• Title/Summary/Keyword: SRD

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The Clinical Application of modified Emory Functional Ambulation Profile for Chronic Stroke Patients (만성 편마비 환자의 modified Emory Functional Ambulation Profile의 임상 적용)

  • Kim, Seong-Yeol;Lee, Je-Hoon;An, Seung-Heon
    • Journal of the Korean Society of Physical Medicine
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    • v.5 no.4
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    • pp.655-666
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    • 2010
  • Purpose : The examine the reliability and validity of the modified Emory Functional Ambulation Profile(mEFAP) for assessing gait function in chronic stroke patients. Methods : A total of 45 stroke patients, who had a stroke more than 6 months, participated in the study. Reliability was determined by Intra-class Correlation Coefficient($ICC_{3,1}$), including Bland and Altman method (Standard Error of Measurement: SEM, Small Real Differences: SRD). Validity was examined by correlating results to the gait ability(mEFAP, Modified Motor Assessment Scale-Gait(MMAS-G), Scandinavian Stroke Scale-Gait(SSS-G), Functional Ambulation Category(FAC), 10m Waking Test(10m WT)), and Fugl Meyer-Lower/Extremity(FM-L/E), Berg Balance Scale(BBS). Results : Inter-rater reliability for the total mEFAP was High($ICC_{2,1}$=.998), and absolute reliability were excellent (SEM: 1.75, SRD: 4.85). Subjects without assistance factor performed better on all tests than did subjects who had stroke. There were significant correlations between the mEFAP and MMAS-G, SSS-G, FAC(r=-.66~-.79), 10 m WT(r=-.86), and FM-L/E, BBS(r=-.72~-.78), indicating good validity. Increased times on the mEFAP correlated with poor performance on the gait ability, motor function of lower extremity, BBS and slow gait speeds on the 10 m WT in stroke patients. Conclusion : The mEFAP can be administered easily and comprehensively. It is a reliable gait assessment tool for patients with stroke and correlated with known of function, the mEFAP may be a clinically useful measure of ambulation.

A Yield Estimation Model of Forage Rye Based on Climate Data by Locations in South Korea Using General Linear Model

  • Peng, Jing Lun;Kim, Moon Ju;Kim, Byong Wan;Sung, Kyung Il
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.36 no.3
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    • pp.205-214
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    • 2016
  • The objective of this study was to construct a forage rye (FR) dry matter yield (DMY) estimation model based on climate data by locations in South Korea. The data set (n = 549) during 29 years were used. Six optimal climatic variables were selected through stepwise multiple regression analysis with DMY as the response variable. Subsequently, via general linear model, the final model including the six climatic variables and cultivated locations as dummy variables was constructed as follows: DMY = 104.166SGD + 1.454AAT + 147.863MTJ + 59.183PAT150 - 4.693SRF + 45.106SRD - 5230.001 + Location, where SGD was spring growing days, AAT was autumnal accumulated temperature, MTJ was mean temperature in January, PAT150 was period to accumulated temperature 150, SRF was spring rainfall, and SRD was spring rainfall days. The model constructed in this research could explain 24.4 % of the variations in DMY of FR. The homoscedasticity and the assumption that the mean of the residuals were equal to zero was satisfied. The goodness-of-fit of the model was proper based on most scatters of the predicted DMY values fell within the 95% confidence interval.

Association of Benign Prostate Hyperplasia with Polymorphisms in VDR, CYP17, and SRD5A2 Genes among Lebanese Men

  • El Ezzi, Asmahan Ali;Zaidan, Wissam Rateeb;El-Saidi, Mohammed Ahmed;Al-Ahmadieh, Nabil;Mortenson, Jeffrey Benjamin;Kuddus, Ruhul Haque
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.3
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    • pp.1255-1262
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    • 2014
  • Background: The aim of the study was to investigate any associations between benign prostate hyperplasia (BPH) and single nucleotide polymorphisms (SNPs) in the VDR gene (FokI, BsmI, ApaI and Taq${\alpha}$I loci) and the CYP17 gene (MspA1I locus), as well as TA repeat polymorphism in SRD5A2 gene among Lebanese men. Materials and Methods: DNA extracted from blood of 68 subjects with confirmed BPH and 79 age-matched controls was subjected to PCR/PCR-restriction fragment length polymorphism analysis. The odds ra=tio (OR) of having a genotype and the relative risk (RR) of developing BPH for having the genotype were calculated and the alleles were designated risk-bearing or protective. Results: Our data indicated that the A and B alleles of the VDR ApaI and BsmI SNPs were highly associated with increased risk of BPH (p=0.0168 and 0.0002, respectively). Moreover, 63% of the controls compared to 43% of the subjects with BPH were homozygous for none of the risk-bearing alleles (p=0.0123) whereas 60% of the controls and 28% of the subjects with BPH were homozygous for two or more protective alleles (p<0.0001). Conclusions: For the first time, our study demonstrated that ApaI and BsmI of the VDR gene are associated with risk of BPH among Lebanese men. Our study also indicated that overall polymorphism profile of all the genes involved in prostate physiology could be a better predictor of BPH risk.

