• Title/Summary/Keyword: SAE

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Inter-Domain Mobility Management Based on the Proxy Mobile IP in Mobile Networks

  • Gohar, Moneeb;Koh, Seok-Joo
    • Journal of Information Processing Systems
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    • v.12 no.2
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    • pp.196-213
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    • 2016
  • System Architecture Evolution (SAE) with Long Term Evolution (LTE) has been used as the key technology for the next generation mobile networks. To support mobility in the LTE/SAE-based mobile networks, the Proxy Mobile IPv6 (PMIP), in which the Mobile Access Gateway (MAG) of the PMIP is deployed at the Serving Gateway (S-GW) of LTE/SAE and the Local Mobility Anchor (LMA) of PMIP is employed at the PDN Gateway (P-GW) of LTE/SAE, is being considered. In the meantime, the Host Identity Protocol (HIP) and the Locator Identifier Separation Protocol (LISP) have recently been proposed with the identifier-locator separation principle, and they can be used for mobility management over the global-scale networks. In this paper, we discuss how to provide the inter-domain mobility management over PMIP-based LTE/SAE networks by investigating three possible scenarios: mobile IP with PMIP (denoted by MIP-PMIP-LTE/SAE), HIP with PMIP (denoted by HIP-PMIP-LTE/SAE), and LISP with PMIP (denoted by LISP-PMIP-LTE/SAE). For performance analysis of the candidate inter-domain mobility management schemes, we analyzed the traffic overhead at a central agent and the total transmission delay required for control and data packet delivery. From the numerical results, we can see that HIP-PMIP-LTE/SAE and LISP-PMIP-LTE/SAE are preferred to MIP-PMIP-LTE/SAE in terms of traffic overhead; whereas, LISP-PMIP-LTE/SAE is preferred to HIP-PMIP-LTE/SAE and MIP-PMIP-LTE/SAE in the viewpoint of total transmission delay.

Effect of Sauropus Androgynus (Katuk) Extract on Egg Production and Lipid Metabolism in Layers

  • Santoso, U.;Setianto, J.;Suteky, T.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.3
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    • pp.364-369
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    • 2005
  • The present study was conducted to evaluate effect of Sauropus androgynus extract (SAE) on egg production and lipid metabolism in layer chickens. Forty-eight layers aged 42 weeks (strain RIR) were distributed to 6 treatment groups as follows. One group was fed diet without SAE as the control ($P_0$), and other five groups were fed diet plus hot water-extracted SAE at level of 9 g/kg diet ($W_9$), diet plus ethanol extracted SAE at level of 0.9 g/kg diet ($E_{0.9}$), diet plus ethanol extracted SAE at level of 1.8 g/kg ($E_{1.8}$), diet plus methanol extracted SAE at level of 0.9 g/kg ($M_{0.9}$), and diet plus methanol extracted SAE at level of 1.8 g/kg ($M_{1.8}$). It was shown that SAE inclusion significantly increased egg production (p<0.05). Methanol-extracted SAE groups had lower egg production than ethanol-extracted SAE group (p<0.05). SAE supplemented groups had better feed conversion efficiency than the unsupplemented group (p<0.05). It was shown that ethanol extracted SAE resulted in the lowest feed conversion efficiency among the SAE supplemented groups (p<0.05). SAE supplementation significantly reduced abdominal fat, gizzard surrounded fat, liver fat (p<0.05), serum triglyceride, total cholesterol, VLDL+LDL-c (p<0.01), atherogenic index (p<0.05), egg cholesterol and triglyceride (p<0.05), but it had no effect on mesenteric fat, sartorial fat and fatty liver score. In conclusion, SAE supplementation could increase egg production but reduced egg cholesterol.

Sanghuangporus sanghuang extract inhibits the proliferation and invasion of lung cancer cells in vitro and in vivo

