• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 1996년도 특별강연 및 춘계학술발표 개요집
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• pp.186-189
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• 1996

A study was made to examine the characteristics of base metal and stress relief cracking(SRC) of heat affected zone(HAZ) for HY-100 and Cu-bearing HSLA-100 steels. The Gleeble thermal/mechanical simulator was used to simulate the SRC/HAZ. The details of mechanical properties of base plate and SRC tested specimens were studied. The specimens were aged at $650^{\circ}C$ for HSLA-100 steel and at 66$0^{\circ}C$ for HY-100 steel and thermal cycled from 135$0^{\circ}C$ In $25^{\circ}C$ with a cooling time of $\Delta$ $t_{800^{\circ}50}$ $0^{\circ}C$/=21sec. corresponds to the heat input of 30kJ/cm. The thermal cycled specimens were stressed to a predetermined level of 248~600MPa and then reheated to the stress relief temperatures of 570~62$0^{\circ}C$. The time to failure( $t_{f}$) at a given stress level was used as a measure of SRC susceptibility. The strength, elongation and impact toughness of base plate were greater in HSLA-100 steel than in HY-100 steel. The time to failure was decreased with increasing temperature and/or stress. HSLA-100 steel was more susceptible to stress relief cracking than HY-100 steel under same conditions. It is thought to be resulted from the precipitation of $\varepsilon$-Cu phase by dynamic self diffusion of solute atoms. Therefore, greater strain concentration at grain boundary of HSLA-100 steel results in the increased SRC susceptibility.y.

• 생약학회지
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• 제35권3호통권138호
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• pp.244-249
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• 2004

The effects of hesperetin and naringenin on $NF-{\kappa}B$ activation were investigated in normal rat kidney cells transformed by temperature sensitive Rous Sarcoma Virus (tsNRK). The flavonoids, naringenin and hesperetin, significantly reduced v-Src-induced $NF-{\kappa}B$ activation as well as phosphorylation of Akt and GSK-3 in tsNRK cells, whereas these compounds did not effect on platelet-derived growth factor (PDGF)-induced $NF-{\kappa}B$ activation in $NIH3T3{\gamma}l$ cells. In addition, the DNA binding activity of SP-I was also reduced but that of AP-1 was not affected by the compounds. Our study suggests that Src-induced $NF-{\kappa}B$ activation could occur via Akt-GSK-3 pathway without $IkB{\alpha}$ degradation and that naringenin and hesperetin could be used in the treatment of cancer through the inhibition of $NF-{\kappa}B$ activation.

• The Korean Journal of Physiology and Pharmacology
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• 제19권5호
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• pp.441-449
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• 2015

Flavonoids are plant pigments that have been demonstrated to exert various pharmacological effects including anti-cancer, anti-diabetic, anti-atherosclerotic, anti-bacterial, and anti-inflammatory activities. However, the molecular mechanisms in terms of exact target proteins of flavonoids are not fully elucidated yet. In this study, we aimed to evaluate the anti-inflammatory mechanism of scutellarein (SCT), a flavonoid isolated from Erigeron breviscapus, Clerodendrum phlomidis and Oroxylum indicum Vent that have been traditionally used to treat various inflammatory diseases in China and Brazil. For this purpose, a nitric oxide (NO) assay, polymerase chain reaction (PCR), nuclear fractionation, immunoblot analysis, a kinase assay, and an overexpression strategy were employed. Scutellarein significantly inhibited NO production in a dose-dependent manner and reduced the mRNA expression levels of inducible NO synthase (iNOS) and tumor necrosis factor (TNF)-${\alpha}$ in lipopolysaccharide (LPS)-activated RAW264.7 cells. In addition, SCT also dampened nuclear factor (NF)-${\kappa}B$-driven expression of a luciferase reporter gene upon transfection of a TIR-domain-containing adapter-inducing interferon-${\beta}$ (TRIF) construct into Human embryonic kidney 293 (HEK 293) cells; similarly, NF-${\kappa}B$ nuclear translocation was inhibited by SCT. Moreover, the phosphorylation levels of various upstream signaling enzymes involved in NF-${\kappa}B$ activation were decreased by SCT treatment in LPS-treated RAW264.7 cells. Finally, SCT strongly inhibited Src kinase activity and also inhibited the autophosphorylation of overexpressed Src. Therefore, our data suggest that SCT can block the inflammatory response by directly inhibiting Src kinase activity linked to NF-${\kappa}B$ activation.

• Composites Research
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• 제36권1호
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• pp.1-15
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• 2023

