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Growth Characteristic and Productivity of Forage Corn Varieties Sown at the Last Ten Days of May in Central Region of Korea (중부지역에서 5월 하순 파종한 사료용 옥수수의 품종별 생육특성과 조사료 생산성)

  • Choi, Gi Jun;Jung, Jeong Sung;Choi, Ki Choon;Hwang, Tae Young;Kim, Ji Hye;Kim, Won Ho;Lee, Eun Ja;Sung, Kyung Il;Lee, Ki-Won
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.39 no.1
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    • pp.17-23
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    • 2019
  • This experiment was carried out to evaluate the characteristic and productivity of forage corn varieties sown at the last ten days of May at Cheonan of Korea on 2017 and 2018. Forage corn varieties sown on 24th May 2017 and $25^{th}$ May 2018 were emerged in 5th and 1st June, respectively. Silking date of forage corns was different among varieties(p<0.05). Stem length of forage corns was not different among the varieties, except Kwangpyeongok(KPA) and Nero IT. Stem diameter of forage corns was not different amaong the varieties. Outbreak rate of black streaked dwarf virus was lower than 3% in all varieties. Total digestible nutrient(TDN) yield was different among corn varieties(p<0.05), which was higher in P32P75, followed by P2088, P31N27, and KPA. The TDN yield of varieties had direct correlation with stem length, stem diameter and ear yield, respectively(p<0.01). Average of TDN in all varieties was 69.8%. These results suggested that forage corn variety with late-seeding adaptability is more important for increasing the productivity of forage corn If harvesting of winter forage crops have to be finished in the middle ten days of May in middle region of Korea.

Effect of Cyclic Injection on Migration and Trapping of Immiscible Fluids in Porous Media (공극 구조 내 교차 주입이 비혼성 유체의 포획 및 거동에 미치는 영향)

  • Ahn, Hyejin;Kim, Seon-ok;Lee, Minhee;Wang, Sookyun
    • Economic and Environmental Geology
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    • v.52 no.1
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    • pp.37-48
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    • 2019
  • In geological $CO_2$ sequestration, the behavior of $CO_2$ within a reservoir can be characterized as two-phase flow in a porous media. For two phase flow, these processes include drainage, when a wetting fluid is displaced by a non-wetting fluid and imbibition, when a non-wetting fluid is displaced by a wetting fluid. In $CO_2$ sequestration, an understanding of drainage and imbibition processes and the resulting NW phase residual trapping are of critical importance to evaluate the impacts and efficiencies of these displacement process. This study aimed to observe migration and residual trapping of immiscible fluids in porous media via cyclic injection of drainage-imbibition. For this purpose, cyclic injection experiments by applying n-hexane and deionized water used as proxy fluid of $scCO_2$ and pore water were conducted in the two dimensional micromodel. The images from experiment were used to estimate the saturation and observed distribution of n-hexane and deionized water over the course drainage-imbibition cycles. Experimental results showed that n-hexane and deionized water are trapped by wettability, capillarity, dead end zone, entrapment and bypassing during $1^{st}$ drainage-imbibition cycle. Also, as cyclic injection proceeds, the flow path is simplified around the main flow path in the micromodel, and the saturation of injection fluid converges to remain constant. Experimental observation results can be used to predict the migration and distribution of $CO_2$ and pore water by reservoir environmental conditions and drainage-imbibition cycles.

