• BMB Reports
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• 제48권12호
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• pp.702-707
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• 2015

To overcome the disadvantages of stem cell-based cell therapy like low cell survival at the disease site, we used stanniocalcin 2 (STC2), a family of secreted glycoprotein hormones that function to inhibit apoptosis and oxidative damage and to induce proliferation. STC2 gene was transfected into two kinds of stem cells to prolong cell survival and protect the cells from the damage by oxidative stress. The stem cells expressing STC2 exhibited increased cell viability and improved cell survival as well as elevated expression of the pluripotency and self-renewal markers (Oct4 and Nanog) under sub-lethal oxidative conditions. Up-regulation of CDK2 and CDK4 and down-regulation of cell cycle inhibitors p16 and p21 were observed after the delivery of STC2. Furthermore, STC2 transduction activated pAKT and pERK 1/2 signal pathways. Taken together, the STC2 can be used to enhance cell survival and maintain long-term stemness in therapeutic use of stem cells.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2006년도 공동학술대회 논문집
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• pp.225-231
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• 2006

음파검층을 사용하여 획득한 파형으로부터 정확한 속도분석을 하기 위한 연구의 일환으로 일반적으로 많이 이용되고 있는 STC 방법(Slowness-Time Coherence)을 비롯하여, 파의 분산성을 고려한 Tang et al.의 방법(1995)을 검층시험용 모형공에 적용해 보고 그 결과를 비교하였다. P파와 Stoneley파 에서는 매우 일관된 속도값을 보여 STC방법의 효과가 확인되었다. Tang et al.의 방법(1995)에서 구해진 S파 속도는 monopole source의 S파속도와 잘 일치되고 dipole source의 자료에 대한 monopole technique의 STC방법에서의 S파속도 범위 내에 있는 것이 확인되었다.

• Physical Therapy Rehabilitation Science
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• 제9권2호
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• pp.74-81
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• 2020

Objective: To prevent low back pain, an objective evaluation tool to evaluate pelvic mobility and exercise to improve the flexibility of the lumbar region is needed. The purpose of this study was to compare the results of pelvic mobility measurements using the Wii Balance Board (WBB) and Sensbalance Therapy Cushion (STC), evaluate the usefulness of the STC as a tool for measuring pelvic mobility. Design: Cross-sectional study. Methods: Fifty healthy subjects participated in this study. The subjects performed pelvic mobility range, proprioception, reaction time and reach of the arm using the STC. The pelvic movement parameter was measured two times to determine the intra-rater reliability. To measure the correlation between lumbar muscle tension and pelvic mobility, Myovision was used to measure tension of L4, L5 level erector spinae muscle. Correlations between measured variables were checked to determine the validity of the pelvic mobility assessment tool. Results: STC showed high test-retest reliability in pelvic tilt measurement and reaching task [intraclass correlation coefficients (3,1)=0.804-0.915]. The relationship between WBB and STC showed a significant positive correlation with the pelvic tilt and reaching task (p<0.05). Posterior tilt and erector spinae activation (Lt. L5) showed a significant negative correlation (p<0.05). Left, right tilt and erector spinae activation (L5) showed a significant negative correlation (p<0.05). Conclusions: This study confirmed the advantages of the STC and found efficiency as an objective measuring device of pelvic mobility.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2004년도 학술대회지
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• pp.272-273
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• 2004

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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• pp.203.1-203.1
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• 2001

• 한국결정성장학회지
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• 제13권1호
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• pp.5-14
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• 2003

Principles of a novel pulse growing method are described. The method realized in the crystal growing on a seed from melts under raw melt feeding provided a more reliable control of the crystallization process when producing large alkali halide crystals. The slow natural convection of the melt in the crucible at a constant melt level is intensified by rotating the crucible, while the crystal rotation favors a more symmetrical distribution of thermal stresses over the crystal cross-section. Optimum rotation parameters for the crucible and crystal have been determined. The spatial position oi the solid/liquid phase interface relatively to the melt surface, heaters and the crucible elements are considered. Basing on that consideration, a novel criterion is stated, that is, the immersion extent of the crystallization front (CF) convex toward the melt. When the crystal grows at a <> CF immersion, the raised CF may tear off from the melt partially or completely due to its weight. This results in avoid formation in the crystal. Experimental data on the radial crystal growth speed are discussed. This speed defines the formation of a gas phase layer at the crystal surface. The layer thickness il a function of time a temperature at specific values of pressure in the furnace and the free melt surface dimensions in the gap between the crystal and crucible wall. Analytical expressions have been derived for the impurity component mass transfer at the steady-state growth stage describing two independent processes, the impurity mass transfer along the <> path and its transit along the <> one. The heater (and thus the melt) temperature variation is inherent in any control system. It has been shown that when random temperature changes occur causing its lowering at a rate exceeding $0.5^{\circ}C/min$, a kind of the CF decoration by foreign impurities or by gas bubbles takes place. Short-term temperature changes at one heater or both result in local (i.e., at the front) redistribution of the preset axial growth speed.