미래모빌리티의 발전 기대에 따라 에너지 소비 절감에 대한 수요가 증가하고 있다. 경량구조용소재는 온실가스 배출 감소 및 에너지 효율 향상을 위한 방안으로 알려져 있다. 특히, 섬유강화복합재료(FRP, fiber reinforced polymer composite)는 뛰어난 기계적 특성 및 낮은 무게로 인해 기존 합금을 대체할 수 있는 소재로 주목받는다. 본 논문에서는, 탄소섬유강화복합재료(CFRP, carbon FRP) 및 자기강화복합재료(SRC, self-reinforced composite)의 산업 적용 및 연구 동향을 강화재, 고분자 매트릭스 및 공정에 기반하여 검토하였다. 항공분야에서 주로 활용되는 에폭시 수지 기반 오토클레이브 공법의 높은 공정단가 및 긴 제조시간을 극복하기 위하여, 속경화성 에폭시 수지를 이용한 고압수지이송성형 공정으로 CFRP가 적용된 전기자동차의 양산을 보고하였다. 또한, 탄소섬유복합재료의 재활용 이슈를 해결하기 위한 열가소성 수지 기반 CFRP 및 계면 향상 방안들이 재료 및 공정 측면에서 검토되었다. FRP의 우수한 기계적 특성을 유도하는 주요한 요인으로 알려진 완벽한 매트릭스-강화재 계면을 형성하기 위하여, 고분자 섬유에 동일한 매트릭스를 함침시킨 SRC에 대한 연구들이 보고되고 있다. 다양한 열가소성 고분자에 기초한 SRC의 물리적 및 기계적 특성들을 고분자 배향 및 복합재료 구조 측면에서 검토하였다. 또한, 고연 신 폴리프로필렌 섬유 기반 SRC의 공정창 확장을 위한 공중합체 매트릭스 전략이 논의되었다. 경량구조용소재의 CFRP 및 SRC 적용은 미래모빌리티의 에너지 효율 향상에 대한 잠재적인 선택을 제공할 수 있다.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2011년도 추계학술대회
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• pp.179-180
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• 2011

본 논문은 IEEE 주최 국제대회 "2011 International Future Energy Challenge Competition (IFEC'11)"에 출품한 서울과학기술대팀의 차량탑재형 3.3kW급 배터리 충전기의 개발에 관한 것이다. 제안한 배터리 충전기의 부스트컨버터는 역률보상과 동시에 배터리의 전압 전류 제어를 수행하게 하여 절연부 SRC를 고정주파수에서 동작시킴으로서 전부하 영역에서 스위치와 다이오드의 ZCS 턴온과 턴오프가 성취되고 최적설계가 가능한 특징을 갖는다. 최대효율 94.6%(최대부하효율 92.6%), 부피 7.6L를 달성하였다.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2001년도 가을 학술발표회 논문집
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• pp.297-302
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• 2001

SRC pier at KTE 6-1 construction area is a very important structure. Precise control of quality is needed. This pier has 3.50m$\times$3.73m section and 38.20m length. So this structure must be treated as mass concrete and thermal crack caused by hydration heat should be controled. In this project belite cement concrete is used to control the thermal crack. As a result of adapting belite cement concrete perfect control is achieved. Finally, hydration heat FEM analysis of horizontal element is executed for Ordinary Portland Cement concrete and belite cement concrete. In comparison of two results, it is confirmed that using low heat portland cement concrete is necessary.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2003년도 정기총회 및 추계학술대회
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• pp.145-149
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• 2003

This study is to investigate residents' living satisfaction with high-rise mixed-use apartment complexes built in the structures of the reinforced concrete constructing and the steel framed reinforced concrete construction. The results of this study were obtained as follows: 1. Residents expressed below average satisfaction (below 3.0) with the common-area landscape and environmentally-friendly factors, children's playground and its facilities, community service for residents' by the management offices and the plan of utility. 2.According to the satisfaction of sound environment, residents of SRC group expressed above average satisfaction; it can be concluded that problems of causing noise around the residential area of the SRC and S groups were well solved in this study. However, satisfaction with the freshness of indoor air, humidity, and smell in the living quarters was rated low by the residents of SRC group. 3. High-rise mixed-use apartment complexes should accomodate families's life cycle, design an environmentally-friendly resting place in harmony with city life, and provide various communal programs for residents.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1987년도 정기총회 및 창립40주년기념 학술대회 학회본부
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• pp.530-533
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• 1987

In high-frequency switched mode converters, Series Resonant Converter (SRC) is investigated using state-plane method. Phase plane trajectories of the SRC permit a direct closed form solution of the steady state operation and can make problems easy to solve. This paper describes steady state responses and characteristics of the SRC with respect to various circuit factors. The magnitute of steady state response and the average current through load are clearly related to how such the switching frequency differs from the resonant frequency. The results of the steady state analysis can be used to estimate the device and component stress on the power circuit.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2005년도 봄학술 발표회 논문집(I)
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• pp.439-442
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• 2005

Steel encased composite columns are widely used due to their excellent structural performance in terms of stiffness, strength, and ductility. However, these columns were usually utilized for building structures and had higher steel ratio for small sections. For bridge pier applications, it is necessary to design the SRC columns having low steel ratio, which is nearly the same steel ratio as the normal RC columns. In this study, the evaluation of the composite columns with a core steel in term of the stiffness and the strength was investigated using experimental results. The effects of the steel ratio was also estimated using design provisions. The calculation of steel encased composite columns with multiple steel sections were performed and compared with RC columns.

• Steel and Composite Structures
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• 제1권2호
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• pp.201-212
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• 2001

In order to investigate the effect of the loading rate on the mechanical behavior of SRC shearwalls, we conducted the lateral loading tests on the 1/3 scale model shearwalls whose edge columns were reinforced by H-shaped steel. The specimens were subjected to the reversed cyclic lateral load under a variable axial load. The two types of loading rate, 0.01 cm/sec for the static loading and 1 cm/sec for the dynamic loading were adopted. The failure mode in all specimens was the sliding shear of the in-filled wall panel. The edge columns did not fail in shear. The initial lateral stiffness and lateral load carrying capacity of the shearwalls subjected to the dynamic loading were about 10% larger than those subjected to the static loading. The effects of the arrangement of the H-shaped steel on the lateral load carrying capacity and the lateral load-displacement hysteresis response were not significant.