• 제목/요약/키워드: Risk function

검색결과 1,720건 처리시간 0.022초

한국의 건강검진 현황 (Current Status of Health Screening in Korea)

  • 조한익
    • 한국건강관리협회지
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    • 제2권2호
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    • pp.215-230
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    • 2004
  • Along with a development of medical technology, a variety of tests, such as laboratory tests, x-ray and endoscopies are being used in health screening tests. As the tests determine the quality of health screening, test items and methods should be carefully selected. This study was to get hold of the test items of major health screening programs in Korea. Most of the health screening programmes focused upon detection of risk factors and diagnosis of life-style related diseases(diabetes, hypertension, cardiovascular diseases, hypercholesterolemia, overweight, drinking, smoking, cerebrovascular diseases, osteoporosis) ,cancers(stomach, cervix, lung, breast, liver, colon, prostate, ovary, pancreas, thyroid, esophagus), infectious diseases (hepatitis, tuberculosis, sexually-transmitted diseases, parasites),chronic obstructive respiratory diseases, chronic renal diseases(bacteriuria, hematuria, proteinuria), anemia, glaucoma, hearing loss, Alzheimer disease, stress, early Psychiatric diseases. The health screening tests were basic physical examination, basic laboratory tests(CBC, urinalysis, liver function tests, lipid tests, glucose, HbAlc, uric acid, electrolytes, serological tests(HBsAg, HBs-Ab, HCV-Ab, HIV-Ab, VDRL) EKG, x-ray(chest PA, CT), endoscopy (gastroscopy, colonoscopy) , sonography(abdormen, thyroid, pelvis, breast) , cytology(cervix) ,bone density, tumor markers(NMP22, alpha-FP, CEA, CA-19-9, CA12S, PSA) and eye tests. Advanced technologies, like CT, PET, MIRI, MIRI/Angio, molecular testings) were widely usedin hospital health screening programmes. In summary, a variety of were utilized by stages or programmes, however a few subjects. tests were utilized in health screening in Korea. Those tests according to sex and age in most of health screening program used tests to excess disregarding health screening subject.

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Association between Genetic Variation in the Human Antithrombin III Gene and Essential Hypertension in Korean Population

  • Shin, Jung-Hee;Kang, Byung-Yong;Kim, Ki-Tae;Lee, Kang-Oh;Kim, Jae-Hyoun;Om, Ae-Son;Oh, Sang-Duk;Lee, Chung-Choo
    • 한국환경성돌연변이발암원학회지
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    • 제22권1호
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    • pp.30-38
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    • 2002
  • In view of the effect of antithrombin III on essential hypertension, we investigated the 5' untranslated exon 1 length (I/D) polymorphism and intron 5'-DdeI RFLP of the human antithrombin III gene in the Korean patients with essential hypertension. There were no significant differences in the allele, genotype and haplotype frequencies of these polymorphisms between normotensive and essential hypertensive subjects. The significant linkage disequilibrium was however, detected between I/D polymorphism and Dde I RFLP. The I/D polymorphism was also significantly associated with BMI, total cholesterol (TC) and HDL- cholesterol levels, while DdeI polymorphism with age and BMI. Therefore, our results suggest that the significant association between the genetic polymorphisms in the antithrombin III gene and variable cardiovascular risk factors may reflect the potential role of human antithrombin III gene in cardiovascular function.

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LNG 플랜트 공정계통의 실패율이 가용도에 미치는 영향에 관한 연구 (A Study on the Availability with Failure Rate of Process for LNG Plant)

  • 강경원;윤명오;이홍철;황인주
    • 설비공학논문집
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    • 제24권4호
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    • pp.358-363
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    • 2012
  • The simulation investigation on the availability of LNG plant with scenario of failure events and failure rate has been carried out. This study focuses on the availability, productivity, criticality induced by failure rate of major equipment. The methodologies for simulation such as the equipment classification of LNG plant and failure type and event schematic are established. The availability and mean time to repair have second order function profile in the all cases except general equipment, but these profiles have different inclination. The production and criticality of the specified LNG plant, simulated by Monte-Carlo algorithm, is located in the range of P = 86~92% and PL = 6~13%.