Immune Checkpoint Inhibitors for Non-Small-Cell Lung Cancer with Brain Metastasis : The Role of Gamma Knife Radiosurgery

  • Lee, Min Ho;Cho, Kyung-Rae;Choi, Jung Won;Kong, Doo-Sik;Seol, Ho Jun;Nam, Do-Hyun;Jung, Hyun Ae;Sun, Jong-Mu;Lee, Se-Hoon;Ahn, Jin Seok;Ahn, Myung-Ju;Park, Keunchil;Lee, Jung-Il
    • Journal of Korean Neurosurgical Society
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    • v.64 no.2
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    • pp.271-281
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    • 2021
  • Objective : Immune checkpoint inhibitors (ICIs) are approved for treating non-small-cell lung cancer (NSCLC); however, the safety and efficacy of combined ICI and Gamma Knife radiosurgery (GKS) treatment remain undefined. In this study, we retrospectively analyzed patients treated with ICIs with or without GKS at our institute to manage patients with brain metastases from NSCLC. Methods : We retrospectively reviewed medical records of patients with brain metastases from NSCLC treated with ICIs between January 2015 and December 2017. Of 134 patients, 77 were assessable for brain responses and categorized into three groups as follows : group A, ICI alone (n=26); group B, ICI with concurrent GKS within 14 days (n=24); and group C, ICI with non-concurrent GKS (n=27). Results : The median follow-up duration after brain metastasis diagnosis was 19.1 months (range, 1-77). At the last follow-up, 53 patients (68.8%) died, 20 were alive, and four were lost to follow-up. The estimated median overall survival (OS) of all patients from the date of brain metastasis diagnosis was 20.0 months (95% confidence interval, 12.5-27.7) (10.0, 22.5, and 42.1 months in groups A, B, and C, respectively). The OS was shorter in group A than in group C (p=0.001). The intracranial disease progression-free survival (p=0.569), local progression-free survival (p=0.457), and complication rates did not significantly differ among the groups. Twelve patients showed leptomeningeal seeding (LMS) during follow-up. The 1-year LMS-free rate in treated with ICI alone group (69.1%) was significantly lower than that in treated with GKS before ICI treatment or within 14 days group (93.2%) (p=0.004). Conclusion : GKS with ICI showed no favorable OS outcome in treating brain metastasis from NSCLC. However, GKS with ICI did not increase the risk of complications. Furthermore, compared with ICI alone, GKS with ICI may be associated with a reduced incidence of LMS. Further understanding of the mechanism, which remains unknown, may help improve the quality of life of patients with brain metastasis.

Effect of Community-Based 'Goal-Achieving Program' in Patient with Late-Life Depression : Preliminary Study (노인성 우울증 환자에서 지역사회 기반 '목표달성 프로그램'의 효용성 : 예비 연구)

  • Kang, Gyu Ha;Chang, Ki Jung;Lim, Hyun Kook;Han, Jin joo;Lee, Eun Hee;Roh, Hyun Woong;Noh, Jai Sung;Chung, Young Ki;Lim, Ki Young;Hong, Chang Hyung;Son, Sang Joon
    • Journal of Korean geriatric psychiatry
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    • v.21 no.1
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    • pp.35-40
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    • 2017
  • Objective : This study aimed to investigate the effect of community-based Goal-Achieving program in geriatric depressive symptoms preliminarily. Methods : We obtained data from elderly Korean subjects with major depressive disorder (n=51) aged 60 years or older at baseline, taking case management from community mental health center. Subjects were randomly assigned to intervention group (n=24) and control group (n=27). We investigated depressive symptoms through Short Form Geriatric Depression Scale-Korean version (SGDS-K) at baseline and every month for 3 months to all subjects. We tested interaction between group and time in SGDS-K score to evaluate the effect of program. And post hoc test examined between group differences of SGDS-K at each time points. Results : In quadratic linear mixed effects model analysis, interaction between group and time was statistically significant (Total SGDS-K score : coefficient=0.29, p<0.001 ; SGDS-K dysphoria subscale : 0.18, p<0.001 ; SGDS-K hopelessness subscale : 0.05, p=0.089 ; SGDS-K cognitive impairment subscale : 0.06, p=0.003). And significant between group difference was shown in post hoc test at time points of third month (SGDS-K score of control group : SGDS-K score of intervention group=$10.74{\pm}3.482$ : $7.25{\pm}4.475$, p=0.0184). Conclusion : These results may suggest that 'Community-based the Goal-Achieving program' has efficacy in reducing geriatric depressive symptoms.

