• 응용통계연구
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• 제24권5호
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• pp.861-869
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• 2011

최근 유전학에서 주요 목표중 하나는 복합질환에 영향을 미치는 유전적 요인을 찾아내는 것이다. 유전자좌간의 상호작용이 있을 때에는 단일 유전자좌 분석으로는 이러한 목표를 달성하기 어려우므로, 유전자-유전자간 상호작용이나 유전자-환경인자간 상호작용분석을 고려할 필요가 있다. 자주 사용되는 MDR(multifactor dimensionality reduction)방법은 데이터를 고위험군과 저위험군으로 각각 병합하여 사용하므로 특정 유전자형에서 차이가 나는 경우에는 이를 찾아내기 어렵다. 본 연구에서는 이러한 점을 보완하도록 유전자형 조합에서의 대조군과 질환군의 상대위험도를 이용하여 유전자-유전자간 상호작용을 탐색하는 방법을 제안하였다. MDR 공개데이터와 8가지 유전모형으로부터 생성한 모의자료의 분석을 통해 방법의 유용성을 확인하였다.

• 대한두개안면성형외과학회지
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• 제10권1호
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• pp.33-36
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• 2009

Purpose: Fractures of the mandibular condylar area are common injuries that account for 29% to 40% of fractures of the facial bones and represent 20% to 62% of all mandibular fractures. Currently 3 main methods are being used in the treatment of mandibular subcondylar fractures: closed reduction; open reduction and internal fixation; Endoscopic reduction and internal fixation. Each method has its proponents and opponent as well as advantages and disadvantages, and indications for each vary among surgeons. There are six approaches of open reduction: submandibular, retromandibular, preaurilcular, postauricular, intraoral, transparotid approach. Among them, transparotid approach has been described for subcondylar exposure with dissection in the direction of facial nerve fibers to expose the bone through the parotid gland. This approach carries the risk of a parotid glandular fistula as well as facial nerve injury but has the advantage of being directly over the fracture site. We report safety and efficacy of surgical treatment using a transparotid approach for direct plating. Methods: A 43-year-old man sustained multiple facial bone fractures by driver traffic accident. Mandibular subcondyle was fractured and dislocated internally. We performed open reduction and internal fixation by transparotid approach. Fractured site was fixed by titanium mini plate & screw. We applicated arch bar for approximately 3 weeks. Results: Follow-up length was about 5months. Scar of surgical incision was indistinct, there was no symptoms and signs of facial nerve and parotid gland injury, and maximal mouth opening was measured 49.5 mm. Conclusion: Transparotid approach has high risks of facial nerve and parotid gland injury, but paradoxically it is the most effective technique in saving facial nerve. Open reduction and internal fixation of mandibular subcondylar fracture by transparotid approach with precise and versed procedure, best outcome can be expected.

• 자원ㆍ환경경제연구
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• 제18권3호
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• pp.495-521
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• 2009

본고는 식품위험이 현실화되지 않은 상황에서 건강위해에 대한 심리적 불안과 우려로 인하여 발생할 수 있는 소비감소와 후생손실을 2008년 4월 미국산 쇠고기 수입재개 발표에 따른 BSE 위험을 사례로 분석하였다. 조건부가치측정법이나 실험시장접근법을 사용하여 식품안전에 대한 소비자들의 단위당 지불의사나 가격프리미엄을 도출했던 기존의 연구들과는 달리, 소비자들이 기록한 쇠고기 구입량, BSE 위험에 대한 주관적 심각성, 표본내 개인들이 직면한 가격지수 등을 산정하여 개인별 쇠고기 수요함수를 추정하고 소비자들이 주관적으로 체험하는 정확한 후생효과인 동등변화(EV)와 소비자잉여의 변화를 측정함으로써 소비자들이 식품안전성에 부여하는 가치를 측정하였다. 2008년 10월 말부터 11월 중순까지 쇠고기를 소비하는 360명의 주부들을 대상으로 실시한 설문조사 자료를 사용하여 쇠고기 수요함수를 추정한 결과, 수입재개 발표 전 후의 경우 모두 자체 가격, 대체재의 가격, 그리고 소득변수 등의 부호가 경제이론에 부합되었고 통계적으로 유의하였으며 발표 전 후 두 기간 동안에 큰 차이가 관찰되지 않았다. 반면에 수업재개 발표 이후 형성된 BSE 위험에 대한 심각성을 나타내는 변수는 발표 이후의 수요함수에서는 통계적으로 유의한 부의 부호를 가진 반면에, 발표 이전의 수요함수에서는 통계적으로 유의하지 않았다. 그리하여 수입재개 발표 후의 BSE 위험에 대한 우려증가로 인한 품질저하 인식에 따른 소비자들의 후생손실을 측정한 결과 가구당 30,000원 정도로 계산되었다. 또한 이 정도의 후생손실을 가져올 BSE 위험에 대한 우려수준은 수입재개 전에 비하여 35% 이상 증가한 것으로 나타났다.

