• BMB Reports
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• v.48 no.12
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• pp.702-707
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• 2015

To overcome the disadvantages of stem cell-based cell therapy like low cell survival at the disease site, we used stanniocalcin 2 (STC2), a family of secreted glycoprotein hormones that function to inhibit apoptosis and oxidative damage and to induce proliferation. STC2 gene was transfected into two kinds of stem cells to prolong cell survival and protect the cells from the damage by oxidative stress. The stem cells expressing STC2 exhibited increased cell viability and improved cell survival as well as elevated expression of the pluripotency and self-renewal markers (Oct4 and Nanog) under sub-lethal oxidative conditions. Up-regulation of CDK2 and CDK4 and down-regulation of cell cycle inhibitors p16 and p21 were observed after the delivery of STC2. Furthermore, STC2 transduction activated pAKT and pERK 1/2 signal pathways. Taken together, the STC2 can be used to enhance cell survival and maintain long-term stemness in therapeutic use of stem cells.

• 한국지구물리탐사학회:학술대회논문집
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• 2006.06a
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• pp.225-231
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• 2006

As a study of efficient velocity analysis in sonic log, several preexisting techniques have been adopted to the sonic data taken from model borehole in Kangwon National University, and the results were compared. For the data taken from monopole source, Slowness-Time Coherence method which is a common technique for nondispersive wave was used. For the data taken from dipole source, conventional STC and Tang's method(Tang et al., 1995) were used. From the good matches in the P and Stoneley wave velocities, we could confirm the effectiveness of STC computation. We also could find that shear velocity obtained from Tang's method were exactly matched with shear velocity obtained from monopole source, and that the velocity were within the range of S wave velocity values obtained from conventional STC application to dispersive flexural waves.

• Physical Therapy Rehabilitation Science
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• v.9 no.2
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• pp.74-81
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• 2020

Objective: To prevent low back pain, an objective evaluation tool to evaluate pelvic mobility and exercise to improve the flexibility of the lumbar region is needed. The purpose of this study was to compare the results of pelvic mobility measurements using the Wii Balance Board (WBB) and Sensbalance Therapy Cushion (STC), evaluate the usefulness of the STC as a tool for measuring pelvic mobility. Design: Cross-sectional study. Methods: Fifty healthy subjects participated in this study. The subjects performed pelvic mobility range, proprioception, reaction time and reach of the arm using the STC. The pelvic movement parameter was measured two times to determine the intra-rater reliability. To measure the correlation between lumbar muscle tension and pelvic mobility, Myovision was used to measure tension of L4, L5 level erector spinae muscle. Correlations between measured variables were checked to determine the validity of the pelvic mobility assessment tool. Results: STC showed high test-retest reliability in pelvic tilt measurement and reaching task [intraclass correlation coefficients (3,1)=0.804-0.915]. The relationship between WBB and STC showed a significant positive correlation with the pelvic tilt and reaching task (p<0.05). Posterior tilt and erector spinae activation (Lt. L5) showed a significant negative correlation (p<0.05). Left, right tilt and erector spinae activation (L5) showed a significant negative correlation (p<0.05). Conclusions: This study confirmed the advantages of the STC and found efficiency as an objective measuring device of pelvic mobility.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2004.11a
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• pp.272-273
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• 2004

• Proceedings of the PSK Conference
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• 2001.10a
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• pp.203.1-203.1
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• 2001

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.13 no.1
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• pp.5-14
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• 2003

Principles of a novel pulse growing method are described. The method realized in the crystal growing on a seed from melts under raw melt feeding provided a more reliable control of the crystallization process when producing large alkali halide crystals. The slow natural convection of the melt in the crucible at a constant melt level is intensified by rotating the crucible, while the crystal rotation favors a more symmetrical distribution of thermal stresses over the crystal cross-section. Optimum rotation parameters for the crucible and crystal have been determined. The spatial position oi the solid/liquid phase interface relatively to the melt surface, heaters and the crucible elements are considered. Basing on that consideration, a novel criterion is stated, that is, the immersion extent of the crystallization front (CF) convex toward the melt. When the crystal grows at a <> CF immersion, the raised CF may tear off from the melt partially or completely due to its weight. This results in avoid formation in the crystal. Experimental data on the radial crystal growth speed are discussed. This speed defines the formation of a gas phase layer at the crystal surface. The layer thickness il a function of time a temperature at specific values of pressure in the furnace and the free melt surface dimensions in the gap between the crystal and crucible wall. Analytical expressions have been derived for the impurity component mass transfer at the steady-state growth stage describing two independent processes, the impurity mass transfer along the <> path and its transit along the <> one. The heater (and thus the melt) temperature variation is inherent in any control system. It has been shown that when random temperature changes occur causing its lowering at a rate exceeding $0.5^{\circ}C/min$, a kind of the CF decoration by foreign impurities or by gas bubbles takes place. Short-term temperature changes at one heater or both result in local (i.e., at the front) redistribution of the preset axial growth speed.

