-convulsive dose of pentyleneltetrazole (PTZ) (30 mg/kg). The open field test and Rota rod test were used for evaluation of locomotor activity and motor incoordination, respectively. Results: Both extracts and crocin increased the number of crossed lined in the open field test. PTZ kindling seizure was inhibited in animals received extract (80 and 160 mg/kg) in both regimens. Motor incoordination was only improved following administration of crocin. Conclusion: The aqueous extract of saffron and crocin can be considered as safe agents and reliable alternative to diazepam in management of ethanol withdrawal syndrome.

『Rivers of Joseon』 Analysis of the Disaster Management System During the Great Flood of the Eulchuk Year (조선시대와 현대의 재난관리계층 비교분석 : 『조선의 하천』 을축년 대홍수와 괴산댐 월류를 중심으로)

  • Kwon, Seol A;Na, Jong Il;Byun, Sung-Soo
    • The Journal of the Korea Contents Association
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    • v.19 no.1
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    • pp.472-483
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    • 2019
  • Why can't we be free from diverse crises threatening our lives in a high-tech future society? Disasters interrupt habitual and institutionalized patterns of behavior and bring about a kind of social shock to make people follow social and individual changes. An interesting fact revealed in the study finding is that the role of disaster management control tower was proper during the Great Flood ofthe Eulchuk Year(1925) and the unified disaster management system facilitated smooth cooperation with relevant authorities. Also, motivating disaster management organizations positively influenced organizational commitment. This implies that if we constantly ask to improve current institutions by introspecting and learning, based on historical records, we may be able to find insights for a safe society of the future.

Static and dynamic characterization of a flexible scaled joined-wing flight test demonstrator

  • Carregado, Jose;Warwick, Stephen;Richards, Jenner;Engelsen, Frode;Suleman, Afzal
    • Advances in aircraft and spacecraft science
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    • v.6 no.2
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    • pp.117-144
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    • 2019
  • High Altitude and Long Endurance (HALE) aircraft are capable of providing intelligence, surveillance and reconnaissance (ISR) capabilities over vast geographic areas when equipped with advanced sensor packages. As their use becomes more widespread, the demand for additional range, endurance and payload capability will increase and designers are exploring non-conventional configurations to meet the increasing demands. One such configuration is the joined-wing concept. A joined-wing aircraft is one that typically connects a front and aft wings in a diamond shaped planform. One such example is the Boeing SensorCraft configuration. While the joined-wing configuration offers potential benefits regarding aerodynamic efficiency, structural weight, and sensing capabilities, structural design requires careful consideration of elastic buckling resulting from the aft wing supporting, in compression, part of the forward wing structural loading. It has been shown already that this is a nonlinear phenomenon, involving geometric nonlinearities and follower forces that tend to flatten the entire configuration, leading to structural overload due to the loss of the aft wing's ability to support the forward wing load. Severe gusts are likely to be the critical design condition, with flight control system interaction in the form of Gust Load Alleviation (GLA) playing a key role in minimizing the structural loads. The University of Victoria Center for Aerospace Research (UVic-CfAR) has built a 3-meter span scaled and flexible wing UAV based on the Boeing SensorCraft design. The goal is to validate the nonlinear structural behavior in flight. The main objective of this research work is to perform Ground Vibration Tests (GVT) to characterize the dynamic properties of the scaled flight vehicle. Results from the experimental tests are used to characterize the modal dynamics of the aircraft, and to validate the numerical models. The GVT results are an important step towards a safe flight test program.

