• Title/Summary/Keyword: SDT

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십전대보탕(十全大補湯) 와송(瓦松) 및 십전대보탕가와송(十全大補湯加瓦松)의 항암효과(抗癌效果)와 면역반응(免疫反應)에 관(關)한 연구(硏究)

  • Hwang, Gyu-Dong;Ryu, Bong-Ha;Park, Dong-Won;Ryu, Gi-Won
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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    • v.2 no.1
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    • pp.1-23
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    • 1996
  • In order to research the effects of Shipjundaebotang(SDT) and Orostachys Herba(OH) on anti-tumor and immune response, the author performed this experimental study. Experimental groups are divided into five groups, which are solid extract of Orostachys Herba by water(OHW), solid extract of Orostachys Herba by ethanol(OHE), solid extract of Shipjundaebotang (SDT), solid extract of Shipjundaebotang added by solid extract of Orostachys Herba by water(SDT+OHW) and solid extract of Shipjundaebotang added by solid extract of Orostachys Herba by ethanol (SDT+OHE). In these experimental studies, extension of survival days for anti-tumor effect was observed, and de layed type hypersensitivity and rosette forming cell for cell-mediated immune response, hemagglutinin titers and hemolysin titers for humeral immune response, spleenic natural killer cell activity and carbon clearance (K-index) in vitro were measured with mice. The result were summerized as follows: I. SDT, SDT+OHW and SDT+OHE treated groups were significantly recognized to extend the survival days of tumor bearing mice as compared with the control group. 2. Delayed type hypersensitivity was significantly increased in SDT, SDT+OHW and SDT+OHE treated groups as compared with control group. 3. Hemagglutinin titer was increasred in all sample groups as compared with control group, but not significantly. 4. Hemolysin titers was significantly increased in SDT, SDT+OHW and SDT+OHE treated groups as compared with control group, and SDT+OHE treated group showed the increasing effect with significance as compared with the other sample groups. 5. For the effect of roselle forming cell quantitation, SDT, SDT+OHW and SDT+OHE treated groups showed the increasing effect with significance as compared with control group. 6. Natural killer cell activity was significantly increased in SDT+OHW as compared with comrol group, but the other groups, except OHW and SDT+OHW treated groups, revealed the increasing effect as compared with control group, but the significance was not admitted. 7. For the effect of K-index(Carbon clearance), SDT, SDT+OHW and SDT+OHE treated groups showed the increas ing effect with significance as compared with control group. 8. The study didn't show that Orostachys herba had any significance with survival days, anti-tumor effect and immune re sponse.

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Thiadiazole-thione surfactants: Preparation, flotation performance and adsorption mechanism to malachite

  • Huang, Yaoguo;Liu, Guangyi;Liu, Jun;Yang, Xianglin;Zhang, Zhiyong
    • Journal of Industrial and Engineering Chemistry
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    • v.67
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    • pp.99-108
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    • 2018
  • In this paper, novel thiadiazole-thione surfactants including 5-heptyl-1,3,4-thiadiazole-2-thione (HpSDT), 5-phenyl-1,3,4-thiadiazole-2-thione (PSDT) and 5-(2-hydroxyphenyl)-1,3,4-thiadiazole-2-thione (HPhSDT) were synthesized and originally introduced as collectors in froth flotation. Microflotation tests showed that HpSDT exhibited better flotation response to malachite than PSDT and HPhSDT, as well as excellent flotation selectivity against quartz. The contact angle results inferred that the hydrophobization intensity of these collectors toward malachite was in the order as HpSDT> PSDT> HPhSDT. ${\zeta}$-potential recommended a chemisorption of HpSDT on malachite surfaces. FTIR deduced that cupric or cuprous atoms might bond with the S and N atoms of HpSDT to form a conjugated ring. XPS further gave an additional evidence that HpSDT-Cu(I) complexes were produced on malachite surfaces via combining surface Cu atoms with HpSDT's N and S atoms, with reducing surface Cu(II) to Cu (I). The tighter orientation arrangement on malachite and stronger hydrophobicity rendered HpSDT to possess better flotation affinity toward malachite than PSDT and HPhSDT.

