• 대한수의학회지
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• 제25권2호
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• pp.103-112
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• 1985

국내에서 분리된 enterovirus의 병원성을 관찰하기 위하여 1~2일령의 자돈 10두와 35일 령의 유돈 6두에 enterovirus 조직배양부유액을 뇌내 또는 근육내 주사한 후 임상 및 병리학적으로 관찰하였던 바 다음과 같은 결과를 얻었다. 임상적으로는 체온의 상승, 보양창랑, 보행실조, 유약성 마비 및 고도의 삭수가 관찰되었다. 병리조직학적으로는 중추신경계 전반에 걸쳐 수막하 세포침윤, 혈관주위 원형세포침윤, 신경세포의 변성, 미만성과 한국성 gliosis, glial nodule의 형성 등이 관찰되었으며 백질부보다 회백질부에서 다소 심한 경향이었고 배측 신경절염이 전 실험예에서 인정되었다. 한편 hog cholera백신과 enterovirus의 공동주사예에서는 중추신경계의 병변이 enterovirus 단독주사예에 비해 급격히 진행되는 경향이었다. 이상의 소견들을 종합해 볼때 국내에서 분리된 enterovirus는 뇌내 또는 근육내에 접종하였을 때 자돈에서 polioencephalomyelitis를 일으킬 수 있는 병원성이 강한 형으로 추측되며 hog cholera백신과 enterovirus를 공동주사한 예에서 병변의 진행이 급격한 점으로 보아 enterovirus의 자연감염에 hog cholera 백신 등의 stress요인이 작용될 것으로 추측된다.

• 생명과학회지
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• 제19권8호
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• pp.1170-1176
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• 2009

Porcine reproductive and respiratory syndrome virus (PRRSV) has plagued pig populations worldwide causing severe economical impacts. In order to establish effective strategies for prevention of PRRS, infection patterns on the herd level are primarily evaluated. In the present study, therefore, serological and virological analyses were conducted in 20 pig farms suffering from PRRS. Seroprevalence levels in each farm were grouped into 3 patterns: SN (Stable sow groups/Not infected piglet groups, SI (Stable sow groups and Infected piglet groups), and UI (Unstable sow groups and Infected piglet groups). The rates of each serological pattern were 15% (n=3), 10% (n=2), and 75% (n=15), respectively. In addition, the pattern analysis was extended to virological monitoring on the same farms that further included suckling pig groups. As a result, the infection pattern was classified into 4 categories: SNI (Stable sow groups/Not infected suckler groups/Infected piglet groups), SII (Stable sow groups/Infected suckler groups/Infected piglet groups), UNI (Unstable sow groups/Not infected suckler groups/Infected piglet groups), and UII (Unstable sow groups/Infected suckler groups/Infected piglet groups). The rates of each viroprevalence were estimated at 50% (n=10), 30% (n=6), 10% (n=2), and 10% (n=2), respectively. PRRSV viroprevalence results of suckling pig groups revealed that 8 farms were considered virus positive. In 2 farms among these farms, PRRSV appeared to be transmitted vertically to suckling piglets from their sows. In contrast, piglet-to-piglet horizontal transmission of PRRSV seemed to occur in sucking herds of the remaining farms. Thus, this virological analysis on suckling piglets will provide useful information to understand PRRSV transmission routes during the suckling period and to improve a PRRS control programs. Our seroprevalence and viroprevalence data found that infection patterns between sow and piglet groups are not always coincident in the same farm. Remarkably, 15 farms belonging to the UI seroprevalence pattern showed four distinct viroprevalence patterns (SNI; 7, SII; 4, UNI; 2 and UII; 2). Among these farms, 11 farms with unstable seroprevalence sow groups were further identified as the stable viroprevalence pattern. These results indicated that despite the absence of typical seroconversion, PRRSV infection was detected in several farms, implying the limitation of serological analysis. Taken together, our data strongly suggests that both seroprevalence and viroprevalence should be determined in parallel so that a PRRS control strategies can be efficiently developed on a farm level.

