• 제목/요약/키워드: SCN.

검색결과 166건 처리시간 0.022초

Neurobiological Functions of the Period Circadian Clock 2 Gene, Per2

  • Kim, Mikyung;Pena, June Bryan de la;Cheong, Jae Hoon;Kim, Hee Jin
    • Biomolecules & Therapeutics
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    • 제26권4호
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    • pp.358-367
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    • 2018
  • Most organisms have adapted to a circadian rhythm that follows a roughly 24-hour cycle, which is modulated by both internal (clock-related genes) and external (environment) factors. In such organisms, the central nervous system (CNS) is influenced by the circadian rhythm of individual cells. Furthermore, the period circadian clock 2 (Per2) gene is an important component of the circadian clock, which modulates the circadian rhythm. Per2 is mainly expressed in the suprachiasmatic nucleus (SCN) of the hypothalamus as well as other brain areas, including the midbrain and forebrain. This indicates that Per2 may affect various neurobiological activities such as sleeping, depression, and addiction. In this review, we focus on the neurobiological functions of Per2, which could help to better understand its roles in the CNS.

The Succinate : Quinone Oxidoreductase of Marine Bacterium Vibiro alginolyticus is a $H^+$

  • Kim, Young-Jae
    • Journal of Microbiology and Biotechnology
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    • 제10권1호
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    • pp.48-50
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    • 2000
  • The energetics at the succinate:quinone oxidoreductase segment of V. alginolyticus was studied using a fluorescence quenching technique with inside-out membrane vesicles. A transient generation of the membrane potential (inside-positive) and ${\Delta}pH$ (inside-acidic) occurred in the presence of KCN and succinate when ubiquinone-1 (Q1) was added. The membrane potential (\Delta\psi$) generated by the succinate; quinone oxidoreductase segment was completely collapsed by the protonophore carbonylcyanide m-chlorophenylhydrazone (CCCP) and the membrane permeable anion $SCN^{-}$, whereas the ${\Delta}pH$ was completely collapsed by CCCP and $(NH_4)_2SO_4$. From these results, it was concluded that the succinate: quinone oxidoreductase segment as well as quinol oxidase [1] in the respiratory chain of V. alginolyticus generated $H^{+}$ electrochemical potential.

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活性炭에 依한 Hg(II) 이온의 吸着에 관한 조사연구(1) (A Study on the Adsorption of Hg(II) Ion by Activated Carbon(1))

  • Lee, Hyun;Lee, Jong-Hang;Yun, O. Sub
    • 한국환경보건학회지
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    • 제14권2호
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    • pp.65-71
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    • 1988
  • In this study, the method of adsorption by activated carbon in the removal of Hg(II) ion in waste water was treated. The influence of kinds of activated carbon and effect of temperature and the influence of coexistent salt on adsorption rates, the influence of pH in the adsorption, equilibrium and adsorption of mercury from activated carbon were investigated. From the adsorption on activated carbon of mercury(II) ion in the presence of cyanide or thiocyanate ion was found that mercury(II) was easily adsorved onto the activated carbon in the form of complex artion such as Hg(CN)$_4^{2-}$, Hg(SCN)$_4^{2-}$ respectively. ZnCl$_2$ activation method had a higher adsorptive ability than steam activation method in adsorption of Hg on activated carbon. Activated carbon adsorbed iodide ion is very effective on adsorption of Hg.

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실내이미지 유형별 모델 개발에 관한 연구 (A Study on the Models Corresponding to Interior Image Types)

  • 방희조;박영순
    • 한국실내디자인학회:학술대회논문집
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    • 한국실내디자인학회 1999년도 춘계학술발표대회 논문집
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    • pp.94-97
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    • 1999
  • The purpose of this study was to prepare the visual communication tool, which would be used for the interior design consulation to reduce the communication gap between an interior designer and a client. To achieve the study purpose, review of literature, questionnaire survey, qualitative analysis and design research methods were used. The major results of this study were as follows: 1) "Image Cube" was designed as a comprehensive rule to classify interior image types. By this, eight interior image types were classified: SFU(Simple-Formal-Urbane), SFN(Simple-Formal-Natural), SCU(Simple-Casual-Urbane), SCN(Simple-Casual-Natural), DFU(Decorative-Formal-Urbane), DFN(Decorative-Formal-Natural), DCU(Decorative-Casual-Urbane), DCN(Decorative-Casual-Natural). 2) The Interior image collages were composed to present the overall feeling of each interior image type. 3) The Interior image models which would be used as the standard to be modified to various sub-types through the interior design consultation were produced corresponding to interior image types.age types.

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황산크롬(III) 착화합물 수용액으로부터의 크롬전착 (Electrodeposition of Chromium from Chromiun(III) Sulfate Complexes in Aqueous Solutions)

  • 고석수;송진태
    • 한국표면공학회지
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    • 제21권4호
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    • pp.149-159
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    • 1988
  • Electrodeposition of chromium from low concentration chromjum (III) sulfate complexess in aqueous using sodium formate-glycine mixtures as a complexing agent was studied. In the bath formation, it is found that the optimum again temperature and time for equilibration of the electrolytes are nrcessary for 24 hrs at 45$^{\circ}C$and the optimum elecrical charge for low current electrolysis which might be produced Cr(II) ions in the electrolytes is necessary for minum 2Ah/$\ell$. The optmun concentration off standard electrolyte for main composition is 0.05M chromium(III) sulfate, 0.2M sodium formate-0.2M glycine, and I mMNaSCN as a catalysea, respectivwly. The standard electrolyte is shows good covering, good throwing power, and 6% of current efficiency (Cr(III)basis). The oppearance of electrodeposits shows att active bright chromium. The SEM morphology of the chromjum coating is observed as smooth surfaces and dispersed micro prcro pores. X-ray diffraction analysis shows a bcc structure which the perferred orintation of the chromium electrodeposits is strongin(200)plane.

