• 융합보안논문지
• /
• 제20권3호
• /
• pp.99-108
• /
• 2020

신종 코로나 바이러스(SARS-CoV-2)로 인한 팬데믹이 확산되는 추세로 단기간 내 종식을 기대하기 힘든 상황이다. 디지털 기술의 활용은 코로나19 억제에 대해 가시적인 성과를 보여주고 있지만, 개인정보호호 측면에서는 논란이 되고 있다. 본 논문에서는 코로나19 팬데믹에 대한 우리나라 및 각국의 대응 현황을 살펴보고, 디지털 도구를 활용하되 개인정보를 보호하는 방향에 대해 제언한다. 팬데믹 억제를 위해서는 데이터 수집 및 처리가 필수적이지만 개인정보보호를 고려하여 꼭 필요한 수준과 범위로 제한해야 하고, 국제적 규모의 협력과 한시적이고 투명한 개인정보 이용, 이를 위한 법적·제도적 기반 확립이 필요하다. 오늘날 이 같은 데이터와 알고리즘 활용은 지속적으로 증가할 것이므로, 이와 더불어 개인정보보호를 위한 기술·제도적 보완 노력이 계속되어야 한다.

• 대한간호학회지
• /
• 제51권5호
• /
• pp.511-524
• /
• 2021

The coronavirus disease 2019 (COVID-19) has emerged as a threat to human health and public safety. People of all ages are susceptible to severe acute respiratory syndrome coronavirus 2 infection. However, the clinical manifestations of this infection differ by age. This study purposes to describe healthcare considerations for special populations, such as children, pregnant and lactating women, and older adults, who may have unique healthcare needs, in the pandemic situation. To realize the research purpose, we conducted a review of the practice guidelines of public documents and qualified studies that were published online/offline during a specific period. The review identified current knowledge on care for newborns, children in schools, pregnant women (from antenatal to postpartum care), and older adults suffering from high-risk conditions. Subsequently, we summarize vaccination guidance for special populations and, finally, discuss the issues currently affecting special populations. Therefore, this current knowledge on care for special populations helps nurses to provide accurate information on vaccinations aimed at preventing COVID-19 and protecting the masses from infection. Currently, the scarcity of information on COVID-19 variants necessitates further research on measures to reduce pandemic spread.

• 대한약침학회지
• /
• 제24권4호
• /
• pp.165-172
• /
• 2021

The COVID-19, the most infectious pandemic disease arising due to SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) has caused huge issues globally. In this review, we discuss the impact of COVID-19 on the immune system of the human body and the protective mechanisms of the host immune system opposing viral infections. Here, we summarize the effect of the pandemic of the novel coronavirus disease on the immune system such as sleep and Behavioral Immune System (BIS) together with consideration of researcher's observation points of view. We draw particular attention to recent up-to-date reports concerning COVID-19 drugs as well as information about the landscape document for COVID-19 vaccines released by WHO (World Health Organization), and some adverse events of COVID-19 vaccination. Additionally, can take part in the preventive appraise in opposition within this pandemic severe COVID-19 infections disease may affect some outcome in physical exercise, physical movement, healthy diets, and good nutrition are significant for supporting the immune systems and summarize AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) Indian medicinal systems guidelines for immunity boosting procedures during COVID-19 pandemic.

• Journal of Ginseng Research
• /
• 제46권3호
• /
• pp.321-330
• /
• 2022

Coronavirus has been spreading rapidly around the world since it broke out in China in 2019. Respiratory diseases caused by coronavirus infection cause various diseases ranging from asymptomatic subclinical infections to severe pneumonia and cardiovascular complications, leading to death. In this regard, natural products are being studied to prevent various diseases caused by COVID-19. In current review, we would like to present mechanisms related to the inhibition of heart disease in ginseng and ginsenoside against SARS-CoV-2. In many previous studies, ginseng and ginsenoside are known to have antioxidant, blood flow improvement, improvement of vascular and heart function, blood pressure control, suppression of myocardial infarction and heart failure, and antiarrhythmia. Therefore, ginseng and ginsenoside have a possibility to suppress cardiovascular complications caused by COVID-19. Many of research provide evidence for ginseng and ginsenoside as treatments for the risk of cardiovascular complications. However, in this review, more specific contents on the proposition of the efficacy of ginseng and ginsenoside for COVID-19 should be presented. Therefore, we hope that researches to reduce cardiovascular complications of ginseng and ginsenoside for COVID-19 should be presented to reduce mortality for COVID-19.

• 대한후두음성언어의학회지
• /
• 제33권1호
• /
• pp.54-57
• /
• 2022

The coronavirus disease (COVID-19) by severe acute syndrome coronavirus-2 (SARS-CoV-2) occurs the unprecedented pandemic during recent two years and the WHO declared a global pandemic of COVID-19 in March 2020. The most common sampling sites in COVID-19 test are the oropharynx and nasopharynx. We recently encountered a total laryngectomee who had a positivity COVID-19 diagnostic test from the tracheostoma, on the other hand, false negativity from the nasal cavity. The meaning of this case is that accurate screening test could be achieved by performing a test through the tracheostoma as well as nasal cavity or oropharynx. We also would like to discuss the accurate testing methods of patients whose airflow has distorted due to surgery, the management method of these patients, and the need of further research in the COVID-19 pandemic period with relevant literature reviews.

