• Title/Summary/Keyword: ST

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Molecular Epidemiology of Bacillus cereus in a Pediatric Cancer Center (소아 암 환자에서 발생한 Bacillus cereus 균혈증의 분자역학 분석에 관한 연구)

  • Kim, Jong Min;Park, Ki-Sup;Lee, Byung-Kee;Kim, Soo Jin;Kang, Ji-Man;Kim, Yanghyun;Yoo, Keon Hee;Sung, Ki Woong;Koo, Hong Hoe;Lee, Nam Yong;Kim, Yae-Jean
    • Pediatric Infection and Vaccine
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    • v.23 no.3
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    • pp.172-179
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    • 2016
  • Purpose: Bacillus cereus has been reported as the cause of nosocomial infections in cancer patients. In our pediatric cancer ward, a sudden rise in the number of patients with B. cereus bacteremia was observed in 2013 to 2014. This study was performed to investigate the molecular epidemiology of increased B. cereus bacteremia cases in our center. Methods: Pediatric cancer patients who developed B. cereus bacteremia were identified from January 2001 to June 2014. The B. cereus bacteremia in this study was defined as a case in which at least one B. cereus identified in blood cultures, regardless of true bacteremia. Available isolates were further tested by multilocus sequence typing (MLST) analysis. A retrospective chart review was performed. Results: Nineteen patients developed B. cereus bacteremia during the study period. However, in 2013, a sudden increase in the number of patients with B. cereus bacteremia was observed. In addition, three patients developed B. cereus bacteremia within 1 week in July and the other three patients within 1 week in October, respectively, during emergency room renovation. However, MLST analysis revealed different sequence types without consistent patterns. Before 2013, five tested isolates were ST18, ST26, ST177, and ST147-like type, and ST219-like type. Isolates from 2013 were ST18, ST73, ST90, ST427, ST784, ST34-like type, and ST130-like type. Conclusions: MLST analyses showed variable ST distribution of B. cereus isolates. Based on this study, there was no significant evidence suggesting a true outbreak caused by a single ST among patients who developed B. cereus bacteremia.

Enhancement of ST-segment Features in ECG Signals by Warping Transformation (워핑 변환을 이용한 심전도 신호의 ST 분절 특징 값 강화)

  • Shin, Seung-Won;Kim, Kyeong-Seop
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.6
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    • pp.1143-1149
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    • 2010
  • In this study, we propose a novel method to detect and enhance the feature of ST-segment which offers the crucial information for the diagnosis of myocardial infarction and ischemia. With this aim, PQRST features of Electrocardiogram initially are detected and subsequently ST-segment are estimated. And Dynamic Time Warping(DTW) transformation is applied recursively to minimize the difference in time between ST-segments and calculate the minimum cumulative distance that decides the degree of similarity among ST-segments. As of the results, the inherent characteristic of ST-segment can be emphasized in terms of time parameter and thus the diagnostic features of a ST-segment can be revealed further.

Development of Surface Finishing Methodology for the Laminated Pattern Removal of VLM-ST Parts (VLM-ST 시작품의 적층무늬 제거를 위한 표면처리 방법론 개발)

  • Lee Sang-Ho;Kim Hyo-Chan;Song Min-Sup;Yang Dong-Yol
    • Journal of the Korean Society for Precision Engineering
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    • v.22 no.2
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    • pp.202-209
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    • 2005
  • A new effective thick-layered RP process, Transfer-type Variable Lamination Manufacturing using expandable polystyrene foam (VLM-ST) has been developed with thick layers and sloped surfaces. VLM-ST has the innate advantages by virtue of its working principle: high building speed, low cost for introduction and maintenance of VLM-ST apparatus, little staircase surface irregularities of parts. Despite these advantages in VLM-ST, the surface roughness of VLM-ST parts is still inadequate to be used as RP master patterns for rapid tooling (RT). This paper describes the systematic and effective methodology to remove the laminated pattern and improve the surface roughness for VLM-ST parts. From the results of surface finishing of VLM-ST parts, it can be seen that the laminated pattern is completely removed and the surface characteristics such as surface roughness, surface hardness, and paintability are improved.

