• Radiation Oncology Journal
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• v.16 no.1
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• pp.51-61
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• 1998

Purpose : Treatment of choice for uterine cervix cancer stage IIB is radiotherapy. We analyzed survivals, Prognostic factors, patterns of failure and complications. Materials and Methods : This is a retrospective analysis of 167 patients with stage IIB carcinoma of uterine cervix treated with curative external pelvic and high dose rate intracavitary radiotherapy at the Department of Therapeutic Radiology, Soonchunhyang University Hospital from August 1985 to August 1994. All the patients followed up from 3 to 141 months(mean 60 months) and age of patients ranged from 31 to 78 years at presentation(mean : 55 years). Results : Overall complete response rate was $84\%$. The response rate for squamous cell carcimoma and adenocarcinoma were $86\%$ and $60\%$, respectively. Overall 5-years survival rate and disease free survival rate was 62 and $59\%$, respectively Mass size and treatment response were significant Prognostic factors for survival Pathologic type and parametrial involvement were marginally significants Prognostic factors. Local failure was 43 cases, distant metastasis was 14 cases and local failure plus distant metastasis was 3 cases, and most of local failures occurred within 24 months, distant metastasis within 12 months after treatment Twenty eight($16.8\%$) patients developed late rectal and urinary complications There were tendency to increasing severity and frequency according to increased fractional dose and total(rectal and bladder) dose. Conclusions : Survival rate was significantly related to tumor size and radiotherapy response. Tumor size should be considered in the clinical s1aging. To increased survival and local control, clinical trials such as decreasing duration of radiotherapy or addition of chemotherapy is needed. To detect early recurrence, regular follow up after RT is important. Because total rectal and bladder dose affected late complications. meticulous vaginal packing is needed to optimize dose of normal tissues and to decrease late complications.

• Journal of Sericultural and Entomological Science
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• v.36 no.2
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• pp.138-146
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• 1994

The structural characteristics of Antheraea yamamai and Antheraea pernyi silk were investigated by using x-ray diffraction method, IR spectroscopy and polarizing microscopy. The amino acid composition, fiber density, thermal decomposition temperature and glass transition temperature were also measured for relating these physical properties to the structure in comparison with those of Bombyx mori silk fiber. There was no significant structural difference between A. yamamai and A. pernyi silk fiber on an examination of x-ray diffraction curve and IR spectrum. Both of these wild silk fibers showed double diffraction peaks at the Bragg angle 2Θ16.7˚ and 20.5˚by x-ray diffraction analysis as well as IR absorption peaks for the bending vibration of specific groups related to ala-ala amino acid sequence. On the other hand, the x-ray diffraction curve and IR spectrum of Bombyx mori silk fiber are different from those of wild silk fibers, indicating different crystal structure as well as amino acid sequences. It showed under the polarizing microscope examination that the birefringence and optical orientation factor of wild silk fibers are much lower than those of B. mori silk. Also, the surface of degummed wild silk fibers was characterized by the longitudinal stripes of microfibrils in the direction of fiber axies. The amino acid composition, which is strongly related to the fine structure and properties, was not significantly different between these two wild silk fibers. However, the alanine content was somewhat less and polar amino acid content more for A. yamamai. As a result of fiber density measurement, the specific gravities of B. mori, A. pernyi and A. yamamai were 1.355~1.356, 1.308~1.311, 1.265~1.301g/㎤ in the order, respectively. The calculated crystallinity(%) was 64% for B. mori and 51~52% for wild silk fibers, which showed same trend by IR method in spite of somewhat higher value. The thermal decomposition behaviour was examined by DSC and TGA, showing that the degradation temperature was in the order of B mori, A. prernyi and A. yamamai at around 350$^{\circ}C$. It was also observed by TGA that the decomposition seems to proceed step by step according to their specific regions in the fiber structure, resulting the difference in their thermal stabilities. The glass transition temperature was turned out to be 220$^{\circ}C$ for B. mori, 240$^{\circ}C$ A. yamamai and 255$^{\circ}C$ A. pernyi by the dynamic mechanical analysis. It is expected that the chemical properties are affected by the dynamic mechanical behavior in accordance with their structural characters.