• 조형예술학연구
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• 제13권1호
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• pp.61-86
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• 2008

불교와 불교미술은 인도에서 발원하였지만, 그것들은 각 나라에 전파되면서 국제적인 환경을 만들어 냈다. 불교는 각 나라에 일종의 꾸러미의 형식으로 전파되었다. 예를 들면 불경, 불상과 불화의 도상과 양식, 건축과 그 기법, 복잡한 의식, 승려나 여승이 기거하는 사찰에서 건축적 요소와 그 기법들이 함께 소개되었다 불교의 시작은 인도의 아쇼카 왕조시기(reign of King Asoka)로 거슬러 올라가지만, 이후 각 나라의 정치적, 지적, 예술적, 종교적, 사회적, 자연적 환경, 지리적, 지질적 환경에 맞게 전개됐다. 불교미술은 토착화하면서 그 지역민을 닮은 상이 만들어 졌고, 또 지역마다 독특한 특색을 나타내면서 발전하기 시작했다. 스투파(stupa)와 차이챠 홀(chaitya hall)은 수도원의 독특한 분위기를 만들어 내곤 중앙아시아의 대상인들은 인도의 문화가 중국에 전해지는데 공헌했을 뿐만 아니라, 그들이 지나던 교역루트의 자연환경 덕분에 화려한 색채의 벽화들이 제작되고 보존될 수 있었다. 불교와 불교 미술이 중국과 한국, 일본에 전해졌을 때, 불교는 국가 제도와 사회적 조직의 일부가 되었다. 정치적 목적에 의해 거대한 불상들이 산속의 동굴에 만들어 지기도 했다. 중국은 스투파를 사각형의 기둥으로 변형시켰고, 기와를 얹은 지붕 형식의 탑을 만들어 냈다. 한국은 불교미술을 중국에서 일본으로 전파시켰을 뿐만 아니라, 고유한 방식으로 그것을 변형시켰다. 석굴암의 깊은 명상에 잠긴 듯한 보살상들의 이미지가 그 좋은 예이다. 중국에서는 신유교 철학이 국-가의 공식적인 이념이 되면서 선종의 부흥하기도 했으며, 일본의 선승들은 신도들의 명상을 북돋기 위해 선종 형식의 정원을 만들어 냈다. 티벳의 밀교에서도 불교미술의 중요한 발전양상을 확인할 수 있다. 밀교의 미술은 예술적 환경 뿐만 아니라, 지적이고 종교적인 것에도 속한다. 한편 티벳의 신들이 그들의 배우자를 안고 있는 모습은 신과 신자들의 융합을 상징하기도 한다. 불교미술은 독창적인 환경을 만들어 냈고, 여라 나라에 전파되면서, 상당한 변화를 낳았다.

• 한국식품영양학회지
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• 제29권2호
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• pp.206-217
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• 2016

This study was conducted to assess the recognition and consumption of health functional food (HFF) of the college students in the Northern Gyeonggi-do area (Republic of Korea). To accomplish this, a survey was conducted to investigate 360 college students (183 males and 177 females) regarding their general characteristics, as well as the recognition, knowledge, considerations, purchases and consumption of HFF. Most male and female students (68.9% and 61.6%, respectively) were unaware of the HFF certification mark, however, more females(58.8%) were aware of the legal HFF definition compared to males (36.6%). The HFF advertising routes for males and females were 'TV radio' (43.2% and 43.5%, respectively) and 'internet smart phones' (19.7% and 27.1%, respectively). The main factor considered for selection and the most serious problem concerning HFF by males and females were 'effectiveness' (36.1% and 43.6%, respectively) and 'hype (exaggerated advertisement)' (35.0% and 55.9%, respectively). The main purchase route by males and females was 'pharmacy' (35.2% and 27.8%, respectively). The main reason for HFF product purchase by males and females was 'health promotion' (38.8% and 29.4%, respectively) and the main reason for not purchasing an HFF product was 'no health problem'(34.8% and 36.7%, respectively). The percentage of HFF consumption was 46.0% in males and 69.8% in females. The main HFF product consumed by males and females was 'vitamin mineral' (36.9% and 43.5%, respectively). The main reason for HFF consumption by males was 'health promotion' (31.0%) and females was 'recovery from fatigue' (21.8%). The main reason for not consuming HFF by males and females was 'no health problem' (38.4% and 41.5%, respectively). These results suggest the need to provide correct information concerning HFF to college students. Based on these results, greater efforts should be made to provide meaningful information regarding factors affecting purchase and consumption patterns for college students related to the research and development of HFF in the Northern Gyeonggi-do area.