Realtime Wireless Monitoring of Abnormal ST in ECG Using PC Based System

  • Jeong, Gu-Young;Yu, Kee-Ho;Kim, Nam-Gyun;Inooka, Hikaru
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.176-180
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    • 2004
  • The ST-segment that the beginning part of T wave is the important diagnostic parameter to finding myocardial ischemia. Abnormal ST appears in two types. One is the level change, and the other is the pattern change. In this paper, we describe the monitoring of abnormal ST using PC based system. Hardware of this system consists of transmitter, receiver and PC. The function of transmitter is measuring ECG in three channels which are selected manually and transmitting the data to receiver by digital radio way. Connection with receiver and PC is by RS232C, and the data received on the PC is analyzed automatically by ECG analysis algorithm and saved to file. In the algorithm part for detecting abnormal ST, ST-segments are approximated by a polynomial. This method can detect all of the deviation and pattern change of ST-segment regardless the change in the heart rate or sampling rate. To gain algorithm reliability, the method rejects distorted polynomial approximation by calculation the difference between the approximated ST-segment and original ST-segment. In pre-signal processing, the wavelet transformation separates high frequency bands including QRS complex from the original ECG. Consequently, the process improves the performance of detecting each feature points.

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Dielectric and Strain Properties of PMN-PT Ceramics Doped with $\textrm{SrTiO}^3$ and excess MgO ($\textrm{SrTiO}^3$ 와 과잉 MgO가 첨가된 $\textrm{Pb(Mg_{1/3}Nb_{2/3})O}_3$ - $\textrm{PbTiO}^3$ 계 세라믹스의 유전 및 변위 특성)

  • 이상훈
    • Journal of the Korean Institute of Telematics and Electronics T
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    • v.36T no.3
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    • pp.7-12
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    • 1999
  • In this paper, dielectric and strain properties of (1-f-y)PMN-yPT-xST ceramics investigated with the amount of $\textrm{SrTiO}^3$(ST). The $\textrm{SrTiO}^3$ content is ranged within 1~6㏖%. Another compositions with excess MgO also investigated. As the amount of ST is increased, dielectric constant has a maximum value at 5㏖% composition. The Curie temperature is decreased linearly with increasing the amount of ST. Coercive field and ramnant polarization has a maximum value at l㏖% composition. As for the effects of excess MgO, the dielectric constant has been increased by the addition of excess MgO up to 3㏖% to a 0.8PMN-0.12PT-0.04ST specimen. But the strain has been decreased by the addition of excess MgO.

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Microflora of the Lower Part of the Nagdong River (낙동상 하류 수역의 Microflora)

  • 김용관;이태식;신일식
    • Journal of Environmental Health Sciences
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    • v.16 no.2
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    • pp.47-53
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    • 1990
  • This experiment was carried out to evaluate general characteristics of the water quality, total coliform, fecal coliform and microflora at the St. 1 to St. 3 and St. 4 to St. 7. Eighty-four water samples were collected from the 7 stations from July 1988 to April 1990 (see Fig. 1) Range and mean value of the samples were as follows water temperature 2.0-29.9$^{\circ}$C, 16.3$^{\circ}$C pH 6.86-9.08, 7.62: electrical conductivity 54.85$\mu \mho$/cm, 4.300 m$\mho$/cm, 911.93 $\mu \mho$/cm : turbidity 0.9-36 NTU, 6.8 NTU, respectively. pH and electrical conductivity at St. 4 to St. 7 were higher than those at St. 1 to St. 3, but turbidity at St. 1 to St. 2 was 7 times higher than that at Sonagdong river area. The bacterial density of the samples ranged 91-110,000/100ml for total coliform. 21-15,000/100ml for fecal coliform. Specially, the geometric mean value of the St. 3 was 11,836 / 100ml for it leveled heavy contaminaiton. Predominant species among the 3,874 strains isolated form the samples were 30.6% Enterobacteriaceae, 14.7% Acinetobacter, 9.0% Aeromonas. 8.9% Neisseria, and 7.5% Vibrio.