Development of Multiscale Modeling Methods Coupling Molecular Dynamics and Stochastic Rotation Dynamics (분자동역학과 확률회전동역학을 결합한 멀티스케일 모델링 기법 개발)

  • Cha, Kwangho;Jung, Youngkyun
    • KIISE Transactions on Computing Practices
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    • v.20 no.10
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    • pp.534-542
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    • 2014
  • Multiscale modeling is a new simulation approach which can manage different spatial and temporal scales of system. In this study, as part of multiscale modeling research, we propose the way of combining two different simulation methods, molecular dynamics(MD) and stochastic rotation dynamics(SRD). Our conceptual implementations are based on LAMMPS, one of the well-known molecular dynamics programs. Our prototype of multiscale modeling follows the form of the third party implementation of LAMMPS. It added MD to SRD in order to simulate the boundary area of the simulation box. Because it is important to guarantee the seamless simulation, we also designed the overlap zones and communication zones. The preliminary experimental results showed that our proposed scheme is properly worked out and the execution time is also reduced.

Analysis of Frequency Sharing Performance using Guard Band and User Device Density in a Urban Environment (도심 환경에서 보호대역과 단말밀도를 이용한 주파수 공유성능 분석)

  • Cho, Ju-Phil
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.16 no.9
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    • pp.1864-1869
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    • 2012
  • We make an interference analysis to obtain a critical ctiteria for coexisting availability of WLAN and WiBro between adjacent channels can be used in TVWS(TV White Space). To meet this analysis, we set the various transmission parameters including the emission and blocking mask, antenna height and gain, transmission power and bandwidth, channel model etc. And, based on these parameters, we analyze on performances according to a variation of guard band, a number of service user and allowable transmit power of the user operating in the adjacent channels. In this paper, we consider a urban environment and apply a Extended Hata-SRD for WLAN and an interference link and Extended Hata model for WiBro, respectively. With these results, we can see how each system can be shared in an adjacent channel.

Investigation on the effect of water extracts of Mangifera indica leaves on the hair loss-related genes in human dermal papilla cells (망고 잎 열수 추출물의 모유두 세포에서 탈모 관련 유전자 발현에 미치는 영향 연구)

  • Choi, Youngsoo;Kim, Eunmi;Lee, Seong Hee;Han, Hyosang;Kim, Keekwang
    • The Korea Journal of Herbology
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    • v.36 no.3
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    • pp.39-46
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    • 2021
  • Objectives : Mangifera indica leaves are well known for having a variety of benefits, including anti-inflammatory, anti-tumor, diabetic retinopathy and diabetic vasculosis. However, the effects of Mangifera indica leaves on hair loss inhibition have not been studied. In this study, we investigated to find out the activity of Mangifera indica leaves on hair loss. Methods : 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid(ABTS) analysis was performed to confirm the antioxidant efficacy of the water extract of Mangifera indica leaves (WEML). To examine the effect of WEML on cell viability in dermal papillar (DP) cells, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetra Zolium (MTS) analysis was performed. The changes in the mRNA expression level of the hair loss and hair growth-related genes in dermal papilla cells by WEML treatment were confirmed by quantitative RT-PCR. Results : In dermal papilla (DP) cells, ABTS analysis and MTS analysis of WEML showed antioxidant efficacy and low cytotoxicity. As a result of gene expression analysis through Quantitative RT-PCR, no changes in hair growth-related genes BMP6 and CTNNB1 was confirmed. but inhibitory activity of WEML on hair loss-related genes EGR1, SGK, DKK1, SRD5A1 and SRD5A2 was confirmed. Conclusion : We confirmed that WEML has excellent antioxidant efficacy and a inhibitory activity of hair loss-related genes including 5α-reductase genes. These results suggest that Mangifera indica leaves have a potential activity as a hair loss treatment for hair loss and hair growth. Biochemical or molecular biological research on hair loss is needed.

