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Effect of Formoterol on the Plasma Levels of Theophylline after the Oral Administration to the Children with Respiratory Diseases (소아 호출기 환자에서 경구 투여된 Formoterol이 Theophylline의 혈중농도에 미치는 영향의 연구)

  • Jang, Jin Kyung;Jung, Nak Gyun;Lee, Sook Hyang;Cho, Hea Kyoung
    • Korean Journal of Clinical Pharmacy
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    • v.10 no.3
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    • pp.107-110
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    • 2000
  • Theophylline and $\beta$-adrenergic agonists are frequently used together in patients with respiratory diseases. However the clinical impact of $\beta_2$-adrenergic agonists on the blood concentration of theophylline is not fully evaluated. Formoterol, a newly available oral ${\beta}_2$-adrenergic agonist is frequently used in pediatric respiratory patients. The objective of this study was to investigate the effect of oral formoterol on theophylline's blood concentration. Randomized prospective study was conducted. Twenty-four children were enrolled on the study. Their age ranged 2 to 73 months (mean 35.8 months). Theophylline group (12 patients) received 10 mg/kg/day of for theophylline orally. Theophylline/formoterol group (12 patients) received 10 mg/kg/day of theophylline and $4\;{\mu}g/kg/day$ of formoterol orally. All medications were administered at least for 5 days starting on admission day. Theophylline's trough concentrations were obtained on days 3 and day 5. Pulse rates were recorded before the study medications were given on admission, and days 3 and day 5. Statistical significance was calculated by two-tailed Student's t-test. Theophylline's levels in children given theophylline and formoterol together were lower an those given theophylline alone ($6.38\pm0.90\;{\mu}g/ml\;vs\;7.43\pm0.77\;{\mu}g/ml$ on day 3(p<0.05), $5.62\pm0.56\;{\mu}g/ml\;vs.\;6.78\pm0.61\;{\mu}g/ml$ on day 5 (p<0.05)). In both groups, theophylline's trough concentration on day 5 were lower than day 3. There was no significant side effects in both groups. In conclusion, the new ${\beta}_2$ selective adrenergic agonist formoterol reduced serum theophylline levels in children with respiratory diseases. Further investigation is needed to clarify the long term effect of this drug interaction.

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Effects of Repeated Food Deprivation on Growth and Survival of the Juvenile Olive Flounder Paralichthys olivaceus (넙치 Paralichthys olivaceus 치어의 성장과 생존에 미치는 반복적 절식의 영향)

  • Kim, Hyo-Chan;Kang, Duk-Young;Chang, Young-Jin
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.41 no.2
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    • pp.125-133
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    • 2008
  • To investigate the effect of repeated food deprivation and refeeding on the hyperphagia, compensatory growth, feed efficiency, body composition, hepatosomatic index (HSI), and survival rate of the juvenile olive flounder Paralichthys olivaceus, an experiment was conducted for 90 days. Feeding treatments consisted of the following five regimes for 90 days from August to October, 2005: C: daily satiation feeding (control), S1: 1-day satiation feeding after 1-day food deprivation, S2: 1-day satiation feeding after 2-day food deprivation, S3: 1-day satiation feeding after 3-day food deprivation and S4: 1-day satiation feeding after 4-day food deprivation, respectively. Although the monthly feed intake (MFI) of the control was significantly higher than that of all of the starved groups, the daily feed intake (DFI) was more higher in S1, S2, and S3 than that in the control as a result of hyperphagia after starvation. While the feed efficiency in the summer (to day 30) decreased in all of the starved groups with prolongation of the starvation period, the feed efficiency in the autumn (to day 90) was increased with prolongation of the starvation period. The whole body proximate composition and HSI were also affected by starvation. The crude protein, lipid, and HSI decreased with prolongation of the starvation period, whereas the crude ash and moisture increased. The growth rate and condition factor also decreased in proportion to the starvation period. The survival rate was highest in the control and was the lowest in S4. In this study, although hyperphagia occurred in the deprived groups, we knew that the compensatory growth did not always occur.

