• Korean Journal of Radiology
• /
• 제25권6호
• /
• pp.518-539
• /
• 2024

Coronary computed tomography angiography (CCTA) has emerged as a pivotal tool for diagnosing and risk-stratifying patients with suspected coronary artery disease (CAD). Recent advancements in image analysis and artificial intelligence (AI) techniques have enabled the comprehensive quantitative analysis of coronary atherosclerosis. Fully quantitative assessments of coronary stenosis and lumen attenuation have improved the accuracy of assessing stenosis severity and predicting hemodynamically significant lesions. In addition to stenosis evaluation, quantitative plaque analysis plays a crucial role in predicting and monitoring CAD progression. Studies have demonstrated that the quantitative assessment of plaque subtypes based on CT attenuation provides a nuanced understanding of plaque characteristics and their association with cardiovascular events. Quantitative analysis of serial CCTA scans offers a unique perspective on the impact of medical therapies on plaque modification. However, challenges such as time-intensive analyses and variability in software platforms still need to be addressed for broader clinical implementation. The paradigm of CCTA has shifted towards comprehensive quantitative plaque analysis facilitated by technological advancements. As these methods continue to evolve, their integration into routine clinical practice has the potential to enhance risk assessment and guide individualized patient management. This article reviews the evolving landscape of quantitative plaque analysis in CCTA and explores its applications and limitations.

• Nuclear Engineering and Technology
• /
• 제40권5호
• /
• pp.327-348
• /
• 2008

A risk-informed regulatory approach implies that risk insights be used as supplement of deterministic information for safety decision-making purposes. In this view, the use of risk assessment techniques is expected to lead to improved safety and a more rational allocation of the limited resources available. On the other hand, it is recognized that uncertainties affect both the deterministic safety analyses and the risk assessments. In order for the risk-informed decision making process to be effective, the adequate representation and treatment of such uncertainties is mandatory. In this paper, the risk-informed regulatory framework is considered under the focus of the uncertainty issue. Traditionally, probability theory has provided the language and mathematics for the representation and treatment of uncertainty. More recently, other mathematical structures have been introduced. In particular, the Dempster-Shafer theory of evidence is here illustrated as a generalized framework encompassing probability theory and possibility theory. The special case of probability theory is only addressed as term of comparison, given that it is a well known subject. On the other hand, the special case of possibility theory is amply illustrated. An example of the combination of probability and possibility for treating the uncertainty in the parameters of an event tree is illustrated.

• 한국가스학회지
• /
• 제26권6호
• /
• pp.52-58
• /
• 2022

정부의 수소 경제 활성화 로드맵에 따라 다양한 산업 분야에서 액화수소를 에너지원으로 하는 사업을 진행하고 있고, 액화수소 설비 및 취급시설의 제작 및 운영 실증 사업 또한 수행되고 있다. 그러나 운영 실증사업에 필요한 안전기준이 국내에는 마련되지 않아 실증 사업의 걸림돌로 작용하고 있어 조속한 안전기준 마련이 필요한 실정이다. 따라서 액화수소 설비 및 취급시설의 안전성 확보를 위하여 액화수소의 위험성을 종합적으로 고려한 안전기준의 마련이 반드시 필요하다고 본다. 본 연구에서는 일반적인 방법과 같이 국외사고 사례 분석 및 유사 분야의 안전기준을 참고로 도출한 선박용 액화수소 사용 시설 안전기준을 위험성 평가기법인 ETA, FMEA와 의사 결정방법인 AHP를 활용해 안전기준 항목의 우선순위 도출하여 안전기준 항목 선정에 타당성을 제시하고자 한다.

