• 대한토목학회논문집
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• 제32권3B호
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• pp.175-183
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• 2012

본 연구에서는 천수방정식에 Galerkin법과 Petrov-Galerkin 기법의 일종인 SU/PG 기법을 적용하여 유한요소 천수흐름 해석 모형을 개발하고, 다양한 실험수로에서 이송이 지배적인 흐름을 수치 모의하였다. 수로 내부에 얇은 판 형태의 구조물이 존재하는 경우 Fr 수와 Re 수가 매우 낮은 흐름에서는 Galerkin 기법과 SU/PG 기법이 동일한 결과를 나타냈으나, Fr=1.58인 경우 Galerkin법은 발산하여 해를 얻을 수 없었다. 이 경우 SU/PG법은 Newton-Raphson법에 의한 5회의 반복에 의해 수렴된 유속결과를 구할 수 있었다. 사류와 상류가 혼재하여 천이류가 나타나는 단면확대 수로 모의에서 SU/PG 기법을 이용한 본 연구의 경우 상류단 수심조건이 잘 유지되며, 도수가 발생하는 지점 및 도수에 의한 수심 경사, 도수 후의 수심이 모두 Khalifa(1980)의 실험결과와 매우 근사하였다. 이송이 지배적인 사류(Fr=2.74)에 의한 사각도수 모의의 경우에도 Galerkin 기법은 최초 모의시간의 첫 번째 반복 이후 발산하였으나, SU/PG 기법은 도수 경계면을 수치진동 없이 잘 포착하였으며, 해석해와 비교한 수심 및 유속의 최대 오차는 0.2% 이내로 나타나 기존 연구(Levin 등, 2006; Ricchiuto 등, 2007)에 비해 더욱 정확한 결과를 도출하였다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2004년도 학술발표회
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• pp.1331-1334
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• 2004

Wet/Dry phenomena typically incorporate a number of complex flow mechanism. These include a momentum transfer and turbulent mixing caused by the delivery of water. However currently available one dimensional schemes applicable to wet/dry process cannot effectively simulate such process. Two dimensional finite element model, SU/PG, is used to simulate complex flow in this study. The Wetted Area Method in SU/PG allows elements to transition gradually between wet and dry states. The model is applicable to a straight river reach with irregular bathymetry. Wet/dry calculation using the wetted area method can simulate simple numerical test. The computed results of velocity vectors and water depth agree with those of observed. The methodology Presented in this study will contributed to two-dimensional wet/dry analysis in a river in this country.

• 한국방재학회:학술대회논문집
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• 한국방재학회 2011년도 정기 학술발표대회
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• pp.198-198
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• 2011

The numerical simulation of dam break problem suffers from several challenges in terms of accuracy, stability, and versatility of the simulation algorithm since the water flow is generally discontinuous and presents abrupt variations. Thus, to obtain stable and accurate solutions, flow models for this purpose require numerical schemes provided with shock-capturing properties, and with the ability to work with flexible two-dimensional meshes. In this context, SU/PG method(Hughes and Brooks, 1979) is excellent candidate for the solution of the dam break problem. The weak formulation of the equations and the discontinuous polynomial basis lead to an accurate representation of bore waves(shocks). Furthermore, the discretization of the domain in finite elements is extremely effective in modeling complex geometries. In this study, a finite element model based on the SU/PG scheme is developed to solve shallow water equations and the model is applied to dam break problem. It is found that the present model accurately captures the bore wave that propagates downstream while spreading laterally and the depression wave that moves upstream. Furthermore, the propagation and formation of water surface profile compared favorably with those obtained by the previously published results.

• ETRI Journal
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• 제8권3호
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• pp.3-14
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• 1986

Currently, CIF is used widely as a common data base to represent IC layouts. The CIF2PG program is developed using C language to obtain electromask or mann 3000 PG file from the CIF input file. By obtaining the PG data, which can realize the actual mask layout, the construction of IC Design Automation System became possible using a general purpose computer.

• Journal of Microbiology and Biotechnology
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• 제34권4호
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• pp.812-827
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• 2024

