• Title/Summary/Keyword: S-GOT

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The Glycosides of Araliaceaus Drugs and their Biological Activities

  • Hahn, Dug-Ryong;Kasai, Ryoji;Kim, Jeung-Hee;Taniyasu, Shigenori;Tanaka, Osamu;Kim, Chang-Johng;Park, Myong-Ja
    • Korean Journal of Pharmacognosy
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    • v.17 no.1
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    • pp.78-84
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    • 1986
  • Among the Araliaceae plants indigenous to Korea, those whose medicinal usage are comparatively high have been selected in this serial studies. Chiisanoside and acanthoside D were isolated and identified from the Acanthopanax chinensis leaves and root bark. Chiisanoside and acanthoside D have been found to have the lowering S-GPT, S-GOT value and BSP-retention rate and survival rate, anti-histaminic effect in the toxic state through the bio-pharmacological experiments. ${\alpha}-hederin$, hederagenin pentaglycoside were isolated both stem bark of Kalopanax pictum Nakai var. magnificum and Kalopanax pictum Nakai var. Max. respectively. Syringoside, acanthoside D were also isolated from the root bark of Acanthopanax koreanum. The biological activity of ginsenoside $Rb_1$, $Rg_1$, Re were examined. Ginsenoside $Rb_1$, $Rg_1$, Re promotes the antileaking effect in X-ray (Co 60) irradiated toxic state.

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Effect of Cheunggansoyosan-gamibang on Hyperlipidemic mice (청간소요산가미방(淸肝逍遙散加味方)이 생쥐의 고지혈증에 미치는 영향)

  • Baek, Yong-Ju;Yang, Seung-Jung;Park, Hye-Sun;Kim, Kyoung-Su;Hong, Seok;Jeon, Sang-Yoon
    • Herbal Formula Science
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    • v.14 no.1
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    • pp.120-132
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    • 2006
  • Hyperlipidemia is one of dangerous factors causing the arteriosclerosis. For the study of Cheunggansoyosan-gamibang( CGSYS) on antihyperlipidemic effect, we had fed mice divided to three groups (basal diet, hyperlipidemic diet, hyperlipidemic diet + CGSYS), and observed the change of weight, total cholesterol. triglyceride, HDL-cholesterol. LDL-cholesterol. sGOT, sGPT on the serum per every 7days for 6weeks. Also to compensate for the results above, we had tested rat liver. The results of this Study were obtained as fallows ; 1. Cholesterol change on blood was decreased by CGSYS. 2. Total cholesterol. triglyceride and LDL-cholesterol were significantly decreased by CGSYS. 3. HDL-cholesterol was significantly increasd by CGSYS. 4. sGPT was significantly decreased by CGSYS. 5. sGOT was not changed by CGSYS. 6. In case of supplying CGSYS. fatty degeneration was not observed in liver portal area. This study suggests that Cheunggansoyosan-gamibang was significant effect with hyperlipidemia.

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Development of the Structure and Changes of the Jeogori (Part II) -Focused on Goryeo Era- (저고리 세부구조의 발생과 그 형태변화에 대한 연구 (제2보) -고려시대를 중심으로-)

  • Chae, Keum-Seok
    • Journal of the Korean Society of Clothing and Textiles
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    • v.31 no.3 s.162
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    • pp.351-363
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    • 2007
  • Most of the proceeded research of jogories in the Goryeo era are about the total clothing system of the men and women's dress and not many have studied of the developing process of the jeogories specific structures. Therefore, the purpose of this study is to figure out the origin and the alteration of a git, gil, seop and gorem which forms a jeogori after the Unified Shilla era. The range of this study os from 918 to 1392, Goryeo era and 80 pieces 7 portraits and 5 Buddhist relics were for references. This study reached the following conclusions. First, oat git, gil, seop, somae and gorem forms the Goryeo era's jogori. Second, as the length of the joegori got shorter then the past, the ryeongem also got shorter and changed to an oatgit. Third, as most of the opening side of the jeogori started to fix on the right. Forth, an extra cloth attached on the gil developes a seep that be originates in Unified Shilla when get shoter. Fifth, there were wide and very long sleeves that came all the way down to the hand, narrow sleeves and long sleeves. Sixth, Goryeo era's jeogori had ribbons and cloth buttons to fix the form instead of a belt.