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Effects of Bovine Somatotropin (bST) Administration Combined with Controlled Internal Drug Release (CIDR) on Embryo Quality and Pregnancy of Hanwoo (Korean Native Beef Cattle) during Commercial Embryo Transfer Program

  • Lee, Ho-Jun;Hwang, Seongsoo;Yoon, Jong-Taek
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.2
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    • pp.194-199
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    • 2007
  • Effects of recombinant bovine somatotropin (bST) on plasma hormonal concentration, embryo quality, and pregnancy rate were examined during the superovulation and synchronization treatment in donor and recipient cows. Hanwoos (Korean native beef cattle) were treated with controlled internal drug release (CIDR) combined with bST (CIDR+bST) or without bST (CIDR) as donor cows. The embryos recovered from donors were transferred into Holstein recipient heifers treated with bST (CIDR+bST) or without bST (CIDR) for synchronization. The correlation between IGF-I and P4 showed a positive pattern in the CIDR+bST group (r=0.44, p<0.01), but a negative pattern was shown in the CIDR group (r = -0.59, p<0.02) at day 7 of estrous cycles. Although the number of recovered, transferable, and degenerated embryos was not different, quantities of grade 1 (excellent) embryos in CIDR+bST group were significantly higher than those of the CIDR group (p<0.01). The pregnancy rate was higher in the CIDR+bST recipient group compared to CIDR group (p<0.05), when the embryos were recovered from the donors treated with CIDR. However, the pregnancy was maintained highly in both recipient groups, when the embryos were produced by CIDR+bST treated donors. It can be concluded that bST administration combined with CIDR is an effective method for superovulation and synchronization treatment to stabilize plasma hormonal levels, to obtain excellent quality of embryos, and to get higher pregnancy rate.

The Evaluation of Water Quality in Coastal Sea of Saemangeum by Chemical Environmental factors (새만금 하구역의 이화학적 환경요인에 따른 수질 평가)

  • Kim, Jae-Ok;Kim, Won-Jang;Jo, Kuk-Hyun
    • Journal of The Korean Society of Agricultural Engineers
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    • v.49 no.5
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    • pp.57-65
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    • 2007
  • The objective of this study was to evaluate chemical water quality by hourly monitoring(25hr) of Saemangeum esturary. For this study, we selected 2 sites like a Mangyong Bridge(St. 6) and Dongjin Bridge(St. 7). Inflow of salt water was not detected during low tide(maximum 553, 508cm) of all stations, while the salinity rises were detected in spring tide(750cm). When 602m of maximum tide was reached, salinity concentration was increased at St. 7, while there was no change in St. 6. Therefore, We know that salinity variation is greatly influenced by tide height at survey site. Also, significant variance of salinity(p<0.05) was found between St. 6 and St. 7 because dike construction made the flood tide move into the Dongjin river. Total suspened solids(TSS) concentration was increased because of the river runoff at St. 6, and also the turbulance and resuspension according to salt intrusion at St. 7. During the high tide, the water discharge from the sea seemed to dilute the nutrient but to elevate TSS concentration in St. 7. Silicate and nitrate concentrations in the studied site were decreased by the mixing of sea water, whereas the evident trend of phosphate concentration was not found. This result can be explained by the phosphorus condition. Phosphorus exists inactive when it is affected by hydrated iron and adsorbed onto suspended matters. Compared to the environmental conditions of the St. 6 and St. 7, physical factors such as temperature, dissolved oxygen and TSS have statistically no significant difference(p<0.001), but nutrient concentrations were higher at St. 6 than St. 7. It could be suggested from these results that it is important to control the discharge of fresh water by sewage treatment plants located in St. 6 for water quality management.