Changes in Feeding Habit and Body Composition of Black Sea Bream Acanthopagrus schlegeli Released in Eelgrass Zostera marina Bed (잘피밭 해역에 방류된 감성돔 Acanthopagrus schlegeli 치어의 식성 및 어체성분 변화)

  • Ji, Seung-Cheol;Lee, Si-Woo;Kim, Yang-Su;Jeong, Gwan-Sik;Yoo, Jin-Hyung;Choi, Nack-Jung;Myeong, Jeong-Gu
    • Journal of Aquaculture
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    • v.21 no.4
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    • pp.278-284
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    • 2008
  • Artificially-produced juvenile black sea bream Acanthopagrus schlegeli (total length $8.3{\pm}1.0\;cm$, body weight $11.2{\pm}4.2\;g$) were released in eelgrass, Zostera marina bed and their initial food organism and changes of body compositions were investigated for one month after release. Predation rates in fish sampled on 1st and 3rd days were 79%, increased up to 100% on 7th and 10th days, and then decreased on 30th days as 75%. Major prey organisms was composed of mainly Amphipoda and Gastropoda. Ratio of Amphipoda and Gastropoda in stomach were highest in fish sampled on 15th and 1st days after release, respectively. Crustacea and Algae were maintained about 20% during a sampling period. Visceral weight index (VWI) offish sampled 20th and 30th after release were significantly higher than that of initial. Carcass crude protein and lipid contents of released fish were showed significantly decreasing; however carcass n-3 HUFA composition was showed increasing tendency with the passage of time after release. Eelgrass bed was supposed to be helpful for the released fish to adjust their feeding habits and biochemical metabolism to the natural environment within a short period after release.

COMPARATIVE ACCURACY OF THE SPLINTED AND UNSPLINTED IMPRESSION METHODS FOR INTERNAL CONNECTION

  • Choi, Jung-Han;Kim, Chang-Whe;Jang, Kyung-Soo;Lim, Young-Jin
    • The Journal of Korean Academy of Prosthodontics
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    • v.43 no.3
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    • pp.352-362
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    • 2005
  • Statement of problem. Accurate impression is essential to success of implant prostheses. But there have been few studies about the accuracy of fixture-level impression techniques in internal connection implant systems. Purpose. The purpose of this study was to compare the accuracy of two fixture-level impression techniques in two conditions (parallel and divergent) and to assess the effect of tightening sequences and forces on stresses generated on superstructures in internal connection implant system (Astra Tech). Material and methods. Two metal master frameworks made from two abutments (Cast-to Abutment ST) each and a corresponding, passively fitting, dental stone master cast with four fixture replicas (Fixture Replica ST) were fabricated. Ten dental stone casts for each impression techniques (direct unsplinted & splinted technique) were made with vinyl polysiloxane impressions from the master cast. Strain gauges for each framework were fixed midway between abutments to measure the degree of framework deformation on each stone cast. Pairs of strain gauges placed opposite each other constituted one channel (half Wheatstone bridge) to read deformation in four directions (superior, inferior, anterior, and posterior). Deformation data were analyzed using one-way ANOVA and the Tukey test at the .01 level of significance. And the effect of tightening sequences (right-to-left and left-to-right) and forces (10 Ncm and 20 Ncm) were assessed with ten stone casts made from parallel condition by the splinted technique. Deformation data were analyzed using paired t-test at the .01 level of significance. Conclusions. Within the limitations of this study, the following conclusions could be drawn. 1. Frameworks bent toward the inferior side on all casts made by both direct unsplinted and splinted impression techniques in both parallel and divergent conditions. 2. There was no statistically significant difference of accuracy between the direct unsplinted and splinted impression techniques in both parallel and divergent conditions (P>.01). 3. There was no statistically significant difference of stress according to screw tightening sequences in casts made by the splinted impression technique in parallel condition (P>.01). 4. Greater tightening force resulted in greater stress in casts made by the splinted impression technique in parallel condition (P<.01).