Phloroglucinol (PG) is one of the abundant isomeric benzenetriols in brown algae. Due to its polyphenolic structure, PG exhibits various biological activities. However, the impact of PG on anagen signaling and oxidative stress in human dermal papilla cells (HDPCs) is unknown. In this study, we investigated the therapeutic potential of PG for improving hair loss. A non-cytotoxic concentration of PG increased anagen-inductive genes and transcriptional activities of β-Catenin. Since several anagen-inductive genes are regulated by β-Catenin, further experiments were performed to elucidate the molecular mechanism by which PG upregulates anagen signaling. Various biochemical analyses revealed that PG upregulated β-Catenin signaling without affecting the expression of Wnt. In particular, PG elevated the phosphorylation of protein kinase B (AKT), leading to an increase in the inhibitory phosphorylation of glycogen synthase kinase 3 beta (GSK3β) at serine 9. Treatment with the selective phosphoinositide 3-kinase/AKT inhibitor, LY294002, restored the increased AKT/GSK3β/β-Catenin signaling and anagen-inductive proteins induced by PG. Moreover, conditioned medium from PG-treated HDPCs promoted the proliferation and migration of human epidermal keratinocytes via the AKT signaling pathway. Subsequently, we assessed the antioxidant activities of PG. PG ameliorated the elevated oxidative stress markers and improved the decreased anagen signaling in hydrogen peroxide (H₂O₂)-induced HDPCs. The senescence-associated β-galactosidase staining assay also demonstrated that the antioxidant abilities of PG effectively mitigated H₂O₂-induced senescence. Overall, these results indicate that PG potentially enhances anagen signaling and improves oxidative stress-induced cellular damage in HDPCs. Therefore, PG can be employed as a novel therapeutic component to ameliorate hair loss symptoms.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권5호
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• pp.431-440
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• 2019

Purpose: No national survey has yet described the guidelines followed by Korean pediatricians to treat acute gastroenteritis (AGE). An online survey was performed to investigate the management of AGE followed by members of The Korean Society of Pediatric Gastroenterology, Hepatology, and Nutrition, and the results were compared between pediatric gastroenterologists (PG) and general pediatricians (GP). Methods: Questionnaires were sent to pediatricians between June 2 and 4, 2018 regarding the type of hospital, indications for admission, antiemetic and antidiarrheal drugs and antibiotics prescribed, and dietary changes advised. Results: Among the 400 pediatricians approached, 141 pediatricians (35.3%) responded to the survey. PG comprised 39% of the respondents and 72.7% worked at a tertiary hospital. Both PG and GP considered diarrhea or vomiting to be the primary symptom. The most common indication for hospitalization was severe dehydration (98.8%). Most pediatricians managed dehydration with intravenous fluid infusions (PG 98.2%, GP 92.9%). Antiemetics were prescribed by 87.3% of PG and 96.6% of GP. Probiotics to manage diarrhea were prescribed by 89.1% of PG and 100.0% of GP. Antibiotics were used in children with blood in diarrheal stool or high fever. Dietary changes were more commonly recommended by GP (59.3%) than by PG (27.3%) (p<0.05). Tests to identify etiological agents were performed primarily in hospitalized children. Conclusion: This survey assessing the management of pediatric AGE showed that the indications for admission and rehydration were similar between GP and PG. Drug prescriptions for diarrhea and dietary changes were slightly commonly recommended by GP than by PG.

• Journal of Animal Science and Technology
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• 제48권6호
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• pp.839-846
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• 2006

본 연구는 분만 전후 40두의 젖소에 무첨가, sucrose, sucrose+PG 및 sucrose+PG+NIS 복합제 첨가의 4 처리로 급여 시 사료섭취량, 산유량 혈중대사물질 및 대사성 질병 발생에 미치는 영향을 구명하기 위하여 사양시험을 수행하였는데, 주요 연구결과는 다음과 같다.분만전 건물섭취량은 처리 간에 차이가 없었지만 sucrose+PG+NIS 복합제를 투여하였을 때 대조구 보다 높았으며(P<0.05), sucrose 급여시 분만 후 3주 동안의 건물섭취량이 대조구에 비하여 유의있게 높았다(P<0.05). 혈중 glucose 함량은 처리 간에 유의적인 차이가 없었으나, 분만 전 21일 평균 NEFA 함량은 대조구에 비하여 sucrose+PG 혼합제를 투여한 처리구에서 유의있게 낮은 수준을 보여주었다 (P<0.05). 그러나 분만 당일 및 분만 후 21일 동안에는 처리 간에 유의적인 차이를 보여주지는 않았다. 처리구별 산유량에 있어서는 첨가제의 급여에 의한 차이를 보여주지 않았으나, 유지율에 있어서는 sucrose 급여구와 sucrose+PG+NIS 복합제를 급여한 구에서 대조구에 비하여 유의있게 높은 수준을 보여주었다. 그리고 4 % FCM에서는 대조구에 비하여 모든 처리구에서 유의있게 높았으며 (P<0.05), 대사성질병 발생은 대조구에서 첨가제 급여구에 비하여 다소 많은 개체에서 후산정체, ketosis 및 유방염이 발생하였다.본 시험의 결과에서 sucrose와 같이 단맛으로 기호성을 증진시켜주는 것과 에너지원으로 이용될 수 있는 PG와 함께 사료의 이용성을 높여줄 수 있는 NIS를 첨가하여 급여할 경우에 생산성을 높이고 대사성질병의 발생을 줄여 낙농농가의 생산성 향상에 기여할 수 있을 것으로 사료되었다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2003년도 학술발표회논문집(1)
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• pp.485-488
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• 2003

• TTA 저널
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• 통권128호
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• pp.77-81
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• 2010

• TTA 저널
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• 통권146호
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• pp.57-60
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• 2013