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황산크륨(III) 착화합물 스용액으로부터의 크롬전착반응의 전기화학적 거동 (Electrochemical Behaviors of Chromium Electrodeposition from Chromium(III) Sulfate complexes Aqueous Solutions)

  • 고석수;송진태
    • 한국표면공학회지
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    • 제21권4호
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    • pp.160-167
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    • 1988
  • Electrochemical behaviors od chromium electrodeposition from 0.05M chromium (III) sulface complexes in aqueous solutions using sodium formate-glycine mixtures as a complexing agent were studied. In the cathodic current-potential cures, it is found that the intial limiting current of Cr(III) is proportional to square root of scan rate and activiation energy from Arrhenius plot is s obtained 3.05Kcal/mol. From this results, the reaction is considered, Cr3++e longrightarrow Cr2+, which is controlled diffusion of Cr (III). It is also found that the chromium is deposited when the potential reaches to hydrogen evolution potential. Effects of NaSCN as a catalyser in the electrolyte were investigated NCS- anion seems to react strongly by specific absorption at the inner HelmholtZ layer, so that, it is considered to suppress the electrodeposition reaction reaction for chromjum, and also it is considered multipe-bridge such as Cr(III)-NCS---M(M;cathode).

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무기 첨가제에 대한 PCB제조용 무전해 동도금액의 영향 (Effects of Inorganic Additives on Electroless Copper Plation Bath for PCB)

  • 이홍기;이주성
    • 한국재료학회지
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    • 제4권2호
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    • pp.187-193
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    • 1994
  • 무전해 동도금액에서의 각종 안정제, 촉진제등의 첨가제에 따른 영향을 고찰하였다. 욕의 기본성분은 황산구리 10g/1, EDTA-2Na 40g/1, 포르말린 3ml/1, pH조절용 수산화나트륨 용액으로 조성하였고, 안정제, 도금촉진제 및 계면활성제의 첨가에 따른 분극곡선을 검토하여 도금욕의 경향을 검토한뒤 농도변화에 따른 도금속도를 측정하여 최적조건을 구하였다. 안정제는 $\alpha$, $\alpha$'-dipyridy1과 NaSCN을 혼합 사용하는 것이 좋았으며 촉진제로는 pyridine이 계면활성제로는 PEG 4000이 좋았다. 첨가량은 5mg/1이하의 미량이었으며 이후 첨가량이 증가함에 따라 증가함에 따라 도금속도는 직선적으로 감소하였다.

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가교폴리(4-비닐피리딘)과 산성염료와의 결합에 대한 특이한 온도의존성 - 무기전해질의 효과 - (Peculiar Temperature Dependence on the Binding of Acid Dye by Crosslinked Poly(4-vinylpyridine) -The Effect of Inorganic Electrolytes-)

  • Lee, Suk Kee
    • 한국염색가공학회지
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    • 제9권2호
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    • pp.25-31
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    • 1997
  • The extent of binding of acid dye (methyl orange) by crosslinked poly-(4-vinylpyridine) (CHP4VP) has been investigated in aqueous solution containing of inorganic electrolytes such as NaCl and NaSCN. It was found that the first binding constants ($K_{1}$) in the presence of the salts were smaller than those in the absence of the salts and the values of $K_{1}$ showed a bell-shaped curve against temperature. These results are discussed in terms of both the competition binding between the dye and salt anions for the crosslinked polymer and the change of hole size of CHP4VP with the addition of the salts.

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멜라토닌의 기능성 및 유제품 활용 (The Potential of Melatonin for the Application in Dairy Products)

  • 송민유;박원서;유자연;함준상
    • Journal of Dairy Science and Biotechnology
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    • 제36권1호
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    • pp.14-25
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    • 2018
  • Melatonin, an indolic tryptophan-derived compound, is secreted rhythmically from the pineal gland, mainly under the regulation of the circadian clock located in the suprachiasmatic nuclei (SCN) of the hypothalamus. Melatonin is widely present in nature, with biological activities in unicellular organisms, plants, and animals. A major function of melatonin is to transmit information to organisms about certain physiological functions in response to daily and seasonal variations in their environment. In this paper, we review a variety of melatonin's functional properties, its occurrence in plants, and its synthesis by yeasts. Fermented milk supplemented with melatonin-rich plants and yeasts can be used for the effective treatment of sleep disorders.

Metalloporphyrin-Catalyzed Chemoselective Oxidation of Sulfides with Polyvinylpyrrolidone-Supported Hydrogen Peroxide: Simple Catalytic System for Selective Oxidation of Sulfides to Sulfoxides

  • Zakavi, Saeed;Abasi, Azam;Pourali, Ali Reza;Talebzadeh, Sadegh
    • Bulletin of the Korean Chemical Society
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    • 제33권1호
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    • pp.35-38
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    • 2012
  • Room temperature oxidation of organic sulfides with polyvinylpyrrolidone-supported hydrogen peroxide (PVP-$H_2O_2$) in the presence of Mn(III) complexes of meso-tetraphenylporphyrin, Mn(TPP)X (X = OCN, SCN, OAc, Cl) and imidazole (ImH) leads to the highly chemoselective (ca. 90%) oxidation of sulfides to the corresponding sulfoxide. The efficiency of reaction has been shown to be influenced by different reaction parameters such as the nature of counterion (X) and solvent as well as the molar ratio of reactants. Using Mn(TPP)OCN and ImH in 1:15 molar ratio and acetone as the solvent leads to the efficient oxidation of different sulfides.