Stress Analysis on the Splinted Conditions of the Two Implant Crowns with the Different Vertical Bone Level (치조골 높이가 다른 2개 임플란트 금관의 고정연결 조건에 따른 응력분석)

  • Jeon, Chang-Sik;Jeong, Sin-Young;Kang, Dong-Wan
    • Journal of Dental Rehabilitation and Applied Science
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    • v.21 no.2
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    • pp.169-182
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    • 2005
  • The purpose of this study was to compare the stress distribution around the surrounding bone according to the splinted and non-splinted conditions on the finite element models of the two implant crowns with the different vertical bone level. The finite element model was designed with the parallel placement of the two fixtures ($4.0mm{\times}11.5mm$) with reverse buttress thread on the mandibular 1st and 2nd molars. As the bone quality, the inner cancellous bone and the outer 2 mm cortical bone were designed, and the cortical and cancellous bone were assumed to be perfectly bonded to the implant fixture. The splinted model(Model 1) had 2 mm contact surface and the non-splinted model(Model 2) had $8{\mu}m$ gap between two implant crowns. Two group (Splinted and non-splinted) was loaded with 200 N magnitude in the vertical and oblique directions on the loading point position on the central position of the crown, the 2 mm and 4 mm buccal offset point from the central position. Von Mises stress value was recorded and compared in the fixture-bone interface in the bucco-lingual and mesio-distal sections. The results were as follows; 1. In the vertical loading condition of central position, the stress was distributed on the cortical bone and the cancellous bone around the thread of the fixture in the splinted and non-splinted models. In the oblique loading condition, the stress was concentrated toward the cortical bone of the fixture neck, and the neck portion of 2nd molar in the non-splinted model was concentrated higher than that of 1st molar compared to the splinted model. 2. In the 2 mm buccal offset position of the vertical loading compared to the central vertical loading, stress pattern was shifted from apical third portion of the fixture to upper third portion of that. In the oblique loading condition, the stress was distributed over the fixture-bone interface. 3. In the 4 mm buccal offset position of the vertical loading, stress pattern was concentrated on the cortical bone around the buccal side of the fixture thread and shifted from apical third portion of the fixture to upper third portion of that in the splinted and non-splinted models. In the oblique loading, stresses pattern was distributed to the outer position of the neck portion of the fixture thread on the mesio-distal section in the splinted and non-splinted models. Above the results, it was concluded that the direction of loading condition was a key factor to effect the pattern and magnitude of stress over the surrounding bone of the fixture under the vertical and oblique loading conditions, although the type with or without proximal contact did not effect to the stress distribution.

Systematic Relationships Among Ten Species of Subgenus Drosophila (Diptera: Drosophilidae) in Korea (한국 초파리아속(쌍시목: 초파리과) 10종에 대한 계통적 유연관계)

  • Nam Woo Kim;Eun Young Joo
    • Animal Systematics, Evolution and Diversity
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    • v.19 no.2
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    • pp.167-176
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    • 2003
  • This study sought to observe systematic relationships through taximetrical analyses by morphological characters among the 10 species, on three species in the virilis section (D. virilis, D. tsigana and D. lacertosa) and seven species in the quinaria section (D. angularis, D. brachvnephros, D. curvispina, D. kuntzei, D. nigromaculata, D. takadai and D. unispina) of the subgenus Drosophila. In the cluster and the cladistic analysis among the members of subgenus Drosophila, 10 species was divided into the 1st group of D. virilis, D. tsigana, and D. lacertosa and the 2nd group of D. angularis, D. brachynephros, D. curvispina, D. kuntzei, D. nigromaculata, D. takadai, and D. unispina. In cluster analysis, the 2nd group had three sister groups; one sister group that clustered D. angularis and D. brachynephros then D. unispina was clustered to them, another sister group clustered D, curvispina and D. takadai then D. kuntzei was clustered to them and the other sister group of D. nigromaculata. In the 10 species, D. virilis and D. lacertosa were the first to be divided and then D. tsigana. Although 1st group which D. virilis was belonged can be determined as more primitive than the 2nd group, it seemed that this group was not the direct ancestor of the 2nd group, rather there should be another ancestor. Among the quinaria species group, D. nigromaculata was the first to be divided and D. kuntzei was the most recent species to be divided.