An experimental study of electrocution-decreasing methods for Oriental Storks (Ciconia boyciana) in captivity (재도입 황새(Ciconia boyciana)의 감전사 저감을 위한 사례연구)

  • Ha, Dong-Soo;Nam, Hyung-Kyu;Yoon, Jongmin
    • Korean Journal of Ornithology
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    • v.25 no.2
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    • pp.112-116
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    • 2018
  • Electrocution is one of the key components affecting the mortality of birds. Various electrocution-decreasing methods refer to two directions: safe perching with insulation versus perching restriction. In Yesan County, we have reintroduced 30 oriental storks (Ciconia boyciana) since 2015. Two female storks died due to electrocution while perching in a utility pole in 2016. To reduce such electrocution mortality in storks, a branch of Korea Electric Power Corporation partly installed insulators in 630 utility poles located in the major habitats of Yesan in 2016-2017. Simultaneously, we conducted an experiment to reduce the perching events using 8 captive storks and the two types of common utility poles along with/without the installation of bird-spikes and/or wires in Mar-Jun of 2017. Our results indicated the installation of additional wires alone exhibited a lack of reduction in perching, while those of bird-spikes or both significantly decreased their perching frequencies. Therefore, the present study highlights the installation of bird spikes on top of utility poles may elicit a better effect so that storks avoid perching in utility poles, presumably resulting in lowering potential electrocution in the wild.

Determination of Weaving Section at Highway Collector-Distrivutor (집산로가 설치된 고속도로 위빙구간 유출입부 설계기준 제시)

  • Oh, Jaechul;Kim, Yoon Mi;Lee, Hyung Mu;Ha, Tae Jun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.38 no.6
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    • pp.879-885
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    • 2018
  • The highway weaving section is a point where there is a conflict caused by entry and exit vehicles. In order to minimize the impact on the main line, an accumulation line should be installed. The design speed of the collecting part is 50 km/h, but the actual driver does not have proper deceleration according to the design speed. In this study, considering the driving behaviors, the design specification, and the driver 's viewing angle, the appropriate separation distance for safe entry and exit of collecting, connecting, and collecting roads was examined. As a result of the analysis, it is found that a distance of 60m is required from the point where the merging starts. The results of this study are expected to contribute to the improvement of driver safety due to the conflict between entry and exit vehicles when applied to the weaving section where collecting roads are installed.

The Friction and Wear Characteristics of the Seat Recliner Parts Based on Lubricant Characteristics (윤활제 특성에 따른 시트 리클라이너 부품의 마찰 및 마모 특성)

  • Hong, Seok-June;Lee, Kwang-Hee;Lim, Hyun-Woo;Kim, Jae-Woong;Lee, Chul-Hee
    • Tribology and Lubricants
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    • v.35 no.3
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    • pp.183-189
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    • 2019
  • The driver seat of an automobile is in direct contact with the driver and provides the driver with a safe and comfortable ride. The seat consists of a frame, a rail, and many recliners. In recent years, strength and operating force measurement testing of the recliner have become vital for designing car seats. However, performance evaluation requires expensive testing equipment, numerous seat products, and considerable time. Therefore, the trend is to reduce experimentation through interpretation. This study examines the lubrication of solid lubricant for automotive seat recliners and confirms the friction and wear performance. In this study, the lubrication behavior of solid lubricants for car seat recliners is investigated to ascertain the friction and wear performance and to provide accurate values for the strength analysis. The friction material consists of a pin and a plate made from steel, which is widely used in recliners. The friction and wear under lubrication conditions are measured by a reciprocating friction wear tester. The friction coefficient is obtained according to the load and speed. Based on the obtained results, it is possible to achieve a reduction in the error of the test value and the analysis by providing the friction coefficient and wear of the lubricant. The results can be applied to the analysis of automobile seat design.

Evaluation of Structural Safety of Linear Actuator for Flap Control of Aircraft (항공기 플랩 제어를 위한 선형 구동기의 구조 안전성 평가)

  • Kim, Dong-Hyeop;Kim, Sang-Woo
    • Journal of Aerospace System Engineering
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    • v.13 no.4
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    • pp.66-73
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    • 2019
  • The objective of this study was to evaluate the structural safety of the basic design for the linear actuator for the flap control of aircrafts. The kinetic behavior of the linear actuator was determined using the multi-body dynamics (MBD) analysis, and the contact force was calculated to be used as input data for the structural analysis based on the finite element analysis. In the structural analysis, the thermal and static behaviors of the linear actuator satisfying the designed velocity were examined, and the structural safety of the linear actuator evaluated. Moreover, the dynamic behaviors of the key components of the linear actuator were investigated by the modal analysis. The actuation rod linearly moved with about 5 mm/s when the motor operated at 225 rpm and the maximum contact force of 32.83 N occurred between two driving gears. Meanwhile, the structural analysis revealed that the maximum thermal and static stresses were 1.57% and 78% of the yield strength of steel, respectively, and they were in a safe range of the structure. In addition, the linear actuator for the basic design is stable to the resonance by avoiding the natural frequencies of the components.

