• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 추계학술발표회
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• pp.274-275
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• 2011

• 미생물학회지
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• 제30권3호
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• pp.171-186
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• 1992

Lipolytic characteristics of candia cylindracea lipase was studied by various triacylglycerols with different fatty acyl chains as substrate. The substrate was emulsified with gum arabic and the rate of hydrolysis was determined by pH stat method. The effects of gum concentration, pH, temperature, and $Ca^{2+}$ ion on the enzyme activities were examined. The results show that the effect of these factors are markedly depending on the structurla nature of substrates. The triolein was the best substrate among tested. Present study demonstrates that for characterization of lipolytic enzymes, it is critically important to select proper substrate and activator.r.

• Communications for Statistical Applications and Methods
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• 제8권2호
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• pp.507-514
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• 2001

In recent years, the development and the embodiment of information analysis system has been sprightly carried out in several fields of study. In this study, as and extension of these studies, we develop a system for multivariate analysis which might be widely used in social and natural sciences. This multivariate analysis system is developed by using multivariate analysis procedures in SAS/STAT software. Also, the system supply users with he environment of GUI(Graphical User Interface), which is constructed with AF(application frame) and SCL(screen control language) of SAS software, in order to help users to use the system with easy.

• 한국미생물·생명공학회지
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• 제22권4호
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• pp.401-406
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• 1994

The medium compositions of Alcaligenes eutrophus were optimized for increasing PHB productivity. It is very important to optimize the concentrations of inorganic salts and trace eleme- nts as well as carbon and nitrogen sources to maximize cell growth rate and productivity. The fed-batch culture of Alcaligenes eutrophus by dual feeding of ammonia water and glucose under optimized initial medium concentrations was carried out. Glucose was fed manually according to glucose consumption rate and ammonia water by pH-stat. The final cell concentrations and PHB content in 30 hours were 122 g/l and 65% of dry cell weight(yielding 79 g of PHB/l), respectively and 2.64 g/l/hr of PHB production rate was obtained.

• 한국초전도저온공학회:학술대회논문집
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• 한국초전도저온공학회 1999년도 제1회 학술대회논문집(KIASC 1st conference 99)
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• pp.34-38
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• 1999

An acoustic emission(AE) technique has been used to monitor and diagnose quenching phenomenon in racetrack shaped superconducting magnets at cryogenic environment of 4.2K. The ultimate goal is to ensure the safety and reliability of large superconducting magnet systems by being able to identity and locate the sources of quench in superconducting magnets. The characteristics of AE parameters have been analyzed by correlating with quench number, winding tension of superconducting coil and charge rate by transport current. It was found in this study stat there was good correlation between quench current and AE parameters. The source location of quenching in superconducting magnet was also discussed on the correlation between magnet voltage and AE energy.

• Journal of Microbiology and Biotechnology
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• 제9권6호
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• pp.722-725
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• 1999

Filamentation-suppressed recombinant Escherichia coli strain harboring the Alcaligenes latus polyhydroxyalkanoate (PHA) biosynthesis genes and the E. coli ftsZ gene was constructed and cultivated for the production of poly(3-hydroxybutyrate) [P(3HB)] with high concentration and high content. By the pH-stat fed-batch culture of this recombinant E. coli strain XL1-Blue(pJC5), the final cell concentration and P(3HB) concentration obtained in 44.25h were 172.2g cell dry weight/l and 141.9g P(3HB)/l, respectively, resulting in productivity of 3.21g P(3HB)/l-h. More importantly, the P(3HB) content obtained was 82.4 wt %, which was significantly higher than that obtained with the recombinant E. coli harboring only the PHA biosynthesis genes.

