• Animal cells and systems
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• v.6 no.1
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• pp.1-12
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• 2002

A role of Src family protein Tyrosine kinases (SFK) as mediators of receptor-ligand initiated responses is well established. Well documented, but less well understood is the role of SFK in cellular reaction to stresses. Evidence from the wide variety of experimental systems indicates that SFK mediate responses to all major classes of stress, including oxidation, DNA damage, mechanical impacts, and protein denaturing. SFK may be activated by stresses directly or via regulatory circuits whose identity is not yet fully understood. Depending on the cell type and the nature of activating stimulus, SFK may activate known downstream signaling cascades leading to cell survival, proliferation, cytoskeletal rearrangement, and apoptosis; the identity of these cascades is discussed. As in the case of receptor-initiated signaling, roles of individual SFK in various stress response may be redundant or non-redundant. Although signals generated by different stresses are generally transduced via distinct SFK pathways, these pathways may overlap or exhibit crosstalk. In some cell types stress-induced activation of SFK promotes survival and inhibits apoptosis, whereas the opposite may be true for other cell types. Stress responses constitute a new and rapidly developing area of SFK-mediated signaling.

• Journal of Fisheries and Marine Sciences Education
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• v.29 no.1
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• pp.80-89
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• 2017

The purpose of this research is to consider whether current science textbook is designed to let children properly obtain scientific knowledge through research study and at the same time provide an implication to help development of science textbook for the 2015 revised curriculum through comparing and analyzing of illustration in science textbooks of grade 5 and 6 published based on the 2007 curriculum and on the 2009 revised curriculum. The conclusion of comparison and analysis on illustration of the grade 5 and 6 science textbooks in the 2007 curriculum and the 2009 revised curriculum as follows. First, according to the comparison and analysis result on in the textbook, science textbook of year 2009 revised for grade 5 and 6 had 1.65 illustration per page and for the 2007 curriculum, it had 1.98 illustrations per page having 0.83 times more illustrations than that of the previous one. Second, the types of illustrations both textbooks had a higher ratio of pictures that are very detailed and objective which can identify scientific facts. In terms of role of illustration, illustrations providing various and realistic data related to the learning for students to have enough scientific experiences accounted for the most ratios.

• The Journal of Industrial Distribution & Business
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• v.9 no.7
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• pp.19-32
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• 2018

Purpose - This paper aims at exploring the effects of failure types such as failure in promotion orientation and failure in prevention orientation on consumers' consumption behavior, and the moderation role of lay theories in the effects. Research design, data, and methodology - This study employed 2 between-subject designs(failure in promotion orientation vs. failure in prevention orientation) and also 2 (failure in promotion orientation vs. failure in prevention orientation) with implicit self as the within-subject. Chinese consumers participated in the empirical study, and to verify the hypotheses ANOVA, T-test and regression analysis were used. Results - Consumers were more likely to choose adaptive consumption behavior rather than compensatory consumption behavior when they were encountered with failure in promotion orientation versus failure in prevention orientation. Lay theories did play the moderation role in the effect of failure types on consumption behavior. The incremental theorists who think that effort is an important way to accomplish their learning goals showed more willingness to conduct compensatory consumption behavior rather than adaptive consumption behavior. Conclusions - Marketers should put more attention on the ways by which their products can help consumers self-improve when consumers encounter with failure. They should also be aware of the importance of consumers' mindsets when designing and developing advertising messages.

• International Journal of Contents
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• v.16 no.3
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• pp.66-86
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• 2020

With the rapid growth of high-tech, the development of cultural and creative industries has gradually become the focus of national industrial development. With the proposal of China's "Belt and Road" strategy, the role of cultural and creative industries in the provinces and cities along the "Belt and Road" in the entire international trade is becoming increasingly critical. It is necessary to explore solutions to improve the competitiveness of China's cultural and creative industries, factoring the surrounding cities of the "Belt and Road" as an example. Thus, this paper proposes the six-element diamond model based on innovation capability and government support to render a comprehensive evaluation of the competitiveness of the cultural and creative industries in the 31 provinces and cities across the country. The results show that the overall competitiveness of the 18 provinces and cities along the "Belt and Road" cultural and creative industries is weak. Focusing on the 18 provinces and cities along the "Belt and Road", using the linear regression measurement model quantitative analysis, the four types of influencing factors affecting the development of the competitiveness of cultural and creative industries along the "Belt and Road" were obtained. Finally, according to the four types of influence, the competitiveness improvement plan is proposed from the four aspects: government role, consumption preference, industrial innovation ability, and the introduction of high-quality talent.

• Journal of Distribution Science
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• v.17 no.9
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• pp.15-23
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• 2019

Purpose - This study was aimed to investigate the moderating effects of cobranding promotions that are rare in brand experience and brand loyalty studies, and to find out cobranding promotions can play a moderating role to enhance positive effects on the relationship between brand experience and brand loyalty, and to figure out the cobranding types which can lead to positive brand loyalty. Research design, data, and methodology - The conceptual research model was developed to explain the effects, and 2018 Interbrand's global top 15 brands such as Apple, Google, Amazon, Samsung were suggested to be selected from 377 Amazon Mechanical Turk respondents to answer the 22 survey questions made by Qualtrics with 5-point Likert scale. Results - In this research, the moderating effects of cobranding have been confirmed on the relationships between brand experience and loyalty, and the positive cobranding promotions can have significant effects on the relationships, but only for the least experienced brand was significant. Regarding to cobranding types, there were no significant ones to enhance brand loyalty. Conclusions - The findings confirmed that cobranding promotion experience can play a positive moderating role to brand loyalty, and the loyalty can be maximized if companies can provide positive cobranding experiences to their own consumers.