• Journal of Radiation Protection and Research
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• v.28 no.3
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• pp.215-223
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• 2003

Against major release of radioactive material in nuclear power plant, Emergency Planning Zone(EPZ)s are typically established around nuclear power plants to effectively perform the public protective measures. The domestic methodology to determine the size of the EPZ is similar to that of Japan established in 1980, where calculations were based on the conservative accident source term. The objective of this study is to re-evaluate the validity of established EPZ, the area within the radius of $8{\sim}10km$ around domestic nuclear power plants, using the source terms covering full spectrum of accidents obtained from PSA study of ULJIN 3&4. To evaluate the risks of health effects, the computer code MACCS2(MELCOR Accident Consequence Code System2) was used. The result shows that the existing EPZ can reduce the probability of early fatality adequately for most of the source term categories(STCs) except for STC-14 and STC-19. In case of STC-14 and 19, the evacuation distance of 16km and 13km, respectively, are required. These distances can be reduced by improving emergency preparedness since the sensitivity studies for the public protective actions show that the magnitude of early fatality is largely affected by the time delays in notification and evacuation.

• Journal of the Korean Institute of Gas
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• v.4 no.1 s.9
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• pp.26-32
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• 2000

The fretting wear corrosion characteristics between the SM20C and the SM20C, the YBsC3 and the STC4H was experimented by using radical type friction experimental device under the corrosion environment of atmosphere, neutral solution, acid solution and chemical factors of the sea water. The affection of underground water that affect fretting wear corrosion of the SM20C which is moving specimen was more sensitive at the STC4H and more insensible at the YBsC3. The affection of underground water that affect fretting wear corrosion of the STC4H was less, but in the $0.5\%\;H_2SO_4$ and $0.5\%\;HNO_3$ solutions the fretting wear corrosion of the STC4H was more large. The fretting wear corrosion of the SM20C which is moving specimen in the underground water was less than in the $3.5\%\;NaCl$, $0.5\%\;H_2SO_4$ and $0.5\%\;HNO_3$ solutions. As time passed, the fretting wear corrosion is increased in the $HNO_3$ solution and dull in the $0.5\%\;H_2SO_4$ solution.

• Animal Bioscience
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• v.36 no.2
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• pp.256-263
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• 2023

Objective: Feed molecular structures can affect its availability to gastrointestinal enzymes which impact its digestibility and absorption. The molecular spectroscopy-attenuated total reflectance Fourier transform infrared vibrational spectroscopy (ATR-FTIR) is an advanced technique that measures the absorbance of chemical functional groups on the infrared region so that we can identify and quantify molecules and functional groups in a feed. The program aimed to reveal the association of intrinsic molecular structure with nutrient supply to animals from canola feedstocks and co-products from bio-oil processing. The objective of this study was to characterize special intrinsic carbohydrate and protein-related molecular structure spectral profiles of feedstock and co-products (meal and pellets) from bio-oil processing from two source origins: Canada (CA) and China (CH). Methods: The samples of feedstock and co-products were obtained from five different companies in each country arranged by the Canola Council of Canada (CCC). The molecular structure spectral features were analyzed using advanced vibrational molecular spectroscopy-ATR-FTIR. The spectral features that accessed included: i) protein-related spectral features (Amide I, Amide II, α-helix, β-sheet, and their spectral intensity ratios), ii) carbohydrate-related spectral features (TC1, TC2, TC3, TC4, CEC, STC1, STC2, STC3, STC4, TC, and their spectral intensity ratios). Results: The results showed that significant differences were observed on all vibrationally spectral features related to total carbohydrates, structural carbohydrates, and cellulosic compounds (p<0.05), except spectral features of TC2 and STC1 (p>0.05) of co-products, where CH meals presented higher peaks of these structures than CA. Similarly, it was for the carbohydrate-related molecular structure of canola seeds where the difference between CA and CH occurred except for STC3 height, CEC and STC areas (p>0.05). The protein-related molecular structures were similar for the canola seeds from both countries. However, CH meals presented higher peaks of amide I, α-helix, and β-sheet heights, α-helix:β-sheet ratio, total amide and amide I areas (p<0.05). Conclusion: The principal component analysis was able to explain over 90% of the variabilities in the carbohydrate and protein structures although it was not able to separate the samples from the two countries, indicating feedstock and coproducts interrelationship between CH and CA.

• The Transactions of the Korean Institute of Power Electronics
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• v.17 no.3
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• pp.191-197
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• 2012

This paper proposes a new synthetic test circuit (STC) to confirm the switching operation of thyristor valve in HVDC converter. The proposed STC uses a 6-pulse thyristor converter with 2-phase chopper as a high-current source to provide turn-on current to the test valve. The operation of proposed STC was verified through theoretical analysis and computer simulations. Based on computer simulations, a hardware scaled model was built and tested to confirm the feasibility of implementing a real-size test facility. The proposed system has an advantage of simple structure and operation over the existing system.