  • Weike Wang;Jiling Song;Na Lu;Jing Yan;Guanping Chen
    • Nutrition Research and Practice
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    • v.17 no.6
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    • pp.1070-1083
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    • 2023
  • BACKGROUND/OBJECTIVES: Sanghuangporus sanghuang (SS) has various medicinal effects, including anti-inflammation and anticancer activities. Despite the extensive research on SS, its molecular mechanisms of action on lung cancer are unclear. This study examined the impact of an SS alcohol extract (SAE) on lung cancer using in vitro and in vivo models. MATERIALS/METHODS: Different concentrations of SAE were used to culture lung cancer cells (A549 and H1650). A cell counting kit-8 assay was used to detect the survival ability of A549 and H1650 cells. A scratch assay and transwell cell invasion assay were used to detect the migration rate and invasive ability of SAE. Western blot analysis was used to detect the expression of B-cell lymphoma-2 (Bcl-2), Bcl2-associated X (Bax), cyclin D1, cyclin-dependent kinases 4 (CDK4), signal transducer and activator of transcription 3 (STAT3), and phosphorylated STAT3 (p-STAT3). Lung cancer xenograft mice were used to detect the inhibiting ability of SAE in vivo. Hematoxylin and eosin staining and immunohistochemistry were used to detect the effect of SAE on the structural changes to the tumor and the expression of Bcl-2, Bax, cyclin D1, CDK4, STAT3, and p-STAT3 in lung cancer xenograft mice. RESULTS: SAE could inhibit lung cancer proliferation significantly in vitro and in vivo without cytotoxicity. SAE suppressed the viability, migration, and invasion of lung cancer cells in a dose and time-dependent manner. The SAE treatment significantly decreased the proapoptotic Bcl-2/Bax ratio and the expression of pro-proliferative proteins Cyclin D1 and CDK4 in vitro and in vivo. Furthermore, SAE also inhibited STAT3 expression. CONCLUSIONS: SAE reduced the cell viability and suppressed cell migration and invasion in human lung cancer cells. Moreover, SAE also exhibited anti-proliferation effects in vivo. Therefore, SAE may have benefits in cancer therapy.

Overview of SAE/LTE security

  • Prasad, Anand R.;Zhang, Xiaowei
    • IEIE Transactions on Smart Processing and Computing
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    • v.2 no.1
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    • pp.36-43
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    • 2013
  • This paper provides an overview of the security in the System Architecture Evolution (SAE) / Long-Term Evolution (LTE) system. Security is an integral part of SAE/LTE with improvements over the Third Generation (3G) system. This paper reviews the SAE/LTE system architecture, and discusses the security requirements, algorithms, Authentication and Key Agreement (AKA), Security Mode Command (SMC), key hierarchy and security for mobility.

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Distributed Mobility Management Scheme in LTE/SAE Networks (LTE/SAE 네트워크에서 분산 이동성 관리 기법)

  • Kim, Yong-Hwan;Han, Youn-Hee;Kim, Min;Park, Seok Yong;Moon, Sang Jun;Lee, Jin Ho;Choi, Dae Kyu
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38B no.11
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    • pp.879-894
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    • 2013
  • Recently, due to a explosive growth in the mobile Internet traffic, the problem of excessive data traffic handling on core network and thus scalability problem have been magnified in 3GPP LTE/SAE networks. Current LTE/SAE network based on the central P-GW (PDN Gateway) used as mobility anchor cannot deal with such demand for exponentially increasing mobile Internet traffic. In this paper, we propose a new LTE/SAE network architecture supporting distributed P-GWs and corresponding distributed mobility management to solve these problems. For this, in addition to the deployment of such distributed P-GWs, we propose a dynamic and distributed mobility management by distributing MMEs (Mobility Management Entities) which dynamically manages the location information of a UE's PDN connection, and also propose a handover procedure of such PDN connections by using the proposed distributed P-GWs and MMEs. The performance of the proposed dynamic and distributed LTE/SAE network system is compared with the current LTE/SAE network system in terms of handover latency and network throughput.

Evaluation of Deformation Capacity of Various Steel Springs Subjected to Tensile Loading or Uniaxial Cyclic Loading (인장하중 및 반복하중을 받는 강재 스프링의 변형 성능 평가)

  • Kwon, Hee-Yong;Hwang, Seung-Hyeon;Yang, Keun-Hyeok;Kim, Sanghee;Choi, Yong-Soo
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.4
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    • pp.1-10
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    • 2022
  • In this study, to evaluate the possibility of using a steel spring as a displacement-dependent damping device, tensile loading and cyclic loading tests were performed. The main experimental variables were the type of steel (SAE9254 and SS275), the spring constant (700 N/mm, 1,000 N/mm, and 1,400 N/mm), and the presence or absence of heat treatment for SAE9254. As a result of the tensile test, the ratios of the measured spring constant to the design spring constant of the steel springs made with SAE9254 ranged from 1.08 to 1.13, while the ratios of the design spring constant and the measured spring constant of the steel springs made with SS275 ranged from 0.86 to 0.97. After yielding, the slope values of the load-displacement curve of the SAE9254 with/without heat treatment were about 240~251 N/mm and 92 N/mm, respectively, but the slope values of the load-displacement response of SS275 were almost zero. According to the uniaxial cyclic loading test results, all specimens were satisfied with three conditions for a displacement-dependent damping device in KDS 41 17 00 (2019): the maximum force and minimum force at zero displacement, the maximum force and minimum force at the maximum displacement, and the energy dissipation capacity. In addition, the equivalent damping ratios of steel springs made with SAE9254(non-heat treatment) and SS275 were approximately 2.8 times and 1.9 times greater, respectively, than that of steel springs made with SAE9254.