• Journal of the Optical Society of Korea
• /
• v.19 no.4
• /
• pp.403-408
• /
• 2015

To evaluate the effects of spherical aberration (SA) correction on optical quality in pseudophakic eyes, we simulated the optical quality of the human eye by computation of the modulation transfer function (MTF). We reviewed the medical records of patients who underwent cataract surgery in Asan Medical Center, retrospectively. A Zywave aberrometer was used to measure optical aberrations at 1-12 postoperative months in patients with AR40e intraocular lens implants. The MTF was calculated for a 5 mm pupil from measured wavefront aberrations. The area under the MTF curve (aMTF) was analyzed and the maximal aMTF was calculated while changing the SA ($-0.2{\sim}+0.2{\mu}m$) and the defocus (-2.0 ~ +2.0 D). Sixty-four eyes in 51 patients were examined. The maximal aMTF was $6.61{\pm}2.16$ at a defocus of $-0.25{\pm}0.66D$ with innate SA, and $7.64{\pm}2.63$ at a defocus of $0.08{\pm}0.53D$ when the SA was 0 (full correction of SA). With full SA correction, the aMTF increased in 47 eyes (73.4%; Group 1) and decreased in 17 eyes (26.6%; Group 2). There were statistically significant differences in Z(3, -1) (vertical coma; P = 0.01) and Z(4, 4) (tetrafoil; P = 0.04) between the groups. The maximal aMTF was obtained at an SA of $+0.01{\mu}m$ in Group 1 and an SA of $+0.13{\mu}m$ in Group 2. Optical quality can be improved by full correction of SA in most pseudophakic eyes. However, residual SA might provide benefits in eyes with significant radially asymmetric aberrations.

• Food Science of Animal Resources
• /
• v.30 no.1
• /
• pp.66-72
• /
• 2010

Pediococcus pentosaceus SA131 was isolated from jeotgal, is the bacteriocin producer against bovine mastitis pathogens, Streptococcus uberis E290, Enterococcus gallinarum E362, and Staphylococcus epidermidis ATCC 12228. The medium composition for pediocin SA131 production by P. pentosaceus SA131 was optimized using response surface methodology. Component of medium was studied as carbon source (glucose, fructose, lactose, glycerol, sucrose, maltose, and mannitol), nitrogen source (beef extract, yeast extract, peptone, malt extract, and tryptone), mineral and surfactant ($MgSO_4$, $KH_2PO_4$, $(NH_4)_2SO_4$, $MnSO_4$, NaCl, sodium acetate, and Tween 80). Through one factor-at-a-time experiment, glucose, fructose, yeast extract, malt extract, NaCl, $MgSO_4$, and Tween 80 were determined as the good ingredient. The effects of major factors for pediocin SA131 production were investigated by two-level fractional factorial designs (FFD). By a $2^4$ FFD, fructose, yeast extract, and $MnSO_4$ were found to be the important factors for the bacteriocin production. Subsequently, a $2^3$ central composite design (CCD) was adopted to derive a statistical model for optimizing the composition of the fermentation medium. The estimated optimum composition for the production of pediocin SA131 by P. pentosaceus SA131 was as follows; 0.13% fructose, 1% glucose, 1.8% yeast extract, 2.58% $MnSO_4$, 0.2% NaCl, and 0.2% Tween 80. The pediocin production under optimized medium was increased to 1,000 AU/mL, compared to the 400 AU/mL in MRS medium.

• Korean Journal of Poultry Science
• /
• v.37 no.3
• /
• pp.215-219
• /
• 2010

The applicability of electronic nose was tested to detect lipid peroxidation in chickens and to measure antioxidant effect of astaxanthin in chicken carcasses. Two sources of astaxanthin were fed to 62-wk-old spent laying hens to improve meat quality: natural astaxanthin (NA) from the red yeast, Phaffia rhodozyma, and synthetic astaxanthin (SA) from chemical synthesis. One hundred forty four ISA Brown laying hens were used in a 6-wk feeding trial. Three treatments consisted of the basal diet (control), SA (100 mg astaxanthin/kg basal diet) and NA (50 mg astaxanthin/kg basal diet). The astaxanthin levels of SA and NA were set to give a similar degree of skin pigmentation. After 6-wk feeding of astaxanthin, the skins from NA and SA were discriminated from the control by electronic nose. However, electronic nose failed to distinguish between SA and NA skins after 6-wk feeding. The astaxanthin level differences between skins of SA and NA were not remarkable during the 6-wk trial. The lipid peroxide formation in skin was significantly decreased by SA but not by NA. The antioxidation effect of SA was detected by electronic nose because SA skin was discriminated from others. NA was a better pigmentation agent than SA, but the reverse was true in antioxidation. Electronic nose is applicable for detecting astaxanthin in chicken, and meat off-flavor caused by lipid peroxidation during storage.