Experimental Studies on the Change of Cytotoxic and Antitumor Effects according to the Prebrewed Method of Semen Tiglii and Rhizoma Coptidis (수치파두(修治巴豆) 및 파두가황연(巴豆加黃連)의 세포독성(細胞毒性)과 항종양(抗腫瘍) 효과(效果)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Jo, Soung-Gak;Moon, Goo;Moon, Suk-Jae
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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    • v.1 no.1
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    • pp.191-211
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    • 1995
  • This experiment was designed to study the change of cytotoxic and antitumor effects according to the prebrewed method of Semen Tiglii and Rhizoma Coptidis. The cytotoxic and antitumor effects were evaluated on human cell lines(A 549, Caki-1, LL2, Sarcoma 180, NIH/3T3) after exposure to prebrewed Semen Tiglii and Rhizoma Coptidis water extract 0.1, 0.2, 0.4, 0.8, 1.6 mg/ml using in MTT assay, LDH, colony forming efficency and SRB assay which were regarded as a valuable method for cytotoxic and antitumor effects of unknown compound on tumor cell lines. The results obtained in this studies were as follows. 1. The cytotoxicity from the result of MTT assay was low slightly in the ST II(炒巴豆霜), high in the ST III(醋炒巴豆). The cytotoxicity of ST I + RC(生巴豆霜加黃連) was similar to that of STI(生巴豆霜). 2. The cytotoxicity from the result of LDH was low slightly in the ST Ⅱ (炒巴豆霜), high in the ST III(醋炒巴豆). The cytotoxicity of ST I + RC(生巴豆霜加黃連) was similar to that of ST I(生巴豆霜). 3. The antitumor affect on A 549 tumor cell from the result of colony forming efficiency was low slightly in the ST II (炒巴豆霜) and ST I + RC(生巴豆霜加黃連). 4. The antitumor effect on Caki-1 tumor cell from the result of SRB assay was low slightly in the ST II (炒巴豆霜). 5. Median survival time and Increased life span increased slightly in the ST I RC(生巴豆霜加黃連) and ST II (炒巴豆霜). 6. The inhibitory effect on the growth of Sarcoma 180 and Lewis lung carcinoma tumor cell increased slightly in the ST I + RC(生巴豆霜加黃連) and ST II (炒巴豆霜).

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Clinical Outcomes of Stent Thrombosis after Drug-Eluting Coronary Stent Implantation (약물방출 관상동맥 스텐트 시술 후 스텐트 혈전증 발생 환자의 임상경과)

  • Kim, In-Soo;Jeong, Myoung-Ho;Han, Jae-Bok;Jang, Young Ill;Jang, Seong-Joo
    • The Journal of the Korea Contents Association
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    • v.13 no.12
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    • pp.880-892
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    • 2013
  • Stent thrombosis after successful drug-eluting stent(DES) implantation has been reported in around 1% of patients in clinical trials. However, the increased risk of ST associated with DES remains a matter of concern. From 1 June 2003 to 30 June 2013, we investigated clinical characteristics, in-hospital outcomes in 10,273 patients who underwent percutaneous coronary intervention in the Heart Center of CNUH. Overall incidence of ST was 1.30% (134 patients). The incidence of ST according to the stent generations and the timing of ST (n=total, early vs. late vs. very late) were 0.79% (n=81, 26 vs. 12 vs. 43) in first-generation, 0.38% (n=39, 21 vs. 9 vs. 9) in second-generation and 0.14% (n=14, 8 vs 3 vs. 3) in third-generation, (p=0.70). The mortality from ST was significantly higher in early ST group compared to the late and very late ST groups (18.2% vs. 8.3% vs. 3.6%, p=0.042). Overall incidence of ST after DES implantation was 1.30% (134 patients). The in-hospital mortality was significantly higher in early ST group compared to the late and very late ST groups.