• Journal of the Korean Home Economics Association
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• v.36 no.10
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• pp.35-48
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• 1998

The Korean family is changing. The growth in dual-earner households has been the 'revolution' of the century, implying inevitable modification of the role division in marriage toward greater symmetry of responsibility for breadwinning and homemaking. So, the purpose of this study is to understand husbands' housework and to investigate the change of the husbands' housework. This means to investigate how the husband is related to housework. For these research purpose, 60 dual-earner couples were deeply interviewed. The major discussions of this study can be summarized as follows: There are four types of housework in men's work, the type of refusal, the type of avoidance, the type of inevitability, and the type of participation. These types are taken order to understand change in housework is women's work. Men in the type of avoidance in household work is 25%, they have a tendency to avoid housework with making any excuses. People in the type of inevitability is 20%. These men are compelled to work in household owing to circumstances beyond control. 13% of couples is type of participation. These have a new idea of housework. They don't get the gender role division. They can become a good husband. and eventually solve conflicts and problems in couples.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.1
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• pp.44.2-44.2
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• 2014

We investigate the influence of neighboring galaxies as a component of the local environment. Based on the SDSS data release 7 and the KIAS value-added galaxy catalog, we have constructed a galaxy pair catalog by matching each galaxy with its nearest and its most tidally-influential neighbor. In particular, we examine the star formation rate (SFR) derived from their optical u-r color and $H{\alpha}$ emission as functions of neighbor's distance, tidal force, and morphological type. The results are as follows. (1) The $H{\alpha}$-based SFR of galaxies with close companions is enhanced by up to a factor of three regardless of neighbor's morphology, when compared to isolated counterparts. (2) The mean u-r color of galaxies along with early-type galaxies is redder than that of isolated ones, yet bluer with late-types. (3) The galaxies with late-type companions mostly show higher SFR than those with early-types. The results suggest that the role played by neighboring galaxies are two-fold; (a) the tidal effect on the shorter scale of time and of distance, and (b) the hydrodynamic effect on the longer scale.

• Journal of East-West Nursing Research
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• v.19 no.2
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• pp.78-87
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• 2013

Purpose: This study has investigated experience of middle aged women who attended a self help group to overcome midlife crisis. Methods: To analyze types of experience that middle aged women attending the self help group went through to overcome midlife crisis, Q-methodology has been used. The 32 selected Q-samples from each of 27 subjects were classified into a shape of normal distribution using a 9-point scale. The collected data were analyzed using a QUANL PC program. The 38 selected Q-samples from each of 27 subjects were classified into a shape of normal distribution using a 9-point scale. The collected data were analyzed using a QUANL PC program. Results: The types of experience were classified into four categories; Type I (attempt to change), Type II (devoted to my role), Type III (tolerance and acceptance) and Type IV (role as a senior citizen). Conclusion: This study is significant in that it has attempted to analyze the approach and usefulness of a self-help group program. It is suggestive that a local society support group may be necessary to help people with midlife crisis and further studies for nursing intervention and strategic development are required.

• Korea journal of population studies
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• v.25 no.1
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• pp.213-256
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• 2002

A woman faced with choices regarding contraception has several sources of information which may influence her decision Among these are other women's ideas as well as their reported behavior. Applying a two-stage econometric model to data on married women taken from a study of Korean social networks. this Paper assesses the relative impacts of the two information sources above. In addition, this Paper (1 ) considers the role of social and opinion leadership in the impact of a family Planning Program by Postulating two different social influence factors, (2) explores which types of social network contacts most significantly amplify the impact of the family Planning program, and (3) discusses the effects of two types of family Planning Program efforts: the inputs of family planning field workers, and the use of indigenous women's groups.

• Computers and Concrete
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• v.17 no.6
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• pp.739-760
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• 2016

This paper reports on punching shear behavior of reinforced concrete panels, investigated experimentally and through finite element simulation. The aim of the study was to examine the punching shear of high strength concrete panels incorporating different types of aggregate and silica fume, in order to assess the validity of the existing code models with respect to the role of compressive and tensile strength of high strength concrete. The variables in concrete mix design include three types of coarse aggregates and three water-cementitious ratios, and ten-percent replacement of silica fume. The experimental results were compared with the results produced by empirical prediction equations of a number of widely used codes of practice. The prediction of the punching shear capacity of high strength concrete using the equations listed in this study, pointed to a potential unsafe design in some of them. This may be a reflection of the overestimation of the contribution of compressive strength and the negligence of the role of flexural reinforcement. The overall findings clearly indicated that the extrapolation of the relationships that were developed for normal strength concrete are not valid for high strength concrete within the scope of this study and that finite element simulation can provide a better alternative to empirical code Equations.