• Safety and Health at Work
• /
• 제12권4호
• /
• pp.496-504
• /
• 2021

Background: With the increasing demand for industrial robots and the "noncontact" trend, it is an appropriate point in time to examine whether risk assessments conducted for robot operations are performed effectively to identify and eliminate the risks of injury or harm to operators. This study discusses why robot accidents resulting in harm to operators occur repetitively despite implementing control measures and proposes corrective actions for risk assessments. Methods: This study collected 369 operator-injured robot accidents in Korea over the last decade and reconstructed them into the mechanism of injury, work being undertaken, and bodily location of the injury. Then, through the techniques of Systematic Cause Analysis Technique (SCAT) and Root Cause Analysis (RCA), this study analyzed the root and direct causes of robot accidents that had occurred. Causes identified included physical hazards and complex combinations of hazards, such as psychological, organizational, and systematic errors. The requirements of risk assessments regarding robot operations were examined, and three case studies of robot-involved tasks were investigated. The three assessments presented were: camera module processing, electrical discharge machining, and a panel-flipping robot installation. Results: After conducting RCA and comparing the three assessments, it was found that two-thirds of injury-occurring from robot accidents, causative factors included psychological and personal traits of robot operators. However, there were no evaluations of the identifications of personal aspects in the three assessment cases. Conclusion: Therefore, it was concluded that personal factors of operators, which had been overlooked in risk assessments so far, need to be included in future risk assessments on robot operations.

• 대한원격탐사학회지
• /
• 제28권1호
• /
• pp.129-143
• /
• 2012

이 논문은 1986년에 발생한 체르노빌 원전 사고 사례연구를 통해 환경 모니터링과 영향 평가를 위한 고급 공간정보 모델링 기술의 유용성을 예시하였다. 사고지점 주변에서 1986년과 1992년에 촬영된 Landsat TM 영상자료를 대상으로 선분류 후비교법을 적용하여 변화가 크게 일어난 지역과 토지피복 변화 양상을 분석하였다. 그리고 이 사고의 가장 큰 피해지역으로 알려진 벨로루시 지역을 대상으로 다양한 크리깅 기법을 포함한 공간 모델링 기법을 적용하여 토양 내 세슘 농도와 갑상선 암 발병률 자료와의 상관성을 분석하였다. 변화 탐지 결과, 농경지 면적의 감소와 황무지 면적의 증가가 가장 뚜렷하게 나타났고, 방사능 오염의 확산을 막기 위한 콘크리트 구조물들이 새롭게 생겨난 것을 확인할 수 있었다. 벨로루시 지역의 영향평가 결과, 세슘 오염이 심한 원전 인근 지역에서 포아송 크리깅에 의해 추정된 위험도가 상대적으로 높게 나타났다. 세슘 농도와 사고지점과의 거리를 독립 변수로 사용하여 이 변수들의 공간 변화 양상을 반영할 수 있는 지리적 가중 회귀분석을 적용하였다. 적용 결과, 갑상선 암 위험도와 상관계수 0.98을 나타내는 갑상선 암 발병 위험도 추정이 가능하였으며, 이는 원전 사고가 갑상선 암 발병 위험도에 영향을 준 것을 의미한다. 결론적으로 이 연구에서 적용한 공간정보 모델링 기법들은 환경 영향 평가 및 환경 보건 분야에서 유용하게 사용될 수 있을 것으로 기대된다.

• 한국항해항만학회지
• /
• 제34권3호
• /
• pp.213-220
• /
• 2010

최근 IMO에서는 산적화물선 및 유조선, 대형여객선에 이어 '일반화물선의 안전(general cargo ships safety)'에 대한 논의의 필요성이 제기(IMO, 2006a)되고 있으며, 본격적인 논의를 위한 준비 작업으로 국제선급협회(IACS)를 통한 공식안전성평가(Formal Safety Assessment, 이하 FSA) 작업이 수행되고 있다. FSA란 위험도(risk)분석과 비용-효과 평가(cost-benefit assessment)를 바탕으로 인명, 해양환경 및 재산의 보호를 포함한 해사안전의 향상을 목적으로 한 구조화되고 체계적인 방법론으로서 새로운 법규의 평가, 기존법규와 새로운 (제안) 법규와의 비교, 그리고 여러 이해관계자의 공감대 형성을 통해 법규 변경/개발을 용이하게 하는 수단이다(IMO, 2007). 본 연구는 국적일반화물선의 안전성 평가를 위한 수단으로서 IMO FSA방법론의 유용성을 확인하고, 향후 IMO에서의 '일반화물선 안전'에 대한 논의에 대응하기 위한 기초자료의 확보를 목적으로 하고 있다. 본 논문에서는 국적일반화물선에 대한 FSA의 1, 2 단계에 해당하는 위험요소 식별(Hazard identification) 및 사고시나리오에 대한 위험도 분석(Risk analysis) 결과를 중심으로 소개하였다.