• Molecules and Cells
• /
• 제44권12호
• /
• pp.861-878
• /
• 2021

The human genome contains many retroviral elements called human endogenous retroviruses (HERVs), resulting from the integration of retroviruses throughout evolution. HERVs once were considered inactive junk because they are not replication-competent, primarily localized in the heterochromatin, and silenced by methylation. But HERVs are now clearly shown to actively regulate gene expression in various physiological and pathological conditions such as developmental processes, immune regulation, cancers, autoimmune diseases, and neurological disorders. Recent studies report that HERVs are activated in patients suffering from coronavirus disease 2019 (COVID-19), the current pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection. In this review, we describe internal and external factors that influence HERV activities. We also present evidence showing the gene regulatory activity of HERV LTRs (long terminal repeats) in model organisms such as mice, rats, zebrafish, and invertebrate models of worms and flies. Finally, we discuss several molecular and cellular pathways involving various transcription factors and receptors, through which HERVs affect downstream cellular and physiological events such as epigenetic modifications, calcium influx, protein phosphorylation, and cytokine release. Understanding how HERVs participate in various physiological and pathological processes will help develop a strategy to generate effective therapeutic approaches targeting HERVs.

• Genomics & Informatics
• /
• 제18권3호
• /
• pp.31.1-31.8
• /
• 2020

The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. No specific therapeutic agents or vaccines for COVID-19 are available, though several antiviral drugs, are under investigation as treatment agents for COVID-19. The use of convalescent plasma transfusion that contain neutralizing antibodies for COVID-19 has become the major focus. This requires mass screening of populations for these antibodies. While several countries started reporting population based antibody rate, its simple point estimate may be misinterpreted without proper estimation of standard error and confidence intervals. In this paper, we review the importance of antibody studies and present the 95% confidence intervals COVID-19 antibody rate for the Korean population using two recently performed antibody tests in Korea. Due to the sparsity of data, the estimation of confidence interval is a big challenge. Thus, we consider several confidence intervals using Asymptotic, Exact and Bayesian estimation methods. In this article, we found that the Wald method gives the narrowest interval among all Asymptotic methods whereas mid p-value gives the narrowest among all Exact methods and Jeffrey's method gives the narrowest from Bayesian method. The most conservative 95% confidence interval estimation shows that as of 00:00 on September 15, 2020, at least 32,602 people were infected but not confirmed in Korea.

• International Journal of Computer Science & Network Security
• /
• 제22권9호
• /
• pp.149-158
• /
• 2022

The pandemic of Covid-19 (Coronavirus Disease 19) has devastated the world, affected millions of people, and disrupted the world economy. The cause of the Covid19 epidemic has been identified as a new variant known as Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV2). It motives irritation of a small air sac referred to as the alveoli. The alveoli make up most of the tissue in the lungs and fill the sac with mucus. Most human beings with Covid19 usually do no longer improve pneumonia. However, chest x-rays of seriously unwell sufferers can be a useful device for medical doctors in diagnosing Covid19-both CT and X-ray exhibit usual patterns of frosted glass (GGO) and consolidation. The introduction of deep getting to know and brand new imaging helps radiologists and medical practitioners discover these unnatural patterns and pick out Covid19-infected chest x-rays. This venture makes use of a new deep studying structure proposed to diagnose Covid19 by the use of chest X-rays. The suggested model in this work aims to predict and forecast the patients at risk and identify the primary COVID-19 risk variables

• Nonlinear Functional Analysis and Applications
• /
• 제28권2호
• /
• pp.497-520
• /
• 2023

Numerous problems in science and engineering defined by nonlinear functional equations can be solved by reducing them to an equivalent fixed point problem. Fixed point theory provides essential tools for solving problems arising in various branches of mathematical analysis, such as split feasibility problems, variational inequality problems, nonlinear optimization problems, equilibrium problems, complementarity problems, selection and matching problems, and problems of proving the existence of solution of integral and differential equations.The theory of fixed is known to find its applications in many fields of science and technology. For instance, the whole world has been profoundly impacted by the novel Coronavirus since 2019 and it is imperative to depict the spread of the coronavirus. Panda et al. [24] applied fractional derivatives to improve the 2019-nCoV/SARS-CoV-2 models, and by means of fixed point theory, existence and uniqueness of solutions of the models were proved. For more information on applications of fixed point theory to real life problems, authors should (see [6, 13, 24] and the references contained in).

• 대한영상의학회지
• /
• 제83권2호
• /
• pp.378-386
• /
• 2022

Coronavirus disease 2019 (이하 COVID-19)의 대유행이 지속됨에 따라 COVID-19 감염에서 회복된 환자들의 후유증과 치료에 많은 관심이 발생하고 있다. COVID-19의 장기적인 후유증은 아직 알려지지 않았지만, 최근 발표된 문헌에 따르면 일부 환자들은 퇴원 후에도 증상이 지속되며 영상의학적 이상 소견을 보였다. 우리는 COVID-19 회복 후에 지속적인 호흡곤란이 있던 네 명의 환자들 증례에서 폐 섬유화 또는 기질화 폐렴 패턴을 나타내는 폐 후유증을 보고하고자 한다.