운동선수들의 혈액분석을 통한 Etrythropoietin 간접도핑검사 (Blood Analysis for Indirect Doping Control of Erythropoietin in Sports)

  • 이정란;김소영;홍지연;김명수;최명자
    • 약학회지
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    • 제47권6호
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    • pp.422-431
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    • 2003
  • The use of recombinant human erythropoietin (rhEPO), a stimulator of erythropoiesis, banned in sports because of the medical risk associated with thrombosis. Due to analytical difficulties to differentiate between natural human EPO (hEPO) and rhEPO, blood parameters of erythropoiesis such as contents of hemoglobin (cut-off value <17.5 g/d l for man, and < 16.0 g/dl for women), hematocrit and reticulocytes (cut-off value <2.0%) were measured to focus the misuse of rhEPO. We conducted anti-doping test for 122 blood samples of the World Cup athletes. The mean values of key parameters are as follows; 14.5$\pm$1.0 g/dl for hemoglobin, 41.7$\pm$2.8% for hematocrit, and 1.3$\pm$0.4% for reticulocyte. Blood sample was found to be stable up to 8 hours for the reticulocyte measurement. In addition, the soluble transferrin receptor and ferritin levels were measured by immunoassay methods using plasma samples (n=28) in which the mean value was 0.8$\pm$0.5 $\mu\textrm{g}$/$m\ell$ and 54.6$\pm$33.7 ng/$m\ell$, respectively. The results indicate that all samples tested were negative for the blood parameters of indirect anti-doping test for hEPO misuse. The statistical evaluation suggest that several other parameters such as red blood cell, mean corpuscular hemoglobin concentration, mean corpuscular volume, mean corpuscular hemoglobin and white blood cell could be considered as factors influencing hEPO function in addition to five parameters mentioned.

Thermal cracking analysis of concrete with cement hydration model and equivalent age method

  • Tian, Ye;Jin, Xianyu;Jin, Nanguo
    • Computers and Concrete
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    • 제11권4호
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    • pp.271-289
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    • 2013
  • In this research, a developed microstructural model of cement particles was presented to describe the cement hydration procedure. To simplify the hydration process, the whole hydration was analyzed in a series of sub-steps. In each step, the hydration degree, as well as the microstructural size of the hydration cell, was calculated as a function of the radius of the unreacted cement particles. With the consideration of the water consumption and the reduction of the interfacial area between water and hydration products, the micro-level expressions of the cement hydration kinetics were established. Then the heat released and temperature history of the concrete was carried out with the hydration degree obtained from each sub-steps. The equivalent age method based on the Arrhenius law was introduced in this research. Based on the equivalent age method, a maturity model was applied to describe the evolution of the mechanical properties of the material during the hydration process. The finite element program ANSYS was used to analyze the temperature field in concrete structures. Then thermal stress field was calculated using the elasticity modulus obtained from code formulate. And the risk of thermal cracking was estimated by the comparison of thermal stress and concrete tensile strength.

ETA를 이용한 에너지저장시스템의 위험성 평가 (Risk Assessment of Energy Storage System using Event Tree Analysis)

  • 김두현;김성철;김의식;박영호
    • 한국안전학회지
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    • 제31권3호
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    • pp.34-41
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    • 2016
  • The purpose of this paper is to conduct ETA on six items of ESS: the whole system, battery, BMS, PCS, ESS and cable. To achieve that, ESS work flow and its components are categorized. Based on performance, human, environmental, management, and safety, this paper drew initiation events (IE) and end states (ES). ETA is applied to the main functions of each item, and the end states that may occur in one initiation event are suggested. In addition, detailed classification was performed to induce various end states on the basis of the suggested initiation events ; loss of grid electricity of ESS, loss of battery electricity(DC) of battery, impairment of electric function of BMS, loss of grid electricity(AC) of PCS, loss of data of EMS, Mechanical damage of cable, event sequence analysis conducted on the basis of event trees. If the suggested IEs and ESs are applied on the basis of ESS event cases, it is expected to prevent the same kinds of accident and operate ESS safely.