• 디지털산업정보학회논문지
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• 제8권2호
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• pp.81-94
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• 2012

This paper suggests PARED algorithm, a modified RED algorithm, that actively reacts to dynamic changes in network to apply packet drop probability flexibly. The main idea of PARED algorithm is that it compares the target queue length to the average queue length which is the criterion of changes in packet drop probability and feeds the gap into packet drop probability. That is, when the difference between the average queue length and the target queue length is great, it reflects as much as the difference in packet drop probability, and reflects little when the difference is little. By doing so, packet drop probability could be actively controled and effectively dealt with in the network traffic situation. To evaluate the performance of the suggested algorithm, we conducted simulations by changing network traffic into a dynamic stat. At the experiments, the suggested algorithm was compared to the existing RED one and then to ARED one that provided the basic idea for this algorithm. The results proved that the suggested PARED algorithm is superior to the existing algorithms.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2001년도 가을 학술발표논문집 Vol.28 No.2 (3)
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• pp.379-381
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• 2001

본 논문에서는 가입자함의 광대역화 밀 고속화를 실현하는 방안으로 개발되고 있는 광대역 무선가입자망(B-WLL) 시스템 기지국장치의 MAC 프로토콜을 설계하고 구현하였다. MAC 프로토콜은 제한된 무선자원을 효율적으로 사용하기 위한 프로토콜로서 , 무선매체를 이용하여 통신서비스를 제공하는 시스템에 필수적이다. 본 논문에서 설계한 기지국장치 MAC 프로토콜은 실시간처리부, 타이밍관련처리부, MPEG2-TS 관련처리부. 그리고 CRC 처리부를 하드웨어로 설계하고. 이론 제어하고 MAC 프로토콜 동작절차를 수행하는 부분을 MAC 프로토콜 소프트웨어를 설계하였다. MAC 소프트웨어는 MAC 응용부 Network 인터페이스부, 콘솔입출력 처리부로 나누어 설계하였으며, 본 논문에서 설계된 기지국장치 MAC 프로토플은 향후. B-WLL 시스템의 실제 테스트베드로 이용하여 시스템의 전체적인 성능을 검증할 수 있다.

• BMB Reports
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• 제49권2호
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• pp.128-133
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• 2016

Astrocytes play a critical role in normal brain functions and maintaining the brain microenvironment, and defects in astrocytogenesis during neurodevelopment could give rise to severe mental illness and psychiatric disorders. During neuro-embryogenesis, astrocytogenesis involves astrocytic differentiation of neural precursor cells (NPCs) induced by signals from ciliary neurotrophic factor (CNTF) or pituitary adenylate cyclase-activating peptide (PACAP). However, in contrast to the CNTF signaling pathway, the exact mechanism underlying astrocytic differentiation induced by PACAP is unknown. In the present study, we aimed to verify a signaling pathway specific to PACAP-induced astrocytogenesis, using exchange protein directly activated by cAMP2 (Epac2)-knockout mice. We found that PACAP could trigger astrocytic differentiation of NPCs via Epac2 activation and an increase in the intracellular calcium concentration via a calcium ion influx. Taken together, we concluded that astrocytogenesis stimulated by PACAP occurs through a novel signaling pathway independent from CNTF-JAK/STAT signaling, that is the well-known pathway of astrocytogenesis.

• BMB Reports
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• 제47권10호
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• pp.581-586
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• 2014

Epidermal growth factor (EGF) is known to play key roles in skin regeneration and wound-healing. Here, we demonstrate that Pep2-YAC, a tripeptide covering residues 29-31 in the B loop of EGF, promotes the proliferation of HaCaT keratinocytes with activity comparable to EGF. The treatment of HaCaT cells with Pep2-YAC induced phosphorylation, internalization, and degradation of EGFR and organization of signaling complexes, which consist of Grb2, Gab1, SHP2, and PI3K. In addition, it stimulated the phosphorylation of ERK1/2 at Thr 202/Tyr 204 and of Akt1 at Ser 473 and the nuclear translocation of EGFR, STAT3, c-Jun, and c-Fos. These results suggest that Pep2-YAC may be useful as a therapeutic agent for skin regeneration and wound-healing as an EGFR agonist.