• Korean Journal of Food Science and Technology
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• v.54 no.3
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• pp.288-296
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• 2022

This study aimed to verify the effect of Citrus unshiu peel water extract (CUP) on a mouse model of acute gastritis (AG) induced by HCl/ethanol. Several studies have found that CUP has anti-inflammatory effects. The AG model was induced by oral administration of 150 mM HCl/60% ethanol (550 µL) to all groups except the control group. Also, for drug treatment, sucralfate (10 mg/kg) and CUP (100 or 200 mg/kg) were orally administered for 90 minutes before induction. The effect of CUP treatment was confirmed by gross gastric mucosal damage measurement, and the levels of Glutamic Oxaloacetic Transaminase (GOT), Glutamic Pyruvic Transaminase (GPT), and myeloperoxidase were reduced as well as the levels of oxidative stress biomarkers and their related proteins. In addition, the levels of inflammatory proteins, mediators, and cytokines were significantly downregulated byPI3K/Akt signaling. Taken together, these results show that CUP treatment alleviates AG by regulating PI3K/Akt signaling.

• Journal of the Korean Geosynthetics Society
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• v.20 no.4
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• pp.43-52
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• 2021

As port development in soft ground is actively promoted for international logistics and transportation, the Deep Mixing Method (DMM) is continuously applied to form an improved column body directly in the ground by mixing cement with soil to secure the stability of the structure. However, in the case of cement, there is a problem of emitting a lot of greenhouse gases during the production process, so the development and use of new alternative materials are socially required to achieve the national goal of carbon neutrality. Accordingly, in this study, CMD-SOIL, developed to induce a hardening reaction similar to cement by recycling recycled resources, was used as a ground improvement material for the DMM. In addition, it was attempted to determine the possibility of replacing cement by conducting on-site test construction and evaluating applicability. As a result of the study, the compressive strength of CMD-SOIL compared to the design reference strength was 1.46 to 2.64 times higher in the field mixing test and 1.2 to 5.03 times higher than in the confirmed boring. In addition, the ratio (λ) of the compressive strength in the field to the design reference strength was 0.63 to 1.14, which was similar to the previous research results. Therefore, in the case of CMD-SOIL, it is possible to express the compressive strength necessary to secure stability, and there is no difference in applicability compared to existing materials such as ordinary portland cement and blast furnace slag cement, so it was analyzed that it could be used as a ground improvement material for the DMM.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.28 no.1
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• pp.15-21
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• 2022

The purpose of our study was to investigate the migration level of lead (Pb), cadmium (Cd), and barium (Ba) from glassware into a food simulant and to evaluate the exposure of each element. The test articles were glassware, including tableware, pots, and other containers. Pb, Cd, and Ba were analysed by Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES). The analytical performance of the method was validated in terms of its linearity, limit of detection (LOD), limit of quantification (LOQ), recovery, precision, and uncertainty. The monitoring was performed for 110 samples such as glass cups, containers, pots, and bottles. a food simulant. Migration test was conducted at 25? for 24 hours in a dark place using 4% acetic acid as a food simulant. Based on the data; exposure assessment was carried out to compare the estimated daily intake (EDI) to the human safety criteria. The risk levels of Pb and Ba determined in this study were approximately 1.9% and 0.3% of the provisional tolerable weekly intake (PTWI) and tolerable daily intake (TDI) value, respectively, thereby indicating a low exposure to the population.

• Journal of the Korean Recycled Construction Resources Institute
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• v.10 no.4
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• pp.457-464
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• 2022

In this study, XRF, Loss on ignition, SEM, and PSA analysis were performed on four types of fly ash in Vietnam and compared with fly ash in Korea. As a result, PC boiler fly ash in Vietnam has a similar chemical composition to that of PC boiler fly ash in Korea, where the content of SiO₂, Al₂O₃, and Fe₂O₃ accounts for about 70%. In addition, the result showed that blast furnace slags in Vietnam and Korea have similar quality criteria and performance. A binder material mixing test using four types of fly ash supplied from Vietnam was conducted, and the compressive strength ranged from 7.60 to 13.25 MPa after 28 days of curing. Vinh Tan fly ash showing the highest compressive strength was selected as the soil injection material for the chemical grouting method. For the formulation of the chemical grouting method, sodium silicate No.3 and silica-sol were used as liquid-A. As a result of measuring the gel time and the compressive strength of the homogel, they showed good performance satisfying the quality criteria applied in Korean construction fields. Therefore, Vinh Tan fly ash can be used as a soil injection material for the chemical grouting method.