• 대한수의학회지
• /
• 제47권2호
• /
• pp.259-263
• /
• 2007

The choice of input distribution in quantitative risk assessments modeling is of great importance to get unbiased overall estimates, although it is difficult to characterize them in situations where data available are too sparse or small. The present study is particularly concerned with accommodation of uncertainties commonly encountered in the practice of modeling. The authors applied parametric and non-parametric bootstrap simulation methods which consist of re-sampling with replacement, in together with the classical Student-t statistics based on the normal distribution. The implications of these methods were demonstrated through an empirical analysis of trade volume from the amount of chicken and pork meat imported to Korea during the period of 1998-2005. The results of bootstrap method were comparable to the classical techniques, indicating that bootstrap can be an alternative approach in a specific context of trade volume. We also illustrated on what extent the bias corrected and accelerated non-parametric bootstrap method produces different estimate of interest, as compared by non-parametric bootstrap method.

• Journal of Ship and Ocean Technology
• /
• 제5권3호
• /
• pp.1-13
• /
• 2001

Present-day rules and regulations for the design and construction of ships are almost without exemption of a prescriptive and deterministic nature. Often it is argued that this situation is far from ideal; it does no right to the advances, which have been made during the past decades in engineering tools in marine technology, both in methodology and in computational power. Within IMO this has been realized for some time and has resulted in proposals to use Formal Safety Assessment(FSA) as a tool to improve and to modernize the rule making process. The present paper makes use of elements of the FSA methodology, but instead of working towards generic regulations or requirements, a Risk Assessment Approach, not unlike a 'safety case'; valid for a certain ship or type of ship is worked out. Delft University of Technology investigated the application of safely assessment procedures in ship design, in co-operation with Anthony Veder Shipowners and safety experts from Safely Service Center BV. The ship considered is a semi-pressurized-fully refrigerated LPG carrier. On the basis of the assumption that a major accident occurs, various accident, scenarios were considered and assessed, which would impair the safety of the carrier. In a so-called Risk Matrix, in which accident frequencies versus the consequence of the scenarios are depicted, the calculated risks all appeared lo be in the ALARP('as low as reasonable practicable') region. A number of design alternatives were compared, both on safety merits and cost-effectiveness. The experience gained with this scenario-based approach will be used to establish a set of general requirements for safety assessment techniques in ship design. In the view that assessment results will be most probably presented in a quasi-quantified manner, the requirements are concerned with uniformity of both the safety assessment. These requirements make it possible that valid comparison between various assessment studies can be made. Safety assessment, founded on these requirements, provides a validated and helpful source of data during the coming years, and provides naval architects and engineers with tools experience and data for safety assessment procedures in ship design. However a lot of effort has to be spent in order to make the methods applicable in day-to-day practice.

• Nuclear Engineering and Technology
• /
• 제19권4호
• /
• pp.279-291
• /
• 1987

현재 원자력발전소의 확률론적 위해도 평가에 사용되는 사상 수목이나 고장수목 기법은 부품이나 계통의 이원적상태와 정적 묘사에 근거하고 있다 이 기법이 대부분의 안전해석에는 적합하지만, 요사이 점차 중요관심사가 되고 있는 발전소의 이용률 측정이나 기술 사양서 평가 같은 문제를 정확하게 다루기 위해서는 마코프 신뢰도 분석과 같은 보다 진보된 기법이 필요하다. 이 논문은 가압경수로의 원자로 보호계통을 위한 마코프 신뢰도 모델을 기술하고 기술사양서의 두 검사 절차를 분석한 결과를 제시한다.

• 환경영향평가
• /
• 제9권4호
• /
• pp.363-372
• /
• 2000

For any particular development project or environmental regulations, decision-making criteria is required and conflicts among criteria should be resolved. It is necessary to investigate criteria that government agencies employ in making decisions that influence the environment. The evaluation of alternative development proposals and regulatory measures involves much more than environmental issues. Economic, technical, and social factors should be considered along with environmental impacts when making evaluations. Evaluation should be based on values of all individuals who may be affected by public or private decisions. There are many evaluation methods for determining how individuals and groups value alternative public actions. Numerous weighting-scaling methodologies can be used in such evaluations. These methodologies represent adaptations of multiple-criteria or multiple-attribute decision-making techniques. Environmental risk assessment which accounts for uncertainties in choosing among alternative policies and projects is increasingly used.