• Journal of Radiation Protection and Research
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• 제28권3호
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• pp.215-223
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• 2003

원자력발전소로부터의 만일의 방사성물질 누출사고에 대비해 원자력발전소 주변에는 주민보호조치를 효율적으로 수행하기 위해 비상계획구역이 설정되어 있다. 그러나 이러한 비상계획구역 크기를 결정하는 국내의 방법론은 보수적인 사고선원항을 이용하여 계산한 1980년에 발표된 일본의 이론에 근거하고 있다. 본 연구의 목적은 울진 3&4호기의 확률론적 안전성점검 연구결과로 얻어진 사고선원항을 토대로 현재 원전을 중심으로 반경 $8{\sim}10km$의 주변지역으로 설정되어 있는 방사선 비상계획구역의 적합성을 재평가하는 것이다. 방사선영향평가를 위해서 컴퓨터 코드인 MACCS2(MELCOR Accident Consequence Code System2)코드를 사용하였다. 연구결과는 현재 울진원전을 중심으로 설정되어 있는 반경 $8{\sim}10km$의 비상계획구역으로서 STC-14 및 STC-19를 제외한 대부분의 선원항들에 대해 조기사망 발생확률을 크게 낮출 수 있음을 보여주고 있다. STC-14의 경우는 16km 이상, STC-19의 경우는 13km이상 소개되어야 조기사망 발생확률이 현저하게 감소되었다. 주민보호조치에 대한 민감도 분석결과에서는 사고통보 및 소개와 관련된 시간지연이 조기사망효과에 대해 직접적이고도 매우 큰 영향을 주고 있음을 확인할 수 있었다.

• 한국가스학회지
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• 제4권1호
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• pp.26-32
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• 2000

본 연구에서는 힌지재인 SM20C, YBsC3 및 STC4H재에 대하여 공기 및 여러 가지 부식환경중에서 이종금속간의 찰과마멸부식실험을 실시하여, 이종금속간의 찰과마멸부식특성에 미치는 환경조건의 영향을 연구하였으며, 주요 결론은 다음과 같다. 1) 이동측 금속인 SM20C의 찰과마멸부식에 미치는 지하수의 영향은 STC4H에서 더 민감하고 YBsC3에서는 둔화된다. 2) STC4H의 찰과마멸부식에 미치는 지하수의 영향은 작지만, $0.5\%\;H_2SO_4$ 및 $0.5\%HNO_3$ 용액중에서 더 크게 된다. 3) 이동측 SM20C의 찰과마멸부식은 $3.5\%\;NaCl$, $0.5\%\;H_2SO_4$ 및 $0.5\%\;HNO_3$ 용액중에서보다 지하수중에서 가장 작게 나타났다. 4) 시간이 경과함에 따라 찰과마멸부식에 미치는 영향은 $0.5\%\;HNO_3$ 용액중에서는 증가하지 $0.5\%\;H_2SO_4$ 용액중에서는 둔화된다.

• Animal Bioscience
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• 제36권2호
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• pp.256-263
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• 2023

Objective: Feed molecular structures can affect its availability to gastrointestinal enzymes which impact its digestibility and absorption. The molecular spectroscopy-attenuated total reflectance Fourier transform infrared vibrational spectroscopy (ATR-FTIR) is an advanced technique that measures the absorbance of chemical functional groups on the infrared region so that we can identify and quantify molecules and functional groups in a feed. The program aimed to reveal the association of intrinsic molecular structure with nutrient supply to animals from canola feedstocks and co-products from bio-oil processing. The objective of this study was to characterize special intrinsic carbohydrate and protein-related molecular structure spectral profiles of feedstock and co-products (meal and pellets) from bio-oil processing from two source origins: Canada (CA) and China (CH). Methods: The samples of feedstock and co-products were obtained from five different companies in each country arranged by the Canola Council of Canada (CCC). The molecular structure spectral features were analyzed using advanced vibrational molecular spectroscopy-ATR-FTIR. The spectral features that accessed included: i) protein-related spectral features (Amide I, Amide II, α-helix, β-sheet, and their spectral intensity ratios), ii) carbohydrate-related spectral features (TC1, TC2, TC3, TC4, CEC, STC1, STC2, STC3, STC4, TC, and their spectral intensity ratios). Results: The results showed that significant differences were observed on all vibrationally spectral features related to total carbohydrates, structural carbohydrates, and cellulosic compounds (p<0.05), except spectral features of TC2 and STC1 (p>0.05) of co-products, where CH meals presented higher peaks of these structures than CA. Similarly, it was for the carbohydrate-related molecular structure of canola seeds where the difference between CA and CH occurred except for STC3 height, CEC and STC areas (p>0.05). The protein-related molecular structures were similar for the canola seeds from both countries. However, CH meals presented higher peaks of amide I, α-helix, and β-sheet heights, α-helix:β-sheet ratio, total amide and amide I areas (p<0.05). Conclusion: The principal component analysis was able to explain over 90% of the variabilities in the carbohydrate and protein structures although it was not able to separate the samples from the two countries, indicating feedstock and coproducts interrelationship between CH and CA.

• 전력전자학회논문지
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• 제17권3호
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• pp.191-197
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• 2012

This paper proposes a new synthetic test circuit (STC) to confirm the switching operation of thyristor valve in HVDC converter. The proposed STC uses a 6-pulse thyristor converter with 2-phase chopper as a high-current source to provide turn-on current to the test valve. The operation of proposed STC was verified through theoretical analysis and computer simulations. Based on computer simulations, a hardware scaled model was built and tested to confirm the feasibility of implementing a real-size test facility. The proposed system has an advantage of simple structure and operation over the existing system.