• 한국화재소방학회논문지
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• 제34권4호
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• pp.52-58
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• 2020

노인인구의 증가와 맞벌이부부의 증가로 인한 노인부양방식의 변화로 중풍환자와 치매노인을 돌보는 노인의료복지시설이 급증하고 있다. 이러한 노인의료복지시설은 주로 도시의 주변에 설치되고 있으며 점차 고층화 되어가고 있다. 관리자가 최소인 야간에 화재발생 시 스스로 판단하여 대피할 수 있는 입소자들이 거의 없으며 경사로등 입소자를 대피시킬 수 있는 피난로가 없어 대형의 인명피해가 발생할 수 있다. 본 논문에서는 단위면적당 노인의료복지시설이 가장 많은 고양시를 중심으로 노인의료복지시설의 피난 상의 문제점을 파악하고 이에 대한 대안으로 경사로를 확보하거나 침대피난용 승강기를 확보하고, 입소자들의 침실을 한 시간 내화로 방화구획하며, 계단을 피난계단의 구조로 하며, 구조대 설치 등 피난에 필요한 시설들의 설치 및 주변기관과 화재 시 상호협력 하는 업무협약을 체결할 것을 제안하였다. 국가는 국민의 생명과 재산을 보호하는데 필요한 방안을 제시하여야 한다. 날로 증가되어가는 의료복지시설의 피난안전을 위하여 본 제안의 신속한 적용이 필요하다.

• 농약과학회지
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• 제15권4호
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• pp.507-528
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• 2011

포장에서 농약 살포액의 조제, 살포 등의 작업을 수행하는 농작업자는 피부노출, 호흡노출경로를 통해 농약에 노출되며, 이러한 상황에서의 농약 노출에 대한 합리적인 위해성 평가를 위해서는 해당 영농상황에서 노출량을 정량적으로 측정해야 한다. 농약 노출 측정방법으로 patch, 장갑, 양말, 마스크를 이용하는 방법과 호흡 노출은 주로 고체흡착제와 공기흡입펌프가 연결된 personal air monitor를 사용하는 것이 좋을 것으로 판단된다. 이 농작업자의 정량적 피부 노출 측정법으로 유효할 것으로 판단된다. 노출 재료에 침착/부착된 농약량이나 고체흡착제에 포집된 농약량을 신체 전체에 대한 농약 노출량으로 외삽하기 위한 EPA 자료를 대체할 수 있도록 한국 사람의 표준 신체표면적 및 호흡률을 제안하였다. 중요한 노출 인자인 피부노출의 의복 침투율과 피부 침투율, 그리고 호흡노출의 침투율을 UK-POEM과 관련된 연구결과를 참고하여 다양하게 제안하였다. 노출 평가를 위한 살포 시간은 노출 측정 재료에 침착된 농약이 분석이 될 만큼 충분한 농약이 포집될 수 있도록 살포시간이 충분해야 하는데, 국내의 SS기나 동력분무기의 경우는 1반복 당 모두 약 20~40분에 살포(약 0.1~0.2 ha)로 해서 3반복 측정 결과를 4시간으로 환산할 것을 제안하였다.