Developing Self-awareness Through Cyber Study and Cyber Reading Activities: A Case Study with the Electronic Library 'Booktoby' (사이버 학습을 활용한 학생의 자아정체성 확인에 관한 연구: 북토비 사례를 중심으로)

  • Kang, Hyon-Sook
    • Journal of Information Technology and Architecture
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    • v.11 no.4
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    • pp.485-494
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    • 2014
  • This study has been conducted with $1^{st}$ grade elementary students where the purpose was to develop students' interest in themselves and to cultivate their self-awareness as the first step toward establishing a suitable course and career for their start-up features. Students have conducted the cyber study through "Incheon e-School" and cyber reading "Booktoby" and recorded three types of outcomes - affective self-awareness, social self-awareness and intelligence self-awareness - on each side of the Pyramid, thus constructing their own self-awareness pyramids of the system. According to the results, after such activities were undertaken during the $1^{st}$ semester, their opinion toward their self-control and study ability has improved as much as about 67% compared to that of the beginning of the last semester. Regarding the effects of cyber reading, their interest, spontaneity and understanding toward reading books have also improved as much as 54% and 50%, 33% respectively along with positive answers of as much as 75% with regard to self-awareness. When it comes to the results of the SCI-II test (used to evaluate self-awareness), the total average has improved by as much as 3 points and the three components of self-awareness - affective, social, and intelligence - have improved by as much as 4points, 1point, and 5points, respectively.

Effect of Cattle Manure Application on Forage Productivity and Soil Characteristics of Pasture (방목초지에서 우분 퇴비 시용이 목초생산 및 토양에 미치는 영향)

  • Hwang, Kyung-Jun;Ko, Seo-Bong;Park, Hyung-Soo;Park, Nam-Gun;Ko, Moon-Suck;Kim, Moon-Chul;Song, Sang-Teak
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.27 no.1
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    • pp.45-52
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    • 2007
  • This study was conducted from 2003 to 2005 at crop field of National Institute of Subtropical Agriculture, RDA, in Jeju. The treatment consisted of chemical fertilizer 100%(CF 100%, T1), cattle manure 100%(CM 100%, T2), CF 50%+CM 50%(T3), CF 25%+CM 75%(T4), CM 100%(1st yr.)+CF 100%(2nd yr,)+CM(3rd yr)(T5), CM 100%(1st yr.)+CF 100%(2nd yr.)+CF(3rd yr.)(T6). The highest substitution effect of chemical fertilizer for cattle manure indicated that the highest yield(Avg. 11,169 kg/ha) obtained from CM 100%(1 yr.)+CF 100%(2 yr.) treatment. The forage yield of CM 100%(1 yr.)+CF 100%(2 yr.) was 4% more than CM 100% application whereas was 3% less than CF 100% application. Changes of physical and chemical properties of soils for applications of CF 100% and CM 100% was clearly in cattle manure application. Especially, cattle manure application in pasture were superior to chemical fertilizer application with respect to organic matter(OM, %), total nitrogen(T-N, %), and avaliable phosphorous($P_2O_5$, %) contents of soils. In this present study, cattle manure application recorded slightly lower forage yields than CF 100% application but the combined use of cattle manure and chemical fertilizer was attribute to reduction of chemical fertilizer application rate as well as maintaining soil health on long-term basis.