• 한국환경보건학회지
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• 제34권2호
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• pp.124-130
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• 2008

This study investigated the age dependencies in ambient air pollution-associated asthma hospitalization from 2003 to 2005 in Seoul. For all ages and the age groups of 0-14, 15-64, and 65+years, the Generalized Additive Model (GAM) was used to estimate the relative risks of daily asthma hospitalization associated with changes in particulate matter and ozone. The time-trends, seasonal variances, day effects, temperature, humidity, and pressure at sea level were controlled in the models. Significant associations were observed between asthma hospitalization and the levels of $PM_{10}$ and $O_3$. The relative risks (RRs) of asthma hospitalization for every 10 unit increases in $PM_{10}({\mu}g/m^3)$ and $O_3$(ppb) were 1.008 (95% CI 1.005-1.012), and 1.012 (95% CI 1.003-1.020), respectively. Evaluated over $10\;{\mu}g/m^3$ increase in $PM_{10}$, we found the relative risks of asthma hospitalization to be 1.009 (95% CI 1.004-1.014) in 0-14 age group, and 1.015 (95% CI 1.008-1.022) in 65+ age group. Considering 10 ppb increase in $O_3$, those were 1.014 (95% CI 1.003-1.024) in 0-14 age group, and 1.025 (95% CI 1.009-1.041) in 65+ age group. It was concluded that current levels of ambient air pollution in Seoul make a significant contribution to the variation in daily asthma hospitalization. Further reduction in air pollution is necessary to protect the health of the community, especially that of the higher risky groups including children and elderly population.

• 복식문화연구
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• 제26권3호
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• pp.450-470
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• 2018

This study examined the risk components and risk types perceived in the context of purchasing decisions of paper fashion products. This study also identified the levels of perceived risk by consumers and the differences between age groups in risk perception. First, qualitative data were collected through a focus group interview with 7 Korean females in their 20s to 50s. The interviewees were presented with two types of paper materials (undyed and dyed Jumchi-Hanji) and products (bags and wallets) made with the papers. The interviewees mentioned 11 risk components which were classified into five types of risks: performance (easily torn/lack of durableness, lint/pilling/wear-out, lack of water-resistant, no washability, and deformation and discoloration over time), social-psychological (old and traditional image), aesthetic (lack of design diversity, unsatisfactory appearance due to repair), financial (expensive price, lack of usability in daily life) and time/convenience (difficulty in handling) risks. Based on the results of the interview, a measurement for evaluating the risk perception of paper fashion products was developed. Second, quantitative data were collected from 64 Korean women in their 20s to 50s using the measurement. Respondents who were presented with the paper materials and the products perceived the performance risk more strongly than the social-psychological risk and aesthetic risk. In addition, differences between age groups were found: younger respondents perceived performance risk and social-psychological risk more strongly than older respondents, but older respondents perceived financial risk more than younger respondents. Based on this study, strategies for the risk reduction of paper fashion products were proposed.

• 기술혁신연구
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• 제26권4호
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• pp.1-28
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• 2018

자동차 부품기업들은 플랫폼 기반 대량맞춤형 제품개발과 생산을 통해 비용절감과 아시아 신흥시장 수주 확대를 목표로 하고 있다. 그러나 신흥시장은 수주량이 적고, 변동성이 높아 목표 달성이 어렵다. 본 연구는 부품기업 관점에서 신흥시장의 수주량 변동성 위험을 적정 수준으로 관리하면서, 영업이익을 극대화할 수 있는 제품 포트폴리오 최적화 방법을 제안한다. 기존 제품 포트폴리오 최적화 접근법과의 차별점은 세가지다. 첫째, 플랫폼 기반 대량맞춤형 생산에 의한 비용 절감효과를 반영한다. 둘째, 수주량 변동성을 고려한다. 셋째, 최소 영업이익률 유지라는 강건성 조건을 반영한다. 실무적으로는 신흥시장 개척의 재무 위험을 최소한도로 유지하면서, 점진적으로 시장점유율을 높여가는 동적 제품개발 전략 수립의 토대를 제공한다. 북미, 유럽, 아시아 18개 업체에 납품하는 다국적 부품제조기업의 파워리프트게이트 제품을 대상으로 실증연구를 수행했다.