Practical Use and Risk of Modafinil, a Novel Waking Drug

  • Kim, Dong-Soo
    • Environmental Analysis Health and Toxicology
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    • 제27권
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    • pp.7.1-7.7
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    • 2012
  • Objectives: Modafinil is a waking drug prescribed to narcolepsy patients, but its usage among healthy individuals is increasing to enhance their alertness or to mitigate fatigue. This study was conducted to investigate practical use and toxic effects on neuro-immune interaction of modafinil. Methods: This study reviewed the significance of psychoactive drugs, and discussed the benefits and risks of the application of modafinil, which seems to be ideal as an anti-psychotic or anti-fatigue agent. Results: Modafinil is known to have less or no adverse effects than those found in traditional psychostimulants such as amphetamine, methylphenidate or cocaine. It can be applied as an anti-psychotic or anti-fatigue agent. However, the waking mechanism of modafinil is yet to be fully revealed. Recent studies reported that modafinil may be subject to abuse and addiction. In addition prolonged sleeplessness induces stress responses and impairs immune function. Conclusions: Modafinil can be used by anyone, who wishes to work late, stay awake, enhance their cognitive reactions, or brighten their moods. Users may already be under a great level of stress, i.e. cancer patients or soldiers in a battle field. A psychoneuroimmunological approach is thus needed to investigate the multi-functional effects of modafinil.

회전근 개 질환의 자연경과 (Natural History of Rotator Cuff Disorders)

  • 오정환;박진영
    • 대한정형외과스포츠의학회지
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    • 제3권2호
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    • pp.93-97
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    • 2004
  • 회전근 개의 전층 파열은 운동, 고정, 약물 등의 치료로 재생되기 어렵다. 파열은 시간이 지나면서 격심한 통증은 없어질 수 있으나, 대부분의 환자에서 어깨나 머리 위로 다시 움직일 때 증상이 재발된다. 작은 파열은 진행할 수 있으며, 광범위한 파열 시 통증이 감소될 수 있으나 점진적인 근력 약화가 동반된다. 치료 받지 않은 회전근 개 파열 환자의 일부는 견관절 관절염이 속발될 수 있다. 보존적 방법으로 치료하여도 증상이 지속될 때, 증상을 호전 시키고 기능을 회복시키는 가장 좋은 방법은 수술적 봉합이다.

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IoT 단말기에서 증거추출 포렌식 연구 (Extract of evidence on the IoT Device)

  • 송진영;박대우
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2017년도 추계학술대회
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    • pp.343-345
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    • 2017
  • IoT 기술의 발달로 IoT와 연계된 단말기가 활용되고 있다. 하지만 IoT가 사회 전반에 활용되면서 보안사고가 발생하고 있다. IoT 보안 사고는 개인의 위험과 사회의 혼란으로 연결될 수 있다. 본 연구에서는 IoT 스마트워치 단말기에서 보안 침해사고가 발생한 증거를 추출한다. IoT 보안 침해사고 환경을 분석하고 원본성과 무결성을 확보하기 위한 Hashing 함수를 추출한다. 그리고 IoT 스마트워치 단말기에서 Forensic 증거를 추출하여 원본성과 무결성을 검증하고 Forensic 보고서를 작성하여 법적 증거자료로 채택되도록 연구한다.

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와이파이를 이용한 도어락 원격제어 시스템 (Door lock remote control system using Wi-Fi)

  • 김기범;김동현
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2017년도 추계학술대회
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    • pp.86-88
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    • 2017
  • 디지털 도어락은 비밀번호 방식을 적용한 전자식 도어락이며, 문을 닫을 때 자동으로 문을 잠궈주는 기능이 있어 외출 시 문단속에 대한 걱정을 없애주었다. 이러한 편의성을 무기로 점차 시장이 확대되어 나갔으며, 기술이 점차 발전함에 따라 반도체 키 방식, RFID, 지문인식 등 여러 가지 인증 기술이 추가로 도입되었다. 그러나 도어락 키의 복사 위험이 있고, 비밀번호 도용 및 침해가 있다. 이 논문에서는 사용자가 이러한 위험을 보완하기 위해 스마트 폰으로 잠금을 해제 하거나 열 수 있는 원격제어 시스템을 개발한다. 개발하려는 시스템은 와이파이를 이용하여 스마트 폰으로 문이 잠금이 되었는지 열려있는지 확인이 가능하고, 원격으로 문을 잠그거나 열 수 있다.

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