• Journal of the Korean Society of Radiology
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• v.82 no.3
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• pp.654-669
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• 2021

Purpose To evaluate the accuracy of MRI in predicting the pathological complete response (pCR) and the residual tumor size of breast cancer after neoadjucant chemotherapy (NAC), and to determine the factors affecting the accuarcy. Materials and Methods Eighty-eight breast cancer patients who underwent surgery after NAC at our center between 2010 and 2017 were included in this study. pCR was defined as the absence of invasive cancer on pathological evaluation. The maximum diameter of the residual tumor on post-NAC MRI was compared with the tumor size of the surgical specimen measured pathologically. Statistical analysis was performed to elucidate the factors affecting pCR and the residual tumor size-discrepancy between the MRI and the pathological measurements. Results The pCR rate was 10%. The diagnostic accuracy of MRI and the area under the curve for predicting pCR were 90.91% and 0.8017, respectively. The residual tumor sizes obtained using MRI and pathological measurements showed a strong correlation (r = 0.9, p < 0.001), especially in patients with a single mass lesion (p = 0.047). The size discrepancy between MRI and the pathological measurements was significantly greater in patients with the luminal type (p = 0.023) and multifocal tumors/non-mass enhancement on pre-NAC MRI (p = 0.047). Conclusion MRI is an accurate tool for evaluating pCR and residual tumor size in breast cancer patients who receive NAC. Tumor subtype and initial MRI features affect the accuracy of MRI.

• Tuberculosis and Respiratory Diseases
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• v.52 no.1
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• pp.24-36
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• 2002

Background: Bronchial reactivity is known to be a component of airway hyperresponsiveness, a cardinal feature of asthma, with bronchial sensitivity, and is increments in response to induced doses of bronchoconstrictors as manifested by the steepest slope of the dose-response curve. However, there is some controversy regarding methods of measuring bronchial reactivity and clinical impact of such measurements. The purpose of this study was to evaluate the clinical significance and assess the clinical use by analyzing the relationship of the bronchial sensitivity, the clinical severity and the changes in pulmonary function with bronchial reactivity. Method: A total of 116 subjects underwent a methacholine bronchial provocation test. They were divided into 3 groups : mild intermittent, mild persistent, moderate and cough asthma. Severe patients were excluded. Methacholine PC20 was determined from the log dose-response curve and PC40 was determined by one more dose inhalation after PC20. The steepest slope of log dose-response curve, connecting PC20 with PC40, was used to calculate the bronchial reactivity. Body plethysmography and a single breath for the DLCO were done in 43 subjects before and after methacholine test. Results: The average bronchial reactivity was 38.0 in the mild intermittent group, 49.8 in the mild persistent group, 61.0 in the moderate group, and 41.1 in the cough asthma group. There was a weak negative correlation between PC20 and bronchial reactivity. A heightened bronchial reactivity tends to produce an increased clinical severity in patients with a similar bronchial sensitivity and basal spirometric pulmonary function. There were significant correlations between the bronchial reactivity and the initial pulmonary function before the methacholine test in the order of sGaw, Raw, $FEV_1$/FVC, MMFR. There were no correlations between the bronchial sensitivity and the % change in the pulmonary function parameters after the methacholine test. However, there were significant correlations between the bronchial reactivity and the PEF, $FEV_1$, DLCO. Conclusion: There was weak significant negative correlation between the bronchial reactivity and the bronchial sensitivity, and the bronchial reactivity closely reflected the severity of the asthma. Accordingly, measuring both the bronchial sensitivity and the bronchial reactivity can be of assistance in assessing of the ongoing disease severity and in monitoring the effect of therapy.

• Economic and Environmental Geology
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• v.45 no.3
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• pp.307-315
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• 2012

In this paper, a laboratory model test was conducted to evaluate grouting efficiency of ordinary portland cement(OPC) and micro cement used in MIS(Micro-Injection Process System). For this research, a injection equipment was developed for pressure permeation which can evenly simulate various grouting tests in a laboratory and suggested a standard for the production of the test specimen. Using the injection device, the laboratory injection tests of grouts were prepared with water/cement ratio of 1:1, 2:1, 3:1, 4:1, and 5:1. The analysis of injection test for pressure permeation showed that the efficiency of injection increases linearly as the water/cement ratio increases. Comparison of efficiency of the injection indicates that MIS with a relatively smaller average diameter shows more efficient injection than the OPC. In the low ratio of water/cement as 2:1~1:1, the injection efficiency of OPC was especially poor. Also, a nonlinear grout volume-injection time is represented by a hyperbolic model and grout volume predicted by hyperbolic model was compared with the value measured. From the comparison, it shows that the hyperbolic model has the potential of evaluating the efficiency of grouting.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.11
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• pp.5542-5550
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• 2012

Third-order shear deformation theory is reformulated using the nonlocal elasticity of Eringen. The equation of equilibrium of the nonlocal elasticity are derived. This theory has ability to capture the both small scale effects and quadratic variation of shear strain through the plate thickness. Navier's method has been used to solve the governing equations for all edges simply supported boundary conditions. Analytical solutions of buckling of nano-scale plates are presented using this theory to illustrate the effect of nonlocal theory on buckling load of the nano-scale plates. The relations between nonlocal third-order and local theories are discussed by numerical results. Further, effects of (i) length (ii) nonlocal parameter, (iii) aspect ratio and (iv) mode number on nondimensional buckling load are studied. In order to validate the present solutions, the reference solutions are used and discussed. The present results of nano-scale plates using the nonlocal theory can provide a useful benchmark to check the accuracy of related numerical solutions.