A STUDY ON MENTAL HEALTH STATE OF HIGH SCHOOL STUDENTS (고등학생의 정신건강 상태에 관한 연구 -SCL-90을 이용, 서울시 인문계 1 . 3학년을 중심으로-)

  • 김은주
    • Korean Journal of Health Education and Promotion
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    • v.5 no.2
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    • pp.110-141
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    • 1988
  • This study was conducted to find out the mental health state of high school students. First-year students and third-year students af liberal high schools is Seoul were subject to this study. Questionnaire of Symptom Checklist-90 and various factors was adopted for the survey. A total of 916 questionnaires was sellected for the analysis, and the results are obtained as follows; 1) The characteristics in responses to mental health scale showed that obsessive-compulsive scale score was the highest, followed by interpersonal-sensitivity, depression, hostility, and anxiety. The subject group of the students showed higher scores in nine symptom dimensions except somatization than other normal group. 2) Girl-students showed higher scores than boy-students in somatization, depression, and anxiety, whereas the opposite was true in hostility. 3) Third-year students got high scores, in somatization, anxiety and Depression. 4) Parental marriage state of the repondents showed significant differences in nine symptom dimensions of mental health. Scores of the students with parents was the lowest, followed by those of students with only mother, only father and the rest(no parents, divorced, sepaerated, step-parent) in increasing order. 5) Smoking students showed high score in obsessive-compulsive, depression, hostility, paranoid ideation, and psychoticism. Especially in hostility, they got much higher score. 6) Students with poor record at school got higher scores in every symptom dimension than those with good record at school, especially in obsessive-compulsive and depression scale. 7) Parents' attitude toward student showed significant effect on every scale. Students under over-expectation or indifference from parents were in bad mental health state. 8) Students who have advisor proved to be in better mental health state than those who never consult their personal problems with others. 9) He who has family history got higher scores in some scales. 10) Respondents who looked upon what they have learned in high school as being rather an obstacle to sound social life got high scores in all the symptom dimensions and next came those of the students who answered that there were a lot of unnecessary things in their learning. 11) Those for whom it would not quite necessary to enter college if there were little formal schooling discrimination in society got high scores in obsessive-compulsive, interpersonal sensitivity, depression, hostility, and in psychoticism, especially higher in obsessive-compulsive scale. 12) Mental health state of the students who are influenced by the social surroundings, mass media, and the home environments showed high score in 8 symptom dimensions. 13) Abnormal response frequency of this sample is as follows; 24.0% of boys, 23.8% of girls, 22.5% of the first-year students, and 26.9% of the third-year students. There were significant difference among the grades. 14) The factors of distinctive correlation between the dimensions of SCL-90 and 16 factors were the father's negative attitude and depression, negative responses on teaching contents and anxiety, and smoking and hostility. In conclusion, mental health state of liberal highschool students on the whole showed worse than other normal groups. It had close terms with relation with their parents, schoolwork, smoking, teaching contents, the social surrounding, mass media, and the home environments. Thus I believe there need not only mental health education of students, training of teachers, counceling of parents, but also changes in teaching contents, and the improvement of educational system and the social surroundings under the national support.

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Factors Affecting the Postoperative Outcome in Adult Cardiac Surgery with Cardiopulmonary Bypass (심폐바이패스를 이용한 성인 심장수술 시 환자회복에 영향을 미치는 인자)

  • Lee, Sung-Chul;Kim, Yun-Tae;Moon, Seong-Min;Hyun, Kyung-Yae;Kim, Dae-Sik;Choi, Seok-Cheol
    • Journal of Life Science
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    • v.18 no.11
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    • pp.1493-1498
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    • 2008
  • We defined factors affecting the postoperative outcome in adult cardiac surgery with cardiopulmonary bypass (CPB). Thirty-two adult patients scheduled for elective cardiac surgery participated in this study. Levels of leukocyte, glutamic oxaloacetic transaminase (GOT), troponin-I (cTNI), interleukin-6 (IL-6), D-dimer and neuron-specific enolase (NSE) were significantly elevated, whereas platelet count declined in cardiac surgery with CPB. GOT and D-dimer levels at CPB-off each had a positive significant correlation significantly with 24 hrs-bleeding, total bleeding, mechanical ventilatory assist time, ICU stay time and length of hospitalization. BUN levels at CPB-off were directly related to total bleeding, mechanical ventilatory assist time, ICU stay time and length of hospitalization. Platelet count at CPB-off was inversely related to mechanical ventilatory assist time, ICU stay time and length of hospitalization. Creatinine concentration at CPB-off interrelated positively with mechanical ventilatory assist time and ICU stay time. NSE levels at CPB-off had a positive relationship with postoperative 24 hrs-bleeding. The length of hospitalization was prolonged proportionally to the elevation of cTNI levels in cardiac surgery. Aortic cross-clamping and total CPB times also related with increase of 24 hrs and total bleeding volumes and the length of hospitalization. IL-6 and ET-1 had no mutual relation with any postoperative outcome. These data suggest that GOT, BUN, creatinine, D-dimer and platelet levels are the most important factors affecting postoperative outcomes and patient's recovery in adult cardiac surgery with CPB.