Relationships between Young Children's Day Care Experience and Their Attachment Relationships with Parents and Socioemotional Behavior Problems (영유아기의 탁아 경험과 유아의 부모에 대한 애착 및 사회정서적 문제행동과의 관계)

  • Kim, Sook Ryong
    • Korean Journal of Child Studies
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    • v.18 no.2
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    • pp.5-18
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    • 1997
  • The purpose of the current study was to determine whether preschoolers' attachment relationships with their parents and socioemotional behaviors are related to their day care experiences in infancy and at the present time. The participants consisted of 59 preschoolers and their mothers from 2-parent, white, middle-class dual earner families in Madison, Wisconsin. Preschoolers' attachment quality was measured by two representational instruments: the Separation Anxiety Test and "My Family and Friends". Mothers completed questionnaires about their family background and their children's day care history. The quality of current day care was obtained from directors' reports about regulatable features of the day care centers. Teachers completed the Preschool Behavior Questionnaire. Data was analyzed by hierarchical multiple regression analysis. The results showed that the quality of preschoolers' attachment relationships with parents were significantly related to the amount of day care during infancy, the quality of current care, and children's gender. In addition, the amount of infant day care appeared to have negative relations with children's socioemotional behavior problems as evaluated by teachers.

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- The Change of Product Cost to 5 working day's a week and Solutions of Productivity in a Type of Industries for Safety Management - (경영관리시스템의 안전적인 운영을 위한 준 5일 근무제에 따른 원가변화 분석과 업종별 생산성 향상 대책)

  • Kim Tae Ho;Kim Hyung Jun
    • Journal of the Korea Safety Management & Science
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    • v.6 no.3
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    • pp.311-326
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    • 2004
  • The 5 working day's a week increase to fixed cost. Specially, the small & medium size company more increase to manufacturing cost. The introduction of 5 working day's rule influence to labor cost in manufacturing cost. Also, it make disappearance to fixed cost of 0.5 working day. Almost manufacturing company expect to have difficulty in product cost. The case of japan, many manufacturing company move to Asian countries after introduction of 5 working day's a week rule. The purpose of this study are the analysis of change product cost and suggest to solutions of productivity for a type of industries..

The Change of Product Cost to 5 working day's a week and Solutions for a type of industries (주 5일 근무제에 따른 제품원가변화 분석과 업종별 대책)

  • 김태호
    • Proceedings of the Safety Management and Science Conference
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    • 2002.11a
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    • pp.179-193
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    • 2002
  • The 5 working day's a week increase to fixed cost. Specially, the small & medium size company more increase to manufacturing cost. The introduction of 5 working day's rule influence to labor cost in manufacturing cost. Also, it make disappear to fixed cost of 0.5 working day. Almost manufacturing company expect to have difficulty in product cost. The case of japan, many manufacturing company move to Asian countries after introduction of 5 working day's a week rule. The purpose of this study are the analysis of change product cost and suggest to solutions for a type of industries.

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Mother's perception for the importance of selected criteria of day care center according to the demographic characteristics (사회인구학적 변인에 따른 어머니의 보육시설 선택기준에 대한 중요도)

  • 안지연
    • Journal of the Korean housing association
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    • v.6 no.2
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    • pp.139-153
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    • 1995
  • The primary goals of this study were to find out how is the mother's perception for the importance of criteria when choosing day care center, and to examine how different there are according to the demographic characteristics, futhemore to investigate how different the importance of criteria when mothers choose an ideal day care center are given the present situation, when mother choose day care center are according to the related variables. The major results of this research are shown as follow: 1. Generally, there was significant differences in the mother's perception for the importance of quality criteria of day care center according to the demongraphic characteristics. 2. There were statistically significant differences in the importance of criteria when mothers choose day care center in 2 conditions: 1) given the present situation(income, trasportation, location of workplace etc.). when mothers choose day care center 2) when mothers choose an ideal day care center regardless of the present situation) according to several demographic variables.

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Child Care Arrangement and the Needs of Day Care Service Program among the Employed Mothers of the Urban Low Income Class (도시 저소득층 취업모의 자녀위탁실태 및 탁아서비스에 관한 요구 조사)

  • 오선영
    • Journal of the Korean Home Economics Association
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    • v.31 no.2
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    • pp.141-157
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    • 1993
  • The purpose of this study were to collect the data for searching the better day care service programs among the employed mothers of the urban low income class. The Subject were 280 low income class employed mothers with the child under age of six, who lived at the Gwang-ju City. The frequency, percentage, and χ2test were calculated for the analysis of the collected data. The Results were as follows ; 1) Most of the urban low income class employed mothers needed day care facilities. 2) Urban low income class employed mothers preferred a center-based day care program to any other type of day care program. They also preferred the whole-day day care service 8 A.M. to 6 pp.M. rather than the half-day care service. Mothers with the child at the age of 3 to 6 years mostly wanted day care program service. 3) They expected the government or their companies to support considerable amount of day care service fee. Most of mothers emphasized the child's every day life's and love for the children was most preferred. Mothers also wanted 14-16 years for teacher's education career.