• Transactions of the Korean Society of Pressure Vessels and Piping
• /
• v.16 no.1
• /
• pp.42-48
• /
• 2020

The effect of improving the tensile and J-R fracture toughness properties of SA508 Gr.1a on the LBB margin for the main steam pipe is investigated. The material properties and microstructure images of the existing main steam piping material SA106 Gr.C used in domestic nuclear power plants and the newly selected material SA508 Gr.1a were compared. For each material, LBB margins were calculated and compared through finite element analysis and crack instability evaluation. The LBB margin of the improved SA508 Gr.1a is found to be greatly improved compared to that of the existing SA106 Gr.C and SA508 Gr.1a. This is because of the increased material's strength and J-R fracture toughness compared to the previous materials. In order to analyze the effect of physical property change on the LBB margin, the sensitivity of each LBB margin according to the variation of tensile strength and J-R fracture toughness was analyzed. The effect of the change in tensile strength was found to be greater than that of the change in fracture toughness. Therefore, an increase in strength significantly influenced the improvement of the LBB margin of the improved SA508 Gr.1a.

• Journal of Korean Society of Steel Construction
• /
• v.27 no.2
• /
• pp.131-142
• /
• 2015

In this paper, we present an optimization of truss structures subjected to stress, buckling, and natural frequency constraints. The main objective of the present study is to propose an efficient HA-SA algorithm for solving the truss optimization subject to multiple constraints. The procedure of hybrid HA-SA is a search method which a design values in harmony memory of harmony search are used as an initial value designs in simulated annealing search method. The efficient optimization of HA-SA is illustrated through several optimization examples. The examples of truss structures are used 10-Bar truss, 52-Bar truss (Dome), and 72-Bar truss for natural frequency constraints, and used 18-Bar truss and 47-Bar (Tower) truss for stress and buckling constraints. The optimum results are compared to those of different techniques. The numerical results are demonstrated the advantages of the HA-SA algorithm in truss optimization with multiple constraints.

• Journal of Korean Medical classics
• /
• v.7
• /
• pp.113-160
• /
• 1994

The Sa-Ahm monk, who was believed to have existed in the middle of Cho-Seon Dynasty in Korea, have created an original Sa-Ahm's acupuncture method and written down, "Book of Sa-Ahm's 5 Element Acupuncture Method" using not only laws of creation and suppression in 5 element theory but also its main and other connected meridians according to the daignosis of visceras and bowels. Also the written time and background of its theory have not been known, and after obtaining Ji-San's book on Sa-Ahm's acupuncture method, I studied on them. The results are as follows : 1) The treatment chapter of Book of Sa-Ahm's 5 Element Acupuncture Method was written down by Sa-Ahm himself, and the chapter for Medical Experience was found to be written down by Ji-San. 2) It seemed that Sa-Ahm adopted the main ideas of "Eui Hak Jeong Jon(醫學正傳)" for the section of physiology, pathology and classification of disease symptoms the contents of which covered 40 of 43 parts, and the ideas of "Dong Eui Bo Gam(東醫寶鑑)" for YunGi treatise(運氣篇), and SangHan part(傷寒門) in classification of diease symptoms was intensified by the ideas of "Eui Hak Ip Moon(醫學入門)", and the contents of apoplexy, diseases characterized by acute diarrhea and vomiting, beriberi, diseases of oral cavity were intensified by the ideas of "Chim Ku Kyeong Hearn Bang(鍼灸經驗方)". 3) The written date of the Book of Sa-Ahm's 5 Element Acupuncture Method has been established as 1644 AD(22nd year of In Jo king of Cho-Seon Dynasty) after studying preface, contents and acknowledgement of Heo Im's "Chim Ku Kyeong Hearn Bang(鍼灸經驗方)". 4) The philosophic background of "Sa-Am Acupuncture Method(舍巖鍼法)" seems to be derived from the theories of "I Ching(周易)" and Yin Yang 5 Element Theory(陰陽五行學說), and to be influenced by such medical scholars as Tan Ke(丹溪), Woo Bak(虞搏), and Heo Im(許任).