Antioxidative Effect of So-Dang-Tang in Streptozotocin-Induced Diabetic Rats (Streptozotocin으로 유발 된 당뇨 흰쥐에서 소당탕(消糖湯)의 항산화 효과)

  • Jung, Jin-Ki;Park, Yong-Ki
    • Journal of Life Science
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    • v.20 no.5
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    • pp.691-696
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    • 2010
  • In this study, we investigated the antioxidative effects of So-Dang-Tang (SDT) on streptozotocin (STZ)-induced diabetic rats. Diabetes was induced by intraperitoneal injection of STZ (45 mg/kg body weight) into Sprague-Dawley rats. The SDT (200 mg/kg) and the reference drug, glibenclimide (1mg/kg), were orally administered once a day for 28 days in STZ-induced diabetic rats. The activity of antioxidant enzymes, including those of superoxide dismutase (SOD) and catalase, and the levels of glutathione (GSH) and production of malondialdehyde (MDA) were measured in the liver, kidney, and pancreas of diabetic rats. Treatment with SDT in STZ-induced diabetic rats significantly increased the activities of antioxidant enzymes and GSH levels in the liver, kidney, and pancreas when compared to those of the STZ-control group. SDT also significantly decreased lipid peroxidation product and MDA levels in STZ-induced diabetic rats. These results indicate that SDT has an antioxidative action in STZ-induced diabetic rats.

Changes of Gait Variability by the Attention Demanding Task in Elderly Adults

  • Yeo, Sang Seok
    • The Journal of Korean Physical Therapy
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    • v.29 no.6
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    • pp.303-306
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    • 2017
  • Purpose: Gait variability is defined as the intrinsic fluctuations which occur during continuous gait cycles. Increased gait variability is closely associated with increased fall risk in older adults. This study investigated the influence of attention-demanding tasks on gait variability in elderly healthy adults. Methods: We recruited 15 healthy elderly adults in this study. All participants performed two cognitive tasks: a subtraction dual-task (SDT) and working memory dual-task (WMDT) during gait plus one normal gait. Using the $LEGSys^+$ system, we measured the coefficient of variation (CV %=$100{\times}$[standard deviation/mean]) for participants' stride time, stride length, and stride velocity. Results: SDT gait showed significant increment of stride time variability compared with usual gait (p<0.05), however, stride length and velocity variability did not difference between SDT gait and usual gait (p>0.05). WMDT gait showed significant increment of stride time and velocity variability compared with usual gait (p<0.05). In addition, stride time variability during WMDT gait also significantly increased compared with SDT gait (p<0.05). Conclusion: We reported that SDT and WMDT gait can induce the increment of the gait variability in elderly adults. We assume that attention demanding task based on working memory has the most influence on the interference between cognitive and gait function. Understanding the changes during dual task gait in older ages would be helpful for physical intervention strategies and improved risk assessment.

Food quality management using sensory discrimination method based on signal detection theory and its application to drinking water (식품 품질관리를 위한 신호탐지이론(SDT) 감각차이식별분석 이론과 생수 품질관리에의 활용)

  • Kim, Min-A;Sim, Hye-Min;Lee, Hye-Seong
    • Food Science and Industry
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    • v.52 no.1
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    • pp.20-31
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    • 2019
  • Sensory perception of food/beverage products is one of the most important quality factors to determine consumer acceptability and thus sensory discrimination methodology has been a vital tool for quality management. Signal detection theory(SDT) and Thurstonian modeling provide the most advanced psychometric approach to modeling various discrimination methods. In these theories, perceptual and cognitive decisional factors are considered so that, a fundamental measure of sensory difference (d') can be computed, independent of test methods used. In this paper, sensory discrimination analysis based on SDT and Thurstonian modeling is introduced for more accurate and systematic applications of sensory and hedonic quality management in industry. Ways to realize the statistical power and relative sensitivity of sensory discrimination methods theorized in SDT and Thurstonian modeling in practice, are also discussed by using a case study of the Nongshim quality management program for drinking water in which SDT A-Not A test methodology was further optimized.

Encryption-based Image Steganography Technique for Secure Medical Image Transmission During the COVID-19 Pandemic

  • Alkhliwi, Sultan
    • International Journal of Computer Science & Network Security
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    • v.21 no.3
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    • pp.83-93
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    • 2021
  • COVID-19 poses a major risk to global health, highlighting the importance of faster and proper diagnosis. To handle the rise in the number of patients and eliminate redundant tests, healthcare information exchange and medical data are transmitted between healthcare centres. Medical data sharing helps speed up patient treatment; consequently, exchanging healthcare data is the requirement of the present era. Since healthcare professionals share data through the internet, security remains a critical challenge, which needs to be addressed. During the COVID-19 pandemic, computed tomography (CT) and X-ray images play a vital part in the diagnosis process, constituting information that needs to be shared among hospitals. Encryption and image steganography techniques can be employed to achieve secure data transmission of COVID-19 images. This study presents a new encryption with the image steganography model for secure data transmission (EIS-SDT) for COVID-19 diagnosis. The EIS-SDT model uses a multilevel discrete wavelet transform for image decomposition and Manta Ray Foraging Optimization algorithm for optimal pixel selection. The EIS-SDT method uses a double logistic chaotic map (DLCM) is employed for secret image encryption. The application of the DLCM-based encryption procedure provides an additional level of security to the image steganography technique. An extensive simulation results analysis ensures the effective performance of the EIS-SDT model and the results are investigated under several evaluation parameters. The outcome indicates that the EIS-SDT model has outperformed the existing methods considerably.