Inheritance of four Isozymes(GOT, ACP, MDH, and ADH) in Populus alba × P. glandulosa F1 Hybrids (Populus alba × P. glandulosa의 4가지 Isozyme (GOT, ACP, MDH, ADH)의 유전(遺傳))

  • Son, Doo Sik;Joo, Sung Hyun
    • Journal of Korean Society of Forest Science
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    • v.71 no.1
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    • pp.90-98
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    • 1985
  • Inheritance of four isozymes, GOT, ACP, MDH and ADH, in Populus alba ${\times}$ P. glandulosa was investigated with starch gel electrophoresis. All four isozymes showed bands. For GOT, six or seven loci were postulated and observed segregation of hybrids at five variable loci was in agreement with expected segregation. Two loci were postulated in ACP; one locus showed no variation but the other locus showed variation. As one additional band was found in P. alba ${\times}$ P. alba (italy), hybrids from P. alba ${\times}$ P. alba ${\times}$ P. glandulosa showed more variation than hybrids from P. alba ${\times}$ P. glandulosa. One monomorphic locus and two variable loci were postulated in MDH. For ADH, both parents were turned out as homozygotes but for different alleles and thus all progenies were heterozygotes. ADH in hybrids seems to be a dieter enzyme as it showed on additional band between two parental bands. There were no variation in band betweens of four enzymes among the clones of P alba and P. glandulosa, respectively.

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Effect of Mahwang (Ephedrae herba) extract on serum Biological Values and Blood cell Composition (마황추출액이 혈액의 생물학적 수치 및 혈구 구성에 미치는 영향)

  • Park Young-Hoon
    • Korean Journal of Plant Resources
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    • v.19 no.2
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    • pp.296-299
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    • 2006
  • Effects of mahwang(Ephedrae herba) extract on plasma lipid composition, GOT, GPT activity and blood cell composition were investigated in rats. Concentrations of FFA was not significantly different in all treatment groups. Concentrations of triglyceride and total cholesterol in plasma were decreased in mahwang(Ephedrae herba) extract groups. However concentrations of HDL-cholesterol and LDL-cholesterol showed no significant difference in all treatment groups. GOT activities were increased in mahwang(Ephedrae herba) extract 300mg/kg group. However the values of GPT showed no significant difference in all treatment groups. Counts of RBC were increased in mahwang(Ephedrae herba) extract 300mg/kg group. Counts of WBC showed no significant difference in all treatment groups. In WBC composition, neutrophils were increased, but other cells were not affected by mahwang extract treatment.

Relationship Between Management Practices of Hamburger Chain Restaurants and Job Satisfaction of Restaurant Employees (햄버거 체인점의 관리실태와 종업원 직무만족과의 관계)

  • Chun, A.-Dah;Lyu, Eun-Soon;Kwak, Tong-Kyung
    • Journal of the Korean Society of Food Culture
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    • v.10 no.1
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    • pp.57-66
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    • 1995
  • The purpose of this study was to evaluate the management practices and to measure the degree of job satisfaction of employees of hamburger chain restaurants in Seoul. Management practices were evaluated in terms of service, quality, cleanliness and shift management in 30 hamburger restaurants of 3 domestic and 3 foreign chain brands. Employee job satisfaction was measured by using questionnaires of Job Descriptive Index. 200 employees from the same 30 restaurants were participated in the survey. Results were analyzed by using SAS program in terms of t-test, one-way ANOVA, and Pearson's correlation. The results are as follows: 1. The factor of quality got the highest score and cleanliness the second, service the third, and shift management got the lowest score in the evaluation of management practiecs of hamburger chain restaurant. The foreign brands showed significantly higher scores than the domestic ones in every measured factors. 2. The factor of coworkers got the highest score and then supervision, the work-itself, promotion and pay got the next highest scores in descending order in measured Job satisfaction. The foreign brands showed significantly higher scores than domestic ones in JDI. 3. The foodservice employees rated work-itself was considered by employees the most important job satisfaction factor, and the next important factor was pay and then coworkers, supervision, and promotion. 4. The significant positive relationship between management practice factor of shift management and all the factors of job satisfaction except the factor of pay were found.