• 유통과학연구
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• 제13권12호
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• pp.95-103
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• 2015

Purpose - The Visegrád Group cooperation of the past 14 years and that of V4 for the past 20 years has very important significance in the 21st century that must be maintained. This cooperation is valuable because of the trade routes that connect northern Poland to the Balkans in southern Croatia, which forman important basis for the resuscitation of Central European development. Currently, because of the European manufacturing base and industrial development, an energy supply and stable energy distribution networks have been introduced to secure cooperation and not competition within the Visegrád Group. This paper's research emphasizes the supply chain hub in neighboring countries. Although Central and Eastern European countries are small, they can provide a competitive response to Western Europe if they collaborate with the V4 group and other countries. Research design, data, and methodology - The subjects of this study in the Visegrád Group area are related to the development of Marketing and Distribution Sciences in the integrated European Union. In relation to the existing energy infrastructure, construction companies and financial institutions benefit from large-scale construction projects. Existing or new infrastructure facilities among the V4 must comply with the preconditions of regional energy markets. The network of emerging markets is changing into a European-logistics hub of new markets. This hub is closely associated with the economic development of European self-sustainment given that energy for distribution and consumption is imported from Russia. Therefore, this paper indirectly provides data on the regional distribution of energy as alternative bases in Europe for market expansion to Asia. Results - As a result, it appeared unlikely that V4 failed to implement homogeneity following the standards of Western Europe, as proposed by the EU. Throughout European history, individuals have gathered in Central Europe as an innovation hub. Currently, the region is being established independently for energy industrial development and not for tourism development, and is expected to play a central role in innovation and distribution consumption. Therefore, similar to Western and Northern Europe, V4 only appears to engage in distribution consumption on the basis of the identity that it formed for itself. This area is expected to either create a regional platform or a voice over a single economic policy. Conclusions - To this end, regarding the distribution of consumer groups within and outside the region, the V4 group is expected to be established for various policy areas and as a Eurasian outpost of trade and distribution logistics. In addition, given its purpose of engaging in the distribution of energy cooperation and trade clusters, the Visegrád Group will be in charge of the center axis of the bridge for distribution logistics trading partners from the Western Balkans to Caucasus and Eastern Europe. Thus, the Visegrád Group is entering this region as a platform for market share by enabling all or any investor can gain greater industrial benefits.

• 유통과학연구
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• 제12권6호
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• pp.67-79
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• 2014

Purpose - This study aims to accomplish three major research goals. First, it strives to change consumers' focus from peripheral routes to a central route of public service advertising related to the good health policy, without problematic effects, by influencing consumers' knowledge or involvement. Second, this study examines the elaboration likelihood model (ELM) and construal level theory (CLT). Specifically, we consider that the central route of ELM might correspond with the focal goal of CLT. Third, this study analyzes ELM through CLT. That is, ELM predicted that low involvement would take the peripheral route, and high involvement would take the central route. Research design, data, and methodology - This study consisted of three experiments. The first experiment had a 2×2 between-subject design. The subjects were university students and the research period was approximately one year. The first independent variable was the involvement of the overweight issue; this variable was measured and split by the median. The second independent variable was the temporal distance (near vs. distant future); this variable was manipulated. The second experiment also had a 2×2 between-subject design. The first variable was the involvement of cervical adenocarcinoma prevention, and was considered already manipulated by sex. Specifically, males had a low involvement of the disease, but females had high involvement. The second independent variable was priming (power vs. submissive). Power priming would induce abstract thinking, but submissive priming would take concrete processing. The third experiment had a 2×2×2 between-subject design. The first variable was cognitive depletion, and was manipulated by memorizing 9-digit numbers. The second and third independent variables were involvement and abstract thinking induction, such as prior experiments. Data were collected through questionnaires, and were analyzed by an SPSS program. Major hypotheses were tested by examining the interaction effects through ANOVA. Results - Major findings are as follows. First, even for low-involved consumers in the overweight category, distant future manipulation induced them to focus not on the peripheral route but on the central route of the public service advertisement. This result does not correspond to the typical ELM prediction. Second, under power priming, low-involved males of the cervical adenocarcinoma category focused on the peripheral route because of the induction to abstract thinking. This result replicated the first experiment, and confirmed the theoretical robustness. Third, high-involved females focused not on the central but on the peripheral route under the mixed condition of cognitive depletion and near future manipulation. Depletion consumed cognitive resources, and the processing mode of consumers changed from systematic to heuristic. Conclusions - ELM needs to be complemented through CLT in context of public service good health advertising. Specifically, the involvement of ELM may impact consumers' thinking mode (abstract vs. concrete), and the interaction effects may influence consumers' focus on advertising (central vs. peripheral route). This study's limitations were bounded subjects, limited stimuli, and somewhat weak external validity.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제11권3호
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• pp.235-245
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• 2005