Electrochemical Properties of Nickel(II) Complexes with Multidentate N, O-Schiff Base Ligands (여러 자리 산소-질소계 시프염기 리간드 니켈(II)착물의 전기화학적 특성)

  • Kim, Sun-Deuk;Kim, Jun-Kwang;Roh, Soo-Gyun
    • Analytical Science and Technology
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    • v.10 no.4
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    • pp.246-255
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    • 1997
  • A series of Ni(II) complexes with multidentate N, O-Schiff base ligands: ie [bis-(salicylaldehyde) ethylenediamine(SED), bis-(salicylaldehyde) propylenediamine(SPD), bis-(salicylaldehyde) dietrylenetriamine(SDT), and bis-(salicylaldehyde) triethylenetetraamine(STT)] and Ni(II) complexes were synthesized. The Ni(II) complexes were characterized by elemental analysis, IR, UV-Vis and mass spectrometry. The stability constants of each nickel (II) complexes were determined by potentiometry in 70% dioxane-30% $H_2O$ and ethanol. The stability constants of Nickel(II) complexs increased in the order of Ni(II)-SPD

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The Operational Procedure on Estimating Typhoon Center Intensity using Meteorological Satellite Images in KMA

  • Park, Jeong-Hyun;Park, Jong-Seo;Kim, Baek-Min;Suh, Ae-Sook
    • Proceedings of the KSRS Conference
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    • v.1
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    • pp.278-281
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    • 2006
  • Korea Meteorological Administration(KMA) has issued the tropical storm(typhoon) warning or advisories when it was developed to tropical storm from tropical depression and a typhoon is expected to influence the Korean peninsula and adjacent seas. Typhoon information includes current typhoon position and intensity. KMA has used the Dvorak Technique to analyze the center of typhoon and it's intensity by using available geostationary satellites' images such as GMS, GOES-9 and MTSAT-1R since 2001. The Dvorak technique is so subjective that the analysis results could be variable according to analysts. To reduce the subjective errors, QuikSCAT seawind data have been used with various analysis data including sea surface temperature from geostationary meteorological satellites, polar orbit satellites, and other observation data. On the other hand, there is an advantage of using the Subjective Dvorak Technique(SDT). SDT can get information about intensity and center of typhoon by using only infrared images of geostationary meteorology satellites. However, there has been a limitation to use the SDT on operational purpose because of lack of observation and information from polar orbit satellites such as SSM/I. Therefore, KMA has established Advanced Objective Dvorak Technique(AODT) system developed by UW/CIMSS(University of Wisconsin-Madison/Cooperative Institude for Meteorological Satellite Studies) to improve current typhoon analysis technique, and the performance has been tested since 2005. We have developed statistical relationships to correct AODT CI numbers according to the SDT CI numbers that have been presumed as truths of typhoons occurred in northwestern pacific ocean by using linear, nonlinear regressions, and neural network principal component analysis. In conclusion, the neural network nonlinear principal component analysis has fitted best to the SDT, and shown Root Mean Square Error(RMSE) 0.42 and coefficient of determination($R^2$) 0.91 by using MTSAT-1R satellite images of 2005. KMA has operated typhoon intensity analysis using SDT and AODT since 2006 and keep trying to correct CI numbers.

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Electrochemical Properties of Copper(II) Complexes with Multidentate N,O-Schiff Base Ligands (여러 자리 산소-질소계 시프염기 리간드 구리(II) 착물의 전기화학적 특성)

  • Kim, Sun-Deuk;Jang, Gi-Ho;Kim, Jun-Kwang;Lee, Seong-Woo;Joung, Jae-Joung
    • Analytical Science and Technology
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    • v.9 no.4
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    • pp.345-354
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    • 1996
  • Algal(II) Multidentate N, O-Schiff base ligands, such as bis(salicylaldehyde) ethylenediimine(SED), bis(salicylaldehyde) propylenediimine(SPD), bis(salicylaldehyde) diethylenetriimine(SDT), bis (salicylaldehyde) triethylenetetraimine(STT) and bis(salicyl-aldehyde)tetraethylenepentaimine(STP) were prepared. Stepwise proton dissociation constants of the Schiff base were measured potentiometrically in ethanol and a mixture of 70% dioxane and 30% $H_2O$. The stability constants of copper(II)-Schiff base complexes were in the order of Cu(II)-SPD${\leq}$Cu(II)-SED~STT${\leq}$Cu(II)-STP. Oxidation-reduction process of the Cu(II)-Schiff base complexes was involved with one-electron reaction.

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