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Related factors of clinical practice satisfaction and social support in dental hygiene students (일부 치위생과 학생들의 실습 만족도와 사회적 지지 관련 요인)

  • Lim, Sun-A;Youn, Hye-Jeong
    • Journal of Korean society of Dental Hygiene
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    • v.14 no.6
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    • pp.935-942
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    • 2014
  • Objectives: The purpose of the study was to investigate the related factors of clinical practice satisfaction and social support in dental hygiene students. Methods: A self-reported questionnaire was filled out by 420 dental hygiene students in Gwangju and Jeonnam from March 8 to April 8, 2014. Except 26 incomplete answers, 394 data were analyzed. The instrument consisted of general characteristics of the subjects(7 questions), social support(7 questions), and satisfaction level with clinical practice(22 questions). The instrument for satisfaction level with clinical practice included self-esteem(1 question), interest and usefulness(2 questions), knowledge application(1 question), place of clinical practice(1 question), and influence by practice leader(1 question). Cronbach alpha was 0.773 in the study. The instrument of social support was adapted from Park and reconstructed. Social support included emotional support(11 questions), self-esteem support(7 questions), and informative support(4 questions). Social support was score by Likert 5 scale and higher score showed the higher social support. Results: The dental hygiene students got a mean of $3.11{\pm}0.55$ in clinical practice satisfaction. They got 3.35 points in satisfaction with major and 3.32 in satisfaction with curricula(p<0.001). They got a mean of $3.68{\pm}0.55$ in social support. They got $3.69{\pm}0.57$ in emotional support; $3.81{\pm}0.59$ in self-esteem support; and $3.53{\pm}0.66$ in informative support. The influencing variables on satisfaction with clinical practice were self-esteem support(B=0.202), satisfaction with major(B=0.234), and satisfaction with curricula (B=0.128). Conclusions: There was a close relationship between satisfaction with clinical practice and social support. In order to enhance the satisfaction with clinical practice, it is necessary to connect self-esteem support with major satisfaction and curricula satisfaction.

Effects of rutin and hesperidin on total cholesterol concentration, transaminase and alkaline phosphatase activity in $CCl_4$ treated rats (루틴과 헤스페리딘이 간 독성을 일으킨 흰쥐의 cholesterol 함량, transaminase, alkaline phosphatase 효소활성에 미치는 영향)

  • Son, Heung-Soo;Kim, Hyun-Sook;Ju, Jin-Soon
    • Applied Biological Chemistry
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    • v.34 no.4
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    • pp.318-326
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    • 1991
  • This study was devised to investigate the effects of flavonoids on carbon tetrachloride toxicity of rats. Through the experiments, the contents of total cholesterol, transaminase(GOT, GPT) and alkaline phosphatase(Alk. P) activities in the liver and serum were determined. The results obtained are summarized as follows; (1) The liver cholesterol concentration of flavonoid injected groups were remarkably increased up to 45% at 2 days after $CCl_4$ injection and then the values were almost recovered to the level of control group at 4 days after $CCl_4$ injection. The increase of serum cholesterol content was inhibited by the flavonoids after $CCl_4$ injection, but the result was not significant. (2) Flavonoids injection was found to have the ability to decrease the elevated serum GOT, Alk. P activities resulting from injection of $CCl_4$ and induce rapid recovery from such an elevated level and the extent of such a decreasing action was greatest in hesperidin injection group. The liver microsomal Alk. P and GOT activities were not affected by the treatment of flavonoids. (3) The elevated serum and liver microsomal GPT activities induced by $CCl_4$ injection were inhibited by the injection of flavonoids.

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