• Journal of IKEEE
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• v.13 no.4
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• pp.116-124
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• 2009

Recently the CPU performance of modem chipsets or multimedia processors of mobile phone is as high as notebook PC. That is why mobile phone has been emerged as a leading ICON on the convergence of consumer electronics. The various applications of mobile phone such as DMB, digital camera, video telephony and internet full browsing are servicing to consumers. To meet all the demands the image quality has been increasingly important. Mobile phone is a portable device which is widely using in both the indoor and outside environments, so it is needed to be overcome to deteriorate image quality depending on environmental light source. Furthermore touch window is popular on the mobile display panel and it makes contrast loss because of low transmittance of ITO film. This paper presents the image enhancement algorithm to be embedded on image enhancement SoC. In contrast enhancement, we propose Clipped histogram stretching method to make it adaptive with the input images, while S-shape curve and gain/offset method for the static application And CIELCh color space is used to sunlight readability enhancement by controlling the lightness and chroma components which is depended on the sensing value of light sensor. Finally the performance of proposed algorithm is evaluated by using histogram, RGB pixel distribution, entropy and dynamic range of resultant images. We expect that the proposed algorithm is suitable for image enhancement of embedded SoC system which is applicable for the small-sized mobile display.

• The Journal of the Acoustical Society of Korea
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• v.36 no.6
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• pp.371-377
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• 2017

The performance of an air conditioner is closely related to the cooling performance of a split-type outdoor unit so that, in most of the relevant preceding studies, the independent performance of an axial fan in an outdoor unit has been studied. However, there is a lack of research on the effects of other components in an outdoor units was rarely investigated. Therefore, in this paper, the effects of the fan orifice among other parts on the flow performance of the outdoor unit was numerically investigated. A virtual fan tester consisting of 18 million grids was developed for highly resolved flow simulation. The unsteady RANS (Reynolds-averaged Navier-Stokes) equations are numerically solved by using finite-volume CFD (Computational Fluid Dynamics) techniques. In order to verify the validity of the numerical methods, the predicted P-Q curve of the cooling fan in a full outdoor unit is compared with the measured one. Optimization of orifice shape was carried out for maximum flow performance of the outdoor unit using the validated numerical method.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.39 no.6
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• pp.713-723
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• 2019

Due to the climate change and various rainfall pattern, it is difficult to estimate a rainfall criterion which cause inundation for urban drainage districts. It is necessary to examine the result of inundation analysis by considering the detailed topography of the watershed, drainage system, and various rainfall scenarios. In this study, various rainfall scenarios were considered with the probabilistic rainfall and Huff's time distribution method in order to identify the rainfall characteristics affecting the inundation of the Hyoja drainage basin. Flood analysis was performed with SWMM and two-dimensional inundation analysis model and the parameters of SWMM were optimized with flood trace map and GA (Genetic Algorithm). By linking SWMM and two-dimensional flood analysis model, the fitness ratio between the existing flood trace and simulated inundation map turned out to be 73.6 %. The occurrence of inundation according to each rainfall scenario was identified, and the rainfall criterion could be estimated through the logistic regression method. By reflecting the results of one/two dimensional flood analysis, and AWS/ASOS data during 2010~2018, the rainfall criteria for inundation occurrence were estimated as 72.04 mm, 146.83 mm, 203.06 mm in 1, 2 and 3 hr of rainfall duration repectively. The rainfall criterion could be re-estimated through input of continuously observed rainfall data. The methodology presented in this study is expected to provide a quantitative rainfall criterion for urban drainage area, and the basic data for flood warning and evacuation plan.

• Journal of the Korean Society of Marine Environment & Safety
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• v.15 no.4
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• pp.297-313
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• 2009

Long-term trends and distribution patterns of water quality were investigated in the Gunsan coastal areas of Yellow Sea, Korea from 1972 to 2006. Water samples were collected at 6 stations and physicochemical parameters were analyzed including water temperature, salinity, suspended solids(SS), chemical oxygen demand(COD), dissolved oxygen(DO) and nutrients. Spatial distribution patterns of temperature, DO and SS were not clear among stations but the seasonal variations were distinct except COD and SS. The trend analysis by principal component analysis(PCA) during 24 years revealed the significant variations in water quality in the study area. Spatial water qualities were clearly classified into 3 clusters by PCA; station cluster 1, 2~4, and 5~6. Annual water qualities were clearly classified into 4 surface water clusters and 5 bottom water clusters by PCA. By this multi-variate analysis. The annual trends were summarized as follows; Salinity, pH and DO tended to increase since late 1970's, COD to increase since 1987, and SS to decrease and nutrients to increase in Gunsan coastal waters due to the input of fresh water from land same as in Kyoungin coastal area, Asan coastal area and Choensoo bay.