• Science of Emotion and Sensibility
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• v.24 no.4
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• pp.117-128
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• 2021

In this work, we study smart gloves that can prevent carpal tunnel syndrome when using a mouse. Because the left and right wrist movements are fine, a tensile fabric sensor with a large gauge factor and low hysteresis was required before the study. A universal testing machine was used to calculate each gauge rate on four different fabrics, and the fabric with the least hysteresis was selected. In addition, three attachment methods were analyzed using Arduino to select a method with a large sensor value change. For prototypes made by attaching to the selected fabric, data patterns were analyzed using Arduino. The first method identifies only one sensor (A sensor), and the second identifies two sensors (A and B sensors). When the wrist is bent to the right, tensile fabric sensors are attached to both the left (A sensor) and right (B sensor) sides of the wrist, the A sensor is strained, increasing the △sensor value, and the B sensor is relaxed, decreasing the △sensor value. However, when the wrist was bent to the left, the pattern was analyzed in the opposite direction. Through this study, we examined smart gloves to prevent carpal tunnel syndrome with an algorithm that turns on the LED when the wrist is bent, and based on the results of this study, we will directly use mice on 10 people to identify problems and solve problems when used.

• The Korea Journal of Herbology
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• v.37 no.1
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• pp.19-29
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• 2022

Objectives : Although the pharmacological effects of anti-inflammatory and antioxidant action of Atractylodes macrocephala Koidzumi water extract (AM) have been proven from many studies, reports on the antioxidant effect of AM on ulcerative colitis (UC) are scarce. Therefore, we aimed at evaluating the anti-oxidant effect of AM on the DSS-induced UC model. Methods : To induce ulcerative colitis, 8-week-old male Balb/c mice received 5% DSS in drinking water for 1 week. After 1 week of adaptation, mice were divided into four groups (n=8 each) for use as normal (Normal), DSS Control (Control), DSS + AM 100 mg/kg (AM100)-treatment, DSS + AM 200 mg/kg (AM200)-treatment. After 1 week of the experiment, the animals were sacrificed, and the extracted colon tissue was analyzed for protein through western blot. Results : As a result of confirming the macroscopic changes in colon tissues to confirm the therapeutic effects of AM, the decrease in colon length was suppressed in the AM treatment group compared to the control group. In addition, as a result of biochemical analysis, AM administration significantly reduced serum glutamic oxalacetic transaminase, glutamic pyruvate transaminase levels and tissue malondialdehyde levels. As a result of confirming the protein expression level through western blot, AM administration significantly decreased the expression of NADPH-related proteins such as NOX2, p22^phox, and iNOS, but significantly increased the expression of SOD, catalase, and GPx-1/2. Conclusions : AM may improve DSS-induced UC in mice by modulating NADPH and antioxidant-related proteins. In conclusion, AM showed an antioxidant effect through the improvement of oxidative stress on UC.

• Journal of the Korean Geotechnical Society
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• v.26 no.7
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• pp.147-159
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• 2010

The settlement prediction is very important in preloading method for a construction site on the soft ground. At the design stage, however, it is hard to predict the settlement exactly due to limitations of the site survey. Most of the settlement prediction is performed by a regression settlement curve based on the field data during construction. In Korea, hyperbolic method has been most commonly used to align the settlement curve with the field data, because of its simplicity and many application cases. The results from hyperbolic method, however, may differ by data selections or data fitting methods. In this study, the analyses using hyperbolic method were performed about the field data of $\bigcirc\bigcirc$ site in Pusan. Two data fitting methods, using an axis transformation or an alternative method which is a direct regression method, were applied with various data groups. If data was used only after the ground water level being stabilized, fitting results using both methods were in good agreement with the measured data. Regardless of the information about the ground water level, the alternative method gives better results with the field data than the method using an axis transformation.