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A study on the Intake-Balance of Iron Copper and Cobalt of College men in Korea (한국 남자대학생의 Iron, Copper 및 Cobalt 섭취량과 평형에 관한연구)

  • 최인선;장수영;오승호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.19 no.5
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    • pp.418-428
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    • 1990
  • This study measured each daily intake and excretion of iron copper and cobalt of eight 20-26 years old college men during four weeks by means of analyzing their food intake urine and feces keeping their normal living pattern and maintenance body weight. This study also compared the actual measurement value of iron intake by atomic absorption spectrophoto-meter with the conversion value of it by food table. The results were as follows. Each person's average intake daily was iron 9.19±0.32mg/day, copper 0.56±0.06mg/day and cobalt 1.86±0.18mg/day. Each person's average urinary excretion daily was iron 0.53±0.07mg/day, copper 0.07±0.03mg/day and cobalt 0.13±0.01mg/day. Each person's average fecal excretion daily was iron 1.73±0.14mg/day copper 0.16±0.01mg/day and cobalt 0.46±0.08mg/day. The actual measurement value was 9.19±0.32mg/day and its conversion value 14.07±0.29mg/day : the former was 35% lower than the latter.

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The Social Competence of Children with Reference to Day Care Center`s Structural, Process Variables and Demographic Variables (보육시설의 구조적, 과정적 변인 및 인구통계학적 특성에 따른 유아의 사회적 능력)

  • 전춘애;이미숙
    • Journal of Families and Better Life
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    • v.20 no.1
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    • pp.115-124
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    • 2002
  • The purpose of this study is to examine the social competence of children with reference to day care center's structural, process variables and demographic variables. The subjects were 156 children who attend day care center, aged from 3 to 5 years and 9 teachers in Seoul or the province of KyungkiDo. Data were gathered via the structured Questionnaires distributed to the teachers to rate children's social competence and their own job satisfaction. And two observers rated teacher-child interaction in day care center The major findings are as follows The variables predicting children's social competence were child's sex, age, period of attendance in day care center, teacher's job satisfaction, and group size. Especially this study suggests that teachers who are highly satisfied with their job and small group size influence children's social competence positively.

A Study of Housewives' Attitudes on the Festive Days and Dishes in Korea -In the Region of Seoul and Choongchung Province- (우리나라의 명절과 음식에 관한 주부들의 인지도 연구 -서울과 충청지역을 중심으로 -)

  • 조후종;조진아;최성은
    • Journal of the East Asian Society of Dietary Life
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    • v.8 no.3
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    • pp.235-245
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    • 1998
  • The purpose of this research was to determine the dishes most commonly served during various festive days. This research studied the habits of housewives in Seoul and In the Choongchung province who have children in high school. 1. Most of the housewives in Seoul graduated from high school. On the other hand. those in the Choongchung province graduated from elementary school in their education backgrounds. The monthly income ranged from 1,550,000 won to 1,190,000won to 1,190,000 won for the housewives of Seoul, and from 1,000,000 won to 1,490,000 for those of Choongchung. The nuclear family system was dominated in both areas and 63.8% of the housewives had a full-time job. 2. "Sulnal(The New Year's Day), Chusuk(Thanksgiving Day), Jungwol-daeborum(The 1st Full-Moon Day)" are among the festive days celebrated in 85% of the both areas, and "Yuwol-Yudu(6th, June), Chungyangjul(9th, September), Naphyang(8th, September)" were celebrated in 0.5%. 3. Traditional festive dishes with respect to the festive days were as follows. Tuckuk(rice cake soup) was a favorite food in Sulnal(The New Year's Day), Burum(Peanut,pine-nut, walnut, etc) in Jungwol-daeborum(The 1st Full-Moon Day), Samgyetang(chicken soup) in Dongji Songpyen(rice cake) in Chusuk(Thanksgiving day) and Patjuk(small red beans soup) in Dongji (22th, December). No significance was found in the number of dishes. 4. The Regional differences the festive days such as Sulnal(The New Year's Day), Ipchun(4th, February), Jungwol-daeborum(The 1st Full-Moon Day), Samwol-samjit(3th, March) Sawolchopail(Budda's birthday), Tano(5th, May), Yuwol-yudu(6th, March) Sawolchopail Budda's birthday), Tano(5th, May), Yuwol-yudu(6th, June), Chilwol-chilsok(7th, July), Suddal -gumum (The year's last day) were very significant 5. The festive days should continue. On the other hand, the menu(dishes) of the festive days should be simplified.hould be simplified.

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