네트워크 기술의 발달에 힘입어 인터넷이 국가와 사회의 중요한 기반 시설로 자리잡고 있으며, 이를 통한 범죄적 동기를 갖는 해킹 사고의 증가 추세로 인해, 우리 사회 전반적으로 정보에 대한 보호가 시급한 문제로 대두되고 있다. 최근 침입의 형태는 기존 공격자의 직접적인 시스템 침입 및 악의적 행위들의 행사와는 달리 침입 자동화 도구들을 사용하는 형태로 변모해 가고 있다. 알려지지 않은 공격의 유형 또한 변형된 이들 도구들의 사용이 대부분이다. 이들 공격 도구들 대부분은 기존 형태에서 크게 벗어나지 않으며, 침입 도구의 산출물 또한 공통적인 형태로 존재한다. 본 논문에서는 멀티 에이전트 기반의 침입자 역 추적 시스템의 설계 및 구현에 관하여 기술하였다. 본 연구의 시스템은 우선, 알려지지 않은 다양한 공격을 기존 유사한 공격군으로 분류하기 위하여 SOM(Self-Organizing Maps)을 적용하였고, 침입 분석 단계에서는 공격 도구들의 패턴을 지식베이스로 정형화하였다. 이를 기반으로 에이전트 기반의 역 추적 시스템이 활성화 되고, 피 침입 시스템으로부터의 침입 흔적을 발견하여 이전 침입 경유 시스템으로의 경로를 자동으로 역 추적 하게 된다.

• Journal of Ginseng Research
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• 제42권4호
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• pp.401-411
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• 2018

Longevity in medicine can be defined as a long life without mental or physical deficits. This can be prevented by Alzheimer's disease (AD). Current conventional AD treatments only alleviate the symptoms without reversing AD progression. Recent studies demonstrated that Panax ginseng extract improves AD symptoms in patients with AD, and the two main components of ginseng might contribute to AD amelioration. Ginsenosides show various AD-related neuroprotective effects. Gintonin is a newly identified ginseng constituent that contains lysophosphatidic acids and attenuates AD-related brain neuropathies. Ginsenosides decrease amyloid ${\beta}$-protein ($A{\beta}$) formation by inhibiting ${\beta}$- and ${\gamma}$-secretase activity or by activating the nonamyloidogenic pathway, inhibit acetylcholinesterase activity and $A{\beta}$-induced neurotoxicity, and decrease $A{\beta}$-induced production of reactive oxygen species and neuro-inflammatory reactions. Oral administration of ginsenosides increases the expression levels of enzymes involved in acetylcholine synthesis in the brain and alleviates $A{\beta}$-induced cholinergic deficits in AD models. Similarly, gintonin inhibits $A{\beta}$-induced neurotoxicity and activates the nonamyloidogenic pathway to reduce $A{\beta}$ formation and to increase acetylcholine and choline acetyltransferase expression in the brain through lysophosphatidic acid receptors. Oral administration of gintonin attenuates brain amyloid plaque deposits, boosting hippocampal cholinergic systems and neurogenesis, thereby ameliorating learning and memory impairments. It also improves cognitive functions in patients with AD. Ginsenosides and gintonin attenuate AD-related neuropathology through multiple routes. This review focuses research demonstrating that ginseng constituents could be a candidate as an adjuvant for AD treatment. However, clinical investigations including efficacy and tolerability analyses may be necessary for the clinical acceptance of ginseng components in combination with conventional AD drugs.