Prediction of the Italian Ryegrass (Lolium multiflorum Lam.) Yield via Climate Big Data and Geographic Information System in Republic of Korea (기상 빅 데이터와 지리정보시스템을 이용한 이탈리안 라이그라스의 수량예측)

  • Kim, Moonju;Oh, Seung Min;Kim, Ji Yung;Lee, Bae Hun;Peng, Jinglun;Kim, Si Chul;Chemere, Befekadu;Nejad, Jalil Ghassemi;Kim, Kyeong Dae;Jo, Mu Hwan;Kim, Byong Wan;Sung, Kyung Il
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.37 no.2
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    • pp.145-153
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    • 2017
  • This study was aimed to find yield prediction model of Italian ryegrass using climate big data and geographic information. After that, mapping the predicted yield results using Geographic Information System (GIS) as follows; First, forage data were collected; second, the climate information, which was matched with forage data according to year and location, was gathered from the Korean Metrology Administration (KMA) as big data; third, the climate layers used for GIS were constructed; fourth, the yield prediction equation was estimated for the climate layers. Finally, the prediction model was evaluated in aspect of fitness and accuracy. As a result, the fitness of the model ($R^2$) was between 27% to 95% in relation to cultivated locations. In Suwon (n=321), the model was; DMY = 158.63AGD -8.82AAT +169.09SGD - 8.03SAT +184.59SRD -13,352.24 (DMY: Dry Matter Yield, AGD: Autumnal Growing Days, SGD: Spring Growing Days, SAT: Spring Accumulated Temperature, SRD: Spring Rainfall Days). Furthermore, DMY was predicted as $9,790{\pm}120$ (kg/ha) for the mean DMY(9,790 kg/ha). During mapping, the yield of inland areas were relatively greater than that of coastal areas except of Jeju Island, furthermore, northeastern areas, which was mountainous, had lain no cultivations due to weak cold tolerance. In this study, even though the yield prediction modeling and mapping were only performed in several particular locations limited to the data situation as a startup research in the Republic of Korea.

A Study on 433Mhz Hardware Design of CC1020 (CC1020을 이용한 433Mhz H/W 설계에 관한 연구)

  • Yang, Si-Pyoung;Jo, Heung-Kuk
    • Proceedings of the Korea Institute of Convergence Signal Processing
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    • 2005.11a
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    • pp.343-346
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    • 2005
  • 유비쿼터스 시대의 도래로 인해 많은 IT업체는 유비쿼터스 핵심기술을 기반으로 발전하고 있다. 이러한 유비쿼터스 핵심기술의 상당부분은 무선통신기술 RF를 이용한 것이며 이를 활용하여 RFID 시스템 및 Ubiquitous Sensor Network 등을 구축할 수 있다. 본 논문에서는 이에 적합한 400/800MHz ISM/SRD 밴드대역을 사용하는 무선 트렌시버 단일 칩인 CC1020을 이용하여 하드웨어를 구성 하였다. CC1020칩을 사용하면 저전력, 고감도, 적은 주변회로 구성 등 많은 이점이 있으며 주파수원 고정과 필터링 및 전원공급상태 그리고 PC와의 interface등의 하드웨어를 쉽게 구현할 수 있다. 따라서 이러한 각 주변회로 구성에 대해 설명하고 실제 구현을 통해 DATA의 송수신실험을 통해 하드웨어의 특성을 확인 하였다.

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Analysis of the Phase Locked Microwave Oscillator Characteristics on the P-HEMT Gate-Bias Tuning (P-HEMT Gate-바이어스 튜닝에 의한 위상동기 마이크로파 발진기 특성분석)

  • 정인기;민상보;이영철
    • Proceedings of the IEEK Conference
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    • 2000.11a
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    • pp.369-372
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    • 2000
  • 본 논문에서는 P-HEMT Gate-바이어스 튜닝에 의한 위상동기 마이크로파 발진기를 설계하였다. 설계된 유전체 발진기는 병렬궤환공진 형태로서 P-HEMT의 게이트단에서 전압을 제어하여 전압제어발진기 형태로 주파수를 가변시키므로서 안정된 위상동기신호를 나타나도록 하였다. 위상동기방식은 외부에서 제공되는 125㎒의 기준주파수를 SRD로 체배시켜 하모닉 신호를 이용한 마이크로파 샘플링 위상검파 방식으로 설계하였으며, 유전체 발진기의 자유발진신호와 샘플링 신호사이의 위상비교에 의하여 ±1㎒ 범위의 고안정 특성을 갖는 13.25㎓대역의 위상고정 발진기의 동기화와 저 위상잡음을 나타내었다.

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Fundametal Design for Switched Reluctance Motor (Switched Reluctance Motor의 기본설계)

  • Jang, S.M.;Seo, J.H.;Jeong, S.S.;Seong, S.J.
    • Proceedings of the KIEE Conference
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    • 1996.07a
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    • pp.219-221
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    • 1996
  • A reluctance motor is a electric machine in which torque is produced by the tendency of its movable part to move to a position where the inductance of the excited winding is maximized. This means physical fact that the energy stored in the field tend to be minimized as the energy stored in the field is converted the mechanical work. In this paper, we have studied the characteristics of the electromagnetic energy conversion about SRM which have 6 stator and 4 rotor poles with 3 phase. In addition we design the fundamental model of SRM with requirements(e.g. power, speed) and simulate with PC-SRD.

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