• The Journal of the Korean Society for Microbiology
• /
• v.13 no.1
• /
• pp.31-36
• /
• 1978

Twenty strains of Salmonella paratyphi A, 55 of S. typhi, 7 of Shigella flexneri, and 14 of Sh. sonnei which were isolated in Taegu area in 1977, were tested for the susceptibility to antimicrobial drugs. All strains of S. paratyphi A were resistant to sulfisomidine(Sa), but none was resistant to chloramphenical(Cm), tetracycline(Tc), streptomycin(Sm), ampicillin, nalidixic acid, kanamycin, gentamicin, amikacin, 1:20 mixture of trimethoprim and sulfamethoxazole, carbenicillin, cephaloridine, and rifampicin. Only one strain. of S. typhi was multiply resistant to Cm, Tc, Sm, and Sa, but all strains were susceptible to the other drugs tested. The resistant strain carried R plasmid; R(Cm Tc Sm Sa). All strains except one were highly resistant to Cm, Tc, Sm, and Sa, and all except one of multiply resistant strains carried R plasmid; R(Cm Tc Sm Sa).

• Korean Journal of Optics and Photonics
• /
• v.16 no.1
• /
• pp.43-49
• /
• 2005

In this paper, we propose a method for optimizing a computer-generated hologram(CGH) by combining the Tabu Search(TS) algorithm with the Simulated Annealing(SA) algorithm. By replacing an initial random pattern of the SA algorithm with an approximately ideal hologram pattern of the TS algorithm, we design a CGH which has high diffraction efficiency(DE). We compared the performance of the proposed algorithm with the SA algorithm using computer simulation and an optical experiment. As a result, we confirmed diffraction efficiency and uniformity to be enhanced in the proposed algorithm.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.34 no.2
• /
• pp.82-107
• /
• 2021

Objectives: The Sa-am Acupuncture Method which is originated from 17^th century is one of Korean traditional acupuncture methods and most widely adopted techniques used by clinicians. This study aims to investigate research trend of Sa-am acupuncture on Korean Obstetrics and Gynecology. Methods: We searched for papers which had Sa-am acupuncture used in women's disease in Korean journals published from 1987 to March 2021. Results: 33 papers were found. 5 clinical studies and 28 case studies were categorized to women's disease groups described in Korean Obstetrics and Gynecology textbook. In most of the studies, Sa-am acupuncture was used with other treatments. In the case reports, each case was diagnosed individually and Sa-am acupuncture was used according to the diagnoses. The most frequently used Sa-am acupuncture method in women's diseases was Sojang jung-geuk. Conclusions: Sa-am acupuncture could be a good treatment for women's diseases. But evidence of relation between Sa-am acupuncture and the disease is insufficient, so more research will be needed.

• Biomedical Science Letters
• /
• v.27 no.1
• /
• pp.35-43
• /
• 2021

Human Sapovirus (HuSaV) is one of the major causes of acute gastroenteritis in humans, and it is used as a molecular diagnostic technique based on polymerase chain reaction (PCR) from humans, food, shellfish, and aquatic environments. In this study, the HuSaV diagnosis technique was used in an aquatic environment where a number of PCR inhibitors are included and pathogens, such as viruses, are estimated to exist at low concentration levels. HuSaV-specific primers are improved to detect 38 strains registered in the National Center for Biotechnology Information (NCBI). The established optimal condition and the composition, including the RT-nested PCR primers and SL® Non-specific reaction inhibitor, were found to have 100 times higher sensitivity based on HuSaV plasmid than the previously reported methods (100 ag based on HuSaV plasmid 1 ng/μL). Through an artificial infection test, the developed method was able to detect at least 1 fg/μL of HuSaV plasmid contaminated with total nucleic acid extracted from groundwater. In addition, RT-nested PCR primer sets for HuSaV detection can react, and a positive control is developed to verify false positives. This study is expected to be used as a HuSaV monitoring method in the future and applied to the safety response to HuSaV from water environments.