• The Korea Journal of Herbology
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• v.37 no.2
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• pp.1-11
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• 2022

Objectives : Although the anti-obesity effect of Schizandrae Fructus water extract has been demonstrated, its underlying mechanism is still unclear. Therefore, we aimed to evaluate the anti-obesity effect of Schizandrae Fructus water extract through the p-AMP-activated protein kinase (p-AMPK), sirtuin1 (Sirt1), and peroxisome proliferator-activated receptor-gamma coactivator 1α (PGC-1α) signaling in 60% high-fat diet (HFD)-induced obese mouse model. Methods : Male C57BL/6 mice were divided into four groups. The Normal group was fed a normal diet and the obese groups were fed 60% HFD. Except for the Control group, the GG group was supplemented with 0.5% Garcinia gummigutta and the SCW group was supplemented with 0.5% Schizandrae Fructus water extract. After 6 weeks, obesity-related biomarkers in serum were measured and the expressions of protein for lipid-related factors in liver tissue were analyzed by western blot. Results : Treatment with SCW significantly down-regulated body weight compared to the Control group. SCW down-regulated levels of triglyceride and total cholesterol in serum and significantly increased p-AMPK, Sirt1, and PGC-1α in liver tissue. In addition, the expressions of fatty acid oxidation-related proteins such as peroxisome proliferator-activated receptor α (PPARα), carnitine palmitoyltransferase 1A (CPT-1A), uncoupling protein 1 (UCP1), and uncoupling protein 3 (UCP3) were significantly up-regulated. However, fatty acid synthesis-related proteins including sterol regulatory element-binding protein-1 (SREBP-1), phospho-Acetyl-CoA Carboxylase (p-ACC), and fatty acid synthase (FAS) were significantly down-regulated. Conclusions : Taken together, SCW treatment showed anti-obesity effect by regulating both fatty acid oxidation-related and fatty acid synthesis-related proteins through AMPK/Sirt1/PGC-1α signaling in 60% HFD-induced obese mice.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.5A
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• pp.487-494
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• 2009

Friction coefficients of the prestressing tendon are the basic information required to control the prestressing force introduced to PSC structure during jacking. However, the friction coefficients show considerable differences depending on the specifications, causing much confusion to designers. In this study, the ranges of the friction coefficients presented in domestic and foreign specifications are compared together to clarify the differences. Then, a procedure is proposed that can be used to estimate the wobble and curvature friction coefficients from field data such as elongation and prestressing force and from theory related to the friction. The procedure is applied to various tendon profiles of several PSC bridges constructed by ILM, FCM and MSS. The resulting values are compared with those presented in some specifications and assumed in jacking and a reasonable range of the friction coefficient is discussed. Lift-off tests are also performed in some bridges to further verify the results. The resulting wobble friction coefficients are not as small as those presented in AASHTO specifications but range from the lower limit to mid point of domestic specifications, while the curvature friction coefficients approach or slightly exceed the upper limit.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.1B
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• pp.11-20
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• 2008

The spillway type of small and midsize dams in Korea is almost overflow weir. To examine flood control capacity of overflow spillway, FLOW-3D was applied to Daesuho dam and analysis was focused on the discharge of dam spillway by changing weir shape. Overflow phases and discharges of linear labyrinth weir and curved labyrinth weir were compared with those of existing linear ogee weir. Hydraulic model experiment was performed to verify numerical result. Verification results showed that overflow behaviors and flow characteristics in the side channel by hydraulic model experiment and numerical simulation are well matched, and water surface elevation at side wall coincides with each other. When the reservoir elevation was increased up to design flood level, in case of the linear ogee weir the flow over the crest ran through smoothly in the side channel, whereas in cases of linear labyrinth weir and curved labyrinth weirs, the flow discharge was increased by 40 cms, and the flow over the weir crest, rotating counter-clockwise, was submerged in the side channel. The results of the water level-discharge curve revealed that labyrinth weir can increase discharge by 71% compared to the discharge of linear ogee weir at low reservoir elevation since it can have longer effective length. But as water surface elevation rises, the slope of water level-discharge curve of labyrinth weir becomes milder by submergence and nappe interference in the side channel.