Analytical method for determination of 41Ca in radioactive concrete

  • Lee, Yong-Jin;Lim, Jong-Myoung;Lee, Jin-Hong;Hong, Sang-Bum;Kim, Hyuncheol
    • Nuclear Engineering and Technology
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    • v.53 no.4
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    • pp.1210-1217
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    • 2021
  • The analysis of 41Ca in concrete generated from the nuclear facilities decommissioning is critical for ensuring the safe management of radioactive waste. An analytical method for the determination of 41Ca in concrete is described. 41Ca is a neutron-activated long radionuclide, and hence, for accurate analysis, it is necessary to completely extract Ca from the concrete sample where it exists as the predominant element. The decomposition methods employed were the acid leaching, microwave digestion, and alkali fusion. A comparison of the results indicated that the alkali fusion is the most suitable way for the separation of Ca from the concrete sample. Several processes of hydroxide and carbonate precipitation were employed to separate 41Ca from interferences. The method relies on the differences in the solubility of the generated products. The behavior of Ca and the interfering elements such as Fe, Ni, Co, Eu, Ba, and Sr is examined at each separation step. The purified 41Ca was measured by a liquid scintillation counter, and the quench curve and counting efficiency were determined by using a certified reference material of known 41Ca activity. The recoveries in this study ranged from 56 to 68%, and the minimum detectable activity was 50 mBq g-1 with 0.5 g of concrete sample.

Experience of middle-aged female workers participating in cardio-cerebrovascular disease prevention management programs using mobile app (중년 여성 근로자의 모바일 앱을 활용한 심뇌혈관질환 예방관리 프로그램 참여 경험)

  • Yang, Hye Kyung
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.3
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    • pp.105-113
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    • 2021
  • This study is a qualitative study that conducted one-on-one in-depth interviews and focus group interviews to understand the meaning of the experience of participating in a cardio-cerebrovascular disease prevention management program using a mobile app for middle-aged female workers. The subjects of this study were 26 female workers over 50 years of age who participated in a cardio-cerebrovascular disease prevention program using a mobile app in a department store. Participating experience derived from the research result were 'Pleasure of getting to know', 'Activation of mutually friendly relations', 'health concerns take care of me ', 'Accepting an unfamiliar culture', 'Convenience as if receiving counseling anywhere. Through these results, it was shown that the mobile app improves the will to practice health behavior, and it is suggested that a standard to guarantee that the mobile app is a safe program is necessary to reduce anxiety about unfamiliar programs when installing the mobile app.

A Study on the Behavior of Sand Compaction Piles in Soft Ground (연약지반에 적용된 모래다짐말뚝의 거동특성에 관한 수치해석 연구)

  • Lee, Jungsang;Chung, sungrae;Chun, Byungsik
    • Journal of the Korean GEO-environmental Society
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    • v.12 no.8
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    • pp.33-38
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    • 2011
  • Presently, domestic SCP method with low replacement ratio is required as alternative in order to overcome the profitability of the sand resource because of the deficiency phenomenon of the sand resource by the actual condition design and construction is made by SCP method with low replacement ratio more than 70% for the port construction in the safe side. Sand compaction pile(SCP) method has been mainly used to improve the properties of soft clay or loose sandy ground. In design of SCP at soft clay ground, it is very important to determine the stress concentration ratio of composite ground relevant to the area replacement ratio. In this study, 2-dimensional FEM analyses were carried out to evaluate the stress concentration ratio of composite ground depending upon the area replacement ratio. When the interpretation result replacement ratio was 30%, the stress assigned rate showed and as the replacement ratio was high, the stress assigned rate according to the sinkage showed the low stress assigned rate.