• 한국프랜차이즈경영연구
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• 제13권4호
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• pp.39-48
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• 2022

Purpose: COVID-19 has negatively influenced the financial performance of restaurant firms. Previous literature suggests that the franchising strategy effectively helps restaurant firms recover from difficult business conditions through various methods for expanding business size and enhancing business efficiency. According to risk-sharing theory, restaurant franchisors may minimize operational risks by sharing the risks with their franchisees. For instance, restaurant franchisors could generate more stable cash flow using franchise fees from their franchisees. However, research on the effect of franchise's risk reduction factor on business performance during pandemic is scarce. Thus, this study aims to examine the positive moderating effect of franchising between COVID-19 and restaurants' financial performance. Research design, data, and methodology: Panel data including financial information and franchising status of restaurant firms were collected for analysis. In order to control for unobserved firm-specific factors, generalized least squared estimation in fixed effects model was conducted. Huber-White robust standard errors were used to deal with heteroscedasticity issues. Results: It was found that COVID-19 pandemic has a negative effect on the restaurants' financial performance such as ROA (return on assets), ROE (return on equity), and PM (profit margins), which confirms the findings from existing literature. More importantly, results show that the degree of franchising has a positive moderating effect on the relationship between COVID-19 and financial performance of restaurant firms. This suggests that more active engagement in franchising may decrease negative impacts of COVID-19 on the restaurants' financial performance. Conclusions: The study supports existing literature related to risk-sharing theory, by confirming that pandemics, such as COVID-19, negatively affect financial performance of the restaurants. Furthermore, it was found that franchising strategy can help lessen negative impacts of pandemics on the firm performance. These findings can contribute to the franchise and restaurant management literature by suggesting the role of franchising in reducing business risks, thereby positively affecting financial performance. Moreover, this study offers business managers of franchisors and franchisees insights for utilizing franchising in restaurant risk management. Policymakers may also gain information on aiding restaurant firms during global crisis, such as COVID-19.

• Journal of Plant Biotechnology
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• 제6권1호
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• pp.1-7
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• 2004

Forestry sector has witnessed some unprecedented events in the recent past both in terms of galloping biotechnological developments and heated environmental debates over risks associated with release of transgenic trees. Improvements in the in vitro propagation techniques has made it possible to develop tissue culture based plant regeneration protocols just for about any tree species. And with the inclusion of every new species within the realms of tissue culture technology, it becomes a candidate for genetic improvement through recombinant DNA technology, the so called genetic engineering. Poplars and their hybrids serve as the model tree species on which most of the genetic transformation work as been carried out. A lot of work has also gone in genetic transformation of fruit trees and trees of horticultural interests. Trees have been successfully transformed for traits ranging from reduction of length of juvenile phase to alteration of tree architecture to altering wood quality by lignin and cellulose modification. More-over trees have been genetically engineered successfully to combat various types of insect pests and pathogens causing diseases. But all these developments have ignited controversies over the possible benefits and risks associated with transgenic plantations by various environmental agencies and activists. Solutions to most of these concerns can be found out with more intensive prioritized research.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 추계학술대회논문집
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• pp.880-883
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• 2006

The reduction of tool vibration has been a serious issue for both employers and workers because of the risks of vibration transmitted to the workers. In this study a hand-arm vibration measurement and evaluation system was developed based on ISO 5349:2001 and used for analyzing relation of vibration level and components of tools. This system consists of a notebook PC installed a LabVIEW program and the data acquisition system including two 3-axial accelerometers and a NI-DAQ card. Vibration measurement tests were conducted for eight angle grinders and four impact wrenches where 3 subjects were used for each of the tools. The relation between different components of each tool and its vibration total value made it possible to set-up a guideline of tool design. In the past engineers developed tools by using their experience and intuition, but by using this system it became possible to design tool components so as to minimize the risks of hand-transmitted vibration.

• 교육시설 논문지
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• 제23권1호
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• pp.23-32
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• 2016

This research aims to securement of crime prevention for school violence and invasion from outside etc. For crime prevention efficiency secure, It has purpose for school current state comprehension and prevention essential elements deduction autonomously etc. Furthermore, school facility crime dangerousness evaluation checklist is looked for autonomous monitoring tools. This checklist made from analysis of frequency, importance and check availability of 6 native and foreign existing CPTED evaluation's 360 indexes. Then, 81 indexes was derived from analysis, and that indexs verified through focus group interview. Finally, total 47 articles checklist emerged with general details, external school, internal school, and school administrative managements. Through this checklist, school can select essential elements of the preferential crime prevention autonomously, and so it is expected to prompt improvement of crime dangerousness elements, school violence and reduction of crime rate.